Effect of timolol on mortality and reinfarction after acute myocardial infarction: prognostic importance of heart rate at rest.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  American Journal of Cardiology

• Publication date

  1986-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0002-9149(86)90234-1PMID 3524181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prediction of cardiovascular deaths and non-fatal reinfarctions after myocardial infarction.

  2009cited by this paper
• Haemodynamic and metabolic effects of timolol (Blocadren) on ischaemic myocardium.

  2009cited by this paper
• Effects of timolol on platelets in coronary sinus blood and on myocardial ischemia during pacing-induced angina.

  2009cited by this paper
• Practolol in acute myocardial infarction.

  2009cited by this paper
• The immediate antecedents of sudden death.

  2009cited by this paper
• Persantine-Aspirin Reinfarction Study. Part II. Secondary coronary prevention with persantine and aspirin.

  1986cited by this paper
• Comments — Beta-blockers: Heart rate reduction a mechanism of benefit

  1985cited by this paper
• A randomized trial of exercise training in patients with coronary heart disease.

  1984cited by this paper
• Hypokalaemia and ventricular fibrillation in acute myocardial infarction.

  1983cited by this paper
• The effect of pindolol on the two years mortality after complicated myocardial infarction.

  1983cited by this paper
• One year's treatment with propranolol after myocardial infarction: preliminary report of Norwegian multicentre trial.

  1982cited by this paper
• A long-term prevention study with oxprenolol in coronary heart disease.

  1982cited by this paper
• Controlled trial of sotalol for one year after myocardial infarction.

  1982cited by this paper
• Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial.

  1981cited by this paper
• Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction.

  1981cited by this paper
• Early intravenous atenolol treatment in suspected acute myocardial infarction. Preliminary report of a randomised trial.

  1980cited by this paper
• Heart rate as a prognostic factor for coronary heart disease and mortality: findings in three Chicago epidemiologic studies.

  1980cited by this paper
• EARLY INTRAVENOUS ATENOLOL TREATMENT IN SUSPECTED ACUTE MYOCARDIAL INFARCTION: Preliminary Report of a Randomised Trial

  1980cited by this paper
• Effect of alprenolol on mortality among patients with definite or suspected acute myocardial infarction. Preliminary results.

  1979cited by this paper
• EFFECT OF ALPRENOLOL ON MORTALITY AMONG PATIENTS WITH DEFINITE OR SUSPECTED ACUTE MYOCARDIAL INFARCTION

  1979cited by this paper
• Increased Diastolic Time: A Possible Important Factor in the Beneficial Effect of Propranolol in Patients with Coronary Artery Disease

  1979cited by this paper
• The Effects of Heart Rate, Myocardial Ischemia and Vagal Stimulation on the Threshold for Ventricular Fibrillation

  1977cited by this paper
• How seals avoid myocardial infarction during diving: do they show us a new approach to treatment of patients with ischaemic heart injury?

  1977cited by this paper
• Letter: Elemental diets.

  1975cited by this paper
• Improvement in prognosis of myocardial infarction by long-term beta-adrenoreceptor blockade using practolol. A multicentre international study.

  1975cited by this paper
• Control of ventricular arrhythmias during myocardial infarction by antilipolytic treatment using a nicotinic-acid analogue.

  1975cited by this paper
• Letter: Oral hypoglycaemics in diabetes mellitus.

  1975cited by this paper
• Use of Atropine in Patients with Acute Myocardial Infarction and Sinus Bradyeardia

  1975cited by this paper
• Reduction of sudden deaths after myocardial infarction by treatment with alprenolol. Preliminary results.

  1974cited by this paper
• Beneficial Effects of Vagal Stimulation and Bradycardia During Experimental Acute Myocardial Ischemia

  1974cited by this paper
• Deleterious effects of increased heart rate on infarct size in the conscious dog.

