gamma delta T cells in the human intestine express surface markers of activation and are preferentially located in the epithelium.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Cellular Immunology

• Publication date

  1990-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0008-8749(90)90053-TPMID 2113432
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phenotypic and functional analysis of gamma delta T cell receptor-positive murine dendritic epidermal clones.

  1989cited by this paper
• T cells against a bacterial heat shock protein recognize stressed macrophages.

  1989cited by this paper
• Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid

  1989cited by this paper
• Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells

  1989cited by this paper
• Lymphocytes bearing antigen-specific γδ T-cell receptors accumulate in human infectious disease lesions

  1989cited by this paper
• Antigens for γ/δ T cells

  1989cited by this paper
• Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions.

  1989cited by this paper
• The role of CD4 in T-cell activation: accessory molecule or co-receptor?

  1989cited by this paper
• Activation of gamma delta T cells in the primary immune response to Mycobacterium tuberculosis.

  1989cited by this paper
• Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system

  1989cited by this paper
• Tissue localization and CD8 accessory molecule expression of T gamma delta cells in humans.

  1989cited by this paper
• In vivo modulation of cytolytic activity and Thy-1 expression in TCR-gamma delta+ intraepithelial lymphocytes.

  1989cited by this paper
• Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.

  1989cited by this paper
• Immunology. Antigens for gamma/delta T cells.

  1989cited by this paper
• Phenotypic and functional analysis of γδ T cell receptor-positive murine dendritic epidermal clones

  1989cited by this paper
• Specificity and function of T cells bearing gamma delta receptors.

  1988cited by this paper
• Avian T cells expressing gamma delta receptors localize in the splenic sinusoids and the intestinal epithelium.

  1988cited by this paper
• Specificity and function of T cells bearing γδ receptors

  1988cited by this paper
• Intestinal intraepithelial lymphocytes are a distinct set of gamma delta T cells.

  1988cited by this paper
• Expression of the gamma-delta T-cell receptor on intestinal CD8+ intraepithelial lymphocytes.

  1988cited by this paper
• The expanding repertoire

  1988cited by this paper
• Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

  1988cited by this paper
• Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

  1988cited by this paper
• Appearance and phenotypic characterization of circulating Leu 19+ cells in cancer patients receiving recombinant interleukin 2.

  1988cited by this paper
• Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates.

  1988cited by this paper
• Stress proteins are immune targets in leprosy and tuberculosis.

  1988cited by this paper
• Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody

  1988cited by this paper
• Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation.

  1988cited by this paper
• A monoclonal antibody (HML‐1) defining a novel membrane molecule present on human intestinal lymphocytes

  1987cited by this paper
• Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines.

  1987cited by this paper
• Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody.

  1987cited by this paper
• Identification of a putative second T-cell receptor

  1986cited by this paper
• Immunohistological characterization of intraepithelial and lamina propria lymphocytes in control ileum and colon and in inflammatory bowel disease

  1986cited by this paper
• A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

  1986cited by this paper
• Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.

  1985cited by this paper
• Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

  1984cited by this paper

• Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs

  2026cites this paper
• Gamma delta T cells: Multifaceted mediators in pregnancy and the pathogenesis of miscarriage.

  2025cites this paper
• γδ T Cells: Game Changers in Immune Cell Therapy for Cancer

  2025cites this paper
• γδ T cells and head and neck squamous cell carcinoma.

  2025cites this paper
• A ligand-centered framework for γδ T cell activation in colorectal cancer revealed by single-cell and transformer-based perturbation

  2025cites this paper
• DEFA5-producing CD4+ T cells in the intestines of atopic dermatitis patients play an important role in the development of AD-associated intestinal inflammation

  2025cites this paper
• γδ T cells: origin and fate, subsets, diseases and immunotherapy

  2023cites this paper
• Tissue-Resident Immune Cells in Humans.

  2022cites this paper
• Mucosal vaccines — fortifying the frontiers

  2021cites this paper
• Mucosal vaccines — fortifying the frontiers

  2021cites this paper
• The Mucosal Immune System and Its Regulation by Autophagy

  2016cites this paper
• Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation

  2015cites this paper
• Role of Innate and Acquired Immune Mechanisms in Clinical Intestinal Transplant Rejection

  2015cites this paper
• Gardening Effect of Host Genetics on Human Intestinal Mucosal Microbiome and Its Link to Inflammatory Bowel Disease

  2014influential citation
• Postnatal Development of Lung T Lymphocytes in a Porcine Model

  2014cites this paper
• The Generation of Human

  2013cites this paper
• HIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota

  2013cites this paper
• Immunomodulation at epithelial sites by obesity and metabolic disease

  2012cites this paper
• The role of NLRs in induction and resolution of intestinal inflammation

  2012cites this paper
• The expression of CD25, CD11b, SWC1, SWC7, MHC-II, and family of CD45 molecules can be used to characterize different stages of γδ T lymphocytes in pigs.

