Honokiol as a Radiosensitizing Agent for Colorectal Cancers

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Current Colorectal Cancer Reports

• Publication date

  2013-10-04

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11888-013-0191-4PMID 24307888PMCID PMC3844429
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model.

  2013cited by this paper
• Gastric stem cells and gastric cancer stem cells

  2013cited by this paper
• Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma

  2013cited by this paper
• Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

  2013cited by this paper
• Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP‐1

  2012cited by this paper
• Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia.

  2012cited by this paper
• TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells.

  2012cited by this paper
• Notch signaling and intestinal cancer.

  2012cited by this paper
• Effects of trichostatin A on HIF-1α and VEGF expression in human tongue squamous cell carcinoma cells in vitro.

  2012cited by this paper
• Differentiation pathways in carcinogenesis and in chemo- and radioresistance.

  2012cited by this paper
• Surgical Treatment of Patients with Lennox-Gastaut Syndrome Phenotype

  2012cited by this paper
• Novel biomarkers and therapeutic targets for optimizing the therapeutic management of melanomas.

  2012cited by this paper
• Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.

  2012cited by this paper
• γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells

  2012cited by this paper
• Cell division cycle 25 homolog c effects on low-dose hyper-radiosensitivity and induced radioresistance at elevated dosage in A549 cells

  2012cited by this paper
• Honokiol: a novel natural agent for cancer prevention and therapy.

  2012cited by this paper
• Inhibiting the aurora B kinase potently suppresses repopulation during fractionated irradiation of human lung cancer cell lines.

  2012cited by this paper
• Calpain/SHP-1 Interaction by Honokiol Dampening Peritoneal Dissemination of Gastric Cancer in nu/nu Mice

  2012cited by this paper
• Notch signaling in cancer stem cells.

  2012cited by this paper
• Notch inhibition suppresses nasopharyngeal carcinoma by depleting cancer stem-like side population cells.

  2012cited by this paper
• Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation.

  2012cited by this paper
• Cancer statistics, 2012

  2012cited by this paper
• Honokiol in Combination with Radiation Targets Notch Signaling to Inhibit Colon Cancer Stem Cells

  2012cited by this paper
• Targeting a cornerstone of radiation resistance: cancer stem cell.

  2012cited by this paper
• PI3K/AKT/mTOR Pathway in Angiogenesis

  2011cited by this paper
• Combination of pigment epithelium‐derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis

  2011cited by this paper
• Molecular portraits of intratumoral heterogeneity in human ovarian cancer.

  2011cited by this paper
• Honokiol radiosensitizes colorectal cancer cells: enhanced activity in cells with mismatch repair defects.

  2011cited by this paper
• Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission

  2011cited by this paper
• Inhibition of JAK2 Signaling by TG101209 Enhances Radiotherapy in Lung Cancer Models

  2011cited by this paper
• Suppression of the notch signaling pathway by γ-secretase inhibitor GSI inhibits human nasopharyngeal carcinoma cell proliferation.

  2011cited by this paper
• Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma*

  2011cited by this paper
• Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma.

  2011cited by this paper
• Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

  2010cited by this paper
• Long‐term results of a phase 2 study of neoadjuvant chemotherapy and radiotherapy in the management of high‐risk, high‐grade, soft tissue sarcomas of the extremities and body wall

  2010cited by this paper
• Cucurbitacin: Ancient Compound Shedding New Light on Cancer Treatment

  2010cited by this paper
• Radiation‐induced HIF‐1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells

  2009cited by this paper
• Differential Cellular Responses to Prolonged LDR-IR in MLH1-Proficient and MLH1-Deficient Colorectal Cancer HCT116 Cells

  2009cited by this paper
• Cyclooxygenase-2 in Cancer and Angiogenesis

  2009cited by this paper
• Overall Cdk activity modulates the DNA damage response in mammalian cells

  2009cited by this paper
• Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

  2009cited by this paper
• Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction

  2008cited by this paper
• Liposomal honokiol, a promising agent for treatment of cisplatin-resistant human ovarian cancer

  2008cited by this paper
• Enhancement of therapeutic effectiveness by combining liposomal honokiol with cisplatin in ovarian carcinoma

  2007cited by this paper
• The DNA damage response: ten years after.

  2007cited by this paper
• ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

  2007cited by this paper
• Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1alpha-mediated tumor apoptotic switch.

  2007cited by this paper
• Akt signaling and cancer: surviving but not moving on.

  2006cited by this paper
• Honokiol Potentiates Apoptosis, Suppresses Osteoclastogenesis, and Inhibits Invasion through Modulation of Nuclear Factor-κB Activation Pathway

  2006cited by this paper
• Differential mechanisms of radiosensitization by 2-deoxy-D-glucose in the monolayers and multicellular spheroids of a human glioma cell line

  2006cited by this paper
• Aberrant Stat3 signaling by interleukin-4 in malignant glioma cells: involvement of IL-13Ralpha2.

  2005cited by this paper
• The role of IL-6 and STAT3 in inflammation and cancer.

  2005cited by this paper
• Down-regulation of ATM Protein Sensitizes Human Prostate Cancer Cells to Radiation-induced Apoptosis*

  2005cited by this paper
• Effect of a standardized complex mixture derived from coal tar on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.

  2005cited by this paper
• Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

  2005cited by this paper
• The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.

  2004cited by this paper
• Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells.

  2003cited by this paper
• SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro.

  2003cited by this paper
• Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo*

  2003cited by this paper
• Radiation-induced cell cycle response in lymphocytes is not related to clinical side-effects in breast cancer patients.

  2003cited by this paper
• Vascular Endothelial Growth Factor Enhances Endothelial Cell Survival and Tumor Radioresistance

  2002cited by this paper
• Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.

  1994cited by this paper
• Molecular and Cellular Pathobiology Activated Notch1 Induces Lung Adenomas in Mice and Cooperates with Myc in the Generation of Lung Adenocarcinoma

  year unknowncited by this paper

• Exploring the versatile world of magnolias: urban landscape enhancement and metabolite applications in drug discovery and cosmetics

  2025cites this paper
• Multi-pathway therapeutics in colorectal cancer: Targeting EMT, CSCs, and non-apoptotic cell death for drug resistance reversal.

  2025cites this paper
• Management of adenocarcinoma with honokiol: progress so far and the way forward.

  2023cites this paper
• Pharmacological features, health benefits and clinical implications of honokiol

  2022influential citation
• Honokiol inhibits proliferation of colorectal cancer cells by targeting anoctamin 1/TMEM16A Ca2+‐activated Cl− channels

  2021cites this paper
• Honokiol: A Review of Its Anticancer Potential and Mechanisms

  2019cites this paper
• Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets.

  2019cites this paper
• Gene Silencing of Human Sertoli Cells Utilizing Small Interfering RNAs.

  2018cites this paper
• Honokiol: An anticancer lignan.

  2018cites this paper
• Sertoli Cells

  2018cites this paper
• Honokiol targets mitochondria to halt cancer progression and metastasis.

  2016cites this paper