Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Neuroimmunology

• Publication date

  1993-09-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0165-5728(93)90028-WPMID 8370769
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Immune responses to Legionella pneumophila in athymic nude rats.

  2009cited by this paper
• T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions

  1992cited by this paper
• Control of experimental autoimmune uveoretinitis by low dose T cell vaccination.

  1992cited by this paper
• Selective localisation of neuro-specific T lymphocytes in the central nervous system.

  1992cited by this paper
• The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions.

  1992cited by this paper
• Limited heterogeneity of rearranged T-cell receptor V α transcripts in brains of multiple sclerosis patients

  1991cited by this paper
• Conserved T cell receptor V gene usage by uveitogenic T cells.

  1991cited by this paper
• Therapy against murine collagen‐induced arthritis with T cell receptor Vβ‐specific antibodies

  1991cited by this paper
• Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals.

  1991cited by this paper
• T cell receptor β-chain usage in experimental autoimmune uveoretinitis

  1991cited by this paper
• T cell receptor beta-chain usage in experimental autoimmune uveoretinitis.

  1991cited by this paper
• Identification of a potent new pathogenic site in human retinal S-antigen which induces experimental autoimmune uveoretinitis in LEW rats.

  1990cited by this paper
• Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients

  1990cited by this paper
• Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis.

  1990cited by this paper
• Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein.

  1990cited by this paper
• Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different

  1989cited by this paper
• Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

  1989cited by this paper
• Clonal heterogeneity of synovial fluid T lymphocytes from patients with rheumatoid arthritis.

  1989cited by this paper
• Schistosoma mansoni‐specific rat T cell clones. II. Different effects of adult worm‐specific T cell clones in immunocompetent and nude infected rats

  1989cited by this paper
• Activation requirements of donor T cells and host T cell recruitment in adoptive transfer of murine experimental autoimmune orchitis (EAO).

  1989cited by this paper
• Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP)

  1989cited by this paper
• Analysis of T-cell receptor usage in activated T-cell clones from Hashimoto's thyroiditis and Graves' disease.

  1989cited by this paper
• T cell differentiation in athymic nude rats (rnu/rnu): demonstration of a distorted t cell subset structure by flow cytometry analysis

  1989cited by this paper
• Dynamics of experimental autoimmune uveoretinitis induced by adoptive transfer of S-antigen-specific T cell line.

  1988cited by this paper
• Thymus-dependent and -independent regulation of Ia antigen expression in situ by cells in the synovium of rats with streptococcal cell wall-induced arthritis. Differences in site and intensity of expression in euthymic, athymic, and cyclosporin A-treated LEW and F344 rats.

  1987cited by this paper
• Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system

  1987cited by this paper
• Antigen-directed retention of an autoimmune T-cell line.

  1987cited by this paper
• T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat.

  1986cited by this paper
• Chapter 3 Retinal specific antigens and immunopathogenic processes they provoke

  1986cited by this paper
• Studies of experimental allergic encephalomyelitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice.

  1986cited by this paper
• The response of the nude (athymic) rat to actively induced and adoptively transferred experimental allergic encephalomyelitis.

  1983cited by this paper
• Infection of the congenitally athymic rat with Mycobacterium leprae.

  1983cited by this paper
• Experimental autoimmune uveitis in the athymic nude rat

  1982cited by this paper
• The Laboratory Rat, Volume II: Research Applications

  1980cited by this paper
• Allergic Encephalomyelitis: New Form Featuring Polymorphonuclear Leukocytes

  1971cited by this paper
• Allergic encephalomyelitis: inhibition of cellular passive transfer by x-irradiation.

  1969cited by this paper
• Cyclophosphamide inhibition of experimental allergic encephalomyelitis and cellular transfer of the disease in Lewis rats.

  1969cited by this paper
• STATISTICAL METHODS

  1967cited by this paper
• Allergic Encephalomyelitis

  1958cited by this paper

• Comparative models of uveitis

  2025cites this paper
• Glycan Signatures on Neutrophils in an Equine Model for Autoimmune Uveitis

  2025cites this paper
• miR142 silencing alleviates retinal inflammation by impairing mitochondrial function and reprogramming metabolism of CD4+ T cells via targeting MTFR1.

  2025cites this paper
• Unveiling Differential Responses of Granulocytes to Distinct Immunostimulants with Implications in Autoimmune Uveitis

  2023cites this paper
• Hydroxychloroquine Alleviates EAU by Inhibiting Uveitogenic T Cells and Ameliorating Retinal Vascular Endothelial Cells Dysfunction

  2022influential citation
• Pre-Activated Granulocytes from an Autoimmune Uveitis Model Show Divergent Pathway Activation Profiles upon IL8 Stimulation In Vitro

  2022cites this paper
• Immunological Insights in Equine Recurrent Uveitis

  2021cites this paper
• Anti-inflammatory Effects of GTE in Eye Diseases

  2021cites this paper
• Deviant proteome profile of equine granulocytes associates to latent activation status in organ specific autoimmune disease.

