A Selective Role for the TNF p55 Receptor in Autocrine Signaling following IFN-γ Stimulation in Experimental Autoimmune Uveoretinitis1

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Immunology

• Publication date

  2005-11-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.175.10.6286PMID 16272279
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis.

  2004cited by this paper
• Molecular regulation of CD40 gene expression in macrophages and microglia.

  2004cited by this paper
• Anti-TNFalpha therapy modulates the phenotype of peripheral blood CD4+ T cells in patients with posterior segment intraocular inflammation.

  2004cited by this paper
• The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).

  2004cited by this paper
• Alternative activation of macrophages

  2003cited by this paper
• Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis.

  2003cited by this paper
• Critical role of tumor necrosis factor-alpha and NF-kappa B in interferon-gamma -induced CD40 expression in microglia/macrophages.

  2002cited by this paper
• CpG motifs in bacterial DNA and their immune effects.

  2002cited by this paper
• TH1 AND TH2 RESPONSES IN PATHOGENESIS AND REGULATION OF EXPERIMENTAL AUTOIMMUNE UVEORETINITIS

  2002cited by this paper
• Critical Role of Tumor Necrosis Factor-α and NF-κB in Interferon-γ-induced CD40 Expression in Microglia/Macrophages*

  2002cited by this paper
• Suppressor of Cytokine Signaling 1 Inhibits Cytokine Induction of CD40 Expression in Macrophages1

  2002cited by this paper
• Pattern recognition receptors: doubling up for the innate immune response.

  2002cited by this paper
• Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis.

  2002cited by this paper
• Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis.

  2002cited by this paper
• Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

  2001cited by this paper
• Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level

  2001influential reference
• Aqueous Humor and Serum Tumor Necrosis Factor-α in Clinical Uveitis

  2001cited by this paper
• Interphotoreceptor retinoid binding protein peptide-induced uveitis in B10.RIII mice: characterization of disease parameters and immunomodulation.

  2001cited by this paper
• Nitrosative Capacity of Macrophages Is Dependent on Nitric-oxide Synthase Induction Signals*

  2000cited by this paper
• Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis.

  2000influential reference
• Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype.

  2000cited by this paper
• TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes.

  1999cited by this paper
• Severity of symptoms and demyelination in MOG‐induced EAE depends on TNFR1

  1999influential reference
• Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats.

  1998cited by this paper
• Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype.

  1998cited by this paper
• TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation.

  1998cited by this paper
• Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis.

  1998cited by this paper
• Post‐transcriptional inhibition of CD40 gene expression in microglia by transforming growth factor‐β

  1998cited by this paper
• Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation

  1998cited by this paper
• Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines.

  1998influential reference
• Nitric oxide and macrophage function.

  1997cited by this paper
• Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism.

  1997cited by this paper
• Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina

  1996cited by this paper
• Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication.

  1996cited by this paper
• Two tumour necrosis factor receptors: structure and function.

  1995cited by this paper
• The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor.

  1995cited by this paper
• Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75

  1995cited by this paper
• Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice.

  1995cited by this paper
• Dissociation of TNF- cytotoxic and proinflammatory activities by p55 and p75 receptor-selective TNF- mutants

  1994cited by this paper
• Dissociation of TNF‐alpha cytotoxic and proinflammatory activities by p55 receptor‐ and p75 receptor‐selective TNF‐alpha mutants.

  1994cited by this paper
• Immunomodulation of experimental autoimmune uveoretinitis: A model of tolerance induction with retinal antigens

  1994cited by this paper
• Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis.

  1993cited by this paper
• Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

  1993influential reference
• Molecular cloning and expression of a receptor for human tumor necrosis factor.

  1990cited by this paper
• Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor.

  1990cited by this paper

• Rescue Treatment with Infliximab for a Bilateral, Severe, Sight Threatening Frosted Branch Angiitis Associated with Concomitant Acute Onset of Presumed Dermatomyositis

  2022cites this paper
• Introduction to Pharmacology of Macrophages with Drug Delivery Perspective

  2022cites this paper
• The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

  2018cites this paper
• Inhibition of lymphocyte proliferation: An ability shared by murine mesenchymal stem cells, dermal fibroblasts and chondrocytes.

  2018cites this paper
• Doyne lecture 2016: intraocular health and the many faces of inflammation

  2017cites this paper
• Dry eye disease and uveitis: A closer look at immune mechanisms in animal models of two ocular autoimmune diseases.

  2016cites this paper
• The Role of Lipoprotein-Associated Phospholipase A₂ in a Murine Model of Experimental Autoimmune Uveoretinitis

  2015cites this paper
• Local targeting of the CD200-CD200R axis does not promote corneal graft survival.

