Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Molecular Microbiology

• Publication date

  1995-07-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1365-2958.1995.mmi_17020333.xPMID 7494482
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterisation of the yenI/yenR locus from Yersinia enterocolitica mediating the synthesis of two N‐acylhomoserine lactone signal molecules

  1995cited by this paper
• The bacterial ‘enigma’: cracking the code of cell–cell communication

  1995cited by this paper
• Carbapenem antibiotic production in Erwinia carotovora is regulated by CarR, a homologue of the LuxR transcriptional activator.

  1995cited by this paper
• Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa.

  1995cited by this paper
• Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.

  1994cited by this paper
• Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa

  1994cited by this paper
• Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84 is regulated by PhzR in response to cell density

  1994cited by this paper
• Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators

  1994cited by this paper
• Gram-negative bacterial communication by N-acyl homoserine lactones: a universal language?

  1994cited by this paper
• Extracellular protease and phospholipase C are controlled by the global regulatory gene gacA in the biocontrol strain Pseudomonas fluorescens CHA0.

  1994cited by this paper
• Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa

  1994cited by this paper
• A LuxR-LuxI type regulatory system activates Agrobacterium Ti plasmid conjugal transfer in the presence of a plant tumor metabolite

  1994cited by this paper
• Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication.

  1993cited by this paper
• Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction

  1993cited by this paper
• Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones

  1993cited by this paper
• LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression

  1993cited by this paper
• Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone.

  1993cited by this paper
• A small diffusible signal molecule is responsible for the global control of virulence and exoenzyme production in the plant pathogen Erwinia carotovora.

  1993cited by this paper
• The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.

  1993cited by this paper
• A novel strategy for the isolation of luxl homologues: evidence for the widespread distribution of a LuxR:Luxl superfamily in enteric bacteria

  1993cited by this paper
• Molecular characterization and regulation of the rhizosphere-expressed genes rhiABCR that can influence nodulation by Rhizobium leguminosarum biovar viciae

  1992cited by this paper
• Small molecule-mediated density-dependent control of gene expression in prokaryotes: bioluminescence and the biosynthesis of carbapenem antibiotics.

  1992cited by this paper
• Global control in Pseudomonas fluorescens mediating antibiotic synthesis and suppression of black root rot of tobacco.

  1992cited by this paper
• Genetic dissection of DNA binding and luminescence gene activation by the Vibrio fischeri LuxR protein

  1992cited by this paper
• Role of elastase as a virulence factor in experimental Pseudomonas aeruginosa infection in mice.

  1992cited by this paper
• A general role for the lux autoinducer in bacterial cell signalling: control of antibiotic biosynthesis in Erwinia.

  1992cited by this paper
• N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora.

  1992cited by this paper
• Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defenses, and demonstration of a manganese-cofactored superoxide dismutase

  1992cited by this paper
• Molecular biology of bacterial bioluminescence.

  1991cited by this paper
• Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression

  1991influential reference
• A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants.

  1991cited by this paper
• A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli.

  1991cited by this paper
• New method for detecting rhamnolipids excreted by Pseudomonas species during growth on mineral agar

  1991cited by this paper
• Escherichia-Pseudomonas shuttle vectors derived from pUC18/19.

  1991cited by this paper
• Cloning of the Pseudomonas aeruginosa alkaline protease gene and secretion of the protease into the medium by Escherichia coli

  1990cited by this paper
• Critical regions of the Vibrio fischeri luxR protein defined by mutational analysis

  1990cited by this paper
• Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: identification of the autoinducer-binding region of the LuxR protein from Vibrio fischeri ATCC 7744

  1990cited by this paper
• Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications

  1990cited by this paper
• Expression patterns of genes encoding elastase and controlling mucoidy: co‐ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis

  1990cited by this paper
• Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria

  1990cited by this paper
• Cloning of xcp genes located at the 55 min region of the chromosome and involved in protein secretion in Pseudomonas aeruginosa

  1989cited by this paper
• Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744.

  1989cited by this paper
• Transformation of Pseudomonas aeruginosa by electroporation.

  1989cited by this paper
• Mutations in the hemolytic-phospholipase C operon result in decreased virulence of Pseudomonas aeruginosa PAO1 grown under phosphate-limiting conditions

  1989cited by this paper
• Interactions of Pseudomonas aeruginosa proteases with the cells of the immune system.

  1989cited by this paper
• Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene

  1988cited by this paper
• Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence.

