Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Carcinogenesis

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/CARCIN/3.11.1265PMID 6295653
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Electron microscopical demonstration of glucose-6-phosphatase in native cryostat sections fixed with glutaraldehyde through semipermeable membranes

  2004cited by this paper
• Semipermeable membranes for improving the histochemical demonstration of enzyme activities in tissue sections

  2004cited by this paper
• Metabolic zonation in thioacetamide-induced liver cirrhosis

  2004cited by this paper
• Kinetic models of glycogen metabolism in normal rat liver, Morris hepatoma 7787 and host liver.

  1980cited by this paper
• Glycogen metabolism in normal liver and Morris hepatoma 7787 in meal-fed rats.

  1980cited by this paper
• Hepatocellular glycogenosis and hepatocarcinogenesis.

  1980cited by this paper
• The first relevant cell stage in rat liver carcinogenesis. A quantitative approach.

  1980cited by this paper
• Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital.

  1978cited by this paper
• Different deviation patterns of carbohydrate-metabolizing enzymes in primary rat hepatomas induced by different chemical carcinogens.

  1978cited by this paper
• [Histochemical demonstration of glycogen phosphorylase (E.C. 2.4.11) through the use of semipermeable membranes (author's transl)].

  1978cited by this paper
• Enzymology of cancer cells (second of two parts).

  1977cited by this paper
• Enzymology of cancer cells (first of two parts).

  1977cited by this paper
• Sequential hepatic histologic and histochemical changes produced by diethylnitrosamine in the rhesus monkey.

  1976cited by this paper
• The control of glycogen metabolism in the liver.

  1976cited by this paper
• Quantitative cytochemical measurement of glyceraldehyde 3-phosphate dehydrogenase activity

  1976cited by this paper
• The microcirculatory acinar concept of normal and pathological hepatic structure.

  1976cited by this paper
• Sequential histological and histochemical study of the rat liver after single-dose aflatoxin B1 intoxication.

  1975cited by this paper
• Report of a workshop on classification of specific hepatocellular lesions in rats.

  1975cited by this paper
• [Glycogen and glucose-6-phosphatase during cancerization of rat liver cells by N-nitrosomorpholine (author's transl)].

  1974cited by this paper
• [Early histological and histochemical changes during experimental production of liver carcinoma by diethylnitrosamine].

  1972cited by this paper
• Aldehyde dehydrogenase activity in a rat hepatoma.

  1972cited by this paper
• Glucose-6-phosphatase activity in rat liver parenchyma during azo-dye carcinogenesis.

  1971cited by this paper
• Glucose‐6‐phosphatase activity in rat liver parenchyma during azo‐dye carctnogenesis

  1971cited by this paper
• Histochemical analysis of hyperplastic lesions and hepatomas of the liver of rats fed 2-fluorenylacetamide.

  1971cited by this paper
• [Histochemical investigations of carcinogenesis in rat liver after time-limited application of diethylnitrosamine].

  1969cited by this paper
• [Histochemical investigations of carcinogenesis in rat liver after continuous application of diethylnitrosamine].

  1969cited by this paper
• Carbohydrate metabolism in cancer cells and the molecular correlation concept

  1968cited by this paper
• Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism.

  1967cited by this paper
• PATTERNS OF GLYCOLYTIC ENZYMES IN RAT LIVER AND HEPATOMA.

  1965cited by this paper
• Glyceraldehyde 3-phosphate dehydrogenases: I. The protein chains in glyceraldehyde 3-phosphate dehydrogenase from pig muscle

  1965cited by this paper

• Understanding the Metabolic Cross Talk Between Cancer Cells and Cancer-Associated Fibroblasts

  2020cites this paper
• Cancer Cell Metabolism: A Potential Target for Cancer Therapy

  2020cites this paper
• Animal Models: A Useful Tool to Unveil Metabolic Changes in Hepatocellular Carcinoma

  2020cites this paper
• HBPD Table of Contents, Vol. 16, No. 6, 2017

  2017cites this paper
• Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma

  2017cites this paper
• Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay.

