3'-UTR-dependent deadenylation by the yeast poly(A) nuclease.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Genes & Development

• Publication date

  1992-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.6.11.2088PMID 1358757
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transient translational silencing by reversible mRNA deadenylation.

  1992cited by this paper
• Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast.

  1992cited by this paper
• U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation

  1992cited by this paper
• Removal of a 3' non-coding sequence is an initial step in degradation of gro alpha mRNA and is regulated by interleukin-1.

  1992cited by this paper
• The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities

  1991cited by this paper
• Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

  1991cited by this paper
• An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA

  1991cited by this paper
• Regulation of mRNA turnover in eukaryotic cells.

  1991cited by this paper
• A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs

  1991cited by this paper
• A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation.

  1991cited by this paper
• The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

  1991cited by this paper
• An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro

  1991cited by this paper
• The role of poly(A) in the translation and stability of mRNA.

  1990cited by this paper
• Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae

  1990cited by this paper
• Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes.

  1990cited by this paper
• Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control.

  1990cited by this paper
• Poly(A), poly(A) binding protein and the regulation of mRNA stability.

  1989cited by this paper
• Synthesis of small RNAs using T7 RNA polymerase.

  1989cited by this paper
• Two phases in the addition of a poly(A) tail.

  1989cited by this paper
• The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation.

  1989cited by this paper
• Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases.

  1989cited by this paper
• cis-trans models for post-transcriptional gene regulation.

  1989cited by this paper
• Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation.

  1989cited by this paper
• Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells

  1989cited by this paper
• The a-factor pheromone of Saccharomyces cerevisiae is essential for mating

  1988cited by this paper
• Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

  1988cited by this paper
• A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability

  1987cited by this paper
• A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation.

  1986cited by this paper
• Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3')pp(5')A activated intermediate.

  1985cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• Processing of 9 E 3 mRNA and Regulation of Its Stability in Normal and Rous Sarcoma Virus-Transformed Cells

  year unknowncited by this paper

• Decoupled degradation and translation enables noise-modulation by poly(A)-tails

  2024influential citation
• A non-canonical Puf3p-binding sequence regulates CAT5/COQ7 mRNA under both fermentable and respiratory conditions in budding yeast

  2023cites this paper
• A structural biology view on the enzymes involved in eukaryotic mRNA turnover

  2023cites this paper
• The Dynamic Poly(A) Tail Acts as a Signal Hub in mRNA Metabolism

  2023cites this paper
• Poly(A) binding protein is required for mRNP remodeling to form P-bodies in mammalian cells

  2021cites this paper
• Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression

  2021cites this paper
• RNF219 interacts with CCR4–NOT in regulating stem cell differentiation

  2020cites this paper
• Poly(A)-Specific Ribonuclease PARN

  2020cites this paper
• Regulation of cytoplasmic RNA stability: Lessons from Drosophila

  2018cites this paper
• Do erythrocytic miRNA have a function

  2018cites this paper
• No Nonsense: The Protection of Wild-Type mRNAs From Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae

  2016cites this paper
• Mobilization of Dormant Cnot7 mRNA Promotes Deadenylation of Maternal Transcripts During Mouse Oocyte Maturation1

  2015cites this paper
• Title 1 Poly ( A ) binding protein is required for mRNP remodeling to form P-bodies in mammalian 2 cells 3 4 Running title 5 Poly ( A ) binding protein and P-body formation 6 7

  2015cites this paper
• In vitro analysis of RNA degradation catalyzed by deadenylase enzymes.

  2014cites this paper
• mRNA deadenylation by Pan2-Pan3.

  2014influential citation
• Deadenylation and its regulation in eukaryotic cells.

  2014cites this paper
• The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase

  2014cites this paper
• Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation

  2014influential citation
• Affinity purification of mRNA-protein complexes from Saccharomyces cerevisiae

  2014cites this paper
• PAN-orama: three convergent views of a eukaryotic deadenylase

  2014cites this paper
• mRNA Degradation and Decay

  2014cites this paper
• An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay

  2014cites this paper
• Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins.

  2013cites this paper
• RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes.

  2013cites this paper
• Activity and Function of Deadenylases.

  2012cites this paper
• Mechanisms of Vts1-Mediated Repression in S. cerevisiae

  2011cites this paper
• Mechanisms and control of mRNA turnover in the yeast saccharomyces cerevisiae.

  2011cites this paper
• mRNA Degradation Machinery in Plants

  2009influential citation
• The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

  2009cites this paper
• Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

  2009cites this paper
• Regulated deadenylation in vitro.

  2008cites this paper
• Regulation of phospholipid synthesis in Saccharomyces cerevisiae by mRNA stability

  2007cites this paper
• CUG-BP and 3'UTR sequences influence PARN-mediated deadenylation in mammalian cell extracts

  2007cites this paper
• Biochemical analysis of the mRNA scavenger decapping enzymes

  2007cites this paper
• Transcript-Specific Cytoplasmic Degradation of YRA1 Pre-mRNA Mediated by the Yeast EDC3 Protein: A Dissertation

  2007cites this paper
• Development of a mathematical model for the occupancy of mRNA with ribosomes in Saccharomyces cerevisiae

  2006cites this paper
• Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export.

  2005cites this paper
• ISOLATION AND CHARACTERIZATION OF THE FOUR ARABIDOPSIS THALIANA POLY(A) POLYMERASE GENES

  2005cites this paper
• Yeast mRNA Poly(A) Tail Length Control Can Be Reconstituted in Vitro in the Absence of Pab1p-dependent Poly(A) Nuclease Activity*

  2005cites this paper
• CHARACTERIZATION OF PLANT POLYADENYLATION TRANSACTING FACTORS-FACTORS THAT MODIFY POLY(A) POLYMERSE ACTIVITY

  2005influential citation
• Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes

  2004influential citation
• Structure and function of poly(A) binding proteins.

