Abnormal subcortical deep-gray matter susceptibility-weighted imaging filtered phase measurements in patients with multiple sclerosis: A case-control study

No abstract is available for this paper.

• Publication year

  2012

• Venue

  NeuroImage

• Publication date

  2012-01-02

• Fields of study

  Medicine, Computer Science

• Identifiers
  DOI 10.1016/j.neuroimage.2011.07.045PMID 21820063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Brain iron deposits are associated with general cognitive ability and cognitive aging.

  2012cited by this paper
• Differential effects of age and history of hypertension on regional brain volumes and iron

  2011cited by this paper
• Deep grey matter T2 hypo-intensity in patients with paediatric multiple sclerosis

  2011cited by this paper
• Quantitative imaging of intrinsic magnetic tissue properties using MRI signal phase: An approach to in vivo brain iron metabolism?

  2011cited by this paper
• A Bayesian model of shape and appearance for subcortical brain segmentation

  2011cited by this paper
• Iron stores and cerebral veins in MS studied by susceptibility weighted imaging.

  2010influential reference
• Correlation of putative iron content as represented by changes in R2* and phase with age in deep gray matter of healthy adults

  2010influential reference
• Brain iron detected by SWI high pass filtered phase calibrated with synchrotron X‐ray fluorescence

  2010influential reference
• Susceptibility mapping as a means to visualize veins and quantify oxygen saturation

  2010influential reference
• Whole-brain susceptibility mapping at high field: A comparison of multiple- and single-orientation methods

  2010cited by this paper
• Multiple Sclerosis and the Accumulation of Iron in the Basal Ganglia: Quantitative Assessment of Brain Iron Using MRI T2 Relaxometry

  2010cited by this paper
• Chronic cerebrospinal venous insufficiency and iron deposition on susceptibility-weighted imaging in patients with multiple sclerosis: a pilot case-control study.

  2010cited by this paper
• Atrophy mainly affects the limbic system and the deep grey matter at the first stage of multiple sclerosis

  2010cited by this paper
• Quantitative MR imaging of brain iron: a postmortem validation study.

  2010cited by this paper
• Deep gray matter T2 hypointensity is present in patients with clinically isolated syndromes suggestive of multiple sclerosis

  2010cited by this paper
• Thalamic damage and long-term progression of disability in multiple sclerosis.

  2010cited by this paper
• T2 hypointensity in the deep gray matter of patients with benign multiple sclerosis

  2009cited by this paper
• Diminished visibility of cerebral venous vasculature in multiple sclerosis by susceptibility‐weighted imaging at 3.0 Tesla

  2009cited by this paper
• Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging

  2009influential reference
• Quantitative assessment of brain iron by R2* relaxometry in patients with clinically isolated syndrome and relapsing–remitting multiple sclerosis

  2009influential reference
• Removing background phase variations in susceptibility‐weighted imaging using a fast, forward‐field calculation

  2009cited by this paper
• Detecting lesions in multiple sclerosis at 4.7 tesla using phase susceptibility‐weighting and T2‐weighting

  2009cited by this paper
• Age-related iron deposition in the basal ganglia: quantitative analysis in healthy subjects.

  2009cited by this paper
• 3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis

  2009cited by this paper
• Magnetic resonance imaging characteristics of children and adults with paediatric-onset multiple sclerosis.

  2009influential reference
• Deep Gray Matter Involvement on Brain MRI Scans Is Associated with Clinical Progression in Multiple Sclerosis

  2009cited by this paper
• Development of a robust method for generating 7.0 T multichannel phase images of the brain with application to normal volunteers and patients with neurological diseases

  2008influential reference
• Age, gender, and hemispheric differences in iron deposition in the human brain: An in vivo MRI study

  2008cited by this paper
• Evidence of thalamic gray matter loss in pediatric multiple sclerosis

  2008cited by this paper
• Quantitative in vivo magnetic resonance imaging of multiple sclerosis at 7 Tesla with sensitivity to iron

  2008influential reference
• Quantitative MR susceptibility mapping using piece‐wise constant regularized inversion of the magnetic field

  2008cited by this paper
• Calculation of the Magnetic Susceptibility from Susceptibility Weighted Phase Images

  2008cited by this paper
• Susceptibility-Weighted Imaging: Technical Aspects and Clinical Applications, Part 1

  2008cited by this paper
• The involvement of mitochondria in the pathogenesis of multiple sclerosis.

