Medial prefrontal cortex lesions in the female rat affect sexual and maternal behavior and their sequential organization.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Behavioral Neuroscience

• Publication date

  2007-06-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1037/0735-7044.121.3.515PMID 17592942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice.

  2006cited by this paper
• Potential contributions of efferents from medial prefrontal cortex to neural activation following sexual behavior in the male rat.

  2006cited by this paper
• Knobil and Neill's Physiology of reproduction

  2006cited by this paper
• CHAPTER 43 – Neuroendocrine Control of the Ovarian Cycle of the Rat

  2006cited by this paper
• Electrical activity of prefrontal cortex and ventral tegmental area during rat maternal behavior.

  2005cited by this paper
• Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates.

  2004cited by this paper
• Artificially-reared female rats show reduced prepulse inhibition and deficits in the attentional set shifting task--reversal of effects with maternal-like licking stimulation.

  2004cited by this paper
• NMDA lesions in the medial prefrontal cortex impair the ability to inhibit responses during reversal of a simple spatial discrimination.

  2004cited by this paper
• Recovery from early cortical damage in rats. IX. Differential behavioral and anatomical effects of temporal cortex lesions at different ages of neural maturation.

  2003cited by this paper
• Recovery from early cortical damage in rats. I. Differential behavioral and anatomical effects of frontal lesions at different ages of neural maturation.

  2003cited by this paper
• Do rats have a prefrontal cortex?

  2003cited by this paper
• Mating stimulation required for mating-induced estrous abbreviation in female rats: effects of repeated testing.

  2002cited by this paper
• Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain.

  2002cited by this paper
• Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

  2001cited by this paper
• Sensory cues mediating mating-induced potentiation of sexual receptivity in female rats.

  2001cited by this paper
• The prefrontal cortex and the integration of sensory, limbic and autonomic information.

  2000cited by this paper
• Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon.

  2000cited by this paper
• Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. II. Patterns of estrus termination following vaginocervical stimulation.

  2000cited by this paper
• Medial Frontal Cortex Mediates Perceptual Attentional Set Shifting in the Rat

  2000cited by this paper
• Visual attention task performance in Wistar and Lister hooded rats: response inhibition deficits after medial prefrontal cortex lesions.

  1999cited by this paper
• Cytotoxic lesion of the medial prefrontal cortex abolishes the partial reinforcement extinction effect, attenuates prepulse inhibition of the acoustic startle reflex and induces transient hyperlocomotion, while sparing spontaneous object recognition memory in the rat.

  1999cited by this paper
• Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones.

  1999cited by this paper
• Site and behavioral specificity of periaqueductal gray lesions on postpartum sexual, maternal, and aggressive behaviors in rats.

  1998cited by this paper
• Implications of immediate-early gene induction in the brain following sexual stimulation of female and male rodents.

  1997cited by this paper
• Function of intromissions on intromission-return latency of female rats during paced sexual behavior

  1997cited by this paper
• Function of intromissions on intromission-return latency of female rats during paced sexual behavior.

  1997cited by this paper
• Effects of paced mating and intromissive stimulation on feminine sexual behavior and estrus termination in the cycling rat.

  1996cited by this paper
• Trigeminal lesions and maternal behavior in Norway rats: II. Disruption of parturition.

  1996cited by this paper
• A relationship between inhibition of the acoustic startle response and the protection of prepulse processing

  1996cited by this paper
• Increased sensitivity to the sensorimotor gating-disruptive effects of apomorphine after lesions of medial prefrontal cortex or ventral hippocampus in adult rats

  1995cited by this paper
• Maternal aggression in rats: effects of olfactory bulbectomy, ZnSO4-induced anosmia, and vomeronasal organ removal.

  1995cited by this paper
• Lesions of the medial prefrontal cortex and sexual behavior in the male rat.

  1995cited by this paper
• Effects of ovarian hormones on sexual receptivity, proceptivity, and motivation in olfactory bulbectomized female rats.

