Ubiquitin and proteasomes: Regulation of cellular polyamines by antizyme

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Nature reviews. Molecular cell biology

• Publication date

  2001-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/35056508PMID 11265248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A proteasome howdunit: the case of the missing signal.

  2000cited by this paper
• Proteasomes: The World of Regulatory Proteolysis

  2000cited by this paper
• Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit

  2000cited by this paper
• Identi®cation and characterization of testis speci®c ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting

  2000cited by this paper
• Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes

  2000cited by this paper
• Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.

  2000cited by this paper
• Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.

  2000cited by this paper
• Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases.

  1999cited by this paper
• Functional interaction between GCN5 and polyamines: a new role for core histone acetylation

  1999cited by this paper
• Antizyme2 Is a Negative Regulator of Ornithine Decarboxylase and Polyamine Transport*

  1999cited by this paper
• ATP-Dependent Inactivation and Sequestration of Ornithine Decarboxylase by the 26S Proteasome Are Prerequisites for Degradation

  1999cited by this paper
• Sensitivity to polyamine-induced growth arrest correlates with antizyme induction in prostate carcinoma cells.

  1999cited by this paper
• A Guide to the Polyamines

  1998cited by this paper
• Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase*

  1997cited by this paper
• Is hypusine essential for eukaryotic cell proliferation?

  1997cited by this paper
• Polyamine transport in mammalian cells. An update.

  1996cited by this paper
• Cloning of Antizyme Inhibitor, a Highly Homologous Protein to Ornithine Decarboxylase (*)

  1996cited by this paper
• Ornithine decarboxylase antizyme: a novel type of regulatory protein.

  1996cited by this paper
• Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme

  1995cited by this paper
• Identification of an endogenous inhibitor of prostatic carcinoma cell growth

  1995cited by this paper
• Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase.

  1995cited by this paper
• Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

  1994cited by this paper
• Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells.

  1994cited by this paper
• Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylase

  1994cited by this paper
• Antizyme delays the restoration by spermine of growth of polyamine-deficient cells through its negative regulation of polyamine transport.

  1994cited by this paper
• Polyamines and regulation of spermatogenesis: selective stimulation of late spermatogonia in transgenic mice overexpressing the human ornithine decarboxylase gene.

  1993cited by this paper
• Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein

  1993cited by this paper
• Enhancement of the spermidine uptake system and lethal effects of spermidine overaccumulation in ornithine decarboxylase-overproducing L1210 cells under hyposmotic stress.

  1993cited by this paper
• Hypusine is essential for eukaryotic cell proliferation.

  1993cited by this paper
• A novel type of regulatory protein for the GDP/GTP exchange reaction of rho p21, a ras p21-like small GTP-binding protein, in rabbit intestine

  1992cited by this paper
• Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

  1992cited by this paper
• Destabilization of ornithine decarboxylase by transfected antizyme gene expression in hepatoma tissue culture cells.

  1992cited by this paper
• Cloning and characterization of a rat gene encoding ornithine decarboxylase antizyme.

  1992cited by this paper
• Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.

  1991cited by this paper
• Analyses of ornithine decarboxylase antizyme mRNA with a cDNA cloned from rat liver.

  1990cited by this paper
• Polyamine transport in mammalian cells.

  1990cited by this paper
• Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation.

  1989cited by this paper
• Role of antizyme in degradation of ornithine decarboxylase in HTC cells.

  1985cited by this paper
• Polyamines.

  1984cited by this paper
• The preparation and properties of gel-filtered rabbit-reticulocyte lysate protein-synthesis systems.

  1983cited by this paper
• Purification and some properties of ornithine decarboxylase from rat liver.

  1982cited by this paper
• Cadaverine and putrescine initiate the burial of dead conspecifics by rats.

  1981cited by this paper
• Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction.

  1976cited by this paper
• Control of ornithine decarboxylase activity in stimulated human lymphocytes by putrescine and spermidine.

  1973cited by this paper
• Amine synthesis in regenerating rat liver: extremely rapid turnover of ornithine decarboxylase.

  1969cited by this paper
• Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.

  1968cited by this paper
• Chemical Carcinogenesis 1

  year unknowncited by this paper

• Genetically encoded fluorescent reporter for polyamines

  2025cites this paper
• Evolution, composition and functions of cullin E3 ubiquitin ligases in trypanosomes

  2025cites this paper
• Metabolism of Polyamine in Vascular Diseases: An Prospective Therapeutic Target

  2025cites this paper
• Small molecule targeted protein degradation via the UPS: venturing beyond E3 substrate receptors.

