Activation of a plasma membrane-associated neutral sphingomyelinase and concomitant ceramide accumulation during IgG-dependent phagocytosis in human polymorphonuclear leukocytes.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Blood

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/blood.v91.12.4761PMID 9616175
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ceramide inhibits IgG-dependent phagocytosis in human polymorphonuclear leukocytes.

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• Inhibition of the Neutral Magnesium-dependent Sphingomyelinase by Glutathione*

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• Ceramide: A stress signal and mediator of growth suppression and apoptosis

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• Compartmentalized Production of Ceramide at the Cell Surface (*)

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• Ceramide As a Modulator of Endocytosis (*)

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• Ceramide induces interleukin 6 gene expression in human fibroblasts

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• Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling.

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• Ceramide regulates oxidant release in adherent human neutrophils.

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• Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

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• Phospholipase D-mediated diradylglycerol formation coincides with H2O2 and lactoferrin release in adherent human neutrophils.

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• Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

  1994cited by this paper
• Signal transduction through the sphingomyelin pathway

  1994cited by this paper
• Neutral sphingomyelinase action stimulates signal transduction of tumor necrosis factor-alpha in the synthesis of cholesteryl esters in human fibroblasts.

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• The sphingomyelin cycle and the second messenger function of ceramide.

  1994cited by this paper
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• Inhibition of glycoprotein traffic through the secretory pathway by ceramide.

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• Sphingomyelinases.

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  1992cited by this paper
• Interleukin-1-mediated PGE2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide.

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• Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system.

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  1983cited by this paper
• Localization of neutral magnesium-stimulated sphingomyelinase in plasma membrane of cultured neuroblastoma cells.

  1982cited by this paper
• Assay of enzymes of lipid metabolism with colored and fluorescent derivatives of natural lipids.

  1981cited by this paper
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  1979cited by this paper
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  2011influential citation
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• Ceramide and Ceramide 1-Phosphate Are Negative Regulators of TNF-α Production Induced by Lipopolysaccharide

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• Ceramide-1-phosphate in phagocytosis and calcium homeostasis.

  2010cites this paper
• Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells

  2009cites this paper
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  2008cites this paper
• FcγRII Activation Induces Cell Surface Ceramide Production which Participates in the Assembly of the Receptor Signaling Complex

  2007cites this paper
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  2005cites this paper
• Ceramide 1-Phosphate, a Mediator of Phagocytosis*

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