Gender Differences in Spinal Cord Injury Are Not Estrogen-Dependent

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Neurotrauma

• Publication date

  2007-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/neu.2006.0167PMID 17402853
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 17β-Estradiol Is Protective in Spinal Cord Injury in Post- and Pre-Menopausal Rats

  2006influential reference
• Gender-related differences in recovery of locomotor function after spinal cord injury in mice

  2006influential reference
• Lack of a Gender Difference in Post-Traumatic Neurodegeneration in the Mouse Controlled Cortical Impact Injury Model

  2005influential reference
• An Adult Rat Spinal Cord Contusion Model of Sensory Axon Degeneration: The Estrus Cycle or a Preconditioning Lesion Do Not Affect Outcome

  2005cited by this paper
• Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice.

  2005cited by this paper
• The Effects of Gender on Clinical and Neurological Outcomes after Acute Cervical Spinal Cord Injury

  2005influential reference
• Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats

  2005influential reference
• Systemic Administration of 17β-Estradiol Reduces Apoptotic Cell Death and Improves Functional Recovery following Traumatic Spinal Cord Injury in Rats

  2004influential reference
• Sex differences in injury severity and outcome measures after traumatic brain injury.

  2004influential reference
• Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats.

  2004influential reference
• Gender and age effects on outcome after pediatric traumatic brain injury*

  2004influential reference
• Effects of gender on neurologic and functional recovery after spinal cord injury.

  2004influential reference
• Estrogens in the nervous system: mechanisms and nonreproductive functions.

  2004cited by this paper
• Experimental Modeling of Spinal Cord Injury: Characterization of a Force-Defined Injury Device

  2003cited by this paper
• Acute neurosurgical management of traumatic brain injury and spinal cord injury

  2003influential reference
• Gender differences in drug effects: implications for anesthesiologists

  2003cited by this paper
• Estrogen as a Neuroprotective Agent in the Treatment of Spinal Cord Injury

  2003influential reference
• Estrogen and progesterone as neuroprotective agents in the treatment of acute brain injuries

  2003cited by this paper
• Creatine Diet Supplement for Spinal Cord Injury: Influences on Functional Recovery and Tissue Sparing in Rats

  2003cited by this paper
• Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity?

  2002influential reference
• Age differentially influences estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) gene expression in specific regions of the rat brain.

  2002cited by this paper
• A Statistical Method for Analyzing Rating Scale Data: The BBB Locomotor Score

  2002influential reference
• Age differentially influences estrogen receptor α (ERα) and estrogen receptor β (ERβ) gene expression in specific regions of the rat brain

  2002cited by this paper
• Estrogen Prevents the Lipopolysaccharide-Induced Inflammatory Response in Microglia

  2001cited by this paper
• Cyclosporin A Treatment Following Spinal Cord Injury to the Rat: Behavioral Effects and Stereological Assessment of Tissue Sparing

  2001cited by this paper
• Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions

  2001cited by this paper
• Gender-related differences in acute rehabilitation lengths of stay, charges, and functional outcomes for a matched sample with spinal cord injury: a multicenter investigation.

  2001cited by this paper
• Do women fare worse: a metaanalysis of gender differences in traumatic brain injury outcome.

  2000influential reference
• Potential neurotoxicity of spinal anesthesia with lidocaine.

  2000cited by this paper
• Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat.

  2000cited by this paper
• Recent demographic and injury trends in people served by the Model Spinal Cord Injury Care Systems.

  1999cited by this paper
• Female TBI patients recover better than males.

  1998cited by this paper
• Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures.

  1997cited by this paper
• Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection.

  1996cited by this paper
• A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

  1995influential reference
• Epidemiology of traumatic spinal cord injury and acute hospitalization and rehabilitation charges for spinal cord injuries in Oklahoma, 1988-1990.

  1994cited by this paper
• Changes in epidemiology of acute spinal cord injury for 1947-1981.

  1994cited by this paper
• Changes in epidemiology of acute spinal cord injury from 1947 to 1981.

  1993cited by this paper
• Methylprednisolone and neurological function 1 year after spinal cord injury. Results of the National Acute Spinal Cord Injury Study.

  1985cited by this paper
• Effects of estradiol and progesterone on plasma gonadotropins, prolactin, and LHRH in specific brain areas of ovariectomized rats.

  1981cited by this paper

• Hormonal regulatory networks in spinal cord injury: mechanistic insights, crosstalk, and therapeutic innovations

  2025cites this paper
• Integrating sensitive motor tasks with histopathology detects sex differences in recovery after spinal cord injury.

  2025cites this paper
• Sex and Strain-Specific Variations in Motor Recovery Following Compression Spinal Cord Injury: Comparison of Sprague-Dawley and Wistar Rats

  2025cites this paper
• Sex dimorphisms in coagulation: Implications in trauma‐induced coagulopathy and trauma resuscitation

  2024cites this paper
• Depression-like behavior is associated with deficits in cognition and hippocampal neurogenesis in a subset of spinally contused male, but not female, rats.

  2024cites this paper
• Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons

  2024cites this paper
• Metformin Improves Functional Outcomes, Activates Neural Precursor Cells, and Modulates Microglia in a Sex-Dependent Manner After Spinal Cord Injury

  2023cites this paper
• The Limited Effects of Estradiol Administration Immediately after Spinal Cord Injury.

  2023cites this paper
• Tibolone Improves Locomotor Function in a Rat Model of Spinal Cord Injury by Modulating Apoptosis and Autophagy

  2023cites this paper
• The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury

  2023cites this paper
• The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury

  2022cites this paper
• Noxious Stimulation Induces Acute Hemorrhage and Impairs Long-Term Recovery after Spinal Cord Injury (SCI) in Female Rats: Evidence Estrous Cycle May Have a Modulatory Effect

  2022cites this paper
• Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury

  2022cites this paper
• Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms

  2021influential citation
• Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain.

