AhR-agonist-induced transcriptional changes of genes involved in thyroid function in primary porcine thyrocytes.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Toxicological Sciences

• Publication date

  2006-02-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/TOXSCI/KFJ042PMID 16291828
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Altered thyroxin and retinoid metabolic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in aryl hydrocarbon receptor-null mice

  2005cited by this paper
• Histologic Changes in Thyroid Glands from Great Cormorant (Phalacrocorax carbo) in Tokyo Bay, Japan: Possible Association with Environmental Contaminants

  2004cited by this paper
• Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats

  2004cited by this paper
• Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats.

  2004cited by this paper
• Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  2003cited by this paper
• Thyroid functions of mouse cathepsins B, K, and L.

  2003cited by this paper
• Adenomatous Hyperplasia of the Thyroid Gland in Beluga Whales (Delphinapterus leucas) from the St. Lawrence Estuary and Hudson Bay, Quebec, Canada

  2003cited by this paper
• Dioxin exposure and porcine reproductive hormonal activity.

  2002cited by this paper
• The sodium iodide symporter: its pathophysiological and therapeutic implications

  2002cited by this paper
• Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium.

  2002cited by this paper
• Trafficking of lysosomal cathepsin B—green fluorescent protein to the surface of thyroid epithelial cells involves the endosomal/lysosomal compartment

  2002cited by this paper
• Endocrine dismodulation and cancer.

  2002cited by this paper
• Cysteine Proteinases Mediate Extracellular Prohormone Processing in the Thyroid

  2001cited by this paper
• A REVIEW OF CHEMICALLY-INDUCED ALTERATIONS IN THYROID AND VITAMIN A STATUS FROM FIELD STUDIES OF WILDLIFE AND FISH

  2000cited by this paper
• Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism.

  1999cited by this paper
• The Na+/I− Symporter (NIS): Recent Advances

  1998influential reference
• N-linked Glycosylation of the Thyroid Na+/I− Symporter (NIS)

  1998influential reference
• Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health

  1998cited by this paper
• Regulation and tissue distribution of the human sodium iodide symporter gene

  1998cited by this paper
• Mechanisms of Ligand-Induced Aryl Hydrocarbon Receptor-Mediated Biochemical and Toxic Responses

  1998cited by this paper
• Aryl hydrocarbon receptor-mediated signal transduction.

  1997cited by this paper
• Ah receptor signaling pathways.

  1996cited by this paper
• Evidence for extracellularly acting cathepsins mediating thyroid hormone liberation in thyroid epithelial cells.

  1996cited by this paper
• The combined action of two thyroidal proteases releases T4 from the dominant hormone-forming site of thyroglobulin.

  1996cited by this paper
• Alterations in thyroid function in female Sprague-Dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  1995influential reference
• Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment.

  1995cited by this paper
• Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated male C57BL/6J and DBA/2J mice.

  1995cited by this paper
• Molecular events in the differentiation of the thyroid gland

  1995cited by this paper
• Iodide transport in the thyroid gland.

  1993cited by this paper
• Cell‐cell interactions in the process of differentiation of thyroid epithelial cells into follicles: A study by microinjection and fluorescence microscopy on in vitro reconstituted thyroid follicles

  1990cited by this paper
• Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys.

  1988cited by this paper
• Pathways of endocytosis in thyroid follicle cells.

  1984cited by this paper
• Formation of thyroid hormones.

  1982cited by this paper
• Carcinogenesis Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS No. 1746-01-6) in Osborne-Mendel Rats and B6C3F1 Mice (Gavage Study).

  1982cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• The aryl hydrocarbon receptor: structure, signaling, physiology and pathology

  2026cites this paper
• Effect of Gossypol on Gene Expression in Swine Granulosa Cells

  2024cites this paper
• In vitro effects of PCBs and OH-PCBs on the basal and dexamethasone-modified thyroid hormone metabolism in chicken liver

  2023cites this paper
• In vitro effects of polychlorinated biphenyls and their hydroxylated metabolites on the synthesis and metabolism of iodothyronines in the chicken (Gallus domesticus) thyroid gland.

  2022cites this paper
• Transcriptome Changes in Porcine Granulosa Cells in Response to Gossypol Cytotoxicity

  2021cites this paper
• Prenatal dioxin exposure and thyroid hormone levels in the Seveso second generation study.