  2020cites this paper
• Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression

  2019cites this paper
• Immunologie oculaire: bases physiopathologiques

  2017cites this paper
• Quantitative Characterization of Autoimmune Uveoretinitis in an Experimental Mouse Model.

  2017cites this paper
• Doyne lecture 2016: intraocular health and the many faces of inflammation

  2017cites this paper
• An experimental autoimmune uveoretinitis model and intraocular inflammation

  2016cites this paper
• G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis.

  2016cites this paper
• The Role of Interleukin-22 and Its Receptor in the Development and Pathogenesis of Experimental Autoimmune Uveitis

  2016cites this paper
• 36 – Uveitic Glaucoma

  2015cites this paper
• Environmental Microbes and Uveitis: Is Microbial Exposure Always Bad?

  2015cites this paper
• Inaugural-Dissertation zur Erlangung der Doktorwürde der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München Untersuchungen zu Septin7 und anderen differentiell regulierten Lymphozytenproteinen bei der equinen rezidivierenden Uveitis

  2015cites this paper
• Uveitis and glaucoma: new insights in the pathogenesis and treatment.

  2015cites this paper
• Autoimmune and autoinflammatory mechanisms in uveitis

  2014cites this paper
• CD73 expression in RPE cells is associated with the suppression of conventional CD4 cell proliferation.

  2014influential citation
• but Differ in Other Key Biological Activities Both Th1 and Th17 Are Immunopathogenic

  2013cites this paper
• Therapeutic dosing of FTY720 (Fingolimod) prevents cell infiltrate, rapidly suppresses ocular inflammation and maintains blood-ocular barrier

  2013cites this paper
• Genetics of chemokines & cytokines in non-infectious posterior segment uveitis

  2013cites this paper
• Vascular Adhesion Protein 1 in the Eye

  2013cites this paper
• Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier.

  2012cites this paper
• Characterization of retinal expression of vascular cell adhesion molecule (VCAM-1) during experimental autoimmune uveitis.

  2012cites this paper
• Everolimus improves experimental autoimmune uveoretinitis.

  2012cites this paper
• Protective effect of pristane on experimental autoimmune uveitis.

  2011cites this paper
• Le monoxyde d’azote, bio-marqueur de l’uvéite auto-immune expérimentale induite par l’antigène S

  2010cites this paper
• [Nitric oxide, biomarker of experimental autoimmune uveitis induced by S antigen].

  2010cites this paper
• Anti-inflammatory treatment of uveitis with biologicals: new treatment options that reflect pathogenetic knowledge of the disease

  2010cites this paper
• A look at autoimmunity and inflammation in the eye.

  2010cites this paper
• Unlike Th1, Th17 Cells Mediate Sustained Autoimmune Inflammation and Are Highly Resistant to Restimulation-Induced Cell Death1

  2009cites this paper
• Both Th1 and Th17 Are Immunopathogenic but Differ in Other Key Biological Activities1

  2008cites this paper
• New perspectives on effector mechanisms in uveitis

  2008cites this paper
• Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 Cells1

  2008cites this paper
• Alternative routes of immunization for the uveoretinitis ( EAU ) in rodents : a comparison

  2007cites this paper
• Active participation of antigen nonspecific lymphoid cells in immune-mediated inflammation

  2007cites this paper
• Retinal Mueller glial cells trigger the hallmark inflammatory process in autoimmune uveitis.

  2007cites this paper
• Active Participation of Antigen-Nonspecific Lymphoid Cells in Immune-Mediated Inflammation1

  2006cites this paper
• Sialoadhesin Promotes the Inflammatory Response in Experimental Autoimmune Uveoretinitis1

  2006cites this paper
• Blockade of the interaction of leukotriene b4 with its receptor prevents development of autoimmune uveitis.

  2006cites this paper
• This information is current as Uveoretinitis Response in Experimental Autoimmune Sialoadhesin Promotes the Inflammatory

  2006cites this paper
• The Nude Rat

  2006cites this paper
• Charakterisierung des potenziellen Autoantigens cRALBP

  2005cites this paper
• Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis.

  2005cites this paper
• A Selective Role for the TNF p55 Receptor in Autocrine Signaling following IFN-γ Stimulation in Experimental Autoimmune Uveoretinitis1

  2005cites this paper
• Effects of Intravitreal Injection of Tacrolimus (FK506) in Experimental Uveitis

  2005cites this paper
• The effect of the CC chemokine receptor antagonist Met-RANTES on experimental autoimmune uveitis and oral tolerance.

  2005cites this paper
• Immune mechanisms in uveitis

  2004cites this paper
• The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).

  2004cites this paper
• Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis.

