Beneficial effects of inducible nitric oxide synthase inhibitor on reperfusion injury in the pig liver.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Transplantation

• Publication date

  1999-09-27

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00007890-199909270-00013PMID 10515381
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of endothelins and nitric oxide in hepatic reperfusion injury in the rat

  1998cited by this paper
• Increased nitric oxide production in the liver in the perioperative period of partial hepatectomy with Pringle's maneuver.

  1998cited by this paper
• Effects of inhibition of nitric oxide synthase by aminoguanidine in acute endotoxemia.

  1997cited by this paper
• Calcium transients and calcium homeostasis in adult mouse fast-twitch skeletal muscle fibers in culture.

  1997cited by this paper
• Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.

  1997cited by this paper
• Simultaneous Measurement of Nitrite and Nitrate Levels as Indices of Nitric Oxide Release in the Cerebellum of Conscious Rats

  1997cited by this paper
• Inhibition of nitric oxide synthesis in ischemia/reperfusion of the rat liver is followed by impairment of hepatic microvascular blood flow.

  1997cited by this paper
• Correlation between nitric oxide production and preservation injury of sinusoidal endothelial cells during cold ischemia.

  1997cited by this paper
• Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts.

  1997cited by this paper
• Role of nitric oxide in oxygen transport in rat liver sinusoids during endotoxemia

  1997cited by this paper
• Protective effect of L-arginine on liver ischemia-reperfusion injury.

  1997cited by this paper
• Oxidative Stress during Post-Hypoxic-Ischemic Reperfusion in the Newborn Lamb: The Effect of Nitric Oxide Synthesis Inhibition

  1997cited by this paper
• Basal nitric oxide expresses endogenous cardioprotection during reperfusion by inhibition of neutrophil-mediated damage after surgical revascularization.

  1997cited by this paper
• N omega-nitro-L-arginine attenuates early ischemic neuronal damage of prolonged focal cerebral ischemia and recirculation in rats.

  1997cited by this paper
• Role of nitric oxide in lung ischemia and reperfusion injury.

  1996cited by this paper
• Changes in plasma nitrite/nitrate level after orthotopic liver transplantation in pigs.

  1996cited by this paper
• Immunohistochemical localization of hepatic nitric oxide synthase in normal and transgenic sickle cell mice: the effect of hypoxia.

  1996cited by this paper
• Blood coagulation in the hepatic sinusoids as a contributing factor in liver injury following orthotopic liver transplantation in the rat.

  1996cited by this paper
• Nitric oxide decreases lung injury after intestinal ischemia.

  1996cited by this paper
• Lipopolysaccharide-induced hypotension and vascular hyporeactivity in the rat: tissue analysis of nitric oxide synthase mRNA and protein expression in the presence and absence of dexamethasone, NG-monomethyl-L-arginine or indomethacin.

  1995cited by this paper
• INHIBITION OF NITRIC OXIDE SYNTHESIS AGGRAVATES REPERFUSION INJURY AFTER HEPATIC ISCHEMIA AND ENDOTOXEMIA

  1995cited by this paper
• The delicate balance of nitric oxide and superoxide in liver pathology.

  1995cited by this paper
• Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion.

  1995cited by this paper
• Nitric oxide synthases: properties and catalytic mechanism.

  1995cited by this paper
• Role of endogenous nitric oxide in ischemia-reperfusion injury in rat liver.

  1995cited by this paper
• L-Arginine deficiency after liver transplantation as an effect of arginase efflux from the graft. Influence on nitric oxide metabolism.

  1994cited by this paper
• Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats.

  1994cited by this paper
• Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide.

  1994cited by this paper
• Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia.

  1994cited by this paper
• Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

  1994cited by this paper
• Role of EDRF in the regulation of regional blood flow and vascular resistance at rest and during exercise in conscious dogs.

  1994cited by this paper
• Nitric oxide synthases in mammals.

  1994cited by this paper
• Complement activation during liver transplantation.

  1993cited by this paper
• Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

  1993cited by this paper
• Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene.

  1993cited by this paper
• Role of platelets in hepatic allograft preservation injury in the rat

  1993cited by this paper
• Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

  1992cited by this paper
• Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia

  1992cited by this paper
• LEUKOCYTE ADHESION AND CELL DEATH FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

  1991cited by this paper
• Evaluation of the electroinjection method for introducing proteins into living cells.

  1991cited by this paper
• Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia

  1991cited by this paper
• Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver.

  1991cited by this paper
• Assessment of reperfusion injury by intravital fluorescence microscopy following liver transplantation in the rat.

  1990cited by this paper
• Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells

  1990cited by this paper
• Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

  1990cited by this paper
• Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat.

