TLR10 Is a Negative Regulator of Both MyD88-Dependent and -Independent TLR Signaling

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Immunology

• Publication date

  2016-03-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1502599PMID 27022193PMCID PMC4868647
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Toll-Like Receptor Signaling Pathways

  2014cited by this paper
• Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection

  2014cited by this paper
• Human TLR10 is an anti-inflammatory pattern-recognition receptor

  2014cited by this paper
• Assembly and localization of Toll-like receptor signalling complexes

  2014influential reference
• Vita-PAMPs: signatures of microbial viability.

  2013cited by this paper
• Identification of TLR10 as a Key Mediator of the Inflammatory Response to Listeria monocytogenes in Intestinal Epithelial Cells and Macrophages

  2013cited by this paper
• Dissecting negative regulation of Toll-like receptor signaling.

  2012cited by this paper
• Molecular evolution of vertebrate Toll-like receptors: evolutionary rate difference between their leucine-rich repeats and their TIR domains.

  2012cited by this paper
• Variation in the TLR10/TLR1/TLR6 Locus is the Major Genetic Determinant of Inter-Individual Difference in TLR1/2-Mediated Responses

  2012cited by this paper
• Molecular evolution of vertebrate Toll-like receptors : evolutionary rate difference between their leucine-rich repeats and their TIR domains

  2011cited by this paper
• Human TLRs 10 and 1 Share Common Mechanisms of Innate Immune Sensing but Not Signaling

  2010cited by this paper
• The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

  2010cited by this paper
• Helical assembly in the MyD88:IRAK4:IRAK2 complex in TLR/IL-1R signaling

  2010cited by this paper
• The Crystal Structure of the Human Toll-like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer*

  2008influential reference
• The evolution of vertebrate Toll-like receptors.

  2005cited by this paper
• Human TLR10 Is a Functional Receptor, Expressed by B Cells and Plasmacytoid Dendritic Cells, Which Activates Gene Transcription through MyD881

  2005cited by this paper
• ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance

  2004cited by this paper
• SIGIRR, a negative regulator of Toll-like receptor–interleukin 1 receptor signaling

  2003cited by this paper
• Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides1

  2002cited by this paper
• Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.

  2001cited by this paper

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  2026cites this paper
• Deciphering Sjögren's disease: New insights and perspectives extend from advanced omics approaches and immunology.

  2026cites this paper
• Extracellular vesicles from mesenchymal stromal cells primed with synthetic toll-like receptor 4 agonists treat hematopoietic acute radiation syndrome

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• Updates on Toll‐Like Receptor 10 Research

  2025cites this paper
• Nobiletin Reduces LPS-Induced Neuroinflammation through TLR4/MyD88/NF-κB and Oxidative Stress via Nrf2/HO-1 Signaling in Human Microglial HMC3 Cells

  2025cites this paper
• Toll-like receptors in B cells and obesity.

  2025cites this paper
• Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19

  2025cites this paper
• TLR10: An Intriguing Toll-Like Receptor with Many Unanswered Questions

  2024cites this paper
• Downregulation of transcription 1 hinders the replication of Dabie bandavirus by promoting the expression of TLR7, TLR8, and TLR9 signaling pathway.

  2024cites this paper
• TLR10 (CD290) Is a Regulator of Immune Responses in Human Plasmacytoid Dendritic Cells.

  2024cites this paper
• Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors

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• Analysis of TLR10 gene polymorphisms in patients with rheumatoid arthritis.

  2024cites this paper
• Toll-like receptors and integrins crosstalk

  2024cites this paper
• Toll-like receptor 4 in pancreatic damage and immune infiltration in acute pancreatitis

  2024cites this paper
• Toll-like receptor 10 is down-regulated in serum of patients with relapsing–remitting multiple sclerosis but not associated with Epstein-Barr virus

  2023cites this paper
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  2023cites this paper
• Incomplete Knockdown of MyD88 Inhibits LPS-Induced Lung Injury and Lung Fibrosis in a Mouse Model

  2023cites this paper
• Analysis and prediction of pathogen nucleic acid specificity for toll-like receptors in vertebrates.

