Divalent cations suppress 3',5'-adenosine monophosphate accumulation by stimulating a pertussis toxin-sensitive guanine nucleotide-binding protein in cultured bovine parathyroid cells.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Endocrinology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1210/ENDO-124-1-233PMID 2462488
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Secretory control in normal and abnormal parathyroid tissue.

  1987cited by this paper
• High extracellular Ca2+ and Mg2+ stimulate accumulation of inositol phosphates in bovine parathyroid cells

  1987cited by this paper
• Effects of extracellular calcium and magnesium on cytosolic calcium concentration in fura‐2‐loaded bovine parathyroid cells

  1987cited by this paper
• Prostaglandin F2 alpha and alpha-adrenergic agonists regulate parathyroid cell function via the inhibitory guanine nucleotide regulatory protein.

  1986cited by this paper
• Cytosolic Ca2+ and the regulation of secretion in parathyroid cells

  1986cited by this paper
• Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein.

  1986cited by this paper
• Role of cytosolic calcium in the control of cAMP content by calcium in bovine parathyroid cells.

  1986cited by this paper
• Prostaglandin F2α and α-Adrenergic Agonists Regulate Parathyroid Cell Function via the Inhibitory Guanine Nucleotide Regulatory Protein

  1986cited by this paper
• Calcium-controlled secretion is effected through a guanine nucleotide regulatory protein in parathyroid cells.

  1986cited by this paper
• Regulation of parathyroid hormone release and cytosolic calcium by extracellular calcium in dispersed and cultured bovine and pathological human parathyroid cells.

  1985cited by this paper
• Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands.

  1985cited by this paper
• Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

  1984cited by this paper
• Extracellular calcium potentiates the inhibitory effects of magnesium on parathyroid function in dispersed bovine parathyroid cells.

  1984cited by this paper
• Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

  1984cited by this paper
• Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

  1984cited by this paper
• Calmodulin-like activity and calcium-dependent phosphodiesterase in purified cells of the rat zona glomerulosa and zona fasciculata.

  1983cited by this paper
• Depolarizing response of rat parathyroid cells to divalent cations

  1983cited by this paper
• Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells.

  1983cited by this paper
• Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells.

  1983cited by this paper
• Regulation of parathyroid hormone secretion in vitro by divalent cations and cellular metabolism.

  1982cited by this paper
• Adenylate cyclase activity in human parathyroid tissues: reduced sensitivity to suppression by calcium in parathyroid adenomas as compared with normal glands form normocalcemic subjects or noninvolved glands from hyperparathyroid subjects.

  1981cited by this paper
• Calmodulin in dispersed human parathyroid cells.

  1981cited by this paper
• Calcium-regulated phosphodiesterase in bovine parathyroid cells.

  1980cited by this paper
• Effects of the calcium ionophore A23187 on dispersed bovine parathyroid cells.

  1980cited by this paper
• Prostaglandin F2α Inhibits 3',5'-Adenosine Monophosphate Accumulation and Parathyroid Hormone Release from Dispersed Bovine Parathyroid Cells

  1979cited by this paper
• Prostaglandin F2alpha inhibits 3',3'-adenosine monophosphate accumulation and parathyroid hormone release from dispersed bovine parathyroid cells.

  1979cited by this paper
• alpha-Adrenergic inhibition of adenosine 3',5'-monophosphate accumulation and parathyroid hormone release from dispersed bovine parathyroid cells.

  1978cited by this paper
• Relationship of intracellular 3',5'-adenosine monophosphate accumulation to parathyroid hormone release from dispersed bovine parathyroid cells.

  1978cited by this paper
• Multiple cyclic nucleotide phosphodiesterase activities from rat brain.

  1971cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Activation profile of the Atlantic salmon (Salmo salar) calcium-sensing receptor (Casr) by selected L-amino acids

  2025cites this paper
• Calcium-sensing receptor in GtoPdb v.2025.3

  2025cites this paper
• Calcium-sensing receptor in GtoPdb v.2023.1

  2023cites this paper
• Calcium-sensing receptor in GtoPdb v.2021.3

  2021cites this paper
• Calcium-sensing receptor signaling: it’s all about multiplicity

  2020cites this paper
• Biology of the extracellular calcium-sensing receptor

  2020cites this paper
• Calcium-sensing receptor (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database

  2020cites this paper
• International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function

  2020cites this paper
• Calcium-sensing receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Discovery and Development of Calcimimetic and Calcilytic Compounds.

  2018cites this paper
• A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making.

