Neuronal pathology in relation to molecular biology and treatment of Alzheimer's disease.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Molecular and cell biology of human diseases series

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-94-011-0709-9_2PMID 9439743
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intravenous physostigmine treatment of Alzheimer's disease evaluated by psychometric testing, regional cerebral blood flow (rCBF) measurement, and EEG

  2005cited by this paper
• High affinity serotonin binding sites in human brain: a comparison of cerebral cortex and basal ganglia

  2005cited by this paper
• Serotonin, memory, and the aging brain

  2005cited by this paper
• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Intravenous nicotine in Alzheimer's disease: a pilot study

  2004cited by this paper
• A new method for quenching correction leads to revisions of data in receptor autoradiography

  2004cited by this paper
• Separation of the associative and non-associative effects of brain serotonin released by p-chloroamphetamine: Dissociable serotoninergic involvement in avoidance learning, pain and motor function

  2004cited by this paper
• SDZ 216-525, a selective and potent 5-HT1A receptor antagonist.

  1993cited by this paper
• Antemortem measurements of neurotransmission: possible implications for pharmacotherapy of Alzheimer's disease and depression.

  1993cited by this paper
• Cortical Pyramidal Neurone Loss May Cause Glutamatergic Hypoactivity and Cognitive Impairment in Alzheimer's Disease: Investigative and Therapeutic Perspectives

  1993cited by this paper
• Alzheimer's disease: the amyloid cascade hypothesis.

  1992cited by this paper
• 5-Hydroxytryptamine1A but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin.

  1992cited by this paper
• beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

  1992cited by this paper
• Adenylyl Cyclase Activity in Postmortem Human Brain: Evidence of Altered G Protein Mediation in Alzheimer's Disease

  1992cited by this paper
• Serotonergic pathology is not widespread in Alzheimer patients without prominent aggressive symptoms

  1992cited by this paper
• Treatment strategies for Alzheimer's disease.

  1992cited by this paper
• A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease.

  1991cited by this paper
• Taking stock of cognition enhancers.

  1991cited by this paper
• Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.

  1991cited by this paper
• Somatostatin replacement therapy for alzheimer dementia

  1991cited by this paper
• 5-Hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex.

  1991cited by this paper
• Tacrine: a pharmacological review.

  1991cited by this paper
• The Prevalence of Dementia in Europe: A Collaborative Study of 1980–1990 Findings

  1991cited by this paper
• Glycine prodrug facilitates memory retrieval in humans

  1991cited by this paper
• Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus.

  1991cited by this paper
• Release of endogenous aspartate from rat cerebellum slices and synaptosomes: inhibition mediated by a 5-HT2 receptor and by a 5-HT1 receptor of a possibly novel subtype

  1991cited by this paper
• Characterisation of the Glycine Modulatory Site of the N‐Methyl‐d‐Aspartate Receptor‐Ionophore Complex in Human Brain

  1991cited by this paper
• Frequency and distribution of Alzheimer's disease in Europe: A collaborative study of 1980–1990 prevalence findings

  1991cited by this paper
• Therapy for Alzheimer's Disease: Choosing a Target

  1991cited by this paper
• Toward a Third Generation of Cholinesterase Inhibitors

  1991cited by this paper
• Destruction of a sub-population of cortical neurones by suicide transport of volkensin, a lectin from Adenia volkensii.

  1991cited by this paper
• Preservation of 5-hydroxytryptamine1A receptor-G protein interactions in the cerebral cortex of patients with Alzheimer's disease.

  1991cited by this paper
• The prevalence of dementia in Europe: a collaborative study of 1980-1990 findings. Eurodem Prevalence Research Group.

  1991cited by this paper
• Postsynaptic 5-HT1 receptors and offensive aggression in rats: a combined behavioural and autoradiographic study with eltoprazine.

  1991cited by this paper
• Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease

  1991cited by this paper
• Heptylphysostigmine — Novel Acetylcholinesterase Inhibitor: Biochemical and Behavioral Pharmacology

  1991cited by this paper
• Increased density of excitatory amino acid transport sites in the hippocampal formation following an entorhinal lesion.

  1991cited by this paper
• Intramuscular desferrioxamine in patients with Alzheimer's disease.

  1991cited by this paper
• Characterization of a novel and potent 5-hydroxytryptamine1A receptor antagonist.

  1991cited by this paper
• Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

  1991cited by this paper
• Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence.

  1991cited by this paper
• Robustness of G Proteins in Alzheimer's Disease: An Immunoblot Study

  1991cited by this paper
• Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation.

  1991cited by this paper
• 10. THA, A putative drug in the treatment of Alzheimer's disease?

  1990cited by this paper
• Lack of efficacy of hydergine in patients with Alzheimer's disease.

  1990cited by this paper
• Altered glucose metabolism in Alzheimer's disease

  1990cited by this paper
• The Clinical Efficacy of Citalopram in Treatment of Emotional Disturbances in Dementia Disorders a Nordic Multicentre Study

  1990cited by this paper
• Sodium-dependent D-aspartate 'binding' is not a measure of presynaptic neuronal uptake sites in an autoradiographic assay.

