Topical formulations and wound healing applications of chitosan.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Advanced Drug Delivery Reviews

• Publication date

  2001-11-05

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1016/S0169-409X(01)00189-2PMID 11718934
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evaluation effects of chitosan for the extracellular matrix production by fibroblasts and the growth factors production by macrophages.

  2001cited by this paper
• Chitosan accelerates the production of osteopontin from polymorphonuclear leukocytes.

  2001cited by this paper
• Influence of physico-chemical properties of chitin and chitosan on complement activation

  2000cited by this paper
• Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs.

  1999cited by this paper
• Effects of chitin and its derivatives on the proliferation and cytokine production of fibroblasts in vitro.

  1997cited by this paper
• Osteopontin is strongly expressed by histiocytes in granulomas of diverse etiology.

  1997cited by this paper
• Influence of chain length of N-acetyl-d-glucosamine and d-glucosamine residues on direct and complement-mediated chemotactic activities for canine polymorphonuclear cells

  1997cited by this paper
• Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

  1996cited by this paper
• Chitosan-inducing hemorrhagic pneumonia in dogs

  1996cited by this paper
• The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro.

  1995cited by this paper
• WOUND HEALING: THE ROLE OF THE MACROPHAGE AND OTHER IMMUNE CELLS

  1995cited by this paper
• The production of cytokines by polymorphonuclear neutrophils.

  1995cited by this paper
• Interleukin‐12 production by human polymorphonuclear leukocytes

  1995cited by this paper
• Chitosan-mediated stimulation of macrophage function.

  1994cited by this paper
• Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain.

  1994cited by this paper
• Migration of canine neutrophils to chitin and chitosan.

  1994cited by this paper
• Chitin and chitosan induce migration of bovine polymorphonuclear cells.

  1994cited by this paper
• Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption.

  1993cited by this paper
• Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene.

  1993cited by this paper
• Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response.

  1992cited by this paper
• Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts.

  1991cited by this paper
• Processing and Utilization of Chitin and Chitosan

  1990cited by this paper
• Cell attachment activity of the 44 kilodalton bone phosphoprotein is not restricted to bone cells.

  1989cited by this paper
• Effect of enhanced macrophage function on early wound healing.

  1988cited by this paper
• Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

  1986cited by this paper
• Stimulation of cytokine production in mice using deacetylated chitin.

  1986cited by this paper
• Characterization of the mannose/fucose receptor on human mononuclear phagocytes.

  1982cited by this paper
• A macrophage receptor for (mannose/glucosamine)-glycoproteins of potential importance in phagocytic activity.

  1980cited by this paper
• The role of extra-hepatic tissues in the receptor-mediated plasma clearance of glycoproteins terminated by mannose or N-acetylglucosamine.

  1980cited by this paper
• Promotion of wound repair in mice by application of glucan.

  1980cited by this paper
• The discovery of a potent pure chemical wound-healing accelerator.

  1970cited by this paper
• The acceleration of wound healing with cartilage. I.

  1957cited by this paper

• Comparative Analysis of Chitosan from Diverse Indian Fishery Wastes: Characterization and in Vitro Physicochemical and Biological Assessment for Pharmaceutical Uses

  2026cites this paper
• Engineering chitosan-functionalized liposomes for targeted drug delivery and biomedical applications.

  2026cites this paper
• Chitosan/hazelnut shell powder composites as innovative dressing in the treatment of wounds

  2026cites this paper
• Development of Antimicrobial Wound Healing Hydrogels Based on the Microbial Polysaccharide Pullulan

  2026cites this paper
• Influence of alkali treatment and ultrasonication on the bioactivities and rheological properties of sulfated polysaccharides.

  2025cites this paper
• Fabrication and characterization of metoprolol succinate loaded chitosan- guar gum based bio scaffolds for infected wound healing and tissue regeneration: In vitro and in vivo assessment.

