Interaction of connexins with protein partners in the control of channel turnover and gating

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Biology of the Cell

• Publication date

  2002-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0248-4900(02)00015-1PMID 12566219
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cystic Fibrosis

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• Role of the Carboxyl Terminal of Connexin43 in Transjunctional Fast Voltage Gating

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• Unique and Redundant Connexin Contributions to Lens Development

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• c-Src Regulates the Interaction between Connexin-43 and ZO-1 in Cardiac Myocytes*

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• Connexin45 directly binds to ZO‐1 and localizes to the tight junction region in epithelial MDCK cells

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• Interaction of c-Src with Gap Junction Protein Connexin-43

  2001influential reference
• Emerging issues of connexin channels: biophysics fills the gap

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• Regulation of gap junctional communication by a pro-inflammatory cytokine in cystic fibrosis transmembrane conductance regulator-expressing but not cystic fibrosis airway cells.

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• The Carboxyl Terminal Domain Regulates the Unitary Conductance and Voltage Dependence of Connexin40 Gap Junction Channels

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• Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels.

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• Assembly of gap junction channels

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• An Internalization Signal in ClC-5, an Endosomal Cl−Channel Mutated in Dent's Disease*

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• Assembly of gap junction channels: mechanism, effects of calmodulin antagonists and identification of connexin oligomerization determinants.

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• PDZ domains and the organization of supramolecular complexes.

  2001cited by this paper
• Connexin45 Interacts with Zonula Occludens-1 and Connexin43 in Osteoblastic Cells*

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• Supramolecular dynamics of gap junctions.

  2001cited by this paper
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  2001cited by this paper
• Heterotypic docking of Cx43 and Cx45 connexons blocks fast voltage gating of Cx43.

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• Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein.

  2001cited by this paper
• v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication

  2001cited by this paper
• Connexin-43 Interactions with ZO-1 and α- and β-tubulin

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• Gap junction protein connexin-43 interacts directly with microtubules.

  2001influential reference
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• The origin of annular junctions: a mechanism of gap junction internalization.

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• Regulation of Cx43 Gap Junctions: The Gatekeeper and the Password

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• Regulation of gap junctions by phosphorylation of connexins.

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• Calmodulin Directly Gates Gap Junction Channels*

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• Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.

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• Coexpression of connexins 40 and 43 enhances the pH sensitivity of gap junctions: a model for synergistic interactions among connexins.

  2000influential reference
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function

  1999cited by this paper
• Junctional Communication Between Isolated Pairs of Canine Atrial Cells is Mediated by Homogeneous and Heterogeneous Gap Junction Channels

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• Functional and Morphological Correlates of Connexin50 Expressed in Xenopus laevis Oocytes

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• Chapter 13: Behavior of Chemical and Slow Voltage-Sensitive Gates of Connexin Channels: The “Cork” Gating Hypothesis

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  1999cited by this paper
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• Yes-Associated Protein 65 Localizes P62c-Yes to the Apical Compartment of Airway Epithelia by Association with Ebp50

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  1999influential reference
• Regulation of Connexin Channels by pH

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  1999cited by this paper
• Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels.

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• Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

  1999cited by this paper
• Molecular Bases for the Recognition of Tyrosine-based Sorting Signals

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• Trafficking pathways leading to the formation of gap junctions.

  1999influential reference
• Adaptors for clathrin-mediated traffic.

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• The ubiquitin system.

  1998cited by this paper
• A 17mer peptide interferes with acidification-induced uncoupling of connexin43.

  1998cited by this paper
• Molecular structure and assembly of the tight junction.

  1998cited by this paper
• The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein.

  1998cited by this paper
• Connexin32‐null mice develop demyelinating peripheral neuropathy

  1998cited by this paper
• Direct Association of the Gap Junction Protein Connexin-43 with ZO-1 in Cardiac Myocytes*

  1998cited by this paper
• The Pattern of Disulfide Linkages in the Extracellular Loop Regions of Connexin 32 Suggests a Model for the Docking Interface of Gap Junctions

  1998cited by this paper
• Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.

  1998cited by this paper
• Gap junctional communication modulates gene expression in osteoblastic cells.

  1998cited by this paper
• Isoform Composition of Connexin Channels Determines Selectivity among Second Messengers and Uncharged Molecules*

  1998cited by this paper
• The epidermal growth factor receptor tyrosine kinase phosphorylates connexin32

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• An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton*

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• Membrane Trafficking of the Cystic Fibrosis Gene Product, Cystic Fibrosis Transmembrane Conductance Regulator, Tagged with Green Fluorescent Protein in Madin-Darby Canine Kidney Cells*

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  1998cited by this paper
• Synthesis, assembly and structure of gap junction intercellular channels.

  1998influential reference
• Dynamics of connexins, E-cadherin and alpha-catenin on cell membranes during gap junction formation.

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  1997cited by this paper
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• Evidence for heteromeric gap junction channels formed from rat connexin43 and human connexin37.

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  1997influential reference
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• Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

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  1996cited by this paper
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