Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Molecular Biology

• Publication date

  1999-05-07

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1006/JMBI.1999.2693PMID 10329150
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cyanovirin-N Binds to gp120 To Interfere with CD4-Dependent Human Immunodeficiency Virus Type 1 Virion Binding, Fusion, and Infectivity but Does Not Affect the CD4 Binding Site on gp120 or Soluble CD4-Induced Conformational Changes in gp120

  1999cited by this paper
• New methods of structure refinement for macromolecular structure determination by NMR.

  1998cited by this paper
• Crystallography & NMR system: A new software suite for macromolecular structure determination.

  1998cited by this paper
• Recombinant production of cyanovirin-N, a potent human immunodeficiency virus-inactivating protein derived from a cultured cyanobacterium.

  1998cited by this paper
• Mechanism and evolution of protein dimerization

  1998cited by this paper
• Solution structure of cyanovirin-N, a potent HIV-inactivating protein

  1998cited by this paper
• Determining the Magnitude of the Fully Asymmetric Diffusion Tensor from Heteronuclear Relaxation Data in the Absence of Structural Information

  1998cited by this paper
• [20] Processing of X-ray diffraction data collected in oscillation mode.

  1997cited by this paper
• Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

  1997cited by this paper
• Electron-density map interpretation.

  1997cited by this paper
• Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum.

  1997cited by this paper
• Construction and enhanced cytotoxicity of a [cyanovirin-N]-[Pseudomonas exotoxin] conjugate against human immunodeficiency virus-infected cells.

  1997cited by this paper
• Use of dipolar 1H–15N and 1H–13C couplings in the structure determination of magnetically oriented macromolecules in solution

  1997cited by this paper
• Analysis of sequence requirements for biological activity of cyanovirin-N, a potent HIV (human immunodeficiency virus)-inactivating protein.

  1997cited by this paper
• SHELXL: high-resolution refinement.

  1997cited by this paper
• Oligomer formation by 3D domain swapping: a model for protein assembly and misassembly.

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