Gender-related differences in recovery of locomotor function after spinal cord injury in mice

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Spinal Cord

• Publication date

  2006-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.sc.3101816PMID 16130019
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Systemic Administration of 17β-Estradiol Reduces Apoptotic Cell Death and Improves Functional Recovery following Traumatic Spinal Cord Injury in Rats

  2004cited by this paper
• Aging, gender, and spinal cord injury.

  2004cited by this paper
• A demographic profile of new traumatic spinal cord injuries: change and stability over 30 years.

  2004cited by this paper
• Effects of gender on neurologic and functional recovery after spinal cord injury.

  2004cited by this paper
• Sex-related differences of rehabilitation outcomes of spinal cord lesion patients

  2004cited by this paper
• Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats.

  2004cited by this paper
• Factors associated with improved neurologic outcomes in patients with incomplete tetraplegia.

  2003cited by this paper
• Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity?

  2002cited by this paper
• Estrogen and Bcl-2: Gene Induction and Effect of Transgene in Experimental Stroke

  2001cited by this paper
• White matter preservation after spinal cord injury in ICAM-1/P-selectin-deficient mice

  2001cited by this paper
• Improved Recovery After Spinal Cord Injury in Neuronal Nitric Oxide Synthase-Deficient Mice But not in TNF-α-Deficient Mice

  2001cited by this paper
• Neuroprotection of S(+) ketamine isomer in global forebrain ischemia.

  2001cited by this paper
• Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse.

  2001cited by this paper
• A force-plate actometer for quantitating rodent behaviors: illustrative data on locomotion, rotation, spatial patterning, stereotypies, and tremor.

  2001cited by this paper
• Review of Current Evidence for Apoptosis After Spinal Cord Injury

  2000cited by this paper
• Estrogen-Related Gender Difference in Survival Rate and Cortical Blood Flow After Impact-Acceleration Head Injury in Rats

  2000cited by this paper
• Spinal cord compression injury in the mouse: presentation of a model including assessment of motor dysfunction

  2000cited by this paper
• Spinal Cord Injury in ICAM-1–Deficient Mice: Assessment of Functional and Histopathological Outcome

  2000cited by this paper
• Acute activation of Maxi-K channels (hSlo) by estradiol binding to the beta subunit.

  1999cited by this paper
• Improved recovery after spinal cord trauma in ICAM-1 and P-selectin knockout mice.

  1999cited by this paper
• Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors

  1999cited by this paper
• Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

  1999cited by this paper
• Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord

  1999cited by this paper
• Estrogen Reduces Leukocyte Adhesion in the Cerebral Circulation of Female Rats

  1999cited by this paper
• Modulation of Bcl‐2 expression: a potential component of estrogen protection in NT2 neurons

  1998cited by this paper
• Gender-linked brain injury in experimental stroke

  1998cited by this paper
• Gender-linked brain injury in experimental stroke.

  1998cited by this paper
• Apoptosis in Cellular Compartments of Rat Spinal Cord After Severe Contusion Injury

  1998cited by this paper
• Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures.

  1997cited by this paper
• 17 beta-Estradiol attenuates endotoxin-induced excessive nitric oxide production in ovariectomized rats in vivo.

  1997cited by this paper
• Effects of Moderate Hypothermia on Extracellular Lactic Acid and Amino Acids after Severe Compression Injury of Rat Spinal Cord

  1997cited by this paper
• Apoptosis and Expression of Bcl‐2 after Compression Trauma to Rat Spinal Cord

  1996cited by this paper
• The vascular protective effects of estrogen

  1996cited by this paper
• Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection.

  1996cited by this paper
• Changes of Extracellular Levels of Amino Acids after Graded Compression Trauma to the Spinal Cord: An Experimental Study in the Rat Using Microdialysis

  1996cited by this paper
• Changes of β-Amyloid Precursor Protein after Compression Trauma to the Spinal Cord: An Experimental Study in the Rat Using Immunohistochemistry

  1995cited by this paper
• Gender-specific impairment on Morris water maze task after entorhinal cortex lesion.