  1987cited by this paper
• Nucleotide sequence and expression of clcD, a plasmid-borne dienelactone hydrolase gene from Pseudomonas sp. strain B13

  1987cited by this paper
• The contribution of exoproducts to virulence of Pseudomonas aeruginosa.

  1986cited by this paper
• The influence of environment on envelope properties affecting survival of bacteria in infections.

  1985cited by this paper
• A comprehensive set of sequence analysis programs for the VAX

  1984cited by this paper
• Effect of substrate on the regulation of exoprotease production by Pseudomonas aeruginosa ATCC 10145.

  1983cited by this paper
• Method for Rapid Detection of Cyanogenic Bacteria

  1983cited by this paper
• Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants.

  1982cited by this paper
• Influence of Iron on Yields of Extracellular Products in Pseudomonas aeruginosa Cultures

  1979cited by this paper
• Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans.

  1979cited by this paper
• Electrophoretic resolution of the ‘major outer membrane protein’ of Escherichia coli K12 into four bands

  1975cited by this paper

• Volatile compounds as bacterial communication signals: State of art, limitations and future perspectives.

  2026cites this paper
• RmmLII, a novel marine-derived N-acyl homoserine lactonase from Tritonibacter mobilis

  2025cites this paper
• Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus

  2025cites this paper
• Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication

  2025cites this paper
• Integrated analysis of electrical stimulation effects on Pseudomonas aeruginosa PAO1 inoculated denitrifying community: targeted and untargeted metabolomic analysis of phenazine biosynthesis and quorum sensing

  2025cites this paper
• Effect of photodynamic therapy with imipenem and gentamicin-derived carbon dots on the expression of quorum sensing and virulence genes in Pseudomonas aeruginosa

  2025cites this paper
• Pseudomonas aeruginosa Quorum Signals; Associations with Virulence, and Impact of Therapeutic Gamma Radiation Doses

  2025cites this paper
• The H-NS homologues MvaT and MvaU repress CRISPR-Cas in Pseudomonas aeruginosa.

  2025cites this paper
• The road less traveled: Unexplored targets in the quest for antibiotics against Pseudomonas aeruginosa.

  2025cites this paper
• Microbial phenazines: biosynthesis, structural diversity, evolution, regulation, and biological significance

  2025cites this paper
• Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia

  2025cites this paper
• Modularized Design and Construction of Tunable Microbial Consortia with Flexible Topologies

  2024cites this paper
• 2,3-Dimethoxycinnamic Acid from a Marine Actinomycete, a Promising Quorum Sensing Inhibitor in Chromobacterium violaceum

  2024cites this paper
• Cyclic Diguanylate G-Quadruplex Inducer-Quorum Sensing Inhibitor Hybrids as Bifunctional Anti-biofilm and Anti-virulence Agents Against Pseudomonas aeruginosa.

  2024cites this paper
• Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia

  2024cites this paper
• The battle within: how Pseudomonas aeruginosa uses host-pathogen interactions to infect the human lung

  2024cites this paper
• Rational engineering S1' substrate binding pocket to enhance substrate specificity and catalytic activity of thermal-stable keratinase for efficient keratin degradation.

  2024cites this paper
• N2O recovery from wastewater and flue gas via microbial denitrification: Processes and mechanisms.

  2024cites this paper
• Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine lactone and PqsE

  2023cites this paper
• Effects of co-selection of antibiotic-resistance and metal-resistance genes on antibiotic-resistance potency of environmental bacteria and related ecological risk factors.

  2023cites this paper
• Quorum Sensing in Halorubrum saccharovorum Facilitates Cross-Domain Signaling between Archaea and Bacteria

  2023cites this paper
• Modeling downstream impact of a quorum sensing system of Pseudomonas aeruginosa in colony spreading

  2023cites this paper
• Listening to enteric bacteria from the perspective of antibiotic alternatives in animal husbandry

  2023cites this paper
• Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in Pseudomonas aeruginosa

  2023cites this paper
• A periplasmic phospholipase that maintains outer membrane lipid asymmetry in Pseudomonas aeruginosa

  2023cites this paper
• Antimicrobial Weapons of Pseudomonas aeruginosa.

  2022cites this paper
• The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa

  2022cites this paper
• A Geneticist Transcribing the Chemical Language of Bacteria.

  2022cites this paper
• Cucurbit[7]uril: Synthesis and quenching the quorum sensing in bacteria

  2022cites this paper
• Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation.