  2014cites this paper
• Glycogenotic hepatocellular carcinoma with glycogen-ground-glass hepatocytes: a heuristically highly relevant phenotype.

  2012cites this paper
• Liver and Pancreas

  2012cites this paper
• Specific alterations of carbohydrate metabolism are associated with hepatocarcinogenesis in mitochondrially impaired mice.

  2012cites this paper
• Upregulation of the Insulin Receptor and Type I Insulin-Like Growth Factor Receptor Are Early Events in Hepatocarcinogenesis

  2011influential citation
• Growth HMP-Shunt and Cholesterol Metabolism in Experimental Models Involving Normal and Preneoplastic Liver

  2011cites this paper
• Hepatocellular Glycogenosis and Hepatic Neoplasms

  2010cites this paper
• Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters.

  2009cites this paper
• Elevated activity of the oxidative and non‐oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver

  2008cites this paper
• Suppression of Early Stages of Neoplastic Transformation in a Two-Stage Chemical Hepatocarcinogenesis Model: Supplementation of Vanadium, a Dietary Micronutrient, Limits Cell Proliferation and Inhibits the Formations of 8-Hydroxy-2′-deoxyguanosines and DNA Strand-Breaks in the Liver of Sprague-Dawle

  2007cites this paper
• Effect of Solanum trilobatum on hepatic drug metabolising enzymes during diethylnitrosamine‐induced hepatocarcinogenesis promoted by Phenobarbital in rat

  2007cites this paper
• Glycine N‐methyltransferase−/− mice develop chronic hepatitis and glycogen storage disease in the liver

  2007cites this paper
• 9 – Liver and Pancreas

  2007cites this paper
• Hepatocarcinogenesis in the Rat Neoplastic Lesions during Nitrosamine-induced Development of Cytochrome P-450-altered Preneoplastic and Updated

  2006cites this paper
• Vanadium limits the expression of proliferating cell nuclear antigen and inhibits early DNA damage during diethylnitrosamine‐induced hepatocellular preneoplasia in rats

  2006cites this paper
• Use of two‐dimensional gel electrophoresis in predictive toxicology: Identification of potential early protein biomarkers in chemically induced hepatocarcinogenesis

  2005cites this paper
• Cocarcinogenic effects of islet hormones and N-nitrosomorpholine in hepatocarcinogenesis after intrahepatic transplantation of pancreatic islets in streptozotocin-diabetic rats.

  2005cites this paper
• Chronic liver injury by thioacetamide and promotion of hepatic carcinogenesis

  2004cites this paper
• Histochemical and microbiochemical demonstration of reduced pyruvate kinase activity in thioacetamide-induced neoplastic nodules of rat liver

  2004cites this paper
• In vivo and in vitro test for growth potential of liver cells from rats during early stage of hepatocarcinogenesis by 3′-methyl-4-dimethylaminoazobenzene

  2004cites this paper
• Sequential changes in growth kinetics and cellular phenotype during hepatocarcinogenesis

  2004cites this paper
• Decrease in glucokinase and glucose-6-phosphatase and increase in hexokinase in putative preneoplastic lesions of rat liver

  2004cites this paper
• Expression of glucose transporter 1 (Glut-1) in cell lines and clinical specimens from human prostate adenocarcinoma.

  2004cites this paper
• Non-persisting early foci of altered hepatocytes induced in rats by N-nitrosomorpholine

  2004cites this paper
• Specificity of cytochemical demonstration of adenylate cyclase in liver using adenylate-(β,γ-methylene) diphosphate as substrate

  2004cites this paper
• Over-expression of glucose transporter isoform GLUT1 and hexokinase I in rat renal oncocytic tubules and oncocytomas

  2004cites this paper
• Hepatotoxin N-nitrosomorpholine-induced carcinogenesis in rat liver: ex vivo exploration of preneoplastic and neoplastic hepatocytes.

  2003cites this paper
• Ultrasonographic evidence of phenotypic instability during hepatocarcinogenesis in N-nitrosomorpholine-treated rats.

