Harnessing Microbial Volatile Organic Compounds for Crop Protection: Scientific Discovery, Bridging Ecological Function and On‐Farm Application

Microbial volatile organic compounds (VOCs) are integral to microbial ecological communication. Their potential as tools for sustainable crop protection is increasingly recognised, yet practical implementation remains limited. There are numerous in vitro lab‐based studies focussed on screening single strains of soil or plant‐associated microbes for their ability to produce VOCs and demonstrate their potential to inhibit plant pathogens or pests. Most of these, however, lack any validation in planta or in the field after petri dish experiments. This extends to a lack of understanding on whether the same VOCs are produced in vitro as in planta. How do we shift this focus and move from exciting lab‐based discoveries to practical, scalable crop protection solutions for farmers? This opinion piece explores the current state of research on microbial VOCs for crop protection, translational challenges in deploying them on‐farm, and highlights areas where learnings from the ecological roles of microbial VOCs can be leveraged towards field application.

• Publication year

  2026

• Venue

  Microbial Biotechnology

• Publication date

  2026-02-01

• Fields of study

  Agricultural and Food Sciences, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/1751-7915.70313PMID 41649049PMCID 12878796
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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