Analysis of highly polar metabolites in human plasma by ultra-performance hydrophilic interaction liquid chromatography coupled with quadrupole-time of flight mass spectrometry.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Analytica Chimica Acta

• Publication date

  2009-09-14

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.aca.2009.01.054PMID 19720166
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fast sample preparation and liquid chromatography-tandem mass spectrometry method for assaying cell lysate acetylcholine.

  2008cited by this paper
• Separation efficiencies in hydrophilic interaction chromatography.

  2008cited by this paper
• A metabonomic study of strain- and age-related differences in the Zucker rat.

  2007cited by this paper
• Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning 1H NMR spectroscopy in conjunction with multivariate data analysis.

  2007cited by this paper
• Hydrophilic interaction chromatography for mass spectrometric metabonomic studies of urine.

  2007cited by this paper
• Hydrophilic interaction chromatography coupled to nuclear magnetic resonance spectroscopy and mass spectroscopy--a new approach for the separation and identification of extremely polar analytes in bodyfluids.

  2007cited by this paper
• A comprehensive urinary metabolomic approach for identifying kidney cancerr.

  2007cited by this paper
• Metabonomics in pharmaceutical discovery and development.

  2007cited by this paper
• Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

  2006cited by this paper
• Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry.

  2006cited by this paper
• Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS).

  2006cited by this paper
• Impact of analytical bias in metabonomic studies of human blood serum and plasma.

  2006cited by this paper
• Metabolic fingerprinting of rat urine by LC/MS Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry.

  2005cited by this paper
• Metabolic fingerprinting of rat urine by LC/MS Part 2. Data pretreatment methods for handling of complex data.

  2005cited by this paper
• Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis.

  2005cited by this paper
• A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice.

  2005cited by this paper
• Retention behavior of small polar compounds on polar stationary phases in hydrophilic interaction chromatography.

  2005cited by this paper
• HPLC-MS-based methods for the study of metabonomics.

  2005cited by this paper
• Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

  2004cited by this paper
• Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles.

  2004cited by this paper
• Mass spectrometry techniques for qualitative and quantitative analysis of biomarkers.

  2004cited by this paper
• Protein precipitation for the analysis of a drug cocktail in plasma by LC-ESI-MS.

  2004cited by this paper
• Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry.

  2003cited by this paper
• Application of proteomic technologies in the drug development process.

  2003cited by this paper
• Metabonomics: a platform for studying drug toxicity and gene function

  2002cited by this paper
• 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data.

  1999cited by this paper
• Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds.

  1990cited by this paper

• A Rapid Reversed-Phase LC-MS Method for Polar Metabolite Profiling

  2026cites this paper
• Reaction-Based Fluorescence Assays for the Determination of Food Trimethylamine Oxide.

  2024cites this paper
• In Silico and Chromatographic Methods for Analysis of Biotransformation of Prospective Neuroprotective Pyrrole-Based Hydrazone in Isolated Rat Hepatocytes

  2024influential citation
• Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound

  2023cites this paper
• Influence of Age, Sex, and Diet on the Human Fecal Metabolome Investigated by 1H NMR Spectroscopy.

  2021cites this paper
• A metabolomics approach to investigate the proceedings of mitochondrial dysfunction in rats from prediabetes to diabetes

  2021cites this paper
• High-throughput LC-MS quantitation of cell culture metabolites.

  2019cites this paper
• Hydrophilic Interaction Chromatography

  2019cites this paper
• A HILIC-UHPLC-MS/MS untargeted urinary metabonomics combined with quantitative analysis of five polar biomarkers on osteoporosis rats after oral administration of Gushudan.

  2018cites this paper
• A novel liquid chromatography/mass spectrometry method for determination of neurotransmitters in brain tissue: Application to human tauopathies.

  2018cites this paper
• Advances in Hydrophilic Interaction Liquid Chromatography

  2017cites this paper
• A plasma metabonomic analysis on potential biomarker in pyrexia induced by three methods using ultra high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry.

  2017cites this paper
• Hydrophilic Interaction Liquid Chromatography/Mass Spectrometry: An Attractive and Prospective Method for the Quantitative Bioanalysis in Drug Metabolism.

  2016cites this paper
• Metabolite identification and pharmacokinetic study of Lamiophlomis rotata in rats

  2016cites this paper
• Analysis of human plasma metabolites across different liquid chromatography/mass spectrometry platforms: Cross-platform transferable chemical signatures.

  2016cites this paper
• Yuanhuapine-induced intestinal and hepatotoxicity were correlated with disturbance of amino acids, lipids, carbohydrate metabolism and gut microflora function: A rat urine metabonomic study.

  2016cites this paper
• HILIC-MS for metabolomics: An attractive and complementary approach to RPLC-MS.

  2016cites this paper
• Stable isotope dilution HILIC-MS/MS method for accurate quantification of glutamic acid, glutamine, pyroglutamic acid, GABA and theanine in mouse brain tissues.

  2016cites this paper
• HILIC-UPLC-MS/MS combined with hierarchical clustering analysis to rapidly analyze and evaluate nucleobases and nucleosides in Ginkgo biloba leaves.

  2015cites this paper
• UPLC-Q-TOF/MS-based screening and identification of the main flavonoids and their metabolites in rat bile, urine and feces after oral administration of Scutellaria baicalensis extract.

