DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Cell

• Publication date

  1985-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0092-8674(85)90358-7PMID 2985272
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fusion proteins in retroviral transformation.

  1985cited by this paper
• Regulation of heat shock protein 70 gene expression by c-myc

  1984cited by this paper
• Serine- and threonine-specific protein kinase activities of purified gag–mil and gag–raf proteins

  1984cited by this paper
• Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by chicken c-myb gene.

  1984cited by this paper
• Inhibition of DNA binding of purified p55v‐myc in vitro by antibodies against bacterially expressed myc protein and a synthetic peptide.

  1984cited by this paper
• Avian myeloblastosis virus and E26 virus oncogene products are nuclear proteins.

  1984cited by this paper
• Properties of the myc-gene product: nuclear association, inhibition of transcription and activation in stimulated lymphocytes.

  1984cited by this paper
• Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by the chicken c-myb gene

  1984cited by this paper
• Tripartite structure of the avian erythroblastosis virus E26 transforming gene

  1983cited by this paper
• Identification of the leukemogenic protein of avian myeloblastosis virus and of its normal cellular homologue.

  1983cited by this paper
• The transforming protein of the MC29‐related virus CMII is a nuclear DNA‐binding protein whereas MH2 codes for a cytoplasmic RNA‐DNA binding polyprotein.

  1983cited by this paper
• Decreased DNA-binding ability of purified transformation-specific proteins from deletion mutants of the acute avian leukemia virus MC29.

  1983cited by this paper
• Organization of chicken DNA sequences homologous to the transforming gene of avian myeloblastosis virus. II. Isolation and characterization of lambda proto-amv DNA recombinant clones from a library of leukemic chicken DNA

  1983cited by this paper
• The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb.

  1983cited by this paper
• A putative second cell-derived oncogene of the avian leukaemia retrovirus E26

  1983cited by this paper
• Characterization of the hemopoietic target cells for the avian leukemia virus E26.

  1983cited by this paper
• Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus

  1982cited by this paper
• Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene.

  1982cited by this paper
• Myeloblasts transformed by the avian acute leukemia virus E26 are hormone‐dependent for growth and for the expression of a putative myb‐containing protein, p135 E26.

  1982cited by this paper
• Association of gag‐myc proteins from avian myelocytomatosis virus wild‐type and mutants with chromatin.

  1982cited by this paper
• Nuclear location of the putative transforming protein of avian myelocytomatosis virus.

  1982cited by this paper
• Nucleotide sequence of the transforming gene of avian myeloblastosis virus.

  1982cited by this paper
• Acute leukemia viruses E26 and avian myeloblastosis virus have related transformation-specific RNA sequences but different genetic structures, gene products, and oncogenic properties.

  1982cited by this paper
• Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene.

  1982cited by this paper
• Isolation of monoclonal antibodies against avian oncornaviral protein p19

  1981cited by this paper
• Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail.

  1981cited by this paper
• Plasmid vectors for high-efficiency expression controlled by the PL promoter of coliphage lambda.

  1981cited by this paper
• Proposal for Naming Host Cell-Derived Inserts in Retrovirus Genomes

  1981cited by this paper
• The genome and the intracellular RNAs of avian myeloblastosis virus.

  1981cited by this paper
• Size and genetic content of virus-specific RNA in myeloblasts transformed by avian myeloblastosis virus (AMV).

  1981cited by this paper
• Genetic structure of avian myeloblastosis virus, released from transformed myeloblasts as a defective virus particle.

  1980cited by this paper
• Cellular sequences are present in the presumptive avian myeloblastosis virus genome.

  1980cited by this paper
• Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation

  1979cited by this paper
• Transforming capacities and defectiveness of avian leukemia viruses OK10 and E 26.

  1979cited by this paper
• Avian leukemia viruses: interaction with their target cells in vivo and in vitro.

  1978cited by this paper
• Differential expression of Rous Sarcoma virus-specific transformation parameters in enucleated cells.

  1978cited by this paper
• A rapid, novel method for the solid-phase derivatization of IgG antibodies for immune-affinity chromatography.

  1978cited by this paper
• Leukemic transformation with avian myeloblastosis virus: present status.

  1975cited by this paper

• Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer

  2022cites this paper
• Translocations involving ETS family proteins in human cancer.

  2018cites this paper
• Aberrant expression of ETS1 and ETS2 proteins in cancer.