  1991cited by this paper
• Trigeminal lesions and maternal behavior in Norway rats: I. Effects of cutaneous rostral snout denervation on maintenance of nurturance and maternal aggression.

  1991cited by this paper
• Ventral somatosensory determinants of nursing behavior in Norway rats. I. Effects of variations in the quality and quantity of pup stimuli.

  1990cited by this paper
• A correlational and factor analysis of anticipatory and consummatory measures of sexual behavior in the male rat.

  1990cited by this paper
• The Cerebral cortex of the rat

  1990cited by this paper
• The Prefrontal Cortex

  1989cited by this paper
• Solicitation behavior in the estrous female rat: a review.

  1989cited by this paper
• Perioral anesthesia disrupts maternal behavior during early lactation in Long-Evans rats.

  1989cited by this paper
• The Physiology of reproduction

  1988cited by this paper
• Recovery from early cortical damage in rats. IV. Effects of hemidecortication at 1, 5 or 10 days of age on cerebral anatomy and behavior.

  1988cited by this paper
• Maternal behavior.

  1986cited by this paper
• Increased estrogen receptor binding in amygdala correlates with facilitation of feminine sexual behavior induced by olfactory bulbectomy.

  1985cited by this paper
• Effect of lesion location within the medial preoptic-anterior hypothalamic continuum on maternal and male sexual behaviors in female rats.

  1984cited by this paper
• A quantitative analysis of the roles of dosage, sequence, and duration of estradiol and progesterone exposure in the regulation of maternal behavior in the rat.

  1984cited by this paper
• Lesions confined to the ventromedial hypothalamus decrease the frequency of coital contacts in female rats.

  1984cited by this paper
• A comparison of the contributions of the frontal and parietal association cortex to spatial localization in rats.

  1983cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• Role of the infraorbital nerve in retrieving behavior in lactating rats.

  1983cited by this paper
• Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat.

  1982cited by this paper
• Neurobiological Mechanisms of Sexual Motivation

  1982cited by this paper
• Induction of female and male mating patterns in female rats by gonadal steroids: effects of neonatal or adult olfactory bulbectomy.

  1981cited by this paper
• Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input.

  1980cited by this paper
• Estrogens and brain function : neural analysis of a hormone-controlled mammalian reporductive behavior

  1980cited by this paper
• From motivation to action: functional interface between the limbic system and the motor system.

  1980cited by this paper
• Disruption of maternal behavior in rats with lesions of the septal area.

  1978cited by this paper
• Induction of persistent estrus by airborne chemical communication among female rats.

  1978cited by this paper
• The Rat: A Study in Behavior.

  1977cited by this paper
• Role of pelvic nerves in the postcopulatory abbreviation of behavioral estrus in female rats.

  1976cited by this paper
• Sexual attractivity, proceptivity, and receptivity in female mammals.

  1976cited by this paper
• Olfactory regulation of maternal behavior in rats. II. Effects of peripherally induced anosmia and lesions of the lateral olfactory tract in pup-induced virgins.

  1974cited by this paper
• Olfactory regulation of maternal behavior in rats. I. Effects of olfactory bulb removal in experienced and inexperienced lactating and cycling females.

  1974cited by this paper
• Maternal Behavior in the Rat: Facilitation through Gonadectomy

  1973cited by this paper
• Olfactory bulb removal facilitates the hormonal induction of sexual receptivity in the female rat

  1972cited by this paper
• Olfactory bulb removal vs peripherally induced anosmia: differential effects on the aggressive behavior of male mice.

  1972cited by this paper
• Hormonal induction of maternal behavior in the ovariectomized nulliparous rat.

  1970cited by this paper
• Nature of sex hormone effects on rat sex behavior: specificity of effects and individual patterns of response.

  1970cited by this paper
• The function of the median cerebral cortex in maternal behavior of rats.

  1955cited by this paper

• Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice

  2026cites this paper
• GABAergic neuroactive steroids and network states: relevance to peripartum depression.