  2007cited by this paper
• Establishing a baseline phase behavior in magnetic resonance imaging to determine normal vs. abnormal iron content in the brain

  2007influential reference
• T1‐ and T2‐Based MRI Measures of Diffuse Gray Matter and White Matter Damage in Patients with Multiple Sclerosis

  2007cited by this paper
• Iron in chronic brain disorders: Imaging and neurotherapeutic implications

  2007influential reference
• Brain Aging and Its Modifiers

  2007cited by this paper
• Quantitative Assessment of Iron Accumulation in the Deep Gray Matter of Multiple Sclerosis by Magnetic Field Correlation Imaging

  2007cited by this paper
• Thalamic atrophy and cognition in multiple sclerosis

  2007cited by this paper
• Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis

  2006cited by this paper
• Prediction of longitudinal brain atrophy in multiple sclerosis by gray matter magnetic resonance imaging T2 hypointensity.

  2005cited by this paper
• MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis.

  2005influential reference
• Application of a Fourier‐based method for rapid calculation of field inhomogeneity due to spatial variation of magnetic susceptibility

  2005cited by this paper
• The Role of Iron in the Pathogenesis of Experimental Allergic Encephalomyelitis and Multiple Sclerosis

  2004cited by this paper
• Susceptibility weighted imaging (SWI)

  2004cited by this paper
• Thalamic Involvement in Multiple Sclerosis: A Diffusion‐Weighted Magnetic Resonance Imaging Study

  2003cited by this paper
• T2 hypointensity in the deep gray matter of patients with multiple sclerosis: a quantitative magnetic resonance imaging study.

  2002influential reference
• Thalamic neurodegeneration in multiple sclerosis

  2002influential reference
• Effects of IV methylprednisolone on brain atrophy in relapsing-remitting MS

  2001cited by this paper
• Gray matter T2 hypointensity is related to plaques and atrophy in the brains of multiple sclerosis patients.

  2001influential reference
• Proinflammatory cytokines promote glial heme oxygenase‐1 expression and mitochondrial iron deposition: implications for multiple sclerosis

  2001cited by this paper
• A global optimisation method for robust affine registration of brain images

  2001cited by this paper
• MRI T2 shortening (‘black T2’) in multiple sclerosis: frequency, location, and clinical correlation

  2000cited by this paper
• Ferritin, transferrin and iron concentrations in the cerebrospinal fluid of multiple sclerosis patients.

  1999cited by this paper
• Signal intensity on MRI of basal ganglia in multiple sclerosis.

  1995cited by this paper
• Abnormalities in Iron Metabolism in Multiple Sclerosis

  1989cited by this paper
• Perivascular iron deposition and other vascular damage in multiple sclerosis.

  1988cited by this paper
• Iron deposits surrounding multiple sclerosis plaques.

  1982cited by this paper

• Association Between Intermittent Fasting and Susceptibility-Weighted MRI Phase Values in Deep Gray Matter of Patients With Multiple Sclerosis: An Observational Cohort Study.

  2026cites this paper
• Ultra-low-field MRI for imaging of severe multiple sclerosis: a case-controlled study

  2025cites this paper
• Deep medullary veins: a promising neuroimaging marker for neurodegeneration in multiple sclerosis

  2025cites this paper
• Evaluating the role of anti-EBV antibodies as biomarkers for the evolution of multiple sclerosis: A longitudinal study.