  2018cites this paper
• Lines Oligodeoxynucleotides in Transformed Neuroectodermal Cell Antisense RNA and myb Inhibition of Proliferation by c-Updated Version

  2006cites this paper
• ANTISENSE OLIGONUCLEOTIDES

  2005cites this paper
• TARGET GENES OF V-MYB AND C-MYB

  2004cites this paper
• Interaction of the oncogene protein myc with specific DNA fragments

  2004cites this paper
• myb Proto-Oncogene Product as a Transcriptional Regulator

  1997cites this paper
• The Myb oncoprotein: regulating a regulator.

  1996cites this paper
• Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line

  1996cites this paper
• Identification of an inducible regulator of c-myb expression during T-cell activation

  1996cites this paper
• Binding site analysis of c-Myb: screening of potential binding sites by using the mutation matrix derived from systematic binding affinity measurements.

  1996cites this paper
• v‐Myb DNA binding is required to block thrombocytic differentiation of Myb‐Ets‐transformed multipotent haematopoietic progenitors.

  1995cites this paper
• Myb binding sites mediate negative regulation of c-myb expression in T-cell lines.

  1995cites this paper
• The myb oncogene family of transcription factors: potent regulators of hematopoietic cell proliferation and differentiation.

  1994cites this paper
• Meeting report: antisense oligonucleotides.

  1994cites this paper
• Myb proteins talking to their DNA (review).

  1994cites this paper
• Presence of regulatory sequences within intron 4 of human and murine c-myb genes.

  1994cites this paper
• A spontaneous internal deletion of the c-myb protooncogene enhances transcriptional activation in bovine T lymphoma cells.

  1994cites this paper
• v-myb blocks granulocyte colony-stimulating factor-induced myeloid cell differentiation but not proliferation

  1993cites this paper
• Molecular astrology: the case of the Myb DNA binding domain.

  1993cites this paper
• Differential transcriptional activation by v-myb and c-myb in animal cells and Saccharomyces cerevisiae

  1993cites this paper
• Functional significance of c-myb expression in normal and leukemic hematopoiesis.

  1993cites this paper
• Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo

  1993cites this paper
• c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.

  1993cites this paper
• Methylation-sensitive DNA binding by v-myb and c-myb proteins.

  1993cites this paper
• The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum.

  1992cites this paper
• Production of v-Myb and c-Myb in insect cells infected with recombinant baculoviruses.

  1992cites this paper
• Definition of functional domains in P135gag-myb-ets and p48v-myb proteins required to maintain the response of neuroretina cells to basic fibroblast growth factor

  1992cites this paper
• Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors.

  1992cites this paper
• Protein truncation is not required for c-myb proto-oncogene activity in neuroretina cells

  1992cites this paper
• Inhibition of proliferation by c-myb antisense RNA and oligodeoxynucleotides in transformed neuroectodermal cell lines.

  1992cites this paper
• Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression.

  1992cites this paper
• The various domains of v-myb and v-ets oncogenes of E26 retrovirus contribute differently, but cooperatively, in transformation of hematopoietic lineages.

  1992cites this paper
• Functional antagonism between members of the myb family: B‐myb inhibits v‐myb‐induced gene activation.

  1992cites this paper
• The Jun family members, c-Jun and JunD, transactivate the human c-myb promoter via an Ap1-like element.

  1992cites this paper
• Molecular cloning, expression and in vitro functional characterization of Myb-related proteins in Xenopus.

  1992cites this paper
• Expression patterns of c-myb and of v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo.

  1992cites this paper
• Interaction of the Myb protein with specific DNA binding sites.

  1992cites this paper
• Retroviruses in Rodents

  1992cites this paper
• 8 – Erythroleukemia Cells

  1992cites this paper
• Production of v-Myb and c-Myb 1n insect cells infected with recombinant baculoviruses

  1992cites this paper
• Analysis of the v-myb structural components important for transactivation of gene expression.

  1991cites this paper
• Isolation and in vitro characterization of temperature-sensitive mutants of the bacteriophage f1 gene V protein.

  1991cites this paper
• Estrogen‐dependent alterations in differentiation state of myeloid cells caused by a v‐myb/estrogen receptor fusion protein.

  1991cites this paper
• Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb.

  1991cites this paper
• Transformation by carboxyl-deleted Myb reflects increased transactivating capacity and disruption of a negative regulatory domain.

  1991cites this paper
• v-myb and v-ets cooperate for the mitogenic stimulation of primary fibroblasts by avian E26 retrovirus

  1991cites this paper
• Protein truncation is required for the activation of the c-myb proto-oncogene.

  1991cites this paper
• Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses.

  1991cites this paper
• Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene

  1991cites this paper
• Two c-myb proteins differing by their aminotermini exhibit different transcriptional transactivation activities (yeast/reporter-effector system).

  1991cites this paper
• A myb gene required for leaf trichome differentiation in Arabidopsis is expressed in stipules.