  2018cites this paper
• Calcimimetic acts on enteric neuronal CaSR to reverse cholera toxin-induced intestinal electrolyte secretion

  2018cites this paper
• The Different Facets of Extracellular Calcium Sensors: Old and New Concepts in Calcium-Sensing Receptor Signalling and Pharmacology

  2018cites this paper
• Signal crosstalk between calcium-sensing and prostanoid receptors and its role in parathyroid hormone secretion

  2018cites this paper
• The Calcium-Sensing Receptor and the Parathyroid: Past, Present, Future

  2016cites this paper
• Protein kinase involvement in wild-type and mutant calcium-sensing receptor signalling

  2016cites this paper
• CALCIUM REGULATION OF CELL-CELL COMMUNICATION AND EXTRACELLULAR SIGNALING

  2016cites this paper
• Interplay between CaSR and PTH1R signaling in skeletal development and osteoanabolism.

  2016cites this paper
• Control of Parathyroid Hormone Secretion by its Key Physiological Regulators

  2015cites this paper
• Control of Parathyroid Hormone Secretion by Extracellular Ca2

  2015cites this paper
• Calcium Sensing Receptors: Coordinators of Mineral Metabolism and Therapeutic Targets for Metabolic Bone Disorders

  2014cites this paper
• Engendering biased signalling from the calcium‐sensing receptor for the pharmacotherapy of diverse disorders

  2014cites this paper
• The Physiological Basis of Metabolic Bone Disease

  2014cites this paper
• Calcium-sensing receptor 20 years later.

  2014cites this paper
• Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptor.

  2013cites this paper
• Calcium supplementation increases circulating cholesterol by reducing its catabolism via GPER and TRPC1-dependent pathway in estrogen deficient women.

  2013cites this paper
• Best Practice & Research Clinical Endocrinology & Metabolism

  2013cites this paper
• Gastric acid, calcium absorption, and their impact on bone health.

  2013influential citation
• Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways.

  2013cites this paper
• New concepts in calcium‐sensing receptor pharmacology and signalling

  2012cites this paper
• Parathyroid Hormone and Calcium Homeostasis

  2012cites this paper
• The calcium-sensing receptor: a molecular perspective.

  2011cites this paper
• Differential Modulation of Intracellular Ca2+ Responses Associated with Calcium-Sensing Receptor Activation in Renal Collecting Duct Cells

  2011cites this paper
• Discovery of a Calcimimetic with Differential Effects on Parathyroid Hormone and Calcitonin Secretion

  2011cites this paper
• Blockade of Receptor-Activated Gi Signaling in Osteoblasts In Vivo Leads to Site-Specific Increases in Cortical and Cancellous Bone Formation

  2010cites this paper
• Thick ascending limb: the Na+:K+:2Cl− co-transporter, NKCC2, and the calcium-sensing receptor, CaSR

  2009cites this paper
• Calcium-sensing receptor and associated diseases.

  2009cites this paper
• [Extracellular calcium sensing under normal and pathological conditions].

  2009cites this paper
• Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor.

  2009cites this paper
• Az extracelluláris kalciumkoncentráció érzékelése egészséges és kóros állapotokban

  2009cites this paper
• Phosphorus Homeostasis and Related Disorders

  2008cites this paper
• Biology of the Extracellular Ca2+-Sensing Receptor

  2008cites this paper
• Parathyroid-specific interaction of the calcium-sensing receptor and G alpha q.

  2008cites this paper
• Destabilization of parathyroid hormone mRNA by extracellular Ca2+ and the calcimimetic R-568 in parathyroid cells: role of cytosolic Ca and requirement for gene transcription.

  2008influential citation
• Proteins associated with the intracellular signalling tail of the calcium-sensing receptor and their impact on receptor function

  2008cites this paper
• Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.

  2007cites this paper
• G protein-coupled, extracellular Ca2+ (Cao2+)-sensing receptor enables Cao2+ to function as a versatile extracellular first messenger

  2007cites this paper
• Calcium sensing receptors and calcium oscillations: calcium as a first messenger.

  2006cites this paper
• Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis.

  2006cites this paper
• The calcium-sensing receptor in hereditary disordersof calcium homeostasis

  2006cites this paper
• Misconceptions About Calcimimetics

  2006cites this paper
• The calcium-sensing receptor.

  2005cites this paper
• Termination of cAMP signals by Ca 2 (cid:1) and G (cid:1) i via extracellular Ca 2 (cid:1) sensors: a link to intracellular Ca 2 (cid:1) oscillations

  2005cites this paper
• Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations.

  2005cites this paper
• Mammalian G proteins and their cell type specific functions.

