Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Infection and Immunity

• Publication date

  2017-04-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.00177-17PMID 28438975PMCID PMC5478954
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neutrophils

  2019cited by this paper
• Evasion of Neutrophil Killing by Staphylococcus aureus

  2016cited by this paper
• Galectin-3 in Renal Pathology: More Than Just an Innocent Bystander?

  2016cited by this paper
• Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer.

  2014cited by this paper
• Microbe–Host Interactions are Positively and Negatively Regulated by Galectin–Glycan Interactions

  2014cited by this paper
• Surface proteins of Staphylococcus aureus play an important role in experimental skin infection

  2014cited by this paper
• Measurement of respiratory burst products, released or retained, during activation of professional phagocytes.

  2014cited by this paper
• Staphylokinase promotes the establishment of Staphylococcus aureus skin infections while decreasing disease severity.

  2013cited by this paper
• Pharmacological Inhibition of Platelet-Tumor Cell Cross-Talk Prevents Platelet-Induced Overexpression of Cyclooxygenase-2 in HT29 Human Colon Carcinoma Cells

  2013cited by this paper
• Staphylococcal Proteases Aid in Evasion of the Human Complement System

  2013cited by this paper
• Staphopains Modulate Staphylococcus aureus Biofilm Integrity

  2013cited by this paper
• Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers

  2013cited by this paper
• Galectin-3 Facilitates Neutrophil Recruitment as an Innate Immune Response to a Parasitic Protozoa Cutaneous Infection

  2013cited by this paper
• Binding of Transmembrane Mucins to Galectin-3 Limits Herpesvirus 1 Infection of Human Corneal Keratinocytes

  2013cited by this paper
• Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability

  2012cited by this paper
• Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis

  2012cited by this paper
• Galectin‐3 binds Neisseria meningitidis and increases interaction with phagocytic cells

  2012influential reference
• Galectins in acute and chronic inflammation

  2012cited by this paper
• Staphylococcal proteases aid evasion of human complement system

  2012cited by this paper
• Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.

  2012cited by this paper
• Staphylococcus aureus Metalloprotease Aureolysin Cleaves Complement C3 To Mediate Immune Evasion

  2011cited by this paper
• Galectin-3 and the skin.

  2011cited by this paper
• Matrilysin‐1 (MMP7) cleaves galectin‐3 and inhibits wound healing in intestinal epithelial cells

  2011cited by this paper
• Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its cognate Staphostatin, SspC

  2010cited by this paper
• Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response

  2009cited by this paper
• Roles of galectins in infection

  2009cited by this paper
• Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages

  2009cited by this paper
• Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils.

  2008cited by this paper
• A New Pathway of Staphylococcal Pathogenesis: Apoptosis-Like Death Induced by Staphopain B in Human Neutrophils and Monocytes

  2008cited by this paper
• Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N‐terminal fungalysin‐thermolysin‐propeptide domain

  2008cited by this paper
• Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function.

  2008influential reference
• Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.

  2008cited by this paper
• Role of Galectin-3 in Leukocyte Recruitment in a Murine Model of Lung Infection by Streptococcus pneumoniae1

  2008cited by this paper
• The epidemiology of and risk factors for invasive Staphylococcus aureus infections in western Sweden

  2007cited by this paper
• Activation of the SspA Serine Protease Zymogen of Staphylococcus aureus Proceeds through Unique Variations of a Trypsinogen-like Mechanism and Is Dependent on Both Autocatalytic and Metalloprotease-specific Processing*

  2007cited by this paper
• Galectin‐3 interacts with naïve and primed neutrophils, inducing innate immune responses

  2005cited by this paper
• Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection.

  2005cited by this paper
• Immune evasion by staphylococci

  2005cited by this paper
• Human Galectin-3 Promotes Trypanosoma cruzi Adhesion to Human Coronary Artery Smooth Muscle Cells

  2004cited by this paper
• Simulation of a 50GeV PWFA Stage

  2004cited by this paper
• The role and regulation of the extracellular proteases of Staphylococcus aureus.

  2004cited by this paper
• Impact of staphylococcal protease expression on the outcome of infectious arthritis.

  2004cited by this paper
• Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases

  2003cited by this paper
• Specific Recognition and Cleavage of Galectin-3 byLeishmania major through Species-specific Polygalactose Epitope*

  2002cited by this paper
• Extracellular Proteases of Staphylococcus spp.