  2012cites this paper
• Multiple independent lineages of HIV-1 persist in breast milk and plasma

  2011cites this paper
• Immunomodulation at epithelial sites by obesity and metabolic disease

  2011cites this paper
• HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites

  2010cites this paper
• HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites

  2010cites this paper
• γδ T lymphocytes: a new type of regulatory T cells suppressing murine 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis

  2008cites this paper
• Anthropological genetic analysis of human *disease from evolutionary, population, and clinical perspectives

  2008cites this paper
• Helicobacter infection alters the phenotype and inflammatory response of mouse intestinal muscle macrophages

  2008cites this paper
• EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA

  2007cites this paper
• Aggravation of intestinal inflammation by depletion/deficiency of γδ T cells in different types of IBD animal models

  2007cites this paper
• Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models.

  2007cites this paper
• Mucosal Immunopathogenesis of Feline Immunodeficiency Virus (FIV)

  2006cites this paper
• Reye syndrome

  2005cites this paper
• Influence of natural substances on mediators of intestinal inflammation "in vitro"

  2005cites this paper
• Reservoirs of HIV-1 in vivo: implications for antiretroviral therapy.

  2003cites this paper
• γδ T cells contribute to the systemic immunoglobulin E response and local B‐cell reactivity in allergic eosinophilic airway inflammation

  2003cites this paper
• Trafficking of Human Immunodeficiency Virus Type 1-Specific CD8+ T Cells to Gut-Associated Lymphoid Tissue during Chronic Infection

  2003cites this paper
• Delayed viral replication and CD4(+) T cell depletion in the rectosigmoid mucosa of macaques during primary rectal SIV infection.

  2003cites this paper
• Defence capabilities of human intestinal epithelial cells

  2003cites this paper
• Immunology of the Gastrointestinal Tract

  2003cites this paper
• HIV1 and the gut in the era of highly active antiretroviral therapy

  2002cites this paper
• Comparative Biology of γδ T Cells

  2002cites this paper
• Multiple accumulation of Vdelta2+ gammadelta T-cell clonotypes in intestinal mucosa from patients with Crohn's disease.

  2001cites this paper
• Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after gammadelta T cell depletion and no effect of alphabeta T cell depletion.

  2001cites this paper
• Molecular immunology of mucosal T cells

  2001cites this paper
• Sensitive and reproducible quantitation of mucosal HIV-1 RNA and DNA viral burden in patients with detectable and undetectable plasma viral HIV-1 RNA using endoscopic biopsies.

  2001influential citation
• Multiple Accumulation of Vδ2+ γδ T-Cell Clonotypes in Intestinal Mucosa from Patients with Crohn's Disease

  2001cites this paper
• Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after ãä T cell depletion and no eVect of áâ T cell depletion

  2001cites this paper
• Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after γδ T cell depletion and no effect of αβ T cell depletion

  2001cites this paper
• Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma.

  2001cites this paper
• Flow cytometric analysis of colonic and small intestinal mucosal lymphocytes obtained by endoscopic biopsy in the healthy dog.

  2000cites this paper
• Isolation of Cytomegalovirus-Specific Cytotoxic T-Lymphocytes from Gut-Associated Lymphoid Tissue (GALT) of HIV Type 1-Infected Subjects

  2000cites this paper
• Generation of human gammadelta T-cell repertoires.

  1999cites this paper
• Mukosales, gastrointestinales Immunsystem (GIS)

  1999cites this paper
• Mechanisms of immune cell-mediated tissue injury in inflammatory bowel disease (Review).

  1998cites this paper
• During Fetal Development T Cell Repertoires d g The Generation of Human

  1998cites this paper
• The Generation of Human γδ T Cell Repertoires During Fetal Development

  1998cites this paper
• Altered expression of alpha E beta 7 integrin on intra-epithelial and lamina propria lymphocytes in patients with Crohn's disease.

  1998cites this paper
• Phenotypes of T cells in the gut.

  1998cites this paper
• The generation of human gammadelta T cell repertoires during fetal development.

  1998cites this paper
• Distinct δ T cell receptor repertoires in monozygotic twins concordant for coeliac disease

  1997cites this paper
• γ T cells are decreased in the blood of children with Bordetella pertussis infection

  1997cites this paper
• Distinct delta T cell receptor repertoires in monozygotic twins concordant for coeliac disease.

  1997cites this paper
• The TCR-delta repertoire in human intestine undergoes characteristic changes during fetal to adult development.