  2002cites this paper
• Oxygen Insensitivity of the Histochemical Assay of Glucose-6-phosphate Dehydrogenase Activity for the Detection of (Pre)Neoplasm in Rat Liver

  2001cites this paper
• Are the Phenotypes of Preneoplastic Lesions of Significance for Cancer Prevention? 1. Liver.

  2001cites this paper
• Allosteric Activation of Acid α-Glucosidase by the Human Papillomavirus E7 Protein*

  2000cites this paper
• Hyperproliferative hepatocellular alterations after intraportal transplantation of thyroid follicles.

  2000cites this paper
• Digestive System 2

  2000cites this paper
• Hepatocellular alterations after intraportal transplantation of ovarian tissue in ovariectomized rats.

  2000cites this paper
• Allosteric activation of acid alpha-glucosidase by the human papillomavirus E7 protein.

  2000cites this paper
• Chemically induced preneoplastic lesions in rodents as indicators of carcinogenic activity.

  1999cites this paper
• Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine.

  1998cites this paper
• Low-number intrahepatic islet transplantation — a model of hormonal hepatocarcinogenesis

  1998cites this paper
• Short- and intermediate-term carcinogenicity testing--a review. Part 1: the prototypes mouse skin tumour assay and rat liver focus assay.

  1998cites this paper
• Early aberrations of energy metabolism in carcinogenesis

  1998cites this paper
• Differential expression of key enzymes of energy metabolism in preneoplastic and neoplastic rat liver lesions induced by N‐nitrosomorpholine and dehydroepiandrosterone

  1998cites this paper
• Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells

  1998cites this paper
• Short- and intermediate-term carcinogenicity testing--a review. Part 2: available experimental models.

  1998cites this paper
• Focal hepatic glycogenosis.

  1997cites this paper
• Early Bioenergetic Changes in Hepatocarcinogenesis: Preneoplastic Phenotypes Mimic Responses to Insulin And Thyroid Hormone

  1997cites this paper
• Foci of Altered Hepatocytes, Rat

  1997cites this paper
• Hexokinase expression in liver preneoplasia and neoplasia.

  1997cites this paper
• The in ovo carcinogenicity assay (IOCA): a review of an experimental approach for research on carcinogenesis and carcinogenicity testing.

  1997cites this paper
• Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver.

  1996cites this paper
• Altered liver acini induced in diabetic rats by portal vein islet isografts resemble preneoplastic hepatic foci in their enzymic pattern.

  1996cites this paper
• Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis.

  1995cites this paper
• Clofibrate-induced neoplastic development in the rat liver is associated with decreased connexin 32 expression but not with a co-ordinated shift in expression of marker enzymes.

  1995cites this paper
• Concepts in multistage carcinogenesis.

  1995cites this paper
• Rapid Induction of Preneoplastic Liver Foci in Embryonal Turkey Liver by Diethylnitrosamine

  1995cites this paper
• Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.

  1995cites this paper
• Cell proliferation and advancement of hepatocarcinogenesis in the rat are associated with a decrease in connexin 32 expression.

  1995cites this paper
• Spontaneous Hemangioendothelial Cell Hyperplasia of the Heart in B6C3F1 Female Mice

  1994cites this paper
• Enzymic Pattern of Preneoplastic and Neoplastic Lesions Induced in the Kidney of CBA Mice by 1,2-Dimethylhydrazine

  1994cites this paper
• Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.

  1994cites this paper
• Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation.

  1994cites this paper
• Overexpression of glucose-6-phosphate-dehydrogenase in rat hepatic preneoplasia and neoplasia.

  1994cites this paper
• Expression of L- and M2-pyruvate kinases in proliferating oval cells and cholangiocellular lesions developing in the livers of rats fed a methyl-deficient diet.

  1994cites this paper
• Preneoplastic foci of altered hepatocytes induced in rats by irradiation with alpha-particles of Thorotrast and neutrons.

  1994cites this paper
• Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine.