  1973cited by this paper
• Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions

  1971cited by this paper
• Consultants' views of general practitioners

  1967cited by this paper

• Analysis of Differentially Expressed Murine miRNAs in Acute Myocardial Infarction and Target Genes Related to Heart Rate

  2024cites this paper
• Admission Heart Rate and Mortality in Critically Ill Patients with Acute Aortic Dissection.

  2023cites this paper
• First post-discharge heart rate and long-term prognosis in patients with acute myocardial infarction.

  2022cites this paper
• Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes

  2021cites this paper
• The pulse; from adagio to prestissimo; the prognostic importance of heart rate increase and its associations with cardiovascular risk factors

  2020cites this paper
• Relation of Higher Resting Heart Rate to Risk of Cardiovascular Versus Noncardiovascular Death.

  2017cites this paper
• Heart rate as a marker of incidence and prognosis of cardiovascular diseases in different populations: Evidence from Linked Electronic Health Records using the CALIBER platform and the 4C clinical cohort

  2016cites this paper
• P Heart Failure hat Resting Heart Rate Should ne Aim For When Treating Patients ith Heart Failure With a Beta-Blocker ? xperiences From the Metoprolol Controlled Release / Extended Release andomized Intervention Trial in Chronic Heart Failure ( MERIT-HF )

  2016cites this paper
• Angina due to Obstructive Atherosclerotic Coronary Artery Disease: Diagnosis and Patient Risk Stratification

  2016cites this paper
• Heart Rate and Ischemic Stroke: The Reasons for Geographic and Racial Differences in Stroke (Regards) Study

  2015cites this paper
• Ivabradine: A Unique and Intriguing Medication for Treating Cardiovascular Disease.

  2015cites this paper
• Genetic Polymorphism rs6922269 in the MTHFD1L Gene Is Associated with Survival and Baseline Active Vitamin B12 Levels in Post-Acute Coronary Syndromes Patients

  2014cites this paper
• Resting, night-time, and 24 h heart rate as markers of cardiovascular risk in middle-aged and elderly men and women with no apparent heart disease.

  2013cites this paper
• Admission heart rate predicts mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction: an observational study.

  2013cites this paper
• Is there a role for β-blockade in septic shock?

  2013cites this paper
• Early β-blockade in acute myocardial infarction

  2013cites this paper
• Heart Rate Lowering by Specific and Selective If Current Inhibition with Ivabradine

  2012cites this paper
• Relationship between discharge heart rate and mortality in patients after acute myocardial infarction treated with primary percutaneous coronary intervention.

  2012cites this paper
• REVIEW ARTICLES Heart Rate - An Emerging Cardiovascular Risk Factor

  2012cites this paper
• Heart Rate – An Emerging Cardiovascular Risk Factor

  2012cites this paper
• ５．If 阻害薬

  2012cites this paper
• KCNE5 Polymorphism rs697829 is Associated with QT Interval and Survival in Acute Coronary Syndromes Patients

  2012cites this paper
• Effect of Carvedilol, Ivabradine or their combination on exercise capacity in patients with Heart Failure (the CARVIVA HF trial).

  2011cites this paper
• Resting Heart Rate Pattern During Follow-Up and Mortality in Hypertensive Patients

  2010cites this paper
• Antiarrhythmische Therapie mit β-Rezeptor-Antagonisten

  2010cites this paper
• The relationship between high resting heart rate and ventricular arrhythmogenesis in patients referred to ambulatory 24 h electrocardiographic recording.

  2010cites this paper
• What is the role of increased heart rate in stable coronary artery disease

  2010cites this paper
• Heart Rate Control in an Unselected Consecutive Population of Outpatients With Stable Coronary Artery Disease: Analysis of the CARDIf Study Cohort

  2010cites this paper
• Heart rate in ischemic heart disease. The innovation of ivabradine: More than pure heart rate reduction

  2010cites this paper
• Impact of ‘‘Off-Label’’ Use of Ivabradine on Exercise Capacity, Gas Exchange, Functional Class, Quality of Life, and Neurohormonal Modulation in Patients With Ischemic Chronic Heart Failure

  2010cites this paper
• Use of beta-blockers and effects on heart rate and blood pressure post-acute coronary syndromes: are we on target?