  1997cites this paper
• 3 Special features of the intestinal lymphocytic system

  1996cites this paper
• Konzepte zur Immunpathogenese der chronischentzündlichen Darmerkrankungen

  1996cites this paper
• Lamina Propria Lymphocytes: A Unique Population of Mucosal Lymphocytes

  1996cites this paper
• Immunology of the Gut

  1996cites this paper
• Intraepitheliale Lymphozyten: Die erste Garde einer Immunabwehr?

  1996cites this paper
• Increase in the Expression of αEβ7, Characteristic of Intestinal Intraepethelial Lymphocytes, on T Cells in the Lung Epithelium of Patients with Interstitial Lung Diseases and in Synovial Fluid of Patients with Rheumatic Diseases

  1996cites this paper
• Special features of the intestinal lymphocytic system.

  1996cites this paper
• Increase in the expression of alpha E beta 7, characteristic of intestinal intraepithelial lymphocytes, on T cells in the lung epithelium of patients with interstitial lung diseases and in synovial fluid of patients with rheumatic diseases.

  1996cites this paper
• Regulation of immune responses of the intestinal mucosa.

  1996cites this paper
• Major pathways of mucosal immunity and inflammation: cell activation, cytokine production and the role of bacterial factors.

  1996cites this paper
• Quantitative und qualitative Aspekte der Lymphozytenmigration im Darmimmunsystem (Homing)

  1995cites this paper
• Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group.

  1995cites this paper
• The delta T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage.

  1995cites this paper
• Analysis of γδ region usage in normal and diseased human intestinal biopsies and peripheral blood by polymerase chain reaction (PCR) and flow cytometry

  1995cites this paper
• Lamina Propria T Cell Subsets in the Small and Large Intestine of Euthymic and Athymic Mice

  1995cites this paper
• Cholecystokinin-stimulated monocytes produce inflammatory cytokines and eicosanoids.

  1995cites this paper
• Cell Differentiation and Proliferation in the Gastrointestinal Tract with Respect to the Local Immune System a

  1994cites this paper
• 23 – Human Gastrointestinal Mucosal T Cells

  1994cites this paper
• Abnormalities in subset distribution, activation, and differentiation of T ceils isolated from large intestine biopsies in HIV infection

  1994cites this paper
• Abnormalities in subset distribution, activation, and differentiation of T cells isolated from large intestine biopsies in HIV infection. The Berlin Diarrhoea/Wasting Syndrome Study Group.

  1994cites this paper
• Morphologic evaluation of the pathogenesis of bacterial enteric infections.

  1994cites this paper
• Specific Activation of Human Peripheral Blood γ/δ+ T Lymphocytes by Sonicated Antigens of Mycobacterium tuberculosis: Role In Vitro in Killing Human Bladder Carcinoma Cell Lines

  1993cites this paper
• A comparative study of the characteristics of intraepithelial and lamina propria lymphocytes of the human nasal mucosa

  1993cites this paper
• Immunantworten im Darm unter normalen Bedingungen — Suppression, Helfermechanismen und die Rolle von T-Zellen

  1993cites this paper
• Organization of the murine T-cell receptor gamma locus.

  1993cites this paper
• T-cell receptor heterogeneity of gamma delta T-cell clones from human female reproductive tissues.

  1993cites this paper
• Enteric Immunologic Abnormalities in Human Immunodeficiency Virus Infection

  1992cites this paper
• Expression of T cell receptors alpha beta and gamma delta in the ileal mucosa of patients with Crohn's disease and with spondylarthropathy.

  1992cites this paper
• Phenotypical and Functional Characterization of Small Intestinal TcRγδ+ T Cells in Coeliac Disease

  1992cites this paper
• Phenotypical and functional characterization of small intestinal TcR gamma delta + T cells in coeliac disease.

  1992cites this paper
• T-cell receptor-gamma delta association with lymphocyte populations in sheep intestinal mucosa.

  1992cites this paper
• The Lamina Propria: a Dynamic, Complex Mucosal Compartment An Overview

  1992cites this paper
• Function and specificity of human gamma/delta-positive T cells.

  1992cites this paper
• T-cell receptors in ileal mucosal biopsies of patients with Crohn disease and spondylarthropathy.

  1992cites this paper
• Distribution of lymphocyte subsets and natural killer cells in the human body

  1992cites this paper
• A lectin-binding, protease-resistant mycobacterial ligand specifically activates V gamma 9+ human gamma delta T cells.

  1992cites this paper
• Expression of T cell receptors αβ and γδ in the ileal mucosa of patients with Crohn's disease and with spondylarthropathy

  1992cites this paper