  2025cites this paper
• Exploring the Potential of Chitosan–Phytochemical Composites in Preventing the Contamination of Antibiotic-Resistant Bacteria on Food Surfaces: A Review

  2025cites this paper
• Comparative evaluation of chitligsan nanosuspension gel and spray for enhancing full-thickness wound healing in a rat model

  2025cites this paper
• Treatment of Staphylococcus aureus-infected diabetic wounds by melatonin loaded nanocarriers

  2025cites this paper
• Natural polysaccharide-based hydrogels for hemostasis and wound healing: A review

  2025cites this paper
• Extraction, characterization and wound healing property of chitosan extracted from Penaeus indicus shells on mouse fibroblast (L929) cell line

  2025cites this paper
• Quaternized chitosan derivatives inhibit growth and affect biofilm formation of Staphylococcus aureus

  2025cites this paper
• Advances in Nanohybrid Hydrogels for Wound Healing: From Functional Mechanisms to Translational Prospects

  2025cites this paper
• Biocompatible nanostructured chitosan scaffolds for enhanced diabetic wound healing: Innovations and strategies

  2025cites this paper
• QbD Optimized Nanoemulsion Based Topical Formulation of Jatyadi Taila: Unveiling its In Vitro and In Vivo Efficacy for Enhanced Wound Healing

  2025cites this paper
• STRUCTURAL EVALUATION OF CHITOSAN-BIOACTIVE GLASS COATING ON WE43 MAGNESIUM ALLOY: A PRELIMINARY IN VITRO STUDY

  2025cites this paper
• Low-level laser and chitosan nanoparticles therapy speeds up the process of skin wound healing in mice: histological, hematological, and proinflammatory cytokines assessment

  2025cites this paper
• Molybdoenzymes-emulating bio-heterojunction hydrogel with rapid disinfection and macrophage reprogramming for wound regeneration.

  2025cites this paper
• Platelet-rich fibrin and chitosan dressings for healing after third molar extractions

  2025cites this paper
• Pioglitazone repurposing via in-situ gelling system: An effective topical strategy for wound management

  2025cites this paper
• Innovative Applications of Hydrogels in Contemporary Medicine

  2025cites this paper
• Injectable Chitosan Hydrogel Particles as Nasal Packing Materials After Endoscopic Sinus Surgery for Treatment of Chronic Sinusitis

  2025cites this paper
• Bioactive compounds in edible insects: Aspects of cultivation, processing and nutrition.

  2025cites this paper
• Chitosan based smart injectable hydrogels for biomedical applications: A comprehensive review

  2025cites this paper
• Chitosan-grafted Graphene Materials for Drug Delivery in Wound Healing.

  2024cites this paper
• Preparation of polymer composites with electrostatic spinning promotes wound regeneration: A review

  2024cites this paper
• Hydrogel-based immunoregulation of macrophages for tissue repair and regeneration.

  2024cites this paper
• Chitosan-Based Nanoformulations: Preclinical Investigations, Theranostic Advancements, and Clinical Trial Prospects for Targeting Diverse Pathologies

  2024cites this paper
• Ionically assembled hemostatic powders with rapid self-gelation, strong acid resistance, and on-demand removability for upper gastrointestinal bleeding.

  2024cites this paper
• Natural polymer nanofiber dressings for effective management of chronic diabetic wounds: A comprehensive review.

  2024cites this paper
• Evaluation of NiO nanoparticles infused Lup@CS nanocomposites for the degradation of Acridine Orange and Rose Bengal dyes

  2024cites this paper
• Chitosan biopolymer and its composites: Processing, properties and applications- A comprehensive review

  2024cites this paper
• An in vitro evaluation of Hypericum perforatum Loaded-Chitosan Nanoparticle/Agarose Film as a Wound Dressing

  2024cites this paper
• Clinical evaluation of the efficiency and safety of the Tromboguard® hemostatic dressing for donor sites of split-thickness skin graft: A multicenter study

  2024cites this paper
• Evaluation of the restorative effect of ozone and chitosan–hyaluronic acid with and without mesenchymal stem cells on wound healing in rats

  2024cites this paper
• Fabrication of Mupirocin-Loaded PEGylated Chitosan Nanoparticulate Films for Enhanced Wound Healing

  2024cites this paper
• Titanium Surface Modification Techniques to Enhance Osteoblasts and Bone Formation for Dental Implants: A Narrative Review on Current Advances