  2015cites this paper
• Macrophages and Uveitis in Experimental Animal Models

  2015cites this paper
• Autoimmune and autoinflammatory mechanisms in uveitis

  2014cites this paper
• Assessment and In Vivo Scoring of Murine Experimental Autoimmune Uveoretinitis Using Optical Coherence Tomography

  2013cites this paper
• Toll like receptor (TLR)-induced differential expression of microRNAs (MiRs) promotes proper immune response against infections: a systematic review.

  2013cites this paper
• Therapeutic dosing of FTY720 (Fingolimod) prevents cell infiltrate, rapidly suppresses ocular inflammation and maintains blood-ocular barrier

  2013cites this paper
• Loss of TNF Signaling Facilitates the Development of a Novel Ly-6Clow Macrophage Population Permissive for Leishmania major Infection

  2012cites this paper
• Activation des cellules rétiniennes lors d'uvéites autoimmunes expérimentales: rôle des cytokines pro-inflammatoires et effet du transfert du gène SOCS1

  2012cites this paper
• CD40 and tumour necrosis factor‐α co‐operate to up‐regulate inducuble nitric oxide synthase expression in macrophages

  2012cites this paper
• An Essential Role for Death Receptor 3 in Experimental Autoimmune Uveoretinitis

  2012cites this paper
• Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier.

  2012cites this paper
• Interplay between innate and adaptive immunity in the development of non-infectious uveitis.

  2012cites this paper
• TNFα suppresses IFNγ‐induced MHC class II expression on retinal pigmented epithelial cells cultures

  2012cites this paper
• Leishmania major Macrophage Population Permissive for lowDevelopment of a Novel Ly-6 C Loss of TNF Signaling Facilitates

  2012cites this paper
• Gene Therapy for Noninfectious Uveitis

  2012cites this paper
• Environmental conditioning in the control of macrophage thrombospondin-1 production

  2012cites this paper
• Tumour necrosis factor‐mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis

  2012cites this paper
• The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases

  2011cites this paper
• Roles of the Ribosomal Protein S19 Dimer and Chemically Induced Apoptotic Cells as a Tumor Vaccine in Syngeneic Mouse Transplantation Models

  2011influential citation
• Requirement of the Acquired Immune System in Successful Cancer Chemotherapy With cis-Diamminedichloroplatinum (II) in a Syngeneic Mouse Tumor Transplantation Model

  2011cites this paper
• IL-33 Reduces Macrophage Foam Cell Formation

  2010cites this paper
• The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro

  2010cites this paper
• TNFR1 signalling is a critical checkpoint for developing macrophages that control of T‐cell proliferation

  2010cites this paper
• Prevention of experimental autoimmune uveoretinitis by blockade of osteopontin with small interfering RNA.

  2010cites this paper
• Mechanisms of TNFα regulation in uveitis: focus on RNA-binding proteins.

  2010cites this paper
• Immune mechanisms of intraocular inflammation

  2010cites this paper
• Dissociation of interferon-gamma production and resistance to leishmaniasis in the absence of tumor necrosis factor

  2010cites this paper
• Indirect action of tumor necrosis factor‐alpha in liver injury during the CD8+ T cell response to an adeno‐associated virus vector in mice

  2009cites this paper
• Clinical Review: Anti-TNFα Therapies in Uveitis: Perspective on 5 Years of Clinical Experience

  2009cites this paper
• TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis1

  2009influential citation
• The role of glia, mitochondria, and the immune system in glaucoma.

  2009cites this paper
• The Role of Glia, Mitochondria, and the Immune System in Glaucoma

  2009cites this paper
• Anti‐inflammatory effects of tumour necrosis factor (TNF)‐α are mediated via TNF‐R2 (p75) in tolerogenic transforming growth factor‐β‐treated antigen‐presenting cells

  2009cites this paper
• Monocyte dependent regulation of autoimmune inflammation.

  2009cites this paper
• TNFR 1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis 1

  2009influential citation
• The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

  2008cites this paper
• The roles of IL‐17A in inflammatory immune responses and host defense against pathogens

  2008cites this paper
• The B subunit of Escherichia coli heat-labile enterotoxin inhibits Th1 but not Th17 cell responses in established experimental autoimmune uveoretinitis.

  2008cites this paper
• TNF Activation and Nitric Oxide Production in EAU

  2008cites this paper
• Anti-inflammatory and immunomodulatory properties of 2-amino-3H-phenoxazin-3-one.

  2008cites this paper
• The dynamics of leukocyte infiltration in experimental autoimmune uveoretinitis.

  2008cites this paper
• TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.

  2007cites this paper
• TNF-α is critical for antitumor but not antiviral T cell immunity in mice

  2007cites this paper
• Identification of novel dendritic cell populations in normal mouse retina.

  2007cites this paper
• This information is current as Autoimmune Uveoretinitis in Mice Osteopontin Aggravates Experimental

  2007cites this paper
• MicroRNA-155 is induced during the macrophage inflammatory response

  2007cites this paper
• Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis.

  2007cites this paper