  2004cites this paper
• Positive and Negative Regulation of Poly(A) Nuclease

  2004influential citation
• Identification of a Human Cytoplasmic Poly(A) Nuclease Complex Stimulated by Poly(A)-binding Protein*

  2004cites this paper
• AtPARN is an essential poly(A) ribonuclease in Arabidopsis.

  2004cites this paper
• Identification of Factors Regulating Poly(A) Tail Synthesis and Maturation

  2004cites this paper
• Transcriptional elongation defects enhance upstream poly (A) site utilization and SPT5 affects mRNA degradation through its physical and functional interaction with CCR4 -NOT complex

  2003cites this paper
• mRNA degradation machines in eukaryotic cells.

  2002cites this paper
• Molecular Characterization of PAB 2 , a Member of the Multigene Family Coding for Poly ( A )-Binding Proteins in A ra bidopsis f halia n a ’

  2002cites this paper
• Evidence for multiple sequences and factors involved in c‐myc RNA stability during amphibian oogenesis

  2001cites this paper
• Purification of poly(A)-specific ribonuclease.

  2001cites this paper
• Poly(A)-Specific Ribonuclease (PARN)

  2001cites this paper
• A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.

  2001influential citation
• The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.

  2001cites this paper
• A 54-kDa Fragment of the Poly(A)-specific Ribonuclease Is an Oligomeric, Processive, and Cap-interacting Poly(A)-specific 3′ Exonuclease*

  2000cites this paper
• Control of mu opioid receptor expression by modification of cDNA 5'- and 3'-noncoding regions.

  2000cites this paper
• Cyclosporin A Promotes Translational Silencing of Autocrine Interleukin-3 via Ribosome-Associated Deadenylation

  1999cites this paper
• FUNCTIONS OF THE 3'-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES.

  1999cites this paper
• REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES

  1999cites this paper
• 6.13 – Turnover of mRNA in Eukaryotic Cells

  1999cites this paper
• Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis

  1999cites this paper
• Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited.

  1998cites this paper
• A tale of two termini: a functional interaction between the termini of an mRNA is a prerequisite for efficient translation initiation.

  1998cites this paper
• The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes

  1998cites this paper
• Pbp1p, a Factor Interacting withSaccharomyces cerevisiae Poly(A)-Binding Protein, Regulates Polyadenylation

  1998cites this paper
• Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

  1998cites this paper
• mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation.

  1998cites this paper
• Poly(A)-tail-promoted translation in yeast: implications for translational control.

  1998cites this paper
• Characterization of c-myc 3′ to 5′ mRNA Decay Activities in an in Vitro System*

  1998cites this paper
• Posttranscriptional Control of Gene Expression in Yeast

  1998cites this paper
• Molecular genetics of succinate:quinone oxidoreductase in eukaryotes.

  1998cites this paper
• Comparative analyses of the secondary structures of synthetic and intracellular yeast MFA2 mRNAs.

  1998cites this paper
• Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein.

  1997cites this paper
• The Role of 3′ Poly(A) Tail Metabolism in Tumor Necrosis Factor-α Regulation*

  1997cites this paper
• Cleavage properties of an estrogen-regulated polysomal ribonuclease involved in the destabilization of albumin mRNA.

  1997cites this paper
• Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease*

  1997cites this paper
• The wheat poly(A)-binding protein functionally complements pab1 in yeast.

  1997cites this paper
• The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains.

  1997cites this paper
• Function and characterization of poly(A)-specific 3' exoribonucleases.

  1997cites this paper
• Messenger RNA deadenylylation precedes decapping in mammalian cells.

  1997cites this paper
• Visualization of poly(A)-binding protein complex formation with poly(A) RNA using atomic force microscopy.

  1997cites this paper
• Kinetics of hairpin ribozyme cleavage in yeast.

  1997cites this paper
• Cell-free systems for analysis of cytoplasmic mRNA turnover.

  1997cites this paper
• Cytoplasmic fate of messenger RNA

  1997cites this paper
• Messenger RNA Ribonucleases and mRNA Turnover in Saccharomyces cerevisiae

  1997cites this paper
• RNA-Processing RNases in Mammalian Cells

  1997cites this paper
• A pollen-, ovule-, and early embryo-specific poly(A) binding protein from Arabidopsis complements essential functions in yeast.

  1996cites this paper
• PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae

  1996cites this paper
• Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells.

  1996cites this paper
• The sequence of 36·8 kb from the left arm of chromosome XIV reveals 24 complete open reading frames: 18 correspond to new genes, one of which encodes a protein similar to the human myotonic dystrophy kinase

  1996cites this paper
• Binding of a protein to an AU-rich domain of tumour necrosis factor alpha mRNA as a 35 kDa complex and its regulation in primary rat astrocytes.

  1996cites this paper
• Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC.

  1996cites this paper
• Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae

  1996influential citation
• Poly(A) metabolism in Xenopus laevis embryos: substrate-specific and default poly(A) nuclease activities are mediated by two distinct complexes.

  1996cites this paper
• The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism.

  1996cites this paper
• Changes in the Length of Poly(A) Tails and their Effects on mRNA Translation and Turnover

  1996cites this paper
• Overexpression of poly(A) binding protein prevents maturation‐specific deadenylation and translational inactivation in Xenopus oocytes.

  1996cites this paper
• Control of mRNA stability in higher plants

  1996influential citation
• The Yeast Pan2 Protein Is Required for Poly(A)-binding Protein-stimulated Poly(A)-nuclease Activity *

  1996cites this paper
• Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae.

  1996influential citation