Apoptosis Regulation of the ' ' Sphingomyelin Cycle ' ' in Fas-Induced Increase of Nuclear Ceramide through Caspase-3-Dependent

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Control of ceramide-induced apoptosis by IGF-1: involvement of PI-3 kinase, caspase-3 and catalase

  2002cited by this paper
• Increase of ceramide in adriamycin-induced HL-60 cell apoptosis: detection by a novel anti-ceramide antibody.

  2002influential reference
• Localization of the Lectin, ERp57 Binding, and Polypeptide Binding Sites of Calnexin and Calreticulin*

  2002cited by this paper
• Acid sphingomyelinase-derived ceramide signaling in apoptosis.

  2002cited by this paper
• Increase of phosphoinositide hydrolysis and diacylglycerol production by PAF in isolated rat liver nuclei.

  2001cited by this paper
• Ceramide glycosylation potentiates cellular multidrug resistance

  2001cited by this paper
• Activation of a nuclear sphingomyelinase in radiation induced apoptosis

  2001cited by this paper
• Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA‐N‐1 neuroblastoma cells: a key role for diacylglycerol

  2001cited by this paper
• Nuclear localization and signalling activity of inositol lipids.

  2001cited by this paper
• Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis.

  2001cited by this paper
• Ceramide regulates cellular homeostasis via diverse stress signaling pathways

  2001cited by this paper
• FAS Activation Induces Dephosphorylation of SR Proteins DEPENDENCE ON THE DE NOVO GENERATION OF CERAMIDE AND ACTIVATION OF PROTEIN PHOSPHATASE 1*

  2001cited by this paper
• Role of Ceramide in Mediating the Inhibition of Telomerase Activity in A549 Human Lung Adenocarcinoma Cells*

  2001cited by this paper
• Induction of Apoptosis through B-cell Receptor Cross-linking Occurs via de Novo Generated C16-Ceramide and Involves Mitochondria*

  2001cited by this paper
• Review: nuclear events in apoptosis.

  2000cited by this paper
• Insulin selectively stimulates nuclear phosphoinositide‐specific phospholipase C (PI‐PLC) β1 activity through a mitogen‐activated protein (MAP) kinase‐dependent serine phosphorylation

  2000cited by this paper
• Ceramide in the eukaryotic stress response.

  2000cited by this paper
• Morphological Changes in the Nucleus and Actin Cytoskeleton in the Process of Fas-induced Apoptosis in Jurkat T Cells

  2000cited by this paper
• Differential Effects of Sphingomyelin Hydrolysis and Resynthesis on the Activation of NF-κB in Normal and SV40-transformed Human Fibroblasts*

  2000cited by this paper
• Suppression of Heat Shock Protein-70 by Ceramide in Heat Shock-induced HL-60 Cell Apoptosis*

  2000cited by this paper
• Nuclear Lipid Signaling

  2000cited by this paper
• Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase

  1999cited by this paper
• Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis.

  1999cited by this paper
• Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma.

  1999cited by this paper
• Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis.

  1999cited by this paper
• A possible role of nuclear ceramide and sphingosine in hepatocyte apoptosis in rat liver.

  1999cited by this paper
• Identification of Regulatory and Catalytic Domains in the Apoptosis Nuclease DFF40/CAD*

  1999cited by this paper
• Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.

  1999cited by this paper
• Caspases: their intracellular localization and translocation during apoptosis

  1999influential reference
• Phosphatidylcholine-dependent phospholipase C in rat liver chromatin.

  1999cited by this paper
• Glucosylceramide synthase activity in murine epidermis: quantitation, localization, regulation, and requirement for barrier homeostasis.

  1998cited by this paper
• Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death*

  1998cited by this paper
• Diversity and complexity of ceramide signalling in apoptosis.

  1998cited by this paper
• CD95 (Fas/APO-1) Induces Ceramide Formation and Apoptosis in the Absence of a Functional Acid Sphingomyelinase*

  1998cited by this paper
• Sphingomyelin Synthase, a Potential Regulator of Intracellular Levels of Ceramide and Diacylglycerol during SV40 Transformation

  1998cited by this paper
• Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis*

  1998cited by this paper
• Regulation of ceramide production and apoptosis.

  1998cited by this paper
• Nuclear Diacylglycerol Produced by Phosphoinositide-specific Phospholipase C Is Responsible for Nuclear Translocation of Protein Kinase C-α*

  1998cited by this paper
• Acidic Sphingomyelinase (ASM) Is Necessary for Fas-induced GD3 Ganglioside Accumulation and Efficient Apoptosis of Lymphoid Cells

  1998cited by this paper
• The role of ceramide in the cellular response to cytotoxic agents.

  1998cited by this paper
• Bcl-2 expression causes redistribution of glutathione to the nucleus.