  1990cited by this paper
• G proteins in signal transduction.

  1990cited by this paper
• THA, a putative drug in the treatment of Alzheimer's disease?

  1990cited by this paper
• Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type.

  1990cited by this paper
• A topological model of the NMDA-glycine receptor model.

  1990cited by this paper
• A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease.

  1990cited by this paper
• Inhibition of spontaneous and evoked unit activity in the rat medial prefrontal cortex by mesencephalic raphe nuclei.

  1990cited by this paper
• Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease.

  1990cited by this paper
• Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors—an autoradiographic study

  1990cited by this paper
• Ante mortem cerebral amino acid concentrations indicate selective degeneration of glutamate-enriched neurons in Alzheimer's disease.

  1990cited by this paper
• Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2-activated interneuron.

  1990cited by this paper
• Alzheimer's disease: is there a problem beyond recognition?

  1990cited by this paper
• Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

  1990cited by this paper
• Treatment of Alzheimer's Disease

  1990cited by this paper
• Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias.

  1990cited by this paper
• Neuropsychiatric disorders and the multiple human brain serotonin receptor subtypes and subsystems.

  1990cited by this paper
• In situ hybridization histochemistry and the study of gene expression in the human brain.

  1990cited by this paper
• Enzyme Activities in Relation to pH and Lactate in Postmortem Brain in Alzheimer‐Type and Other Dementias

  1990cited by this paper
• Topography of the glycine site of the NMDA receptor

  1990cited by this paper
• Convergence and divergence of neurotransmitter action in human cerebral cortex.

  1989cited by this paper
• Reduced Glycine Stimulation of [3H]MK‐801 Binding in Alzheimer's Disease

  1989cited by this paper
• Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

  1989cited by this paper
• Tacrine, a Drug with Therapeutic Potential for Dementia: Post-Mortem Biochemical Evidence

  1989cited by this paper
• Hyperresponsivity to the serotonin agonist m-chlorophenylpiperazine in Alzheimer's disease. A controlled study.

  1989cited by this paper
• Excitatory amino acids and Alzheimer's disease.

  1989cited by this paper
• Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of later life.

  1989cited by this paper
• 5.HT1 receptors in the vertebrate brain

  1989cited by this paper
• The design of full agonists for the cortical muscarinic receptor.

  1989cited by this paper
• Loss of glycine-dependent radioligand binding to the N-methyl-D-aspartate-phencyclidine receptor complex in patients with Alzheimer's disease.

  1989cited by this paper
• Evidence of Glutamatergic Denervation and Possible Abnormal Metabolism in Alzheimer's Disease

  1988cited by this paper
• Cholinesterase and its molecular forms in pathological states.

  1988cited by this paper
• Possible neurotransmitter basis of behavioral changes in alzheimer's disease

  1988cited by this paper
• Galanin‐Like Immunoreactivity Is Unchanged in Alzheimer's Disease and Parkinson's Disease Dementia Cerebral Cortex

  1988cited by this paper
• Topographical distribution of neurochemical changes in Alzheimer's disease.

  1988cited by this paper
• Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer's disease.

  1988cited by this paper
• New Intrathecal Drugs in Alzheimer's Disease and Psychometric Testing

  1988cited by this paper
• A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease.

  1988cited by this paper
• Electrophysiological effects of tianeptine on rat locus coeruleus, raphe dorsalis, and hippocampus activity.

  1988cited by this paper
• Serotonin-glutamate interaction in rat cerebellum: involvement of 5-HT1 and 5-HT2 receptors.

  1988cited by this paper
• Cajal on the Cerebral Cortex: An Annotated Translation of the Complete Writings

  1988cited by this paper
• No response to high‐dose muscarinic agonist therapy in Alzheimer's disease

  1988cited by this paper
• Reductions in acetylcholine and nicotine binding in several degenerative diseases.

  1988cited by this paper
• Multiple-dose arecoline infusions in Alzheimer's disease.

  1988cited by this paper
• Somatostatin content and release measured in cerebral biopsies from demented patients.

  1987cited by this paper
• Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin

  1987cited by this paper
• Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus

  1987cited by this paper
• Induction of depression with oxotremorine in patients with Alzheimer's disease.

  1987cited by this paper
• Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.

  1987cited by this paper
• Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone

  1987cited by this paper
• Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors.

  1987cited by this paper
• Presynaptic Serotonergic Dysfunction in Patients with Alzheimer's Disease

  1987cited by this paper
• Serotonin receptors in the human brain--IV. Autoradiographic mapping of serotonin-2 receptors.

  1987cited by this paper
• Two distinct effects of 5-hydroxytryptamine on single cortical neurons.

  1987cited by this paper

• Approche temporelle de la mémoire de reconnaissance visuelle et atteinte au stade prodromal de la maladie d'Alzheimer

  2013cites this paper
• The role of oxidative stress and cholesterol in animal models of Alzheimer's disease

  2008cites this paper