  1990cited by this paper
• Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

  1989cited by this paper
• Reperfusion injury to endothelial cells following cold ischemic storage of rat livers

  1989cited by this paper
• Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells

  1989cited by this paper
• Endotoxemia and human liver transplantation.

  1989cited by this paper
• Generation of nitric oxide by human neutrophils.

  1989cited by this paper
• Endogenous endotoxemia during orthotopic liver transplantation in dogs.

  1989cited by this paper
• Nitric oxide: a cytotoxic activated macrophage effector molecule.

  1988cited by this paper
• SINUSOIDAL LINING CELL DAMAGE: THE CRITICAL INJURY IN COLD PRESERVATION OF LIVER ALLOGRAFTS IN THE RAT

  1988cited by this paper
• Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

  1987cited by this paper
• The importance of O2-derived free radical injury to organ preservation and transplantation.

  1987cited by this paper
• Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.

  1987cited by this paper
• Effects of heparin and aminoguanidine on anaphylatoxin activity in the guinea-pig.

  1987cited by this paper
• Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

  1987cited by this paper
• Endothelium‐derived relaxing factor inhibits in vitro platelet aggregation

  1987cited by this paper
• Eicosonoid metabolism and beta-adrenergic mechanisms in coronary arterial smooth muscle: potential compartmentation of cAMP.

  1986cited by this paper
• Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

  1986cited by this paper
• Hemodynamic and biochemical monitoring during major liver resection with use of hepatic vascular exclusion.

  1984cited by this paper
• Cell surface changes and enzyme release during hypoxia and reoxygenation in the isolated, perfused rat liver

  1983cited by this paper
• Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids.

  1982cited by this paper
• Centrilobular injury following hypoxia in isolated, perfused rat liver.

  1981cited by this paper
• Method for measuring hepatic uptake of oxygen or other blood-borne substances in situ.

  1976cited by this paper
• Reticuloendothelial dysfunction and endotoxemia following protal vein occlusion.

  1974cited by this paper
• Effect of ligation of the hepatic artery or occlusion of the portal vein on the development of endotoxema.

  1974cited by this paper

• Atherosclerosis Deteriorates Liver Ischemia/Reperfusion Injury Via Interferon Regulatory Factor-1 Overexpression in a Murine Model.

  2024cites this paper
• Improving Liver Graft Function Using CD47 Blockade in the Setting of Normothermic Machine Perfusion

  2021cites this paper
• Tender Coconut Water Protects Mice From Ischemia-Reperfusion-Mediated Liver Injury and Secondary Lung Injury

  2021cites this paper
• Transient Expression of Reck Under Hepatic Ischemia/Reperfusion Conditions Is Associated with Mapk Signaling Pathways

  2020cites this paper
• iNOS/NO is required for IRF1 activation in response to liver ischemia-reperfusion in mice

  2020cites this paper
• Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury

  2020cites this paper
• Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality—the important role of hepatic microcirculation in donation after circulatory death

  2020cites this paper
• The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia–Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats

  2019cites this paper
• Effects of heme oxygenase-1-modified bone marrow mesenchymal stem cells on microcirculation and energy metabolism following liver transplantation

  2017cites this paper
• Melatonin Supplementation Ameliorates Energy Charge and Oxidative Stress Induced by Acute Exercise in Rat Heart Tissue.

  2017cites this paper
• V-PYRRO/NO downregulates mRNA expression levels of leukotriene C4 synthase during hepatic ischemia reperfusion injury in rats via inhibition of the nuclear factor-κB activation pathway.

  2016cites this paper
• Corosolic acid suppresses the expression of inflammatory marker genes in CCL4-induced-hepatotoxic rats.

  2016cites this paper
• Protective Effect of Nitric Oxide on Liver Circulation from Ischemia Reperfusion Injury

  2015cites this paper
• Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice.

  2015cites this paper
• UW solution improved with high anti-apoptotic activity by S-nitrosated human serum albumin.

  2013cites this paper
• Experimental data suggesting that inflammation mediated rat liver mitochondrial dysfunction results from secondary hypoxia rather than from direct effects of inflammatory mediators

  2013cites this paper
• Poly-S-Nitrosated Albumin as a Safe and Effective Multifunctional Antitumor Agent: Characterization, Biochemistry and Possible Future Therapeutic Applications

  2013cites this paper
• Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers.

  2012cites this paper
• Interplay of endothelial and inducible nitric oxide synthases modulates the vascular response to ischaemia–reperfusion in the rabbit lung

  2012cites this paper
• Impact of albumin on drug delivery--new applications on the horizon.

  2012cites this paper
• Matrix-leukocyte interactions in liver ischemia-reperfusion injury.

  2012cites this paper
• Nitric oxide in gingival crevicular fluid and nitric oxide synthase expression in the gingiva of patients with sickle cell disease.

