Age-dependent changes of airway and lung parenchyma in C57BL/6J mice.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of applied physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/JAPPLPHYSIOL.00400.2006PMID 16946023
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Normal values for respiratory resistance using forced oscillation in subjects >65 years old

  2005cited by this paper
• Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling.

  2005cited by this paper
• Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione

  2005cited by this paper
• Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling

  2005cited by this paper
• Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue.

  2005cited by this paper
• Biomechanics of the lung parenchyma: critical roles of collagen and mechanical forces.

  2005cited by this paper
• Normal ageing of the lung: implications for diagnosis and monitoring of asthma in older people

  2005cited by this paper
• Impact of postnatal glucocorticoids on early lung development.

  2005cited by this paper
• Developmental changes in airway and tissue mechanics in mice.

  2005cited by this paper
• Differences in alveolar size in inbred mouse strains.

  2004cited by this paper
• Pathophysiology of airflow limitation in chronic obstructive pulmonary disease.

  2004cited by this paper
• Volume dependence of airway and tissue impedances in mice.

  2003influential reference
• Geometric determinants of airway resistance in two isomorphic rodent species.

  2002cited by this paper
• Elastic fibres.

  2002cited by this paper
• Viscoelasticity of the vessel wall: the role of collagen and elastic fibers.

  2001cited by this paper
• Physiological changes in respiratory function associated with ageing.

  1999cited by this paper
• Age-associated changes in elastin and collagen content and the proportion of types I and III collagen in the lungs of mice.

  1999cited by this paper
• Physiological changes in respiratory function associated with ageing.

  1999cited by this paper
• Geriatric respiratory medicine.

  1998cited by this paper
• Architecture, elastic fiber, and collagen in the distal air portion of the lung of the 18‐month‐old rat

  1997cited by this paper
• Chronic lung injury in preterm lambs: disordered pulmonary elastin deposition.

  1997cited by this paper
• Size‐dependent morphology of the conductive bronchial tree in four species of myomorph rodents

  1996cited by this paper
• Age-related changes in the static and dynamic mechanical properties of mouse lungs.

  1995cited by this paper
• Mechanical interdependence in relation to age: effects of lung volume on airway resistance in rats.

  1994cited by this paper
• Effects of low work function metals on the barrier height of sulfide‐treated n‐type GaAs(100)

  1992cited by this paper
• Input impedance and peripheral inhomogeneity of dog lungs.

  1992cited by this paper
• Spatial distribution of collagen and elastin fibers in the lungs.

  1990cited by this paper
• Connective tissue in aging lung.

  1983cited by this paper
• Age-related changes in elastic fibers and elastin of lung.

  1979cited by this paper
• Sex and age differences in pulmonary mechanics in normal nonsmoking subjects.

  1976cited by this paper
• Lung collagen composition and synthesis. Characterization and changes with age.

  1974cited by this paper
• [Mechanical properties of the lungs].

  1971influential reference
• Elasticity of human lungs in relation to age.

  1968cited by this paper
• Effect of age, sex, stature, and smoking habits on human airway conductance.

  1966cited by this paper
• Mechanical properties of lungs.

  1961cited by this paper
• Studies on the collagen and elastin content of the human lung.

  1960cited by this paper
• The relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size.

  1958cited by this paper
• The mechanical behavior of the lungs in healthy elderly persons.

  1957cited by this paper

• Micromechanics of lung capillaries across mouse lifespan and in positive- vs negative-pressure ventilation

  2025cites this paper
• Burden of Chronic Obstructive Pulmonary Disease in China: A Global Burden of Disease Study on Temporal Trends, Risk Factor Contributions, and Projected Disease Burden from 1990 to 2030

  2025cites this paper
• Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

  2025cites this paper
• Micromechanics of lung capillaries across mouse lifespan and in positive- vs negative-pressure ventilation

  2025cites this paper
• Fibrotic and emphysematous murine lung mechanics under negative-pressure ventilation

  2025cites this paper
• Effects of aging on the biomechanical properties of the lung extracellular matrix: dependence on tissular stretch

  2024cites this paper
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  2024cites this paper
• Quantitative micro-CT-derived biomarkers elucidate age-related lung fibrosis in elder mice

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• Aging, brain-derived neurotrophic factor, and allergen-induced pulmonary responses in mice.

