The level of CD8 expression can determine the outcome of thymic selection.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Cell

• Publication date

  1992-06-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0092-8674(92)90631-LPMID 1617724
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CD8 is needed for development of cytotoxic T but not helper T cells

  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
• CD8 is needed for development of cytotoxic T cells but not helper T cells.

  1991cited by this paper
• On the complexity of self

  1991cited by this paper
• Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules

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• Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand.

  1991cited by this paper
• Co-engagement of CD8 with the T cell receptor is required for negative selection

  1991cited by this paper
• Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

  1991cited by this paper
• Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

  1991cited by this paper
• Evidence for CD8-independent T cell maturation in transgenic mice.

  1990cited by this paper
• The effects of MHC gene dosage and allelic variation on T cell receptor selection.

  1990cited by this paper
• Developmental biology of T cells in T cell-receptor transgenic mice.

  1990cited by this paper
• Role of self-peptides in positively selecting the T-cell repertoire

  1990cited by this paper
• Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs.

  1990cited by this paper
• CD8 is required during positive selection of CD4-/CD8+ T cells

  1990cited by this paper
• Developmental biology of T cells in T cell-receptor transgenic mice.

  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
• Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

  1988cited by this paper
• The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1984cited by this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2003cites this paper
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