  2005cites this paper
• Termination of cAMP signals by Ca2+ and Gαi via extracellular Ca2+ sensors

  2005cites this paper
• Efeito do cálcio extracelular na osteogénese através da regulação do calcium sensing receptor

  2005cites this paper
• Extracellular Ca2+-sensing receptors--an overview.

  2004cites this paper
• Calcium sensing by endocrine cells

  2004cites this paper
• The role of extracellular calcium in the regulation of intracellular calcium and cell function (II). Some answers and more questions.

  2004cites this paper
• Calcium receptor-mediated intracellular signalling.

  2004cites this paper
• Disorders of the Endocrine System

  2004cites this paper
• Extracellular calcium acts as a “third messenger” to regulate enzyme and alkaline secretion

  2004cites this paper
• Chapter 18 – Disorders of the Endocrine System

  2004cites this paper
• Calcium‐Sensing Receptor

  2003cites this paper
• An Overview of Extracellular Calcium Homeostasis and the Roles of the CaR in Parathyroid and C-cells

  2003cites this paper
• Calcium Receptor-mediated Signaling

  2003cites this paper
• Is the calcium receptor a molecular target for the actions of strontium on bone?

  2003cites this paper
• Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells.

  2003cites this paper
• Human calcium-sensing receptor can be suppressed by antisense sequences.

  2003cites this paper
• Calcium-Sensing Receptor

  2003cites this paper
• Signaling of the human calcium-sensing receptor expressed in HEK293-cells is modulated by protein kinases A and C.

  2003cites this paper
• Calcium Receptors as Novel Drug Targets

  2002cites this paper
• CHAPTER 8 – Receptors and Signaling for Calcium Ions

  2001cites this paper
• Extracellular calcium sensing and extracellular calcium signaling.

  2001cites this paper
• Extracellular Calcium-sensing Receptor Is Expressed in Rat Hepatocytes

  2001cites this paper
• G protein-coupled extracellular Ca2+ (Ca2+o)-sensing receptor (CaR): roles in cell signaling and control of diverse cellular functions.

  2000cites this paper
• Calcium‐sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia

  2000cites this paper
• Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase.

  2000cites this paper
• Disorders Resulting from Inactivating or Activating Mutations in the Ca2+ 0-Sensing Receptor

  2000cites this paper
• Non-Ca2+-homeostatic functions of the extracellular Ca2+-sensing receptor (CaR) in endocrine tissues.

  2000cites this paper
• Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo.

  2000cites this paper
• Decreased Responsiveness to Extracellular Ca2+ Owing to Abnormalities in the Ca2+o-Sensing Receptor

  1999cites this paper
• Parathyroid Hormone and Polyhormones: Production and Export

  1999cites this paper
• [The key to the calcium regulation and calcium metabolism: G protein coupled membrane calcium receptor].

  1999cites this paper
• G-protein-coupled, extracellular Ca(2+)-sensing receptor: a versatile regulator of diverse cellular functions.

  1999cites this paper
• Expression and signal transduction of calcium-sensing receptors in cartilage and bone.

  1999cites this paper
• Structure and function of the extracellular calcium-sensing receptor (Review).

  1999cites this paper
• Expression and Signal Transduction of Calcium-Sensing Receptors in Cartilage and Bone1.

  1999cites this paper
• Physiology and pathophysiology of the extracellular calcium-sensing receptor.

  1999cites this paper
• Disorders with Increased or Decreased Responsiveness to Extracellular Ca2+ Owing to Mutations in the Ca2+ o-Sensing Receptor

  1998cites this paper
• Mg2+/Ca2+sensing inhibits hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells.

  1998cites this paper
• Activating mutations of the Ca2+-sensing receptor.

  1998cites this paper
• The Calcium Receptor in Health and Disease

  1998cites this paper
• Coupling of Calcium Receptors to Inositol Phosphate and Cyclic AMP Generation in Mammalian Cells and Xenopus laevis Oocytes and Immunodetection of Receptor Protein by Region‐Specific Antipeptide Antisera

  1998cites this paper
• Mg2+/Ca2+ sensing inhibits hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells.

  1998cites this paper
• Functional Calcium-sensing Receptors in Rat Fibroblasts Are Required for Activation of SRC Kinase and Mitogen-activated Protein Kinase in Response to Extracellular Calcium*

  1998cites this paper
• Calcimimetics with potent and selective activity on the parathyroid calcium receptor.

  1998cites this paper
• The calcium-sensing receptor (CaR) permits Ca2+ to function as a versatile extracellular first messenger.

  1998cites this paper
• Co-expression of a Ca2+-inhibitable Adenylyl Cyclase and of a Ca2+-sensing Receptor in the Cortical Thick Ascending Limb Cell of the Rat Kidney

  1998cites this paper