  2024cites this paper
• A review of phytochemicals isolated from corn silk and their medicinal applications

  2024cites this paper
• Use of Biomaterials in 3D Printing as a Solution to Microbial Infections in Arthroplasty and Osseous Reconstruction

  2024cites this paper
• Phosphorylation of chitin and chitosan: A review on its significance and various synthesis routes

  2024cites this paper
• Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity

  2024cites this paper
• Enzymatically gellable chitosan inks with enhanced printability by chitosan nanofibers for 3D printing of wound dressings

  2024cites this paper
• Non-thermal plasma treated and MXene (Ti3C2Tx)/Chitosan/TiO2 nanocomposite coated cotton fabrics-Antibacterial and wound healing applications

  2024cites this paper
• Electrospun Antimicrobial Drug Delivery Systems and Hydrogels Used for Wound Dressings

  2024cites this paper
• Spectroscopic, Hartree–Fock and DFT study of the molecular structure and electronic properties of functionalized chitosan and chitosan-graphene oxide for electronic applications

  2024cites this paper
• Biodegradable Polymers in Veterinary Medicine—A Review

  2024cites this paper
• Development of self-healing hydrogels to support choroidal endothelial cell transplantation for the treatment of early age related macular degeneration.

  2024cites this paper
• A novel chitosan-peptide system for cartilage tissue engineering with adipose-derived stromal cells.

  2024cites this paper
• All-in-one hydrogel patches with sprayed bFGF-loaded GelMA microspheres for infected wound healing studies.

  2024cites this paper
• Recent Applications of Chitosan and Its Derivatives in Antibacterial, Anticancer, Wound Healing, and Tissue Engineering Fields

  2024cites this paper
• Evaluation of smart bi-functional dressing based on polysaccharide hydrogels and Brassica oleracea extract for wound healing and continuous monitoring.

  2024cites this paper
• Chitosan as Biomaterial for Wound healing: Mechanisms and Various applications

  2024cites this paper
• Biodegradable Chitosan Sutures Enhanced with N-Acetyl-D-Glucosamine: Comparative Study with Catgut Sutures

  2024cites this paper
• Biopolymer based nanoparticles and their therapeutic potential in wound healing - A review.

  2024cites this paper
• Microwave-assisted synthesis of crosslinked ureido chitosan for hemostatic applications.

  2024cites this paper
• Fabrication and Characterizations of Microwave‐Assisted Gelatin Cross‐Linked LBG/Guar Gum–Based Super Porous Hydrogels With Metformin Hydrochloride for Open Incision Wound Healing

  2024cites this paper
• Development of self-healing hydrogels to support choroidal endothelial cell transplantation for the treatment of early age related macular degeneration

  2024cites this paper
• Comparative Analysis of Antibacterial and Wound Healing Activities of Chitosan and Povidone-Iodine–Based Hydrogels

  2024cites this paper
• Recent Advances in Topical Hemostatic Materials.

  2024cites this paper
• Synthesis and Characterization of Multifunctional Chitosan–Silver Nanoparticles: An In-Vitro Approach for Biomedical Applications

  2024cites this paper
• Harnessing the power of carbohydrates: Chitosan and starch-based nanocomposites for sustainable developments

  2024cites this paper
• Bio-inspired aFGF modification functionalized piezoelectric chitosan films for promoting scald wound healing.

  2024cites this paper
• Dextran-block-poly(benzyl glutamate) block copolymers via aqueous polymerization-induced self-assembly.

  2024cites this paper
• Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

  2023cites this paper
• Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective

  2023cites this paper
• Chitosan-based electrospun nanofibers for diabetic foot ulcer management; recent advances.

  2023cites this paper
• Chitin and Chitosan as Polymers of the Future—Obtaining, Modification, Life Cycle Assessment and Main Directions of Application

  2023cites this paper
• Effect of Chitosan-Diosgenin Combination on Wound Healing

  2023cites this paper
• Chitosan and Pectin Hydrogels for Tissue Engineering and In Vitro Modeling

  2023cites this paper
• Comparison and evaluation of effect of Chitosan as edible coating to maintain thepostharvest quality and enhance shelf-life of Psidium guajavaand Fragariaananassa fruits.

