Dynamin recruitment and membrane scission at the neck of a clathrin-coated pit

Emanuele Cocucci,R. Gaudin,T. Kirchhausen

Published 2014 in Molecular Biology of the Cell

ABSTRACT

Dynamin2 dimers are the preferred assembly units recruited to coated pits. About 26 dynamins (one helical turn of a dynamin collar) are enough for release of most coated vesicles. A circumferential twist–propagating model is proposed that requires that one complete turn of the helix reach a state in which one or more pairs of GTPase domains interact.

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