  2025cites this paper
• Why do mood disturbances often occur in early postpartum? An integrative neurobiological and evolutionary perspective.

  2025cites this paper
• Neural basis of aggressive behavior toward newborns in Mice: Advances and future Challenges.

  2025cites this paper
• Differential Effects of Central Dopamine D2 Receptor Activation on the Dynamic Changes of Maternal Behavior Throughout the Postpartum Period.

  2025cites this paper
• Neural plasticity supporting parental behaviors.

  2025cites this paper
• Neuroanatomical basis of 5-HT1A receptor agonism in disruption of maternal behavior in rats.

  2025cites this paper
• Roadmap for maternal behavior research in domestic dogs: lessons from decades of laboratory rodent work

  2024cites this paper
• Peripartum buprenorphine and oxycodone exposure impair maternal behavior and increase neuroinflammation in the brains of new mother rats.

  2024cites this paper
• PVN-mPFC OT projections modulate pup-directed pup care or attacking in virgin mandarin voles

  2024cites this paper
• Antidepressant effects of activation of infralimbic cortex via upregulation of BDNF and β-catenin in an estradiol withdrawal model

  2024cites this paper
• PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles

  2024cites this paper
• Instinct to insight: Neural correlates of ethological strategy learning

  2023cites this paper
• Using lickometry to infer differential contributions of salience network regions during compulsion-like alcohol drinking

  2023cites this paper
• Microglia depletion facilitates the display of maternal behavior and alters activation of the maternal brain network in nulliparous female rats

  2023cites this paper
• Experience-Regulated Neuronal Signaling in Maternal Behavior

  2022cites this paper
• Postpartum State, but Not Maternal Caregiving or Level of Anxiety, Increases Medial Prefrontal Cortex GAD65 and vGAT in Female Rats

  2022cites this paper
• Neonatal ventral hippocampus lesion disrupts maternal behavior in rats: An animal model of schizophrenia.

  2022cites this paper
• 8-OH-DPAT enhances dopamine D2-induced maternal disruption in rats

  2022influential citation
• Neural mechanisms of sexual decision-making in women with alcohol use disorder

  2021cites this paper
• Cortico-cortical connectivity behind acoustic information transfer to mouse orbitofrontal cortex is sensitive to neuromodulation and displays local sensory gating: relevance in disorders with auditory hallucinations?

  2021cites this paper
• Maternal Behavior, Novelty Confrontation, and Subcortical c-Fos Expression during Lactation Period are Shaped by Gestational Environment.

  2021cites this paper
• I. Antidepressants and sexual behavior: Weekly ketamine injections increased sexual behavior initially in female and male rats.

  2020cites this paper
• Involvement of ventral pallidal vasopressin in the sex-specific regulation of sociosexual motivation in rats.

  2020cites this paper
• Brain orchestration of pregnancy and maternal behavior in mice

  2020cites this paper
• Chronic effects of maternal tobacco-smoke exposure and/or α-lipoic acid treatment on reproductive parameters in female rat offspring

  2020cites this paper
• II. Antidepressants and sexual behavior: Acute fluoxetine, but not ketamine, disrupts paced mating behavior in sexually experienced female rats.

  2020cites this paper
• Neural Circuit Mechanisms That Underlie Parental Care.

  2020cites this paper
• Infralimbic Cortex Biases Preference Decision Making for Offspring over Competing Cocaine-Associated Stimuli in New Mother Rats

  2020cites this paper
• The influence of microsatellite polymorphisms in sex steroid receptor genes ESR1, ESR2 and AR on sex differences in brain structure

  2020cites this paper
• Psychological and Neurobiological Mechanisms Underlying the Decline of Maternal Behavior.

  2020cites this paper
• Vaporized Cannabis differentially modulates sexual behavior of female rats according to the dose.

  2019cites this paper
• Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice

  2019cites this paper
• Serotonin 5-HT2A and 5-HT2C Receptors Regulate Rat Maternal Behavior through Distinct Behavioral and Neural mechanisms.