  2025cites this paper
• Neuroimaging phenotype characterization of early aggressive and late severe multiple sclerosis: a case-control study

  2025cites this paper
• Choroid plexus enlargement is associated with future periventricular neurodegeneration in multiple sclerosis.

  2024cites this paper
• Quantitative Susceptibility Mapping Values Quantification in Deep Gray Matter Structures for Relapsing‐Remitting Multiple Sclerosis: A Systematic Review and Meta‐Analysis

  2024cites this paper
• Atrophy-Independent and Dependent Iron and Myelin Changes in Deep Gray Matter of Multiple Sclerosis: A Longitudinal Study Using χ-Separation Imaging.

  2024cites this paper
• Thalamic atrophy and dysconnectivity are associated with cognitive impairment in a multi-center, clinical routine, real-word study of people with relapsing-remitting multiple sclerosis

  2024cites this paper
• Neuroimaging assessment of facility-bound severely-affected MS reveals the critical role of cortical gray matter pathology: results from the CASA–MS case-controlled study

  2024cites this paper
• Magnetic resonance imaging detection of deep gray matter iron deposition in multiple sclerosis: A systematic review.

  2023cites this paper
• Reliability of paramagnetic rim lesion classification on quantitative susceptibility mapping (QSM) in people with multiple sclerosis: Single-site experience and systematic review.

  2023cites this paper
• Paramagnetic rim lesions are associated with greater incidence of relapse and worse cognitive recovery following relapse

  2023cites this paper
• Changes in iron load in specific brain areas lead to neurodegenerative diseases of the central nervous system.

  2023cites this paper
• Patient-Reported Outcome Severity and Emotional Salience Network Disruption in Multiple Sclerosis

  2022cites this paper
• Thalamic atrophy, duration of illness, and years of education are the best predictors of cognitive impairment in multiple sclerosis

  2022cites this paper
• Ceruloplasmin‐deficient mice show changes in PTM profiles of proteins involved in messenger RNA processing and neuronal projections and synaptic processes

  2022cites this paper
• Association of Choroid Plexus Inflammation on MRI With Clinical Disability Progression Over 5 Years in Patients With Multiple Sclerosis

  2022cites this paper
• Functional alteration due to structural damage is network dependent: insight from multiple sclerosis.

  2022cites this paper
• Thalamic atrophy measured by artificial intelligence in a multicentre clinical routine real-world study is associated with disability progression

  2022cites this paper
• A Preliminary Study of Alterations in Iron Disposal and Neural Activity in Ischemic Stroke

  2022cites this paper
• Digital Simulation Assessments of the Sensitivity of Quantitative MRI for Detection of an Iron Oxide Nanoparticle Brain MRI Contrast Agent

  2021cites this paper
• Lack of association between C282Y and H63D polymorphisms in the hemochromatosis gene and risk of multiple sclerosis: A meta-analysis.

  2021cites this paper
• Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study

  2021cites this paper
• CSF neurofilament light chain predicts 10-year clinical and radiologic worsening in multiple sclerosis

  2021cites this paper
• Quantifying disease pathology and predicting disease progression in multiple sclerosis with only clinical routine T2-FLAIR MRI

  2021cites this paper
• Nucleus basalis of Meynert damage and cognition in patients with multiple sclerosis

  2021cites this paper
• Thalamic Injury and Cognition in Multiple Sclerosis

  2021cites this paper
• Automated segmentation of deep brain nuclei using convolutional neural networks and susceptibility weighted imaging

  2021cites this paper
• Functional network dynamics and decreased conscientiousness in multiple sclerosis

  2021cites this paper
• Functional Connectivity and Structural Disruption in the Default‐Mode Network Predicts Cognitive Rehabilitation Outcomes in Multiple Sclerosis

  2020cites this paper
• Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study

  2020cites this paper
• Longitudinal Study of Iron Deposition and Volume in the Precentral Gyrus in Patients with Relapse-Remitting Multiple Sclerosis

  2020cites this paper
• Leptomeningeal, dura mater and meningeal vessel wall enhancements in multiple sclerosis.

