Generation of Destabilized Herpes Simplex Virus Type 1 Thymidine Kinase as Transcription Reporter for PET Reporter Systems in Molecular–Genetic Imaging

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Nuclear Medicine

• Publication date

  2007-12-12

• Fields of study

  Medicine, Chemistry, Engineering

• Identifiers
  DOI 10.2967/jnumed.106.038943PMID 18077523
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vitro evaluation of herpes simplex virus type 1 thymidine kinase reporter system in dynamic studies of transcriptional gene regulation.

  2006influential reference
• Real-time imaging of hypoxia-inducible factor-1 activity in tumor xenografts.

  2005cited by this paper
• Mechanisms of Protein Degradation: An Odyssey with ODC

  2005cited by this paper
• Proteolysis: from the lysosome to ubiquitin and the proteasome

  2005cited by this paper
• The antizyme family: Polyamines and beyond

  2005cited by this paper
• Degradation of Antizyme Inhibitor, an Ornithine Decarboxylase Homologous Protein, Is Ubiquitin-dependent and Is Inhibited by Antizyme*

  2004cited by this paper
• Proteasomes Begin Ornithine Decarboxylase Digestion at the C Terminus*

  2004cited by this paper
• Imaging the spatial distribution of transgene expression in the lungs with positron emission tomography

  2003cited by this paper
• Molecular-genetic imaging: current and future perspectives.

  2003cited by this paper
• Molecular imaging in living subjects: seeing fundamental biological processes in a new light.

  2003cited by this paper
• Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes

  2003cited by this paper
• Cytoplasmically retargeted HSV1-tk/GFP reporter gene mutants for optimization of noninvasive molecular-genetic imaging.

  2003cited by this paper
• Advances in in vivo bioluminescence imaging of gene expression.

  2002cited by this paper
• Noninvasive imaging of protein–protein interactions in living animals

  2002cited by this paper
• The ubiquitin-proteasome pathway of intracellular proteolysis.

  2002cited by this paper
• PET imaging of gene expression.

  2002cited by this paper
• The proteasome inhibitor MG132 promotes accumulation of the steroidogenic acute regulatory protein (StAR) and steroidogenesis

  2001cited by this paper
• Ubiquitin and proteasomes: Regulation of cellular polyamines by antizyme

  2001cited by this paper
• Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK

  2000cited by this paper
• Ubiquitin‐mediated proteolysis: biological regulation via destruction

  2000cited by this paper
• Fertile Homozygous Transgenic Mice Expressing a Functional Truncated Herpes Simplex Thymidine Kinase ΔTK Gene

  1998cited by this paper
• Proteasome inhibitors: valuable new tools for cell biologists.

  1998cited by this paper
• Generation of Destabilized Green Fluorescent Protein as a Transcription Reporter*

  1998influential reference
• Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy.

  1996cited by this paper
• PEST sequences and regulation by proteolysis.

  1996cited by this paper
• A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice

  1995cited by this paper
• ATP- and antizyme-dependent endoproteolysis of ornithine decarboxylase to oligopeptides by the 26 S proteasome.

  1994cited by this paper
• Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme

  1992cited by this paper
• Targeted degradation of c-Fos, but not v-Fos, by a phosphorylation-dependent signal on c-Jun.

  1992cited by this paper
• Modulation of firefly luciferase stability and impact on studies of gene regulation.

  1991cited by this paper
• Characterization of sequences involved in mediating degradation of ornithine decarboxylase in cells and in reticulocyte lysate.

  1991cited by this paper
• Trypanosome ornithine decarboxylase is stable because it lacks sequences found in the carboxyl terminus of the mouse enzyme which target the latter for intracellular degradation.

  1990cited by this paper
• The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53.

  1990cited by this paper
• Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation.

  1989cited by this paper
• Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition.

  1987cited by this paper
• Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.

  1986cited by this paper

• Encapsulin Based Self-Assembling Iron-Containing Protein Nanoparticles for Stem Cells MRI Visualization

  2021cites this paper
• Molecular Imaging of Stem Cell Therapy in Ischemic Cardiomyopathy

  2021cites this paper
• Protein Engineering for Molecular Imaging

  2021cites this paper
• Gain of CXCR7 function with mesenchymal stem cell therapy ameliorates experimental arthritis via enhancing tissue regeneration and immunomodulation

  2021cites this paper
• Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling

  2020cites this paper
• Molecular Imaging of Stem Cells

  2019influential citation
• Reporter gene technologies for imaging cell fates in hematopoiesis.

  2014cites this paper
• IMAGING CELL THERAPY

  2013cites this paper
• Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy Applications

  2012cites this paper
• Mono- and dimethylbenzyls as new protecting groups for no-carrier-added nucleophilic aromatic radiofluorination

  2011cites this paper
• Imaging Cancer Stem Cells

  2011cites this paper
• Molecular Imaging with Reporter Genes: Molecular Imaging with Reporter Genes

  2010cites this paper
• Construction of Mutant TKGFP for Real-Time Imaging of Temporal Dynamics of HIF-1 Signal Transduction Activity Mediated by Hypoxia and Reoxygenation in Tumors in Living Mice

  2009cites this paper
• Molecular imaging of stem cells

  2009cites this paper
• Seeing genes at work in the living brain with non-invasive molecular imaging.

  2009cites this paper
• Current awareness in contrast media and molecular imaging.

  2008cites this paper