  2003cites this paper
• Regulation, counter-regulation, and immunotherapy of autoimmune responses to immunologically privileged retinal antigens

  2003cites this paper
• Control of myeloid activity during retinal inflammation

  2003cites this paper
• Cytokines and immunopathogenesis of intraocular posterior segment inflammation

  2003cites this paper
• Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis.

  2002cites this paper
• The “all online” BJO—why?

  2002cites this paper
• IMAGING OCULAR IMMUNE RESPONSES BY INTRAVITAL MICROSCOPY

  2002cites this paper
• Identification of Th2‐type suppressor T cells among in vivo expanded ocular T cells in mice with experimental autoimmune uveoretinitis

  2001cites this paper
• Distribution of OX2 antigen and OX2 receptor within retina.

  2001cites this paper
• Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE.

  2001cites this paper
• Pertussis Toxin Inhibits Induction of Tissue-Specific Autoimmune Disease by Disrupting G Protein-Coupled Signals

  2001cites this paper
• Disrupting G Protein-Coupled Signals Tissue-Specific Autoimmune Disease by Pertussis Toxin Inhibits Induction of

  2001cites this paper
• On the role of peripheral macrophages during active experimental allergic encephalomyelitis (EAE)

  2001cites this paper
• Restricted and shared patterns of TCR beta-chain gene expression in silicone breast implant capsules and remote sites of tissue inflammation.

  2000cites this paper
• Immune Mechanisms of Uveitis: Insights Into Disease Pathogenesis and Treatment

  2000cites this paper
• Induction of experimental autoimmune keratitis by adoptive transfer of human corneal antigen-specific T-cell line.

  2000cites this paper
• Modulating phenotype and cytokine production of leucocytic retinal infiltrate in experimental autoimmune uveoretinitis following intranasal tolerance induction with retinal antigens

  1999cites this paper
• IL-4 potentiates IL-1beta- and TNF-alpha-stimulated IL-8 and MCP-1 protein production in human retinal pigment epithelial cells.

  1999cites this paper
• Immune regulation of uveoretinal inflammation.

  1999cites this paper
• Effects of mycophenolate mofetil on nasal mucosal tolerance induction.

  1998cites this paper
• Acute immunosuppression and syngeneic bone marrow transplantation in ocular autoimmunity abort disease, but do not result in induction of long-term protection.

  1998cites this paper
• Leukocyte trafficking in experimental autoimmune uveitis in vivo

  1998cites this paper
• Experimental mucosal induction of uveitis with the 60‐kDa heat shock protein‐derived peptide 336 – 351

  1998cites this paper
• Phenotypic analysis of retinal leukocyte infiltration during combined cyclosporin A and nasal antigen administration of retinal antigens: delay and inhibition of macrophage and granulocyte infiltration.

  1997cites this paper
• A new method for studying the selective adherence of blood lymphocytes to the microvasculature of human retina.

  1997cites this paper
• T cell directed immunotherapy of inflammatory demyelination in the peripheral nervous system. Potent suppression of the effector phase of experimental autoimmune neuritis by anti-CD2 antibodies.

  1996cites this paper
• Establishment and characterization of a murine CD4+ T cell line and clone that induce experimental autoimmune uveoretinitis in B10.A mice.

  1996cites this paper
• Resident and infiltrating immune cells in the uveal tract in the early and late stages of experimental autoimmune uveoretinitis.

  1996cites this paper
• Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina

  1996cites this paper
• Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming.

  1996cites this paper
• Retinal antigen-specific T cells mediate experimental autoimmune uveoretinitis (EAU) in PVG rat a model for tracking antigen-specific CD4(+) T cells in the inflamed eye.

  1995cites this paper
• Alternative routes of immunization for the induction of experimental autoimmune uveoretinitis (EAU) in rodents: a comparison.

  1995cites this paper
• The Blood-Retinal Barrier in Immune-Mediated Diseases of the Retina

  1995cites this paper
• The kinetics of cytokine mRNA expression in the retina during experimental autoimmune uveoretinitis.

  1995cites this paper
• Immune corticotropin-releasing hormone is present in the eyes of and promotes experimental autoimmune uveoretinitis in rodents.

  1995cites this paper
• Immunotolerance and prevention of ocular autoimmune disease.

  1995cites this paper
• Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents.

  1995cites this paper
• Reverse immunology: the lessons from myositis.

  1994cites this paper
• Experimental Autoimmune Uveoretinitis—Rat and Mouse

  1994cites this paper
• Uveitogenic T lymphocytes in the rat: pathogenicity vs. lymphokine production, adhesion molecules and surface antigen expression.

  1994cites this paper
• The alpha beta T-cell receptor repertoire in inclusion body myositis: diverse patterns of gene expression by muscle-infiltrating lymphocytes.

  1994cites this paper
• Death Resistant to Restimulation-induced Cell Autoimmune Inflammation and Are Highly unlike Th1, Th17 Cells Mediate Sustained

  year unknowncites this paper