  2002influential reference
• Role of Galectin-3 as an Adhesion Molecule for Neutrophil Extravasation During Streptococcal Pneumonia1

  2002cited by this paper
• σB Modulates Virulence Determinant Expression and Stress Resistance: Characterization of a Functional rsbU Strain Derived from Staphylococcus aureus 8325-4

  2002cited by this paper
• Variation in Extracellular Protease Production among Clinical Isolates of Staphylococcus aureus Due to Different Levels of Expression of the Protease Repressor sarA

  2002cited by this paper
• Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999.

  2001cited by this paper
• Description of Staphylococcus Serine Protease (ssp) Operon in Staphylococcus aureus and Nonpolar Inactivation of sspA-Encoded Serine Protease

  2001cited by this paper
• Molecular Cloning and Biochemical Characterisation of Proteases from Staphylococcus epidermidis

  2001influential reference
• Embryonic implantation in galectin 1/galectin 3 double mutant mice

  1998cited by this paper
• Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils.

  1998cited by this paper
• Staphylococcus aureus genetic loci impacting growth and survival in multiple infection environments

  1998cited by this paper
• Introduction to galectins

  1997cited by this paper
• Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages.

  1995cited by this paper
• A human lectin, galectin-3 (epsilon bp/Mac-2), stimulates superoxide production by neutrophils.

  1995influential reference
• Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.

  1994cited by this paper
• L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity.

  1993cited by this paper
• Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase.

  1993cited by this paper
• Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin.

  1992cited by this paper
• The inactivation of human plasma alpha 1-proteinase inhibitor by proteinases from Staphylococcus aureus.

  1986cited by this paper
• Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

  1968cited by this paper

• Mycobacterial phthiocerol dimycocerosate induces Galectin-3 upregulation to impair proinflammatory responses and favor immune evasion.

  2025cites this paper
• Staphylococcus aureus Biofilm-Associated Infections: Have We Found a Clinically Relevant Target?

  2025cites this paper
• Protein profiling and immunoinformatic analysis of the secretome of a metal-resistant environmental isolate Pseudomonas aeruginosa S-8

  2024cites this paper
• Impact of extracellular enzymes on Staphylococcus aureus host tissue adaptation and infection

  2024influential citation
• Staphylococcus aureus Proteases: Orchestrators of Skin Inflammation

  2024cites this paper
• TLR2-ERK signaling pathway regulates expression of galectin-3 in a murine model of OVA-induced allergic airway inflammation.

  2024cites this paper
• Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils

  2023cites this paper
• Understanding mechanisms of virulence in MRSA: implications for antivirulence treatment strategies

  2023cites this paper
• Exploring the macromolecules for secretory pathway in cancer disease.

  2023cites this paper
• An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin

  2022cites this paper
• Comparative secretome analysis of Staphylococcus aureus strains with different within-herd intramammary infection prevalence

  2022cites this paper
• Screening transcriptional connections in Staphylococcus aureus using high-throughput transduction of bioluminescent reporter plasmids.

  2022cites this paper
• Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome

  2022cites this paper
• Staphylococcus aureus Responds to Physiologically Relevant Temperature Changes by Altering Its Global Transcript and Protein Profile

  2021cites this paper
• Secretory Proteases of the Human Skin Microbiome

  2021cites this paper
• The Influence of Microbiome Dysbiosis and Bacterial Biofilms on Epidermal Barrier Function in Atopic Dermatitis—An Update

  2021cites this paper
• Insight into the human pathodegradome of the V8 protease from Staphylococcus aureus

  2021cites this paper
• Mycobacterial Phthiocerol Dimycocerosate Induces Galectin-3 Upregulation to Impair Proinflammatory Responses and Favor Immune Evasion in vivo

  2020cites this paper
• SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1

  2020cites this paper
• Characterization and functional study of Galectin3 from Japanese flounder (Paralichthys olivaceus).

  2020cites this paper
• Trypanosoma cruzi cleaves galectin‐3 N‐terminal domain to suppress its innate microbicidal activity

  2020cites this paper
• The Sweet-Side of Leukocytes: Galectins as Master Regulators of Neutrophil Function

  2019cites this paper
• Biomedicine & Pharmacotherapy

  2018cites this paper
• Lack of Receptor for Advanced Glycation End Products Leads to Less Severe Staphylococcal Skin Infection but More Skin Abscesses and Prolonged Wound Healing

  2018cites this paper
• Interaction of host and Staphylococcus aureus protease-system regulates virulence and pathogenicity

  2018cites this paper
• The expression and function of galectins in skin physiology and pathology

  2018cites this paper
• Cathepsins: Proteases that are vital for survival but can also be fatal

  2018cites this paper
• Biomedicine & Pharmacotherapy

  2018cites this paper
• The Role of Collectins and Galectins in Lung Innate Immune Defense

  2018cites this paper