  2023influential citation
• Autoclaving-Triggered Hydrogelation of Chitosan-Gluconic acid Conjugate Aqueous Solution for Wound Healing

  2023cites this paper
• Visualization of the relationship between macrophage and wound healing from the perspective of bibliometric analysis

  2023cites this paper
• Pharmaceutical applications of chitosan in skin regeneration: A review.

  2023cites this paper
• Applications Of Chitosan Based Bionanocomposites In Drug-Delivery And Anticancer Treatment-A Review

  2023cites this paper
• Quaternized chitosan/PVA/natural bioactive agent electrospun wound scaffolds: production, characterization, and investigation of release kinetics

  2023cites this paper
• Harnessing the benefits of utilizing the optimal pH in conjunction with a hydrogel for wound care

  2023cites this paper
• Chitosan Particles Complexed with CA5-HIF-1α Plasmids Increase Angiogenesis and Improve Wound Healing

  2023cites this paper
• Two-phase matrices for the controlled release of therapeutic proteins.

  2023cites this paper
• A multifunctional and self-adaptive double-layer hydrogel dressing based on chitosan for deep wound repair.

  2023cites this paper
• Preparation of chitosan‐embedded recombinant human epidermal growth factor nanoparticles as accelerating compounds for skin remodelling in chronic lesions

  2023cites this paper
• Synthesis, Characterization and Biological Properties of Type I Collagen–Chitosan Mixed Hydrogels: A Review

  2023cites this paper
• Resveratrol-loaded co-axial electrospun poly(ε-caprolactone)/chitosan/polyvinyl alcohol membranes for promotion of cells osteogenesis and bone regeneration.

  2023cites this paper
• Dressing Materials: A Comprehensive Review

  2023cites this paper
• Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review

  2023cites this paper
• Exploring polysaccharide-based bio-adhesive topical film as a potential platform for wound dressing application: A review.

  2023cites this paper
• Cationic Porphyrins as Antimicrobial and Antiviral Agents in Photodynamic Therapy

  2023cites this paper
• Antibacterial activity and sustained release properties of curcumin-loaded chitosan microspheres/nanofiber composites membranes for wound healing applications

  2023cites this paper
• Chitosan-Based Hydrogels for Infected Wound Treatment.

  2023cites this paper
• Evaluation of antibacterial properties of polyvinyl alcohol/chitosan/potassium permanganate electrospun nanofibers

  2023cites this paper
• In-vitro and in-vivo assessment of Polycaprolactone-Chitosan-Pectin imbibed nanofiber potentials as a wound healing biomaterial

  2023cites this paper
• Vanillin based crosslinked films of CMCh-PVA for wound healing application

  2023cites this paper
• Silymarin chitosan-modified penetration enhancer microvesicles as a promising wound healing tool

  2023cites this paper
• Tannic acid-loaded chitosan-RGD-alginate scaffolds for wound healing and skin regeneration

  2023cites this paper
• A Novel Phytotherapy Application: Preparation, Characterization, Antioxidant Activities and Determination of Anti-inflammatory Effects by In vivo HET-CAM Assay of Chitosan-based DDSs Containing Endemic Helichrysum pamphylicum P.H. Davis & Kupicha Methanolic Extract

  2023cites this paper
• Review on Additives in Hydrogels for 3D Bioprinting of Regenerative Medicine: From Mechanism to Methodology

  2023cites this paper
• Emerging Advances in Microfluidic Hydrogel Droplets for Tissue Engineering and STEM Cell Mechanobiology

  2023cites this paper
• Evaluation of Chitosan Nanoparticle Antimicrobial Effect on Isolated Listeria monocytogenes Bacteria from Pregnant Women and L. monocytogenes ATCC 7644

  2022cites this paper
• A Comprehensive Review of Natural Compounds for Wound Healing: Targeting Bioactivity Perspective

  2022cites this paper
• Physical and antibacterial properties of Chitosan-guar-peppermint gel for improving wound healing

  2022cites this paper
• Wounds healing activities of topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats through activation of growth factors and suppression of matrix metalloproteinase expressions

  2022cites this paper