  2020cites this paper
• Relationships Among Circulating Levels of Hemostasis Inhibitors, Chemokines, Adhesion Molecules, and MRI Characteristics in Multiple Sclerosis

  2020cites this paper
• Deep Gray Matter

  2020cites this paper
• Modelling Brain Lesion Volume in Patches with CNN-based Poisson Regression

  2020cites this paper
• Late onset multiple sclerosis is associated with more severe ventricle expansion.

  2020cites this paper
• Diffusion tensor imaging of the normal-appearing deep gray matter in primary and secondary progressive multiple sclerosis

  2020cites this paper
• Quantifying cognition and fatigue to enhance the sensitivity of the EDSS during relapses

  2020cites this paper
• Diagnosis of depression in multiple sclerosis is predicted by frontal–parietal white matter tract disruption

  2020cites this paper
• Quantitative proteomic analysis of cerebrospinal fluid of women newly diagnosed with multiple sclerosis

  2020cites this paper
• Advanced MRI features in relapsing multiple sclerosis patients with and without CSF oligoclonal IgG bands

  2020cites this paper
• Higher EBV response is associated with more severe gray matter and lesion pathology in relapsing multiple sclerosis patients: A case-controlled magnetization transfer ratio study

  2019cites this paper
• Venous and glymphatic drainage of the brain: Brief history of the International Society for Neurovascular Disease

  2019cites this paper
• Magnetic Resonance Imaging and Analysis in Multiple Sclerosis

  2019cites this paper
• Lower total cerebral arterial flow contributes to cognitive performance in multiple sclerosis patients

  2019cites this paper
• Serum neurofilament light chain levels associations with gray matter pathology: a 5‐year longitudinal study

  2019cites this paper
• Teriflunomide's effect on humoral response to Epstein-Barr virus and development of cortical gray matter pathology in multiple sclerosis.

  2019cites this paper
• Atrophied Brain T2 Lesion Volume at MRI Is Associated with Disability Progression and Conversion to Secondary Progressive Multiple Sclerosis.

  2019cites this paper
• Preserved network functional connectivity underlies cognitive reserve in multiple sclerosis

  2019cites this paper
• Targeting Iron Dyshomeostasis for Treatment of Neurodegenerative Disorders

  2019cites this paper
• Plasma levels of soluble NCAM in multiple sclerosis.

  2019cites this paper
• Altered hypothalamic metabolism in early multiple sclerosis - MR spectroscopy study.

  2019cites this paper
• Salient Central Lesion Volume: A Standardized Novel Fully Automated Proxy for Brain FLAIR Lesion Volume in Multiple Sclerosis

  2019cites this paper
• Response heterogeneity to home-based restorative cognitive rehabilitation in multiple sclerosis: An exploratory study.

  2019cites this paper
• Cumulative gadodiamide administration leads to brain gadolinium deposition in early MS

  2019cites this paper
• Spring 2019 ( + )-Naltrexone Effects on Anhedonia-Like Symptoms in a Low-Dose Model of Experimental Autoimmune Encephalomyelitis ( EAE )

  2019cites this paper
• An Investigation of the Relationship Between Structural Disruption and Functional Connectivity in Multiple Sclerosis and its Effect on Cognition

  2019cites this paper
• Lower self-report fatigue in multiple sclerosis is associated with localized white matter tract disruption between amygdala, temporal pole, insula, and other connected structures.

  2019cites this paper
• Effect of dimethyl fumarate on gray and white matter pathology in subjects with relapsing multiple sclerosis: a longitudinal study

  2018cites this paper
• Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality

  2018cites this paper
• Magnetic Resonance Imaging in Multiple Sclerosis.

  2018cites this paper
• White matter tract network disruption explains reduced conscientiousness in multiple sclerosis

  2018cites this paper
• [Anemia and dysregulation of iron metabolism in multiple sclerosis].