  1993cited by this paper
• The European Stroke Prevention Study

  1991cited by this paper
• Sex Differences in Postischemic Neuronal Necrosis in Gerbils

  1991cited by this paper
• The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics.

  1986cited by this paper
• Sex-related factors in acute hypoxia survival in one strain of mice.

  1984cited by this paper
• Carotid Ligation in Gerbils Influence of Age, Sex, and Gonads

  1977cited by this paper

• Prognostic influences and prediction model construction for traumatic cervical spinal cord injury

  2026cites this paper
• Tibolone Improves Motor Recovery and Regulates Neuroinflammation and Gliosis in a Model of Traumatic Spinal Cord Injury

  2025cites this paper
• Integrating sensitive motor tasks with histopathology detects sex differences in recovery after spinal cord injury.

  2025cites this paper
• Sex-Related Differences in Functional and Neurological Outcomes of Spinal Cord Injury.

  2025cites this paper
• Serum evaluation of NFL correlates with histological identification of degenerating axons.

  2025cites this paper
• Unbiased Quantification of Persistent Postural and Motor Deficits Following Spinal Cord Injury in Mice

  2025cites this paper
• A brain-accessible peptide modulates stroke inflammatory response and neurotoxicity by targeting BDNF-receptor TrkB-T1 specific interactome

  2025cites this paper
• The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression

  2025cites this paper
• Sex-related disparities in mobility, sensory function, and psychological outcomes in Wistar and Sprague-Dawley rats following spinal cord injury.

  2025cites this paper
• Neuromodulation with transcranial direct current stimulation contributes to motor function recovery via microglia in spinal cord injury

  2024cites this paper
• Dynamic development of microglia and macrophages after spinal cord injury

  2024cites this paper
• Harnessing Artificial Neural Networks for Spinal Cord Injury Prognosis

  2024cites this paper
• Evaluating Sex Steroid Hormone Neuroprotection in Spinal Cord Injury in Animal Models: Is It Promising in the Clinic?

  2024cites this paper
• Sex differences in spontaneous respiratory recovery following chronic C2 hemisection.

  2024cites this paper
• Sex Dependent Disparities in the Central Innate Immune Response after Moderate Spinal Cord Contusion in Rat

  2024cites this paper
• Inner and outer penetrating spinal cord injuries lead to distinct overground walking in mice

  2024cites this paper
• PTEN deletion in spinal pathways via retrograde transduction with AAV-RG enhances forelimb motor recovery after cervical spinal cord injury; Sex differences and late-onset pathophysiologies.

  2023cites this paper
• Myeloid Cell Association with Spinal Cord Injury-Induced Neuropathic Pain and Depressive-like Behaviors in LysM-eGFP Mice.

  2023cites this paper
• Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition

  2023cites this paper
• PTEN deletion in spinal pathways via retrograde transduction with AAV-rg enhances forelimb motor recovery after cervical spinal cord injury; sex differences and late-onset pathophysiologies

  2023cites this paper
• Administration of Tamoxifen Can Regulate Changes in Gene Expression during the Acute Phase of Traumatic Spinal Cord Injury

  2023cites this paper
• Structural validity of the Trunk Assessment Scale for Spinal Cord Injury (TASS) with Rasch analysis for individuals with spinal cord disorders

  2023cites this paper
• Gene expression and locomotor recovery in adult rats with spinal cord injury and plasma-synthesized polypyrrole/iodine application combined with a mixed rehabilitation scheme

  2023cites this paper
• Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model

  2022cites this paper
• Sexual Dimorphism in Lesion Size and Sensorimotor Responses Following Spinal Cord Injury

  2022influential citation
• Potential targets and mechanisms of photobiomodulation for spinal cord injury

  2022cites this paper
• A simple scoring of beam walking performance after spinal cord injury in mice

  2022cites this paper
• Changes in functional independence after inpatient rehabilitation in patients with spinal cord injury: A simultaneous evaluation of prognostic factors

  2022cites this paper
• Nanoformulated Metformin Enhanced the Treatment of Spinal Cord Injury

  2022cites this paper
• Noxious Stimulation Induces Acute Hemorrhage and Impairs Long-Term Recovery after Spinal Cord Injury (SCI) in Female Rats: Evidence Estrous Cycle May Have a Modulatory Effect

  2022cites this paper
• Negative Impact of Sigma-1 Receptor Agonist Treatment on Tissue Integrity and Motor Function Following Spinal Cord Injury

  2021cites this paper
• Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain.