  2009cites this paper
• Is there a heart rate paradox – demystification of the myths?

  2009cites this paper
• Is Pretreatment with Beta-Blockers Beneficial in Patients with Acute Coronary Syndrome?

  2009cites this paper
• mittels Ivabradin auf die Endothelfunktion und Atherogenese

  2009cites this paper
• Heart rate management in coronary artery disease: the CLARIFY registry

  2009cites this paper
• Ivabradine: Beyond heart rate control

  2009cites this paper
• Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.

  2009cites this paper
• Heart rate, pacing, and outcome in the Dual Chamber and VVI Implantable Defibrillator (DAVID) trials.

  2009cites this paper
• Post-myocardial infarction beta-blocker therapy: the bradycardia conundrum. Rationale and design for the Pacemaker & beta-blocker therapy post-MI (PACE-MI) trial.

  2008cites this paper
• La fréquence cardiaque au repos : Un indicateur pronostique modifiable du risque et des issues cardiovasculaires ?

  2008cites this paper
• Resting heart rate: a modifiable prognostic indicator of cardiovascular risk and outcomes?

  2008influential citation
• Pathophysiological role of heart rate: from ischaemia to left ventricular dysfunction

  2008cites this paper
• University of Groningen Prescription of beta-blockers in patients with advanced heart failure and preserved left ventricular ejection fraction. Clinical implications and survival (letter) Dobre,

  2007cites this paper
• Prescription of beta‐blockers in patients with advanced heart failure and preserved left ventricular ejection fraction. Clinical implications and survival

  2007cites this paper
• Letters to the Editor

  2007cites this paper
• Resting heart rate in cardiovascular disease.

  2007cites this paper
• Coronary heart disease Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction : a meta-regression of randomized clinical trials

  2007influential citation
• The role of heart rate in the development of cardiovascular disease

  2007cites this paper
• Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction: a meta-regression of randomized clinical trials.

  2007cites this paper
• Prescription of beta-blockers in patients with advanced heart failure and preserved left ventricular ejection fraction. Clinical implications and survival.

  2007cites this paper
• The BEAUTIFUL Study: Randomized Trial of Ivabradine in Patients with Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction – Baseline Characteristics of the Study Population

  2007cites this paper
• The discovery of the selective If current inhibitor ivabradine: A new therapeutic approach to ischemic heart disease

  2006cites this paper
• Framingham Study Insights into Hypertensive of Cardiovascular Disease Risk

  2006cites this paper
• The discovery of the selective I(f) current inhibitor ivabradine. A new therapeutic approach to ischemic heart disease.

  2006cites this paper
• Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients.

  2006cites this paper
• Frequenza cardiaca e rischio cardiovascolare

  2006cites this paper
• What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF).

  2005cites this paper
• Chapter 23 – Coronary Atherosclerotic Sequelae of Hypertension

  2005cites this paper
• [Selection and pharmacological characterisation of Procoralan, a selective inhibitor of the pacemaker If current].

  2004cites this paper
• Sélection et caractérisation pharmacologique de Procoralan®, un inhibiteur sélectif du courant pacemaker If

  2004cites this paper
• Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease.

  2004cites this paper
• Does initial and delayed heart rate predict mortality in patients with acute coronary syndromes?

  2004cites this paper
• Anti-Ischemic Effects of Ivabradine, a Selective Heart Rate-Reducing Agent, in Exercise-Induced Myocardial Ischemia in Pigs

  2003cites this paper
• Heart Rate Versus Heart Rate Variability in Risk Prediction after Myocardial Infarction

  2003cites this paper
• The pathophysiology of perioperative myocardial infarction: facts and perspectives.