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• Central and peripheral mechanisms underlying respiratory deficits in a mouse model of accelerated senescence

  2024cites this paper
• Endoplasmic Reticulum Stress Induced Senescence in Human Lung Fibroblasts.

  2024cites this paper
• Age-associated Differences in the Human Lung Extracellular Matrix.

  2023cites this paper
• Exercise evaluation with metabolic and ventilatory responses and blood lactate concentration in mice.

  2023cites this paper
• Similarities and differences in kinetic characteristics of airways inflammation, formation of inducible bronchial-associated lymphoid tissue and remodeling between young and old murine asthma surrogates induced with house dust mite.

  2023cites this paper
• A Comparative Study of Ex-Vivo Murine Pulmonary Mechanics Under Positive- and Negative-Pressure Ventilation

  2023cites this paper
• Immunosenescence, Inflammaging, and Lung Senescence in Asthma in the Elderly

  2022cites this paper
• A novel computed tomography radiomic nomogram for early evaluation of small airway dysfunction development

  2022cites this paper
• Neural correlate of reduced respiratory chemosensitivity during chronic epilepsy

  2022cites this paper
• Remodeling of the Aged and Emphysematous Lungs: Roles of Microenvironmental Cues.

  2022cites this paper
• Poor Reporting Quality in Basic Nutrition Research: A Case Study Based on a Scoping Review of Recent Folate Research in Mouse Models (2009-2021).

  2022cites this paper
• Respiratory mechanics following chronic cigarette smoke exposure in the Apoe-/-\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{do

  2022cites this paper
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  2022cites this paper
• An antioxidant suppressed lung cellular senescence and enhanced pulmonary function in aged mice.

  2021cites this paper
• Tenascin-C: Friend or Foe in Lung Aging?

  2021cites this paper
• Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging.

  2021cites this paper
• Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells

  2021cites this paper
• The Impact of the Synergistic Effect of Temperature and Air Pollutants on Chronic Lung Diseases in Subtropical Taiwan

  2021cites this paper
• Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema.

  2021cites this paper
• Reproducibility of animal research in light of biological variation

  2020cites this paper
• Distal lung epithelial progenitor cell function declines with age

  2020cites this paper
• Diaphragm muscle sarcopenia into very old age in mice

  2020cites this paper
• Quantitative morphology of the lung and its importance in investigations of pulmonary diseases in mice

  2019cites this paper
• The effects of aging and exercise on lung mechanics, surfactant and alveolar macrophages

  2019cites this paper
• Age-Related Structural and Functional Changes in the Mouse Lung

  2019cites this paper
• Stem Cells in Lungs.

  2019cites this paper
• Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a

  2019cites this paper
• Stem cell therapy in chronic obstructive pulmonary disease. How far is it to the clinic?

  2018cites this paper
• WNT pathway activation in COPD: a two way street between signalling and pathology

  2017cites this paper
• Noncanonical WNT signalling increases during ageing and induces alveolar damage

  2017cites this paper
• Middle age exacerbates acute respiratory distress syndrome in a double hit murine model

  2017influential citation
• Remodeling of the extracellular matrix in COPD. a process of accelerated lung ageing

  2017cites this paper
• Aging exacerbates acute lung injury-induced changes of the air-blood barrier, lung function, and inflammation in the mouse.

  2017cites this paper
• Aging effects on airflow dynamics and lung function in human bronchioles

  2017cites this paper
• Caractérisation de la sénescence des cardiomyocytes et identification de marqueurs associés

  2017cites this paper
• Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation

  2017cites this paper
• Morphometric analysis of the bronchiolar arterioles through the normal aging process

  2016cites this paper
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  2016cites this paper
• Regeneration of the Aging Lung: A Mini-Review

  2016cites this paper
• Mechanisms of lung aging

  2016cites this paper
• Elimination of p19ARF-expressing cells enhances pulmonary function in mice.

  2016cites this paper
• Aging-related changes in respiratory system mechanics and morphometry in mice.

  2016cites this paper
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  2016cites this paper
• Comprehensive assessment and characterization of pulmonary acinar morphometry using multi-resolution micro x-ray computed tomography

  2016cites this paper
• The molecular and mechanical mechanisms of the age-associated increase in the severity of experimental ventilator induced lung injury

  2016cites this paper
• Conservative fluid management prevents age-associated ventilator induced mortality.