  1998cited by this paper
• Induction of a Caspase-3-like Activity by Calcium in Normal Cytosolic Extracts Triggers Nuclear Apoptosis in a Cell-free System*

  1998cited by this paper
• Activation of a plasma membrane-associated neutral sphingomyelinase and concomitant ceramide accumulation during IgG-dependent phagocytosis in human polymorphonuclear leukocytes.

  1998cited by this paper
• Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo.

  1998cited by this paper
• Tumor Necrosis Factor Induces Ceramide Oscillations and Negatively Controls Sphingolipid Synthases by Caspases in Apoptotic Kym-1 Cells*

  1998cited by this paper
• Nuclear sphingomyelin protects RNA from RNase action

  1998cited by this paper
• TNF Receptor Death Domain-associated Proteins TRADD and FADD Signal Activation of Acid Sphingomyelinase*

  1998cited by this paper
• Caspases: killer proteases.

  1997cited by this paper
• Influence of L-carnitine on CD95 cross-lining-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomyelinases in vitro.

  1997cited by this paper
• CD95/Fas-induced Ceramide Formation Proceeds with Slow Kinetics and Is Not Blocked by Caspase-3/CPP32 Inhibition*

  1997cited by this paper
• Caspases: the executioners of apoptosis.

  1997cited by this paper
• Ceramide-induced Translocation of Protein Kinase C-δ and -ε to the Cytosol

  1997cited by this paper
• Expression of Neutral Sphingomyelinase Identifies a Distinct Pool of Sphingomyelin Involved in Apoptosis*

  1997cited by this paper
• High levels of expression and nuclear localization of interleukin-1 beta converting enzyme (ICE) and CPP32 in favorable human neuroblastomas.

  1997cited by this paper
• Inhibition of the Neutral Magnesium-dependent Sphingomyelinase by Glutathione*

  1997cited by this paper
• (1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase (*)

  1996cited by this paper
• FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.

  1996cited by this paper
• Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

  1996cited by this paper
• Cell‐free reconstitution of Fas‐, UV radiation‐ and ceramide‐induced apoptosis.

  1995cited by this paper
• Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle.

  1994cited by this paper
• The novel second messenger ceramide: identification, mechanism of action, and cellular activity.

  1993cited by this paper
• Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation.

  1989cited by this paper
• ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

  1974cited by this paper
• Analytical Study of Microsomes and Isolated Subcellular Membranes from Rat Liver I. Biochemical Methods

  1974cited by this paper
• ISOLATION OF A GOLGI APPARATUS-RICH FRACTION FROM RAT LIVER

  1971cited by this paper

• Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells

  2022cites this paper
• Regulation of Death Receptor Signaling by S-Palmitoylation and Detergent-Resistant Membrane Micro Domains—Greasing the Gears of Extrinsic Cell Death Induction, Survival, and Inflammation

  2021cites this paper
• Modulation of DNA Damage Response by Sphingolipid Signaling: An Interplay that Shapes Cell Fate

  2020cites this paper
• Role of Ceramide / Sphingomyelin Balance Regulated by Sphingomyelin Synthases ( SMSs ) in Murine Disease Models

  2020cites this paper
• Ceramide/Sphingomyelin Rheostat Regulated by Sphingomyelin Synthases and Chronic Diseases in Murine Models

  2020cites this paper
• The miR-185/PAK6 Axis Predicts Therapy Response and Regulates Survival of Drug-Resistant Leukemic Stem Cells in CML.

  2020cites this paper
• Approaches for probing and evaluating mammalian sphingolipid metabolism.

  2019cites this paper
• Sphingomyelin synthase 2 promotes an aggressive breast cancer phenotype by disrupting the homoeostasis of ceramide and sphingomyelin

  2019cites this paper
• Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine‐1‐phosphate signaling in epigenetic regulation of inflammation and gene expression

  2018cites this paper
• Bcr‐Abl regulation of sphingomyelin synthase 1 reveals a novel oncogenic‐driven mechanism of protein up‐regulation

  2018cites this paper
• Geno- and cytotoxicity induced on Cyprinus carpio by aluminum, iron, mercury and mixture thereof.

  2017cites this paper
• Role of Sphingolipids in Death Receptor Signalling

  2017cites this paper
• Method to Measure Sphingomyelin Synthase Activity Changes in Response to CD95L.

  2017cites this paper
• Augmentation of Curcumin Induced Cell Death by Cell Permeable C2 Ceramide in Human T-lymphoma Jurkat Cell Line

  2016cites this paper
• Nuclear Lipids in the Nervous System: What they do in Health and Disease

  2016cites this paper
• TAMOXIFENO NO TRATAMENTO DE LEISHMANIOSE: ATIVIDADE EM ESQUEMAS TERAPÊUTICOS COMBINADOS E ESTUDO DO MECANISMO DE AÇÃO

  2015cites this paper
• Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies

  2015cites this paper
• Basics of Sphingolipid Metabolism and Signalling

  2015cites this paper
• Evolving concepts in cancer therapy through targeting sphingolipid metabolism.