  1994cites this paper
• Sequential Functional and Morphological Alterations During Hepatocarcinogenesis Induced in Rats by Feeding of a Low Dose of 2-Acetylaminofluorene

  1994cites this paper
• Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine.

  1994cites this paper
• Reduction in the expression of glucose transporter protein GLUT 2 in preneoplastic and neoplastic hepatic lesions and reexpression of GLUT 1 in late stages of hepatocarcinogenesis.

  1993cites this paper
• Number of Simultaneously Expressed Enzyme Alterations Correlates with Progression of N‐Ethyl‐N‐hydroxyethylnitrosamine‐induced Hepatocarcinogenesis in Rats

  1993cites this paper
• Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats.

  1993cites this paper
• Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis.

  1993cites this paper
• Localization of glycogen synthase activity in liver of fasted normal and adrenalectomized rats after injection of dexamethasone

  1993cites this paper
• Expression of glucose transporter isoforms (GLUT1, GLUT2) and activities of hexokinase, pyruvate kinase, and malic enzyme in preneoplastic and neoplastic rat renal basophilic cell lesions

  1993cites this paper
• Modification of DENA-induced hepatocarcinogenesis by CCl4 cirrhosis. Comparison of the marker enzyme patterns.

  1992cites this paper
• Glycogen phosphorylase isoenzymes from hepatoma 3924A and from a non-tumorigenic liver cell line. Comparison with the liver and brain enzymes.

  1992cites this paper
• Effects of Modifying Agents on Conformity of Enzyme Phenotype and Proliferative Potential in Focal Preneoplastic and Neoplastic Liver Cell Lesions in Rats

  1992cites this paper
• Glycogen phosphorylase hyperactive foci of altered hepatocytes in aged rats

  1992cites this paper
• Preneoplastic Lesions as Early Indicators of Neoplastic Development

  1992cites this paper
• The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat.

  1992cites this paper
• Persistence of the cholangiocellular and hepatocellular lesions observed in rats fed a choline-deficient/DL-ethionine-supplemented diet.

  1992cites this paper
• Carbohydrate metabolism in human renal clear cell carcinomas.

  1992cites this paper
• Sequential changes in glycogen content, expression of glucose transporters and enzymic patterns during development of clear/acidophilic cell tumors in rat kidney.

  1992cites this paper
• Foci of altered hepatocytes induced in embryonal turkey liver.

  1992cites this paper
• Enhanced expression of low molecular weight keratins during progressive diethylnitrosamine-induced hepatocarcinogenesis in rats is associated with the presence of high levels of gamma-glutamyl transpeptidase and glycogen-deficient islands.

  1991cites this paper
• Cell Markers and Processes Related to Chemically Induced Carcinogenesis

  1991cites this paper
• Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.

  1991cites this paper
• Enzyme histochemistry and biochemical microanalysis of preneoplastic lesions.

  1991cites this paper
• Metabolic Aberrations and Metamorphosis during Chemical Carcinogenesis

  1991cites this paper
• Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet.

  1991cites this paper
• Glucose-6-phosphate Dehydrogenase Molecular forms in Different Experimental Models of Hepatic Cell Proliferation

  1991cites this paper
• Resolution of glycogen phosphorylase isoenzymes in precast Phastsystem polyacrylamide gels

  1991cites this paper
• Cytochemical, microbiochemical and molecular genetic analysis of chemical carcinogenesis.

  1991cites this paper
• Analysis of the Effects of Modifying Agents on Proliferation and Enzyme Phenotype in Focal Preneoplastic and Neoplastic Liver Lesions in Rats

  1991cites this paper
• Cytophotometric analysis of glycogen, protein and DNA of a glycogen-storing rat hepatoma (N13) cell line

  1991cites this paper
• Biochemical, morphological and flow cytometric evaluation of the effects of hexachlorobenzene on rat liver

  1990cites this paper
• Evaluation of the kinetics of the intracellular reduction of 2,6-dichlorophenolindophenol in normal and transformed hepatocytes measured by amperometric methods.

  1990cites this paper