  2021cites this paper
• Extracellular Matrix and Oxidative Stress Following Traumatic Spinal Cord Injury: Physiological and Pathophysiological Roles and Opportunities for Therapeutic Intervention

  2021cites this paper
• The Comparation of Two Instruments for Rat Cervical 2 Hemisection Model

  2021cites this paper
• Detection of locomotion deficit in a post-traumatic syringomyelia rat model using automated gait analysis technique

  2021cites this paper
• Acute inflammatory profiles differ with sex and age after spinal cord injury

  2021cites this paper
• Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice

  2020cites this paper
• Divergent Findings in Brain Reorganization After Spinal Cord Injury: A Review

  2020cites this paper
• Lentiviral Interleukin-10 Gene Therapy Preserves Fine Motor Circuitry and Function After a Cervical Spinal Cord Injury in Male and Female Mice

  2020cites this paper
• Effect of Sex on Motor Function, Lesion Size, and Neuropathic Pain after Contusion Spinal Cord Injury in Mice

  2020cites this paper
• Delayed short-term tamoxifen treatment does not promote remyelination or neuron sparing after spinal cord injury

  2020cites this paper
• Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury

  2020cites this paper
• Intermittent Fasting After Spinal Cord Injury Does Not Improve the Recovery of Baroreflex Regulation in the Rat

  2020cites this paper
• Characterizing Natural Recovery after Traumatic Spinal Cord Injury

  2020cites this paper
• Time-to-treatment window and cross-sex potential of β2-adrenergic receptor-induced mitochondrial biogenesis-mediated recovery after spinal cord injury.

  2020cites this paper
• Proton-sensing receptor GPR132 facilitates migration of astrocytes.

  2020cites this paper
• Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord

  2020cites this paper
• Functional and Histological Gender Comparison of Age-Matched Rats after Moderate Thoracic Contusive Spinal Cord Injury

  2019cites this paper
• Age and sex differences in the pathophysiology of acute CNS injury.

  2019cites this paper
• Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways.

  2019cites this paper
• Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice

  2019cites this paper
• Protective Effects of Estradiol and Dihydrotestosterone following Spinal Cord Injury

  2018cites this paper
• Continuous tamoxifen delivery improves locomotor recovery 6 h after spinal cord injury by neuronal and glial mechanisms in male rats

  2018cites this paper
• A ROLE FOR EPAC1 AND EPAC2 IN NOCICEPTOR HYPEREXCITABILITY AND CHRONIC PAIN AFTER SPINAL CORD INJURY

  2018cites this paper
• Pifithrin‐μ modulates microglial activation and promotes histological recovery following spinal cord injury

  2018cites this paper
• Sex Difference in Oxidative Stress Parameters in Spinal Cord of Rats with Experimental Autoimmune Encephalomyelitis: Relation to Neurological Deficit

  2017cites this paper
• The Current Status of Neuroprotection for Spinal Cord Injury

  2017cites this paper
• Neuroprotective effects of estrogen in CNS injuries: insights from animal models

  2017cites this paper
• Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats.

  2017cites this paper
• The Fischer 344 spinal cord contusion model and effects of cyclosporin-A on the model

  2016cites this paper
• Future directions for using estrogen receptor agonists in the treatment of acute and chronic spinal cord injury

  2016cites this paper
• Astrocytes as a target for neuroprotection: Modulation by progesterone and dehydroepiandrosterone.