  2021cites this paper
• The Pathophysiology of Osteoporosis after Spinal Cord Injury

  2021cites this paper
• Pericytes improve locomotor recovery after spinal cord injury in male and female neonatal rats

  2020cites this paper
• Effect of Sex on Motor Function, Lesion Size, and Neuropathic Pain after Contusion Spinal Cord Injury in Mice

  2020cites this paper
• Sex-Related Differences in Anxiety and Functional Recovery after Spinal Cord Injury in Mice

  2020cites this paper
• Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury

  2020cites this paper
• Divergent Findings in Brain Reorganization After Spinal Cord Injury: A Review

  2020cites this paper
• Myristoylated alanine‐rich C‐kinase substrate effector domain peptide improves sex‐specific recovery and axonal regrowth after spinal cord injury

  2020cites this paper
• Spinal Cord Injury in Rats Dysregulates Diurnal Rhythms of Fecal Output and Liver Metabolic Indicators

  2019cites this paper
• Age and sex differences in the pathophysiology of acute CNS injury.

  2019cites this paper
• Continuous tamoxifen delivery improves locomotor recovery 6 h after spinal cord injury by neuronal and glial mechanisms in male rats

  2018cites this paper
• Protective Effects of Estradiol and Dihydrotestosterone following Spinal Cord Injury

  2018cites this paper
• Targeting axonal degeneration and demyelination using combination administration of 17β‐estradiol and Schwann cells in the rat model of spinal cord injury

  2018cites this paper
• Neurological Aspects of Spinal Cord Injury

  2017cites this paper
• The Current Status of Neuroprotection for Spinal Cord Injury

  2017cites this paper
• Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage

  2017cites this paper
• Molecular mechanisms of estrogen for neuroprotection in spinal cord injury and traumatic brain injury

  2016cites this paper
• Influence of Sexuality in Functional Recovery after Spinal Cord Injury in Rats.

  2016cites this paper
• Use of the CatWalk Gait Device to Assess Differences in Locomotion between Genders in Rats Inherently and following Spinal Cord Injury

  2016cites this paper
• Melatonin for Spinal Cord Injury in Animal Models: A Systematic Review and Network Meta-Analysis

  2016cites this paper
• miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair

  2016cites this paper
• The Fischer 344 spinal cord contusion model and effects of cyclosporin-A on the model

  2016cites this paper
• Does being female provide a neuroprotective advantage following spinal cord injury?

  2015influential citation
• Female Rats Demonstrate Improved Locomotor Recovery and Greater Preservation of White and Gray Matter after Traumatic Spinal Cord Injury Compared to Males

  2015cites this paper
• Characterization of recovery, repair, and inflammatory processes following contusion spinal cord injury in old female rats: is age a limitation?

  2014cites this paper
• Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha.

  2014influential citation
• The Sex of the Cell Dictates its Response

  2014cites this paper
• Sex steroids and neuroprotection in spinal cord injury: a review of preclinical investigations.

  2014cites this paper
• Effect of Gender on Recovery After Spinal Cord Injury

  2013cites this paper
• Risk of death after hospital discharge with traumatic spinal cord injury: a population-based analysis, 1998-2009.

  2013cites this paper
• Gender and Age Interact to Affect Early Outcome after Intracerebral Hemorrhage

  2013cites this paper
• Limiting spinal cord injury by pharmacological intervention.

  2012cites this paper
• Postinjury administration of 17β‐estradiol induces protection in the gray and white matter with associated functional recovery after cervical spinal cord injury in male rats

  2012cites this paper
• Female sex is not associated with improved rates of ROSC or short term survival following prolonged porcine ventricular fibrillation.

  2012cites this paper
• Neuroprotective effects of testosterone on motoneuron and muscle morphology following spinal cord injury

  2012cites this paper
• Spinal cord hemisection delays the rodent estrous cycle

  2011cites this paper
• A Systematic Review of Non-Invasive Pharmacologic Neuroprotective Treatments for Acute Spinal Cord Injury

  2011cites this paper
• Low dose Estrogen Prevents Neuronal Degeneration and Microglial Reactivity in an Acute Model of Spinal Cord Injury: Effect of Dosing, Route of Administration, and Therapy Delay

  2011influential citation
• Neuroprotective Drugs in Traumatic CNS Injury

  2010cites this paper
• Sex and hormonal variations in the development of at-level allodynia in a rat chronic spinal cord injury model.

  2010cites this paper
• Melatonin-analog, beta-methyl-6-chloromelatonin, supplementation in spinal cord injury.

  2010cites this paper
• Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats

  2010cites this paper
• Effects of Chronic Restraint Stress and 17-β-Estradiol Replacement on Oxidative Stress in the Spinal Cord of Ovariectomized Female Rats

  2010cites this paper
• Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats

  2010cites this paper
• Effect of Endogenous Androgens on 17β-Estradiol-Mediated Protection after Spinal Cord Injury in Male Rats

  2010cites this paper
• De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

  2009cites this paper
• Exacerbation of spinal cord injury due to static compression occurring early after onset.

  2009cites this paper
• Muscle after spinal cord injury

  2009cites this paper
• he combination of human neuronal serotonergic cell implants and nvironmental enrichment after contusive SCI improves motor ecovery over each individual strategy

  2008cites this paper
• Estrogen-Induced Bcl-2 Expression after Spinal Cord Injury Is Mediated through Phosphoinositide-3-Kinase/Akt-Dependent CREB Activation

  2008cites this paper
• Methods for behavioral testing of spinal cord injured rats.

  2008cites this paper