  2014cites this paper
• The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration-from cell and animal models to human disorders.

  2014cites this paper
• Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling

  2014cites this paper
• Green tea polyphenols protect spinal cord neurons against hydrogen peroxide-induced oxidative stress

  2014cites this paper
• A new, long-wavelength borondipyrromethene sphingosine for studying sphingolipid dynamics in live cells[S]

  2013cites this paper
• Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogene[S]

  2013cites this paper
• Sphingolipids in apoptosis.

  2012cites this paper
• Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro.

  2012cites this paper
• Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.

  2012cites this paper
• Noninvasive application of alternating electric fields in glioblastoma: a fourth cancer treatment modality.

  2012cites this paper
• Nuclear sphingolipid metabolism.

  2012influential citation
• Molecular cloning, sequence characterization, and tissue expression analysis of chicken sphingomyelin synthase 1 (SMS1)

  2011cites this paper
• Glutathione selectively inhibits Doxorubicin induced phosphorylation of p53Ser¹⁵, caspase dependent ceramide production and apoptosis in human leukemic cells.

  2011cites this paper
• Sphingolipid metabolism and leukemia: a potential for novel therapeutic approaches.

  2011cites this paper
• Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)

  2011cites this paper
• Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation*

  2011cites this paper
• Cancer treatment strategies targeting sphingolipid metabolism.

  2010cites this paper
• L'inhibition de la voie Phosphoinositide-3 kinase (PI3K)/AKT induit un signal apoptotique via la redistribution du récepteur de mort CD95 dans les radeaux lipidiques

  2010cites this paper
• Roles of Neutral Sphingomyelinase 1 on CD95-Mediated Apoptosis in Human Jurkat T Lymphocytes

  2010cites this paper
• Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death

  2010cites this paper
• Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells.

  2009cites this paper
• Overexpression of human acid ceramidase precursor and variants of the catalytic center in Sf 9 cells

  2009cites this paper
• Ceramide production associated with retinal apoptosis after retinal detachment

  2009cites this paper
• Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.

  2008cites this paper
• Phosphatidylcholine/sphingomyelin metabolism crosstalk inside the nucleus.

  2008cites this paper
• GD3 nuclear localization after apoptosis induction in HUT-78 cells.

  2008cites this paper
• Lipid microdomains in cell nucleus.

  2008cites this paper
• Sphingolipid metabolites selectively elicit increases in nuclear calcium concentration in cell suspension cultures and in isolated nuclei of tobacco.

  2008cites this paper
• The interaction of adenovirus E1A with p300 family members modulates cellular gene expression to reduce tumorigenicity

  2007influential citation
• Interactions between neural membrane glycerophospholipid and sphingolipid mediators: A recipe for neural cell survival or suicide

  2007cites this paper
• Cloning, characterization, expression and comparative analysis of pig Golgi membrane sphingomyelin synthase 1.

  2007cites this paper
• Rôle des caspases et des sphingolipides dans la signalisation cytotoxique du récepteur FAS dans les lymphocytes T

  2007influential citation
• Development and characterization of a novel anti-ceramide antibody Published, JLR Papers in Press, January 8, 2007.

  2007cites this paper
• Sphingolipids as modulators of cancer cell death: potential therapeutic targets.

  2006cites this paper
• Molecular requirements for doxorubicin-mediated death in murine oocytes

  2006cites this paper
• Intracellular trafficking of sphingolipids: relationship to biosynthesis.

  2006cites this paper
• Protein Kinase C-induced Activation of a Ceramide/Protein Phosphatase 1 Pathway Leading to Dephosphorylation of p38 MAPK*

  2006cites this paper
• Cell death signalling pathways in the pathogenesis and therapy of haematologic malignancies: overview of apoptotic pathways.

  2006cites this paper
• Metabolizing Enzymes Such As Sphingomyelin Synthase Induce Cell Death by Increasing Ceramide Content

  2006cites this paper
• The mouse sphingomyelin synthase 1 (SMS1) gene is alternatively spliced to yield multiple transcripts and proteins.

  2005cites this paper
• Acid sphingomyelinase in macrophage apoptosis

  2004cites this paper
• Role of Ceramides in Skin Stress: Ultraviolet Light, Tape Stripping and Crowding

  2004cites this paper
• Expression Cloning of a Human cDNA Restoring Sphingomyelin Synthesis and Cell Growth in Sphingomyelin Synthase-defective Lymphoid Cells*

  2004cites this paper
• Biologically active sphingolipids in cancer pathogenesis and treatment

  2004cites this paper
• The complex life of simple sphingolipids

  2004cites this paper