  2022cites this paper
• Molecular Relationships in Biofilm Formation and the Biosynthesis of Exoproducts in Pseudoalteromonas spp.

  2022cites this paper
• Transcriptional Profiling of Pseudomonas aeruginosa Infections.

  2022cites this paper
• Impact of Quorum Sensing and Tropodithietic Acid Production on the Exometabolome of Phaeobacter inhibens

  2022cites this paper
• Detection of Quorum Sensing Genes of Pseudomonas aeruginosa Isolated from Different Areas in Iraq

  2022cites this paper
• Early activated quorum sensing enhanced a nosZ-deficient strain of Pseudomonas aeruginosa for stably recovering nitrous oxide from incineration leachate in microbial electrolysis cell.

  2022cites this paper
• The influence of non-inhibitory concentrations of purified pyocin S2 on Pseudomonas aeruginosa isolates

  2021cites this paper
• Pseudomonas chlororaphis PA23 metabolites protect against protozoan grazing by the predator Acanthamoeba castellanii

  2021cites this paper
• Cysteamine Inhibits Glycine Utilisation and Disrupts Virulence in Pseudomonas aeruginosa

  2021cites this paper
• Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa lasI Quorum-Sensing Mutant

  2021cites this paper
• Summary of Experimental Results

  2020cites this paper
• Design and synthesis of aryl-substituted pyrrolidone derivatives as quorum sensing inhibitors.

  2020cites this paper
• Genome-Wide Identification of Dickeya solani Transcriptional Units Up-Regulated in Response to Plant Tissues From a Crop-Host Solanum tuberosum and a Weed-Host Solanum dulcamara

  2020cites this paper
• Microbial Communication: Mathematical Modeling, Synthetic Biology and the Role of Noise

  2020cites this paper
• Targeting virulence factors as an antimicrobial approach: Pigment inhibitors

  2020cites this paper
• Bacterial chatter in chronic wound infections

  2020cites this paper
• Review of Potential Pseudomonas Weaponry, Relevant to the Pseudomonas–Aspergillus Interplay, for the Mycology Community

  2020cites this paper
• Alternative approaches to treat bacterial infections: targeting quorum-sensing

  2020cites this paper
• Identification of a Second Type of AHL-lactonase from Rhodococcus sp. BH4, belonging to the α/β Hydrolase Superfamily

  2020cites this paper
• Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus

  2020cites this paper
• Spatiotemporal Distribution of Pseudomonas aeruginosa Alkyl Quinolones under Metabolic and Competitive Stress

  2020cites this paper
• Phenylacetyl-CoA, not phenylacetic acid, attenuates CepIR-regulated virulence in Burkholderia cenocepacia

  2019cites this paper
• Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia

  2019cites this paper
• Sub-lethal antimicrobial photodynamic inactivation: an in vitro study on quorum sensing-controlled gene expression of Pseudomonas aeruginosa biofilm formation

  2019cites this paper
• Isonitrile-functionalized tyrosine modulates swarming motility and quorum sensing in Pseudomonas aeruginosa.

  2019cites this paper
• LasR might act as an intermediate in overproduction of phenazines in the absence of RpoS in Pseudomonas aeruginosa.

  2019cites this paper
• A novel heterologous expression strategy for the quorum-quenching enzyme MomL in Lysobacter enzymogenes to the inhibit pathogenicity of Pectobacterium

  2019cites this paper
• A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in Streptomyces hygrospinosus var. beijingensis

  2019cites this paper
• Regulatory Effect of DNA Topoisomerase I on T3SS Activity, Antibiotic Susceptibility and Quorum- Sensing-Independent Pyocyanin Synthesis in Pseudomonas aeruginosa

  2019cites this paper
• Inhibition of biofilm formation, quorum sensing activity and molecular docking study of isolated 3, 5, 7-Trihydroxyflavone from Alstonia scholaris leaf against P.aeruginosa.

  2019cites this paper
• Small Is Mighty-Chemical Communication Systems in Pseudomonas Aeruginosa.

  2019cites this paper
• Loci Identification of a N-acyl Homoserine Lactone Type Quorum Sensing System and a New LysR-type Transcriptional Regulator Associated with Antimicrobial Activity and Swarming in Burkholderia Gladioli UAPS07070

  2019cites this paper
• An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation

  2019cites this paper
• β-Sitosterol derived compound from onion husks non-polar fraction reduces quorum sensing controlled virulence and biofilm production

  2019influential citation
• Characterization of quorum sensing genes and N-acyl homoserine lactones in Citrobacter amalonaticus strain YG6.