  2023cites this paper
• Next-Generation Adjuvants: Applying Engineering Methods to Create and Evaluate Novel Immunological Responses

  2023cites this paper
• Masking of typical TLR4 and TLR5 ligands modulates inflammation and resolution by Helicobacter pylori.

  2023cites this paper
• Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration

  2023influential citation
• TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to circulating, non-infectious immature dengue virus particles

  2022cites this paper
• Differential Gene Expression Induced by Different TLR Agonists in A549 Lung Epithelial Cells Is Modulated by CRISPR Activation of TLR10

  2022cites this paper
• cGAS in nucleus: The link between immune response and DNA damage repair

  2022cites this paper
• Anti-inflammatory effects of 9-cis-retinoic acid on β-amyloid treated human microglial cells

  2022cites this paper
• Structural and functional implications of leucine-rich repeats in toll-like receptor1 subfamily

  2022cites this paper
• TLR10 genotypes affect long-term graft function in tacrolimus-treated solid organ transplant recipients.

  2022cites this paper
• Toll-like receptors and their role in neuropathic pain and migraine

  2022cites this paper
• Therapeutic Cancer Vaccines—Antigen Discovery and Adjuvant Delivery Platforms

  2022cites this paper
• Toll-like receptor 10 gene polymorphism and risk of multiple sclerosis among Iraqi patients

  2022cites this paper
• Toll-like receptor 10 expression in B cells is negatively correlated with the progression of primary Sjögren's disease.

  2022cites this paper
• Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

  2021cites this paper
• Research progress on Toll-like receptor signal transduction and its roles in antimicrobial immune responses

  2021cites this paper
• Transcriptional Profiling of Early and Late Phases of Bovine Tuberculosis

  2021cites this paper
• Expression of TLR10 in Peripheral B Cell Subsets of Patients with Primary Sjögren’s Syndrome

  2021cites this paper
• Expression of TLR10 in B cells Correlates With Primary Sjögren’s Syndrome Progression

  2021cites this paper
• Toll-Like Receptors in Stem/Progenitor Cells.

  2021cites this paper
• TLR10 and Its Role in Immunity.

  2021cites this paper
• Toll-Like Receptors in Adaptive Immunity.

  2021cites this paper
• Toll-like receptors and hepatitis C virus infection.

  2021cites this paper
• Contrasting effects of the Toll-like receptor 4 in determining ovarian follicle endowment and fertility in female adult mice.

  2021cites this paper
• Toll-Like Receptors: Expression and Roles in Otitis Media

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System

  2021cites this paper
• Interaction between non-coding RNAs and Toll-like receptors.

  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020influential citation
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  2020cites this paper
• Unexplored horizons of cDC1 in immunity and tolerance.

  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Necroptosis in the periodontal homeostasis: Signals emanating from dying cells.

  2018cites this paper
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  2018cites this paper
• Investigating TLR-4 signalling in response to protein ligands

  2018cites this paper
• Innate Immunity and Inflammation

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Effect of TLR10 (2322A/G, 720A/C, and 992T/A) polymorphisms on the pathogenesis of Crimean Congo hemorrhagic fever disease

  2018cites this paper
• Human dendritic cell subsets: an update

  2018cites this paper
• Intracellular Antiviral Immunity

  2018cites this paper
• Polymorphisms in Toll-Like Receptor 10 and Tuberculosis Susceptibility: Evidence from Three Independent Series

  2018cites this paper
• Toll-like Receptor Agonist Conjugation: A Chemical Perspective.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• TLR10 Is a B Cell Intrinsic Suppressor of Adaptive Immune Responses

  2017cites this paper
• Activation of the Innate Immune Receptors: Guardians of the Micro Galaxy : Activation and Functions of the Innate Immune Receptors.

  2017cites this paper
• Characterization of the in vivo immunomodulatory properties of CD5 and CD6

  2017cites this paper
• De l’importance des médiateurs du stress dans le contrôle de l’immunité

  2017influential citation
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  2017cites this paper