  2016cites this paper
• Biomechanics of the Aging Lung Parenchyma

  2015cites this paper
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  2015cites this paper
• Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis.

  2015cites this paper
• Physiological parameters of the isolated perfused mouse lung and their dependency on age

  2015cites this paper
• Regenerative Cells in the Ageing Lung

  2015cites this paper
• Comparative Biology of the Normal Lung Extracellular Matrix

  2015cites this paper
• Aging of the normal lung

  2015cites this paper
• Aging and IPF: What Is the Link?

  2014cites this paper
• Normal Aging of the Lung

  2014cites this paper
• Analysis of Phenotype

  2014cites this paper
• Mouse Models to Explore the Aging Lung

  2014cites this paper
• 17β-estradiol replacement reverses age-related lung disease in estrogen-deficient C57BL/6J mice.

  2014cites this paper
• Remodeling of the Extracellular Matrix in the Aging Lung

  2014cites this paper
• Inflammation, advancing age and nutrition

  2014cites this paper
• Cellular Senescence and Premature Aging in Lung Diseases

  2014cites this paper
• Etude de déterminants de la dysfonction vasculaire pulmonaire au cours du syndrome de détresse respiratoire aigue

  2014cites this paper
• Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes

  2013cites this paper
• Vibration Analysis of Circular Membrane Model of Alveolar Wall in Examining Ultrasound-induced Lung Hemorrhage

  2013cites this paper
• Mesenchymal stem cell therapy in lung disorders: Pathogenesis of lung diseases and mechanism of action of mesenchymal stem cell

  2013cites this paper
• Age-related expression, enzymatic solubility and modification with advanced glycation end-products of fibrillar collagens in mouse lung.

  2013cites this paper
• Altered Th1/Th2 commitment contributes to lung senescence in CXCR3-deficient mice.

  2013cites this paper
• Enabling hyperpolarized 129Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin

  2013cites this paper
• Reduced expression level of the cyclic adenosine monophosphate response element-binding protein contributes to lung aging.

  2013cites this paper
• Theoretical Calculation of Bending Stiffness of Alveolar Wall

  2013cites this paper
• Aging does not Enhance Experimental Cigarette Smoke-Induced COPD in the Mouse

  2013cites this paper
• The receptor for advanced glycation end-products supports lung tissue biomechanics.

  2013cites this paper
• Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using multiscale microcomputed tomography

  2012cites this paper
• The effects of age and carbon black on airway resistance in mice

  2012cites this paper
• Sub-chronic exposure to second hand smoke induces airspace leukocyte infiltration and decreased lung elastance

  2012cites this paper
• Structural and stereological analysis of elastic fibers in the glans penis of young men.

  2012cites this paper
• Theoretical Modelling of Alveolar Resonance Mechanism of Ultrasound-Induced Lung Haemorrhage

  2012cites this paper
• Structural and stereological analysis of elastic fibers in the glans penis of young men

  2012cites this paper
• Critical Transition in Tissue Homeostasis Accompanies Murine Lung Senescence

  2011cites this paper
• Age-induced augmentation of p38 MAPK phosphorylation in mouse lung.

  2011cites this paper
• Differences in serotoninergic metabolism possibly contribute to differences in breathing phenotype of FVB/N and C57BL/6J mice.

  2011cites this paper
• Pulmonary function in aging humans

  2011cites this paper
• Exercise training enhances elastin, fibrillin and nitric oxide in the aorta wall of spontaneously hypertensive rats.

  2010cites this paper
• The Aging Lung and Cancer: Evidence of Field Cancerization from Transcriptional Profiles of Normal Human and Mouse Lung Tissues

  2010cites this paper
• Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity.

  2010cites this paper
• Aging and Interstitial Lung Diseases: Unraveling an Old Forgotten Player in the Pathogenesis of Lung Fibrosis

  2010cites this paper
• Effects of inhaled nitric oxide and surfactant with extracorporeal life support in recovery phase of septic acute lung injury in piglets.

  2010cites this paper
• Collagen Racemization and Deposition in the Lungs of Aged Rats

  2010cites this paper
• Aging and interstitial lung diseases: unraveling an old forgotten player in the pathogenesis of lung fibrosis.

  2010cites this paper
• Distribution and Quantity of Contractile Tissue in Postnatal Development of Rat Alveolar Interstitium

  2008cites this paper
• The bimodal quasi-static and dynamic elastance of the murine lung.

  2008cites this paper