Analysis of the RUNX3 gene methylation in serum DNA from esophagus squamous cell carcinoma, gastric and colorectal adenocarcinoma patients.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Hepato-Gastroenterology

• Publication date

  2011-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.5754/hge10016PMID 22234069
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epigenetic diagnostics of cancer — the application of DNA methylation markers

  2010cited by this paper
• The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome

  2009cited by this paper
• RUNX3 Inactivation in Colorectal Polyps Arising Through Different Pathways of Colonic Carcinogenesis

  2009cited by this paper
• RUNX3 Inhibits Cell Proliferation and Induces Apoptosis by TGF-β-Dependent and -Independent Mechanisms in Human Colon Carcinoma Cells

  2009cited by this paper
• Quantitative analysis of tumor-derived methylated RUNX3 sequences in the serum of gastric cancer patients.

  2009cited by this paper
• Loss of RUNX3 Expression Correlates with Differentiation, Nodal Metastasis, and Poor Prognosis of Gastric Cancer

  2009cited by this paper
• Differential Expression of RUNX Genes in Human Esophageal Squamous Cell Carcinoma: Downregulation of RUNX3 Worsens Patient Prognosis

  2008cited by this paper
• Detection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients.

  2008cited by this paper
• Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma

  2008cited by this paper
• RUNX3 inhibits growth of HCC cells and HCC xenografts in mice in combination with adriamycin

  2008cited by this paper
• Adverse prognosis of epigenetic inactivation in RUNX3 gene at 1p36 in human pancreatic cancer

  2008cited by this paper
• Inhibition of the growth and metastasis of human colon cancer by restoration of RUNX3 expression in cancer cells.

  2008cited by this paper
• Promoter Hypermethylation of the RUNX3 Gene in Esophageal Squamous Cell Carcinoma

  2007cited by this paper
• Hypermethylation of SFRP2 as a Potential Marker for Stool-Based Detection of Colorectal Cancer and Precancerous Lesions

  2007cited by this paper
• Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN‐1

  2007cited by this paper
• Circulating tumor cells and aberrant methylation as tumor markers in patients with esophageal cancer.

  2007cited by this paper
• Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis

  2007cited by this paper
• Expression of RUNX3 Protein in Human Esophageal Mucosa and Squamous Cell Carcinoma

  2006cited by this paper
• Comparison of serum aberrant methylation and conventional tumor markers in gastric cancer patients.

  2005cited by this paper
• Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis.

  2005cited by this paper
• CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer

  2005cited by this paper
• RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21WAF1/Cip1 Expression in Cooperation with Transforming Growth Factor β-Activated SMAD

  2005cited by this paper
• Hypermethylation of the RUNX3 gene in hepatocellular carcinoma

  2005cited by this paper
• Quantitative Detection of Promoter Hypermethylation in Multiple Genes in the Serum of Patients with Colorectal Cancer

  2005cited by this paper
• Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers

  2004cited by this paper
• Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma

  2004cited by this paper
• Frequent Loss of RUNX3 Expression by Promoter Hypermethylation in Gastric Carcinoma

  2004cited by this paper
• Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines

  2004cited by this paper
• RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells.

  2004cited by this paper
• Tumor Cell-Specific BRCA1 and RASSF1A Hypermethylation in Serum, Plasma, and Peritoneal Fluid from Ovarian Cancer Patients

  2004cited by this paper
• RUNX transcription factors as key targets of TGF-beta superfamily signaling.

  2003cited by this paper
• Promoter methylation status of DAP‐kinase and RUNX3 genes in neoplastic and non‐neoplastic gastric epithelia

  2003cited by this paper
• Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines

  2003cited by this paper
• Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor

  2002cited by this paper
• Causal relationship between the loss of RUNX3 expression and gastric cancer.

  2002cited by this paper
• Cancer epidemiology in the last century and the next decade

  2001cited by this paper
• DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

  2001cited by this paper

• Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma and its Clinical Implications in Systemic Chemotherapy

  2025cites this paper
• The Expression of TP63 as a Biomarker of Early Recurrence in Resected Esophageal Squamous Cell Carcinoma after Neoadjuvant Chemoradiotherapy

  2024cites this paper
• Using Circulating Tumor DNA as a Novel Biomarker to Screen and Diagnose Colorectal Cancer: A Meta-Analysis

  2023cites this paper
• Differential methylation of DNA promoter sequences in peripheral blood mononuclear cells as promising diagnostic biomarkers for colorectal cancer.

  2023cites this paper
• DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer

  2022cites this paper
• Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma: Biological and Clinical Implications

  2020cites this paper
• Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

  2020cites this paper
• SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes

  2019cites this paper
• Roles of Methylated DNA Biomarkers in Patients with Colorectal Cancer

  2019cites this paper
• Circulating Tumor DNA Analysis: Clinical Implications for Colorectal Cancer Patients. A Systematic Review

  2019cites this paper
• Aberrant promoter hypermethylation of p16, survivin, and retinoblastoma in gastric cancer

  2017cites this paper
• Aberrant promoter hypermethylation of p16, survivin, and retinoblastoma in gastric cancer.

  2017cites this paper
• The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma

  2016cites this paper
• Identification of a lncRNA involved functional module for esophageal cancer subtypes.

  2016cites this paper
• Hypermethylated DNA as a biomarker for colorectal cancer: a systematic review

  2016cites this paper
• MicroRNA-20a-5p targets RUNX3 to regulate proliferation and migration of human hepatocellular cancer cells.

  2016cites this paper
• Prognostic biomarker in advanced gastric cancer

  2016cites this paper
• Challenges of deciphering gastric cancer heterogeneity.

  2015cites this paper
• Relationship between RUNX3 methylation and hepatocellular carcinoma in Asian populations: a systematic review.

  2014cites this paper
• Relationship between RUNX 3 methylation and hepatocellular carcinoma in Asian populations : a systematic review

  2014cites this paper
• Methylation-mediated gene silencing as biomarkers of gastric cancer: a review.

  2014cites this paper
• DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer.

  2014cites this paper
• Association of Promoter Methylation of RUNX3 Gene with the Development of Esophageal Cancer: A Meta Analysis

  2014influential citation
• DNA Methylation in Aggressive Gastric Carcinoma

  2013cites this paper
• DNA and histone methylation in gastric carcinogenesis.

  2013cites this paper
• New Advances on Disease Biomarkers and Molecular Targets in Biomedicine

  2013cites this paper
• Epigenetic downregulation of RUNX3 by DNA methylation induces docetaxel chemoresistance in human lung adenocarcinoma cells by activation of the AKT pathway.

  2013cites this paper
• Molecular alterations and clinical relevance in esophageal squamous cell carcinoma

  2013cites this paper
• Serum protein and genetic tumor markers of gastric carcinoma.

  2013cites this paper
• Clinical significance of angiopoietin-like protein 4 expression in tissue and serum of esophageal squamous cell carcinoma patients

  2013cites this paper
• Using Genomic Biomarkers to Predict Patient Prognosis and Treatment Response in Gastric Cancer

  2013cites this paper
• The Epigenetics of Gastrointestinal Malignancies

  2012cites this paper
• Epigenetic mechanisms in gastric cancer.

  2012cites this paper