  2019influential citation
• 5-HT2A receptors modulate dopamine D2-mediated maternal effects.

  2019influential citation
• Inter‐individual maternal care received and genotype interactions affect dopaminergic phenotypes in female rat offspring

  2019cites this paper
• Glutamatergic Signals in the Dorsal Raphe Nucleus Regulate Maternal Aggression and Care in an Opposing Manner in Mice.

  2019cites this paper
• Molecular and Genetic Bases of Mammalian Maternal Behavior

  2019cites this paper
• Depression‐related disturbances in rat maternal behaviour are associated with altered monoamine levels within mesocorticolimbic structures

  2019cites this paper
• Pharmacological manipulation of DNA methylation normalizes maternal behavior, DNA methylation, and gene expression in dams with a history of maltreatment

  2019cites this paper
• Prefrontal Cortex and Multiparity in Lactation.

  2019cites this paper
• Rats selectively bred for showing divergent behavioral traits in response to stress or novelty or spontaneous yawning with a divergent frequency show similar changes in sexual behavior: the role of dopamine

  2018cites this paper
• Contributions of mothers' and fathers' parenting to children's self-regulation: Evidence from an adoption study.

  2018cites this paper
• Blockade of serotonin 5‐HT2A receptors potentiates dopamine D2 activation‐induced disruption of pup retrieval on an elevated plus maze, but has no effect on D2 blockade‐induced one

  2018cites this paper
• Cortical thickness variation of the maternal brain in the first 6 months postpartum: associations with parental self-efficacy

  2018cites this paper
• Verbal and visuospatial working memory during pregnancy: EEG correlation between the prefrontal and parietal cortices

  2018cites this paper
• CPS-Referred Mothers’ Psychophysiological Responses to Own Versus Other Child Predict Sensitivity to Child Distress

  2018cites this paper
• Gating of the neuroendocrine stress responses by stressor salience in early lactating female rats is independent of infralimbic cortex activation and plasticity

  2018cites this paper
• Central Nervous System Anatomy and Neurochemistry of Sexual Desire

  2018cites this paper
• Activation of 5‐HT2A receptor disrupts rat maternal behavior

  2018influential citation
• Executive function in teen and adult women: Association with maternal status and early adversity

  2018cites this paper
• Altered neural connectivity in adult female rats exposed to early life social stress

  2017cites this paper
• Dopamine, Noradrenaline and Differences in Sexual Behavior between Roman High and Low Avoidance Male Rats: A Microdialysis Study in the Medial Prefrontal Cortex

  2017influential citation
• Maternal Executive Functioning as a Mechanism in the Intergenerational Transmission of Parenting: Preliminary Evidence

  2017cites this paper
• Thinking and doing: the effects of dopamine and oxytocin genes and executive function on mothering behaviours

  2017cites this paper
• Reduced Lordosis and Enhanced Aggression in Paced and Non-Paced Mating in Diabetic Female Rats.

  2017cites this paper
• Prepubertal ovariectomy modulates paced mating behavior but not sexual preference or conditioned place preference for mating in female rats.

  2017cites this paper
• Mothers with substance addictions show reduced reward responses when viewing their own infant's face

  2017cites this paper
• Effects of Jiaotaiwan on depressive-like behavior in mice after lipopolysaccharide administration

  2017cites this paper
• The medial frontal cortex contributes to but does not organize rat exploratory behavior.

  2016cites this paper
• Environmental influences on the female epigenome and behavior

  2016cites this paper
• Observing videos of a baby crying or smiling induces similar, but not identical, electroencephalographic responses in biological and adoptive mothers.

  2016cites this paper
• Socioeconomic disadvantages and neural sensitivity to infant cry: role of maternal distress.

  2016cites this paper
• Behavioral, pharmacological and neuroanatomical analysis of serotonin 2C receptor agonism on maternal behavior in rats.