  2025cites this paper
• Integrating bioinformatics, molecular dynamics simulation and experimental verification to screen diagnostic biomarkers for polyamine metabolism-related osteoarthritis and predict potential drugs

  2025cites this paper
• Polyamines buffer labile iron to suppress ferroptosis

  2025cites this paper
• Preventing Cancer by Inhibiting Ornithine Decarboxylase: A Comparative Perspective on Synthetic vs. Natural Drugs

  2024cites this paper
• Protein degradation of antizyme depends on the N‐terminal degrons

  2024cites this paper
• Genetically encoded fluorescent reporter for polyamines

  2024influential citation
• MicroRNA-34 and gastrointestinal cancers: a player with big functions

  2024cites this paper
• C-Methylated Spermidine Derivatives: Convenient Syntheses and Antizyme-Related Effects

  2023cites this paper
• EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration

  2023cites this paper
• Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows.

  2023cites this paper
• Metabolic landscape dysregulation in bronchoalveolar lavage fluid of checkpoint inhibitor pneumonitis.

  2023cites this paper
• Metabolism of Polyamines and Kidney Disease: A Promising Therapeutic Target

  2023cites this paper
• ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport

  2023cites this paper
• Functional analysis of xlAZIN2 in a heterologous cell system.

  2023cites this paper
• Bachmann–Bupp syndrome and treatment

  2023cites this paper
• SIN-3 transcriptional coregulator maintains mitochondrial homeostasis and polyamine flux

  2023influential citation
• Re-reading the genetic code: The evolutionary potential of frameshifting in time

  2022cites this paper
• Herpesvirus-induced spermidine synthesis and eIF5A hypusination for viral episomal maintenance.

  2022cites this paper
• Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions

  2022cites this paper
• Epithelial protein lost in neoplasm (EPLIN)-β is a novel substrate of ornithine decarboxylase antizyme 1, mediating cellular migration

  2022cites this paper
• Little involvement of recycled-amino acids from proteasomal proteolysis in de novo protein synthesis.

  2022cites this paper
• The Potential Role of Polyamines in Epilepsy and Epilepsy-Related Pathophysiological Changes

  2022cites this paper
• Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae

  2022influential citation
• Function of Polyamines in Regulating Cell Cycle Progression of Cultured Silkworm Cells

  2021cites this paper
• Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development

  2021cites this paper
• Regulation of polyamine homeostasis through an antizyme citrullination pathway

  2021cites this paper
• DFMO feeding lowers polyamine levels and causes developmental defects in the silkworm Bombyx mori

  2021cites this paper
• Role of Antizyme Inhibitor Proteins in Cancers and Beyond

  2021cites this paper
• The Regulation of Polyamine Pathway Proteins in Models of Skeletal Muscle Hypertrophy and Atrophy - a potential role for mTORC1.

  2021cites this paper
• The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

  2021cites this paper
• Polyamine Homeostasis in Development and Disease

  2021cites this paper
• Fungal Enzyme l-Lysine α-Oxidase Affects the Amino Acid Metabolism in the Brain and Decreases the Polyamine Level

  2020cites this paper
• Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase

  2020cites this paper
• Polyamine biosynthesis and eIF5A hypusination are modulated by the DNA tumor virus KSHV and promote KSHV viral infection

  2020cites this paper
• Putrescine regulates nitric oxide accumulation in Ganoderma lucidum partly by influencing cellular glutamine levels under heat stress.

  2020cites this paper
• Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells.

  2020cites this paper
• Modulation of AMPA Receptors by Nitric Oxide in Nerve Cells

  2020cites this paper
• FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer

  2020cites this paper
• A masked initiation region in retinoblastoma protein regulates its proteasomal degradation

  2020cites this paper
• Ubiquitin-Independent Proteasomal Degradation Mediated by Antizyme

  2020cites this paper
• Polyamine biosynthesis in Xenopus laevis: the gene xlAZIN2/xlODC2 encodes a lysine decarboxylase

  2019cites this paper
• Polyamine biosynthesis in Xenopus laevis: the xlAZIN2/xlODC2 gene encodes a lysine/ornithine decarboxylase

  2019cites this paper
• Effect of Cell-Free Supernatant from Aeromonas sobria on the Spoilage of Shewanella putrefaciens in Pacific White Shrimp (Litopenaeus vannamei) with the Influence of Temperature Fluctuation

  2019cites this paper
• Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives

  2019cites this paper
• Critical Factors in Human Antizymes that Determine the Differential Binding, Inhibition, and Degradation of Human Ornithine Decarboxylase

  2019cites this paper
• Precision Control of CRISPR-Cas9 Using Small Molecules and Light.

  2019cites this paper
• Polyamine Metabolism as a Therapeutic Target in Hedgehog-Driven Basal Cell Carcinoma and Medulloblastoma

  2019cites this paper
• Analysis of the Ornithine Decarboxylase Antizyme RNA Structure and Function

  2019cites this paper
• Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2

  2018cites this paper
• Analysis of Cotranslational Polyamine Sensing During Decoding of ODC Antizyme mRNA.