  2011cites this paper
• Interaction of the nitric oxide signaling system with the Sphingomyelin cycle and Peroxidation on transmission of toxic signal of tumor necrosis factor-α in ischemia-reperfusion

  2011cites this paper
• Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.

  2011cites this paper
• Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl(4)-intoxicated mice.

  2011cites this paper
• Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion.

  2010cites this paper
• N-Acetylcysteine Improves the Viability of Human Hepatocytes Isolated from Severely Steatotic Donor Liver Tissue

  2010cites this paper
• Alterations in L-Arginine Metabolism After Lung Transplantation

  2010cites this paper
• Nitric Oxide, Oxidative Stress, Immune Response and Critical Care

  2010cites this paper
• The antioxidant role of oral administration of garlic oil on renal ischemia–reperfusion injury

  2010cites this paper
• Inhibition of Inducible Nitric Oxide Synthase Prevents Mitochondrial Damage and Improves Survival of Steatotic Partial Liver Grafts

  2010cites this paper
• Inhibition of inducible nitric oxide synthase prevents graft injury after transplantation of livers from rats after cardiac death

  2010cites this paper
• EINFLUSS VERSCHIEDENER ZELLPOPULATIONEN AUF DIE BILDUNG FREIER-RADIKAL-SPEZIES WÄHREND DER HYPERAKUTEN ABSTOSSUNG DER XENOPERFUNDIERTEN RATTENLEBER

  2009cites this paper
• Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury.

  2009cites this paper
• The Nutrigenetics of Hyperhomocysteinemia

  2009cites this paper
• Albumin as a nitric oxide-traffic protein: characterization, biochemistry and possible future therapeutic applications.

  2009cites this paper
• Expression of iNOS in early injury in a rat model of small-for-size liver transplantation.

  2009cites this paper
• Adverse Effects of a Clinically Relevant Dose of Hydroxyurea Used for the Treatment of Sickle Cell Disease on Male Fertility Endpoints

  2009cites this paper
• Cytoprotective Effects of a Cyclic RGD Peptide in Steatotic Liver Cold Ischemia and Reperfusion Injury

  2009cites this paper
• Danshen protects kidney grafts from ischemia/reperfusion injury after experimental transplantation

  2009cites this paper
• S-NITROSO-N-ACETILCISTEÍNA (SNAC) NA PRESERVAÇÃO DE FÍGADOS DE RATOS: ANÁLISE DO SEU EFEITO NO DANO PRECOCE DE ISQUEMIA/REPERFUSÃO

  2009cites this paper
• Prevention of Hepatic Ischemia/Reperfusion Injury by Prolonged Delivery of Nitric Oxide to the Circulating Blood in Mice

  2008cites this paper
• PROTECTIVE EFFECT OF FR183998, A Na+/H+ EXCHANGER INHIBITOR, AND ITS INHIBITION OF iNOS INDUCTION IN HEPATIC ISCHEMIA-REPERFUSION INJURY IN RATS

  2008cites this paper
• Oral beta-glucan protects kidney against ischemia/reperfusion injury in rats.

  2008cites this paper
• Sodium Nitroprusside Regulates mRNA Expressions of LTC4 Synthesis Enzymes in Hepatic Ischemia/Reperfusion Injury Rats via NF-κB Signaling Pathway

  2007cites this paper
• Decreased hepatic ischemia-reperfusion injury by manganese–porphyrin complexes

  2007influential citation
• The protective action of scutellarin against immunological liver injury induced by concanavalin A and its effect on pro‐inflammatory cytokines in mice

  2007cites this paper
• Oral β-Glucan Protects Kidney against Ischemia/Reperfusion Injury in Rats

  2007cites this paper
• New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis

  2007cites this paper
• Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro

  2007cites this paper
• Role of Hepatic Nitric Oxide Synthases in Rats with Thioacetamide‐induced Acute Liver Failure and Encephalopathy

  2007cites this paper
• Role of peroxynitrite on cytoskeleton alterations and apoptosis in renal ischemia-reperfusion.

  2007cites this paper
• Differential Mechanisms of Hepatic Vascular Dysregulation with Mild vs Moderate Ischemia /Reperfusion

  2007cites this paper
• Inhibition of Inducible Nitric Oxide Synthase Prevents Hepatic, but Not Pulmonary, Injury Following Ischemia-Reperfusion of Rat Liver

  2006cites this paper
• Effect of ischemic preconditioning in whole liver transplantation from deceased donors. A pilot study

  2006cites this paper
• Antioxidant therapy in liver ischemia‐reperfusion injury

  2006cites this paper
• The influence of propofol on P‐selectin expression and nitric oxide production in re‐oxygenated human umbilical vein endothelial cells

  2006cites this paper
• Cytoprotective function of tetrahydrobiopterin in rat liver ischemia/reperfusion injury.