  2016influential citation
• The maternal brain under stress: Consequences for adaptive peripartum plasticity and its potential functional implications.

  2016cites this paper
• Neuroanatomical and neurochemical basis of parenting: Dynamic coordination of motivational, affective and cognitive processes.

  2016cites this paper
• La importancia del vínculo en la infancia: entre el psicoanálisis y la neurobiología

  2016cites this paper
• Accès à la parentalité des femmes souffrant d'un trouble de la personnalité de type borderline – interactions précoces et attachement : une revue non systématique de la littérature

  2016cites this paper
• Pre-reproductive maternal enrichment influences rat maternal care and offspring developmental trajectories: behavioral performances and neuroplasticity correlates

  2015cites this paper
• Interaction does Count: A Cross-Fostering Study on Transgenerational Effects of Pre-reproductive Maternal Enrichment

  2015cites this paper
• Attachment and parental reflective functioning features in ADHD: enhancing the knowledge on parenting characteristics

  2015cites this paper
• Chapter 1 – An Introduction to Neural Systems

  2015cites this paper
• Affective, cognitive, and motivational processes of maternal care.

  2015cites this paper
• Female Sexual Behavior

  2015cites this paper
• Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.

  2015cites this paper
• Common and divergent psychobiological mechanisms underlying maternal behaviors in non-human and human mammals.

  2015cites this paper
• Dysfonctionnements préfrontaux et pharmacothérapies dans des modèles murins de maladies spychiatriques

  2015cites this paper
• Chapter 51 – Parenting Behavior

  2015cites this paper
• Intergenerational transmission of self-regulation: A multidisciplinary review and integrative conceptual framework.

  2015cites this paper
• Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain.

  2015cites this paper
• Propagation of maternal behavior across generations is associated with changes in non-maternal cognitive and behavioral processes.

  2015cites this paper
• Effects of perinatal undernutrition on the basilar dendritic arbor of the anterior cingulate pyramidal neurons in lactating dams.

  2015influential citation
• The effects of chronic fluoxetine treatment following injury of medial frontal cortex in mice.

  2015cites this paper
• Chronic Gestational Stress Leads to Depressive-Like Behavior and Compromises Medial Prefrontal Cortex Structure and Function during the Postpartum Period

  2014cites this paper
• Gestational stress induces persistent depressive‐like behavior and structural modifications within the postpartum nucleus accumbens

  2014cites this paper
• Medial prefrontal cortex: genes linked to bipolar disorder and schizophrenia have altered expression in the highly social maternal phenotype

  2014influential citation
• Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats.

  2014cites this paper
• Neural plasticity in fathers of human infants

  2014cites this paper
• Oxytocin in the medial prefrontal cortex regulates maternal care, maternal aggression and anxiety during the postpartum period

  2014influential citation
• Cognition of Parenting: The effect of biological factors and cognitive processes and their interaction on adult responsiveness to baby signals

  2013cites this paper
• Effects of Oxytocin in the Medial Prefrontal Cortex: Anxiety, Maternal Care, and Maternal Aggression

  2013influential citation
• Circadian Influences on Brain Damage, Regeneration, and Neurogenesis

  2013cites this paper
• Brain region-specific transcriptomic markers of serotonin-1A receptor agonist action mediating sexual rejection and aggression in female marmoset monkeys.

  2013cites this paper
• Altered bold fMRI response toward survival-pertinent stimuli in the early postpartum dam

  2013cites this paper
• Flexibility and adaptation of the neural substrate that supports maternal behavior in mammals.

  2013cites this paper
• A moderated transactional link between child behavioral problems and parenting: A longitudinal- and behavioral- genetic study

  2013cites this paper
• eview lexibility and adaptation of the neural substrate that supports maternal ehavior in mammals

  2013influential citation
• New theoretical and experimental approaches on maternal motivation in mammals.

  2013influential citation
• Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets

  2012cites this paper
• Maternal early life experiences and parenting: the mediating role of cortisol and executive function.

  2012cites this paper