  2019cites this paper
• Effect of Andrographolide and Its Analogs on Bacterial Infection: A Review

  2019cites this paper
• Quorum machinery: Effect of the las system in rhl regulation of P. aeruginosa

  2019cites this paper
• LasR LBD L130F:3OC14HSL complex

  2019cites this paper
• Convergent gain and loss of genomic islands drive lifestyle changes in plant-associated Pseudomonas

  2019cites this paper
• Synthèse de conjugués glycoclusters-sidérophores pour augmenter l’activité anti-infectieuse contre Pseudomonas aeruginosa

  2019cites this paper
• phz1 contributes much more to phenazine‐1‐carboxylic acid biosynthesis than phz2 in Pseudomonas aeruginosa rpoS mutant

  2019cites this paper
• Anti-biofilm effect of novel thiazole acid analogs against Pseudomonas aeruginosa through IQS pathways.

  2018cites this paper
• Structural determinants driving homoserine lactone ligand selection in the Pseudomonas aeruginosa LasR quorum-sensing receptor

  2018cites this paper
• Isolation and Characterization of N-acyl Homoserine Lactone-Producing Bacteria From Cattle Rumen and Swine Intestines

  2018cites this paper
• Convergent gain and loss of genomic islands drives lifestyle changes in plant-associated bacteria

  2018cites this paper
• Identification of wysPII as an Activator of Morphological Development in Streptomyces albulus CK-15

  2018cites this paper
• Characterization of diverse homoserine lactone synthases in Escherichia coli

  2018cites this paper
• Dual-Edged Character of Quorum Sensing Signaling Molecules in Microbial Extracellular Electron Transfer

  2018cites this paper
• Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa

  2018cites this paper
• The Pseudomonas aeruginosa PrrF1 and PrrF2 Small Regulatory RNAs Promote 2-Alkyl-4-Quinolone Production through Redundant Regulation of the antR mRNA

  2018cites this paper
• The Pseudomonas aeruginosa LasR quorum-sensing receptor balances ligand selectivity and sensitivity

  2018cites this paper
• Antibiotic Resistance and Cell-Wall Recycling in Pseudomonas aeruginosa

  2018cites this paper
• Pseudomonas

  2018cites this paper
• The synthesis and biological evaluation of a library of autoinducer-antibiotic conjugates

  2018cites this paper
• Host suppression of quorum sensing during catheter-associated urinary tract infections

  2018cites this paper
• Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression

  2018cites this paper
• Quorum‐sensing regulator RhlR but not its autoinducer RhlI enables Pseudomonas to evade opsonization

  2018cites this paper
• Quorum sensing signal production by sponge-associated bacteria isolated from the Red Sea, Egypt

  2017cites this paper
• Pulse Generation in the Quorum Machinery of Pseudomonas aeruginosa

  2017cites this paper
• The rapid in vivo evolution of Pseudomonas aeruginosa in ventilator-associated pneumonia patients leads to attenuated virulence

  2017cites this paper
• Detection and Control of Indoor Airborne Pathogenic Bacteria by Biosensors Based on Quorum Sensing Chemical Language: Bio-Tools, Connectivity Apps and Intelligent Buildings

  2017cites this paper
• The Role of Quorum Sensing in Bacterial Colony Dynamics

  2017cites this paper
• Pseudomonas aeruginosa Biofilm, a Programmed Bacterial Life for Fitness.

  2017cites this paper
• Suppressing the CRISPR/Cas adaptive immune system in bacterial infections

  2017cites this paper
• The small RNA ReaL: a novel regulatory element embedded in the Pseudomonas aeruginosa quorum sensing networks

  2017cites this paper
• The Role of Bacterial Biofi lms in Chronic Infections

  2017cites this paper
• Onion Peel Ethylacetate Fraction and Its Derived Constituent Quercetin 4′-O-β-D Glucopyranoside Attenuates Quorum Sensing Regulated Virulence and Biofilm Formation

  2017cites this paper
• RhlR, but not RhlI, allows P. aeruginosa bacteria to evade Drosophila Tep4-mediated opsonization

  2017cites this paper
• Impacts of nanomaterials on social behaviour of microorganisms

  2017cites this paper
• Characterisation of explosive cell lysis in Pseudomonas aeruginosa

  2017cites this paper
• Investigating the genetic basis of preservative resistance in an industrial Pseudomonas aeruginosa strain

  2017cites this paper