  2018cites this paper
• Deep gray matter volume loss drives disability worsening in multiple sclerosis

  2018cites this paper
• Walking disability measures in multiple sclerosis patients: Correlations with MRI-derived global and microstructural damage.

  2018cites this paper
• Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease

  2018cites this paper
• Quantitative Susceptibility Mapping of the Thalamus: Relationships with Thalamic Volume, Total Gray Matter Volume, and T2 Lesion Burden

  2018cites this paper
• Computational modelling of imaging markers to support the diagnosis and monitoring of multiple sclerosis

  2018cites this paper
• Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage

  2018cites this paper
• Effect of teriflunomide on gray and white matter brain pathology in multiple sclerosis using volumetric and diffusion-tensor imaging MRI measures.

  2018cites this paper
• Evaluation of Leptomeningeal Contrast Enhancement Using Pre-and Postcontrast Subtraction 3D-FLAIR Imaging in Multiple Sclerosis

  2018cites this paper
• Thalamic white matter in multiple sclerosis: A combined diffusion‐tensor imaging and quantitative susceptibility mapping study

  2018cites this paper
• MRI of cortical lesions and its use in studying their role in MS pathogenesis and disease course

  2018cites this paper
• Iron deposition quantification: Applications in the brain and liver

  2018cites this paper
• Increased CCL18 plasma levels are associated with neurodegenerative MRI outcomes in multiple sclerosis patients.

  2018cites this paper
• Body composition and the brain: investigating life history trade-offs in living humans

  2018cites this paper
• Thalamus volume change and cognitive impairment in early relapsing–remitting multiple sclerosis patients

  2018cites this paper
• Subcortical gray matter atrophy is associated with cognitive deficit in multiple sclerosis but not in systemic lupus erythematosus patients

  2018cites this paper
• Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain

  2017cites this paper
• White Matter Tract Injury is Associated with Deep Gray Matter Iron Deposition in Multiple Sclerosis

  2017cites this paper
• Chemical Elements and Oxidative Status in Neuroinflammation

  2017cites this paper
• Deep grey matter volume loss drives disability worsening in multiple sclerosis

  2017cites this paper
• Progressive iron accumulation across multiple sclerosis phenotypes revealed by sparse classification of deep gray matter

  2017cites this paper
• Methods for the computation of templates from quantitative magnetic susceptibility maps (QSM): Toward improved atlas‐ and voxel‐based analyses (VBA)

  2017cites this paper
• Thalamic Iron Differentiates Primary-Progressive and Relapsing-Remitting Multiple Sclerosis

  2017cites this paper
• Global and regional brain atrophy is associated with low or retrograde facial vein flow in multiple sclerosis

  2017cites this paper
• The clinical utility of QSM: disease diagnosis, medical management, and surgical planning

  2017cites this paper
• Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: A retrospective, pilot, observational longitudinal study

  2017cites this paper
• A Novel Semiautomated Pipeline to Measure Brain Atrophy and Lesion Burden in Multiple Sclerosis: A Long‐Term Comparative Study

  2017cites this paper
• An improved FSL-FIRST pipeline for subcortical gray matter segmentation to study abnormal brain anatomy using quantitative susceptibility mapping (QSM).

  2017cites this paper
• Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease

  2017cites this paper
• Computational method to measure vascular lesions in human brain digital images

  2017cites this paper
• Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals

  2017influential citation
• Serum iron concentration is associated with subcortical deep gray matter iron levels in multiple sclerosis patients

  2017cites this paper
• Transcranial sonography of subcortical structures in patients with multiple sclerosis

  2017cites this paper
• Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis

  2017cites this paper
• Efficacy and safety of a three-times-weekly dosing regimen of glatiramer acetate in relapsing–remitting multiple sclerosis patients: 3-year results of the Glatiramer Acetate Low-Frequency Administration open-label extension study

  2017cites this paper
• Cognition and disinhibition in multiple sclerosis : impact of MRI changes within thalamic tracts Submitted

  2016cites this paper