  2016cites this paper
• Antibody profiling identifies novel antigenic targets in spinal cord injury patients

  2016cites this paper
• Molecular mechanisms of estrogen for neuroprotection in spinal cord injury and traumatic brain injury

  2016cites this paper
• The demyelination and altered motor performance following electrolytic lesion in the ventrolateral white matter of spinal cord in male rats: benefit of post-injury administration of estradiol

  2016cites this paper
• Use of the CatWalk Gait Device to Assess Differences in Locomotion between Genders in Rats Inherently and following Spinal Cord Injury

  2016cites this paper
• Influence of Sexuality in Functional Recovery after Spinal Cord Injury in Rats.

  2016cites this paper
• Female Rats Demonstrate Improved Locomotor Recovery and Greater Preservation of White and Gray Matter after Traumatic Spinal Cord Injury Compared to Males

  2015cites this paper
• Does being female provide a neuroprotective advantage following spinal cord injury?

  2015influential citation
• Estrogen Influences on Neuromuscular Function in Postmenopausal Women

  2014cites this paper
• Sex steroids and neuroprotection in spinal cord injury: a review of preclinical investigations.

  2014cites this paper
• Novel Multi-System Functional Gains via Task Specific Training in Spinal Cord Injured Male Rats

  2014cites this paper
• Effects of chronic cold exposure on murine central nervous system

  2014cites this paper
• Infertility inMen with Spinal Cord Injury : Research and Treatment

  2014cites this paper
• Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha.

  2014cites this paper
• Effect of Gender on Recovery After Spinal Cord Injury

  2013cites this paper
• Neuroprotective effects of testosterone on motoneuron and muscle morphology following spinal cord injury

  2012cites this paper
• Automated Gait Analysis Following Spinal Cord Injury

  2012cites this paper
• Postinjury administration of 17β‐estradiol induces protection in the gray and white matter with associated functional recovery after cervical spinal cord injury in male rats

  2012cites this paper
• Innate immune responses during neuronal death and regeneration

  2012cites this paper
• Infertility in Men with Spinal Cord Injury: Research and Treatment

  2012cites this paper
• An Approach to Experimental Synaptic Pathology Using Green Fluorescent Protein-Transgenic Mice and Gene Knockout Mice to Show Mitochondrial Permeability Transition Pore-Driven Excitotoxicity in Interneurons and Motoneurons

  2011cites this paper
• Inhibition of Cysteine Proteases in Acute and Chronic Spinal Cord Injury

  2011cites this paper
• Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 b -oestradiol treatment

  2010cites this paper
• Comparison of Immunopathology and Locomotor Recovery in C57BL/6, BUB/BnJ, and NOD-SCID Mice after Contusion Spinal Cord Injury

  2010cites this paper
• Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 beta-oestradiol treatment.

  2010cites this paper
• Development of a simplified spinal cord ischemia model in mice.

  2010cites this paper
• Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves

  2010cites this paper
• Effect of Endogenous Androgens on 17β-Estradiol-Mediated Protection after Spinal Cord Injury in Male Rats

  2010cites this paper
• Muscle after spinal cord injury

  2009cites this paper
• Traumatic spinal cord injury mortality, 1981-1998.

  2009cites this paper
• Estrogen-Induced Bcl-2 Expression after Spinal Cord Injury Is Mediated through Phosphoinositide-3-Kinase/Akt-Dependent CREB Activation

  2008cites this paper
• Ventilation and phrenic output following high cervical spinal hemisection in male vs. female rats.

  2008cites this paper
• Multimodal MRI evaluation of acute mild-contusive injury in mouse spinal cord

  2008cites this paper
• Effects of autoimmunity on recovery of function in adult rats following spinal cord injury.

  2008cites this paper
• Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male rats.

  2008cites this paper
• Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model.

  2007cites this paper
• Longitudinal magnetic resonance imaging of spinal cord injury in mouse: changes in signal patterns associated with the inflammatory response.

  2007cites this paper
• Gender Differences in Spinal Cord Injury Are Not Estrogen-Dependent

  2007influential citation
• Chapter 22 – Role of Antioxidant Activity of Estrogens in their Potent Neuroprotection

  2007cites this paper