  2015cites this paper
• A pH and solvent optimized reverse-phase ion-paring-LC–MS/MS method that leverages multiple scan-types for targeted absolute quantification of intracellular metabolites

  2015cites this paper
• Fast Swinnex filtration (FSF): a fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media

  2015cites this paper
• Comparison of capillary electrophoresis-mass spectrometry and hydrophilic interaction chromatography-mass spectrometry for anionic metabolic profiling of urine.

  2015cites this paper
• Comprehensive analysis of fatty alcohol ethoxylates by ultra high pressure hydrophilic interaction chromatography coupled with ion mobility spectrometry mass spectrometry using a custom-designed sub-2 μm column.

  2015cites this paper
• A rapid and simple method for the simultaneous determination of four endogenous monoamine neurotransmitters in rat brain using hydrophilic interaction liquid chromatography coupled with atmospheric-pressure chemical ionization tandem mass spectrometry.

  2015cites this paper
• UPLC-PDA-TOF/MS coupled with multivariate statistical analysis to rapidly analyze and evaluate Ginkgo biloba leaves from different origin.

  2014cites this paper
• Targeted metabolomics in cultured cells and tissues by mass spectrometry: method development and validation.

  2014cites this paper
• Rapid determination of amino acids in fruits of Ziziphus jujuba by hydrophilic interaction ultra-high-performance liquid chromatography coupled with triple-quadrupole mass spectrometry.

  2013cites this paper
• Hydrophilic interaction ultra-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry for highly rapid and sensitive analysis of underivatized amino acids in functional foods

  2013cites this paper
• Direct determination of underivatized amino acids from Ginkgo biloba leaves by using hydrophilic interaction ultra high performance liquid chromatography coupled with triple quadrupole mass spectrometry.

  2013cites this paper
• Metabolomics and its potential in drug development.

  2013cites this paper
• Hydrophilic interaction ultra-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry for highly rapid and sensitive analysis of underivatized amino acids in functional foods

  2013cites this paper
• Comparative analysis of nucleosides and nucleobases from different sections of Elaphuri Davidiani Cornu and Cervi Cornu by UHPLC-MS/MS.

  2013cites this paper
• Hydrophilic interaction ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry for determination of nucleotides, nucleosides and nucleobases in Ziziphus plants.

  2013cites this paper
• Metabonomics analysis of urine and plasma from rats given long-term and low-dose dimethoate by ultra-performance liquid chromatography-mass spectrometry.

  2012cites this paper
• Semi-targeted metabolomic approaches to validate potential markers of health for micronutrients: analytical perspectives

  2012cites this paper
• Retention prediction of a set of amino acids under gradient elution conditions in hydrophilic interaction liquid chromatography.

  2012cites this paper
• Hydrophilic interaction chromatography-electrospray ionization tandem mass spectrometric analysis of anastrozole in human plasma and its application to a pharmacokinetic study.

  2012cites this paper
• Metabolomics in food analysis: application to the control of forbidden substances.

  2012cites this paper
• Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatography-tandem mass spectrometry.

  2012cites this paper
• LC-MS metabolomics of polar compounds.

  2012cites this paper
• Metabolomic study of plasma from female mink (Neovison vison) with low and high residual feed intake during restrictive and ad libitum feeding.

  2012cites this paper
• Targeted mass spectrometry-based metabolomic profiling through multiple reaction monitoring of liver and other biological matrices.

  2012cites this paper
• Ultra performance liquid chromatography coupled with electrospray and atmospheric pressure chemical ionization (ESCi)-quadrupole time-of-flight mass spectrometry with novel mass spectrometry(Elevated Energy) (MS(E)) data collection technique: determination and pharmacokinetics, tissue distribution a

  2012cites this paper
• Hydrophilic interaction ultra performance liquid chromatography retention prediction under gradient elution

  2012cites this paper
• Metabolomic investigations into human apocrine sweat secretions

  2012cites this paper
• PHARMACOKINETICS, BIOAVAILABILITY, AND METABOLISM OF 2,3,5,4′-TETRAHYDROXYSTILBENE-2-O-β-D-GLUCOSIDE IN RATS BY ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY–QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-ULTRAVIOLET DETECTION

  2012cites this paper
• Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole–time of flight mass spectrometry (UPLC–Q–ToF-MS)

  2011cites this paper
• Mass spectrometry-based metabolomics applied to the chemical safety of food

  2011cites this paper
• Comparison of the determination of folate vitamers with hydrophilic interaction chromatography and reversed phase chromatography

  2011cites this paper
• LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery.

  2011cites this paper
• Advantages of tandem LC-MS for the rapid assessment of tissue-specific metabolic complexity using a pentafluorophenylpropyl stationary phase.

  2011cites this paper
• UHPLC-TOFMS coupled with chemometric method as a powerful technique for rapid exploring of differentiating components between two Ziziphus species.

  2011cites this paper
• Stationary and mobile phases in hydrophilic interaction chromatography: a review.

  2011cites this paper
• Metabonomic Study of Lung Cancer and the Effects of Radiotherapy on Lung Cancer Patients: Analysis of Highly Polar Metabolites by Ultraperformance HILIC Coupled with Q-TOF MS

  2011cites this paper
• Lysophosphatidylcholine profiling of plasma: discrimination of isomers and discovery of lung cancer biomarkers

  2010cites this paper
• Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of adefovir in human plasma and its application to a pharmacokinetic study.

  2010cites this paper
• Ultrahigh performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites.

  2010cites this paper
• Development and validation of a hydrophilic interaction liquid chromatographic method for determination of aromatic amines in environmental water.

  2010cites this paper
• Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies.

  2010cites this paper
• A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

  2010cites this paper