  2018cites this paper
• New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility

  2018cites this paper
• Significance of A‐to‐I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics

  2018cites this paper
• Ubiquitin‐independent, Proteasome‐mediated targeted degradation of KRAS in pancreatic adenocarcinoma cells using an engineered ornithine decarboxylase/antizyme system

  2018cites this paper
• Polyamine synthesis as a target of MYC oncogenes

  2018cites this paper
• Antizyme Inhibitors in Polyamine Metabolism and Beyond: Physiopathological Implications

  2018cites this paper
• Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells

  2018cites this paper
• An overview of polyamine metabolism in pancreatic ductal adenocarcinoma

  2018cites this paper
• Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

  2018cites this paper
• Evaluation of the spoilage potential ofShewanella putrefaciens,Aeromonas hydrophila, andAeromonas sobriaisolated from spoiled Pacific white shrimp (Litopenaeus vannamei) during cold storage

  2018cites this paper
• Micellar electrokinetic chromatography with laser induced fluorescence detection shows increase of putrescine in erythrocytes of Parkinson's disease patients.

  2018cites this paper
• The old and new biochemistry of polyamines.

  2018cites this paper
• OAZ1 knockdown enhances viability and inhibits ER and LHR transcriptions of granulosa cells in geese

  2017cites this paper
• Elucidating the anti-cancer mechanisms for transition-state structure inhibitors of nucleoside phosphorylases methylthioadenosine-DADMe-immucillin A and forodesine

  2017cites this paper
• Effect of Oaz1 overexpression on goose ovarian granulosa cells

  2017cites this paper
• Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

  2017cites this paper
• Study on the spoilage potential of Pseudomonas fluorescens on salmon stored at different temperatures

  2017cites this paper
• A 20S proteasome receptor for degradation of intrinsically disordered proteins

  2017cites this paper
• Polyamines, folic acid supplementation and cancerogenesis

  2017cites this paper
• Physiological importance of polyamines

  2017cites this paper
• Effects of agmatine on secretion of interferon tau and catecholamines and expression of genes related to production of polyamines by ovine trophectoderm cells

  2016cites this paper
• Genome‐scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells

  2016influential citation
• Role of Urinary Biomarkers in the Diagnosis of Adenoma and Colorectal Cancer: A Systematic Review and Meta-Analysis

  2016cites this paper
• Genetic subdivision and candidate genes under selection in North American grey wolves

  2016cites this paper
• ATP13A3 and caveolin-1 as potential biomarkers for difluoromethylornithine-based therapies in pancreatic cancers.

  2016cites this paper
• Agmatine mediated hypertonic stress development in Schizophrenia: a Novel study

  2016cites this paper
• Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells.

  2016cites this paper
• Targeting polyamine metabolism for cancer therapy and prevention.

  2016cites this paper
• Recoding: reprogrammed genetic decoding with an emphasis on antizyme regulatory frameshifting

  2016cites this paper
• import by hypoxia in pulmonary artery endothelial cells Regulation of ornithine decarboxylase and polyamine

  2016cites this paper
• In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms

  2016cites this paper
• Degrons of yeast and mammalian ornithine decarboxylase enzymes make potent combination for regulated targeted protein degradation

  2016cites this paper
• Biosynthesis of polyamines and polyamine-containing molecules.

  2016cites this paper
• Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use

  2016cites this paper
• A novel role for antizyme inhibitor 2 as a regulator of serotonin and histamine biosynthesis and content in mouse mast cells

  2016cites this paper
• A MELHORA DA RECONSOLIDAÇÃO DA MEMÓRIA INDUZIDA PORESPERMIDINA ENVOLVE A PROTEÍNA CINASE DEPENDENTE DE CÁLCIO

  2015cites this paper
• Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines

  2015cites this paper
• Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1

  2015cites this paper
• Screening of potential targets in Plasmodium falciparum using stage-specific metabolic network analysis

  2015cites this paper
• Polyamines directly promote antizyme-mediated degradation of ornithine decarboxylase by the proteasome

  2015cites this paper
• Metabolic markers associated with high mannose glycan levels of therapeutic recombinant monoclonal antibodies.

  2015cites this paper
• Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).

  2015cites this paper
• Polyamine-independent Expression of Caenorhabditis elegans Antizyme*

  2015cites this paper
• Structural basis of antizyme-mediated regulation of polyamine homeostasis

  2015cites this paper
• Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

  2015cites this paper
• Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor

  2015cites this paper
• CHARACTERIZATION OF MITOTIC REGULATORS ACM1 AND CDC14

  2015cites this paper
• Involvement of Antizyme Characterized from the Small Abalone Haliotis diversicolor in Gonadal Development

  2015cites this paper