A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Science

• Publication date

  2003-10-10

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1126/SCIENCE.1087447PMID 12934013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• IL-13受体α2降低血吸虫病肉芽肿的炎症反应并延长宿主存活时间[英]/Mentink-Kane MM,Cheever AW，Thompson RW，et al//Proc Natl Acad Sci U S A

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