  2003cites this paper
• Procoralan, a new selective If current inhibitor

  2003cites this paper
• Ventricular Rate Control in Atrial Fibrillation: What is the Optimal Rate? The Concept of Controlling the Heart Rate Burden

  2003cites this paper
• Increased heart rate as a risk factor for cardiovascular disease

  2003cites this paper
• Cardiac Effects of Chronic Oral Beta‐Blockade:

  2002cites this paper
• Chronically Inhaled Salmeterol Improves Pulmonary Function in Heart Failure

  2002cites this paper
• [Analysis of the appropriate use of -blockers post-infarction].

  2001cites this paper
• Heart rate‐lowering and ‐regulating effects of once‐daily sustained‐release diltiazem

  2001cites this paper
• Morbidity and Mortality in Cardiovascular Disorders: Impact of Reduced Heart Rate

  2001cites this paper
• Análisis del uso adecuado de los bloqueadores beta en el postinfarto

  2001cites this paper
• β-Blocker: Aktivposten in der Behandlung der koronaren Herzkrankheit

  2001cites this paper
• Heart rate and mortality

  2000cites this paper
• Beta-blockers: recognising the assets in relation to coronary artery disease

  2000cites this paper
• Resting heart rate is a risk factor for cardiovascular and noncardiovascular mortality: the Chicago Heart Association Detection Project in Industry.

  1999cites this paper
• Beneficial effects of heart rate reduction on cardiac mechanics and energetics in patients with left ventricular dysfunction.

  1999cites this paper
• The safety and effectiveness of esmolol in the perioperative period in patients undergoing abdominal aortic surgery.

  1999cites this paper
• Heart rate as a risk factor in hypertensive individuals. The Italian TensioPulse Study.

  1999cites this paper
• The pharmacological basis and pathophysiological significance of the heart rate‐lowering property of diltiazem

  1999cites this paper
• Significance of reduction in heart rate in cardiovascular disease.

  1998cites this paper
• Herzfrequenzreduktion — ein wichtiger Mechanismus für eine günstige Beeinflussung der Prognose

  1997cites this paper
• Reappraisal of the importance of heart rate as a risk factor for cardiovascular morbidity and mortality.

  1997cites this paper
• Heart rate reduction in the treatment of chronic stable angina pectoris: experiences with a sinus node inhibitor.

  1996cites this paper
• Calcium channel blockers modify jejunal uptake of d-galactose in rabbits

  1996cites this paper
• Altered inotropic and lusitropic responses to heart rate in conscious dogs with tachycardia-induced heart failure.

  1996cites this paper
• The predictive value of admission heart rate on mortality in patients with acute myocardial infarction. SPRINT Study Group. Secondary Prevention Reinfarction Israeli Nifedipine Trial.

  1995cites this paper
• Framingham study insights into hypertensive risk of cardiovascular disease.

  1995cites this paper
• Differential and interactive effects of calcium channel blockers and cholesterol content of the diet on jejunal uptake of lipids in rabbits

  1994cites this paper
• The role of heart rate in myocardial ischemia and infarction: implications of myocardial perfusion-contraction matching.

  1993cites this paper
• Influence of heart rate on mortality among persons with hypertension: the Framingham Study.

  1993cites this paper
• [Which anti-ischemic treatment can be prescribed during and after the acute phase of myocardial infarction?].

  1992cites this paper
• Minimum heart rate and coronary atherosclerosis: independent relations to global severity and rate of progression of angiographic lesions in men with myocardial infarction at a young age.

  1992cites this paper
• Reduction of heart rate — Really a new concept in treating angina pectoris?

  1991cites this paper
• Can sudden death be avoided by timely revascularization of obstructed coronary arteries

  1991cites this paper
• Influence of heart rate on mortality after acute myocardial infarction.

  1990cites this paper
• Heart rate and beta-adrenergic mechanisms in acute myocardial infarction.

  1990cites this paper
• Heart Rate and β -Adrenergic Mechanisms in Acute Myocardial Infarction

  1990cites this paper