  2006cites this paper
• Inhibition of inducible nitric oxide synthase promotes recovery of motor function in rats after sciatic nerve ischemia and reperfusion.

  2005cites this paper
• Remnant liver injury after hepatectomy with the pringle maneuver and its inhibition by an iNOS inhibitor (ONO-1714) in a pig model.

  2005cites this paper
• The contemporary role of antioxidant therapy in attenuating liver ischemia‐reperfusion injury: A review

  2005cites this paper
• The Effect of Normothermic Recirculation is Mediated by Ischemic Preconditioning in NHBD Liver Transplantation

  2005cites this paper
• A Study of the Metabolites of Ischemia-Reperfusion Injury and Selected Amino Acids in the Liver Using Microdialysis during Transplantation

  2005cites this paper
• NO Donor Ameliorates Ischemia–Reperfusion Injury of the Rat Liver With iNOS Attenuation

  2005cites this paper
• Endothelial nitric oxide synthase protects the post-ischemic liver: potential interactions with superoxide.

  2005cites this paper
• Effects of Inducible NOS Inhibition on Motor Function Recovery After Sciatic Nerve Ischemia and Reperfusion in Rats

  2005cites this paper
• Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins.

  2004cites this paper
• Nitric oxide involvement in reperfusion injury of denervated muscle.

  2004cites this paper
• Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide.

  2004cites this paper
• Ischemic preconditioning affects interleukin release in fatty livers of rats undergoing ischemia/reperfusion

  2004cites this paper
• Oxidant-mediated impairment of nitric oxide signaling in sickle cell disease--mechanisms and consequences.

  2004cites this paper
• Protection against concanavalin A-induced hepatocyte apoptosis by molsidomine is time-dependent.

  2004cites this paper
• Melatonin ameliorates renal ischemia/reperfusion injury.

  2004cites this paper
• Differential nitric oxide synthase expression during hepatic ischemia-reperfusion.

  2003cites this paper
• Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization.

  2003cites this paper
• Nitric oxide in liver transplantation: Pathobiology and clinical implications

  2003cites this paper
• Inflammatory mediator production in swine following endotoxin challenge with or without co-administration of dexamethasone.

  2003cites this paper
• Role of nitric oxide in liver injury.

  2003cites this paper
• Ischemia and hepatic reperfusion: Is it possible to reduce hepatic alterations?

  2003cites this paper
• Nitric Oxide-dependent Generation of Reactive Species in Sickle Cell Disease

  2003cites this paper
• Ischemia Reperfusion Injury in a Neonatal Rat Renal Transplantation Model

  2003cites this paper
• Fibronectin-α4β1 Integrin-Mediated Blockade Protects Genetically Fat Zucker Rat Livers from Ischemia/Reperfusion Injury

  2003cites this paper
• Role of inducible nitric oxide synthase in pig liver transplantation.

  2003cites this paper
• Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714

  2003cites this paper
• Fibronectin-alpha 4 beta 1 integrin-mediated blockade protects genetically fat Zucker rat livers from ischemia/reperfusion injury.

  2003cites this paper
• Kupffer Cells Protect Liver from Ischemia-Reperfusion Injury by an Inducible Nitric Oxide Synthase-Dependent Mechanism

  2002cites this paper
• In vivo regulation of inducible NO synthase in immune‐mediated liver injury in mice

  2002cites this paper
• Prediction of graft viability from non-heart-beating donor pigs using hepatic microdialysate hypoxanthine levels.

  2002cites this paper
• Immunologic role of nitric oxide in acute rejection of golden hamster to rat liver xenotransplantation.

  2002cites this paper
• Role of nitric oxide in liver ischemia and reperfusion injury

  2002cites this paper
• A novel inhibitor of inducible nitric oxide synthase (ono-1714) prevents critical warm ischemia-reperfusion injury in the pig liver

  2002influential citation
• Nitric Oxide in Liver Diseases

  2002cites this paper
• Immune-modulatory actions of arginine in the critically ill

  2002cites this paper
• Tumor necrosis factor suppression and microcirculatory disturbance amelioration in ischemia/reperfusion injury of rat liver after ischemic preconditioning †

  2002cites this paper
• Nitric oxide in liver diseases: friend, foe, or just passerby?

  2002cites this paper
• Enhanced post-ischemic liver injury in iNOS-deficient mice: a cautionary note.

  2001cites this paper
• Modulation of the inflammatory response in the cardiomyocyte and macrophage.

  2001cites this paper
• Papel del óxido nítrico durante la recirculación normotérmica en el trasplante hepático experimental en cerdos con donantes a corazón parado.

  2001cites this paper
• The effect of aprotinin on ischemia-reperfusion injury in the rabbit kidney.

  2001cites this paper
• Cardiocirculatory Management in Acute Lung Injury and ARDS

  2001cites this paper