  1991cites this paper
• Protein truncation is required for the activation of the c-myb proto-oncogene

  1991cites this paper
• Alteration of nuclear proto-oncogene expression by erythropoietin (Epo) in Epo-responsive murine cell lines.

  1991cites this paper
• Differential expression of the oncoproteins c-myc and c-myb in human lymphoproliferative disorders.

  1990cites this paper
• Characterization of the sequence‐specific interaction of mouse c‐myb protein with DNA.

  1990cites this paper
• Transcriptional down-regulation of c-myc expression by protein synthesis-dependent and -independent pathways in a human T lymphoblastic tumor cell line.

  1990cites this paper
• Characterization of the v-myb DNA binding domain.

  1990cites this paper
• New light on Myc and Myb. Part II. Myb.

  1990cites this paper
• trans activation of gene expression by v-myb

  1990cites this paper
• The myb oncogene.

  1990cites this paper
• The tryptophan cluster: a hypothetical structure of the DNA-binding domain of the myb protooncogene product.

  1990cites this paper
• Differentiation of mouse erythroleukemia cells enhanced by alternatively spliced c-myb mRNA.

  1990cites this paper
• Binding of the c-myb proto-oncogene product to the simian virus 40 enhancer stimulates transcription.

  1990cites this paper
• DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

  1990cites this paper
• Relationships Between Oncogenes and Growth Control

  1990cites this paper
• Alternative splicing of RNAs transcribed from the human c-myb gene

  1990cites this paper
• Effect of Oncogenes on Cell Differentiation

  1990cites this paper
• Transcriptional activation by human c-myb and v-myb genes.

  1990cites this paper
• Analysis of c-raf oncogene expression in gastrointestinal tumor cells.

  1989cites this paper
• Interaction of oncogenes with differentiation programs.

  1989cites this paper
• Restriction fragment length polymorphisms of L-myc and myb in human leukaemia and lymphoma in relation to age-selected controls.

  1989cites this paper
• A single amino-acid substitution in the DNA-binding domain of the myb oncogene confers a thermolabile phenotype to E26-transformed myeloid cells.

  1989cites this paper
• Multiple genes are transcribed in Hordeum vulgare and Zea mays that carry the DNA binding domain of the myb oncoproteins

  1989cites this paper
• The c-ets-1 protein is chromatin associated and binds to DNA in vitro.

  1989cites this paper
• Early reversible induction of leukotriene synthesis in chicken myelomonocytic cells transformed by a temperature-sensitive mutant of avian leukemia virus E26.

  1989cites this paper
• Murine myeloid cell lines derived by in vitro infection with recombinant c‐myb retroviruses express myb from rearranged vector proviruses.

  1989cites this paper
• Distribution of c-myc, c-myb, and Ki-67 antigens in interphase and mitotic human cells evidenced by immunofluorescence staining technique.

  1989cites this paper
• The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene.

  1989cites this paper
• Association of v-myc protein with chromatin.

  1989cites this paper
• A second c-myb protein is translated from an alternatively spliced mRNA expressed from normal and 5'-disrupted myb loci

  1989cites this paper
• Trans-activation by the c-myb proto-oncogene.

  1989cites this paper
• Cell cycle and oncogenes

  1989cites this paper
• Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb.

  1989cites this paper
• Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene.

  1989cites this paper
• Murine myeloid leukemias with aberrant myb loci show heterogeneous expression of novel myb proteins.

  1989cites this paper
• Identification of two translational products for c-myb.

  1989cites this paper
• Mapping of a small phosphopeptide at the carboxyterminus of the viral myb protein by monoclonal antibodies.

  1989cites this paper
• Isolation and characterization of the tax protein of HTLV-I.

  1989cites this paper
• Expression of p64c-myc and neuroendocrine properties define three subclasses of small cell lung cancer.

  1989cites this paper
• elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints.

  1989cites this paper
• Oncogene requirements for tumorigenicity: cooperative effects between retroviral oncogenes.

  1989cites this paper
• Transcriptional trans-repression by the c-myb proto-oncogene product.

  1989cites this paper
• Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation

  1988influential citation
• Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation

  1988cites this paper
• The induction of Friend erythroleukaemia differentiation is markedly affected by expression of a transfected c-myb cDNA.

  1988cites this paper
• Nuclear and cytoplasmic distribution of cellular myb protein in human haematopoietic cells evidenced by monoclonal antibody.

  1988cites this paper
• Viral myb oncogene encodes a sequence-specific DNA-binding activity

  1988cites this paper
• Interaction of myb proteins with nuclear matrix in vitro.

  1988cites this paper