  2020cites this paper
• SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner

  2020cites this paper
• Polychlorinated biphenyl toxicity in the thyroid gland of wild ungulates: an in vitro model

  2020cites this paper
• 5: Animal nutrition and immunity in pigs and poultry

  2019cites this paper
• Serum Concentration of Thyroid Hormones Long-Term after Sulfur Mustard Exposure

  2019influential citation
• In Vitro Cocktail Effects of PCB-DL (PCB118) and Bulky PCB (PCB153) with BaP on Adipogenesis and on Expression of Genes Involved in the Establishment of a Pro-Inflammatory State

  2018cites this paper
• Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

  2018cites this paper
• Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food

  2018cites this paper
• Resveratrol has anti-thyroid effects both in vitro and in vivo.

  2017cites this paper
• 2,3',4,4',5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.

  2016cites this paper
• Ginkgo biloba, friend or foe of thyroid follicular cells of adult male albino rats: a histological study

  2015cites this paper
• Comparison of the in vitro effects of TCDD, PCB 126 and PCB 153 on thyroid-restricted gene expression and thyroid hormone secretion by the chicken thyroid gland.

  2015cites this paper
• Molecular Mechanisms of 2, 3′, 4, 4′, 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells

  2015cites this paper
• Molecular mechanisms of human thyrocyte dysfunction induced by low concentrations of polychlorinated biphenyl 118 through the Akt/FoxO3a/NIS pathway

  2015cites this paper
• Toxicological effects of clofibric acid and diclofenac on plasma thyroid hormones of an Indian major carp, Cirrhinus mrigala during short and long-term exposures.

  2014cites this paper
• Inhibition of cathepsin B activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin

  2014influential citation
• Disruptive Effects of Organohalogenated Contaminants on Thyroid Hormone Levels in Glaucous Gulls (Larus hyperboreus) breeding in Kongsfjorden, Svalbard

  2014influential citation
• Activators of PPAR, RXR, AR, and Steroidogenic Factor 1

  2014cites this paper
• Peri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheep

  2013cites this paper
• The expression of aryl hydrocarbon receptor in porcine ovarian cells.

  2013cites this paper
• Elucidating Causes of Diporeia Decline in the Great Lakes via Metabolomics: Physiological Responses after Exposure to Different Stressors

  2013cites this paper
• Role of aryl hydrocarbon receptor in cancer.

  2013cites this paper
• Serum from Methimazole-Treated Patients Induces Activation of Aryl Hydrocarbon Receptor, a Transcription Factor That Binds to Dioxin-Response Elements

  2012cites this paper
• The possible roles of environmental factors and the aryl hydrocarbon receptor in the prevalence of thyroid diseases in Vietnam era veterans

  2011cites this paper
• Organizational changes to thyroid regulation: Evidence for predictive adaptive responses in Alligator mississippiensis

  2011cites this paper
• Xenobiotic metabolizing cytochrome P450 in pig, a promising animal model.

  2011cites this paper
• Hypothyroidism Induced by Polychlorinated Biphenyls and Up-Regulation of Transthyretin

  2010cites this paper
• Toxicología de las dioxinas y su impacto en la salud humana

  2010cites this paper
• Polychlorinated biphenyls have inhibitory effect on testicular steroidogenesis by downregulation of P45017α and P450scc

  2010cites this paper
• The impacts of organochlorines and other persistent pollutants on thyroid and metabolic health.

  2010influential citation
• Evidence for thyroid endocrine disruption in wild fish in San Francisco Bay, California, USA. Relationships to contaminant exposures.

  2010cites this paper
• Dioxins, PCBs, and Iodine: Effects on Synthesis and Metabolism of the Iodine Containing Thyroid Hormones

  2009cites this paper
• The aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism.

  2009cites this paper
• Hormonal regulation of CYP1A expression

  2009cites this paper
• Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.

  2008cites this paper
• Differential signatures of protein glycosylation and phosphorylation in human Chang liver cells induced by TCDD treatment.

  2008cites this paper
• Possible Effects of Environmental Nitrates and Toxic Organochlorines on Human Thyroid in Highly Polluted Areas in Slovakia

  2008cites this paper
• Thyroid ultrasound volume, structure and function after long-term high exposure of large population to polychlorinated biphenyls, pesticides and dioxin.

  2007cites this paper
• Clofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs.

  2007cites this paper
• An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls.

  2007cites this paper
• Research paper effects of 13-HPODE on expression of genes involved in thyroid hormone synthesis, iodide uptake and formation of hydrogen peroxide in porcine thyrocytes.

  2006cites this paper
• Approaches for assessing the presence and impact of thyroid hormone disrupting chemicals in delphinid cetaceans

  2006cites this paper