Integrin-linked kinase and associated proteins (review).

No abstract is available for this paper.

• Publication year

  1999

• Venue

  International Journal of Molecular Medicine

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/IJMM.3.6.563PMID 10341284
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Interaction of the Integrin β1 Cytoplasmic Domain with ICAP-1 Protein*

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• Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.

  1998cited by this paper
• 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.

  1998cited by this paper
• Identification of p130Cas as a Mediator of Focal Adhesion Kinase–promoted Cell Migration

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• Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways.

  1998cited by this paper
• Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2.

  1998cited by this paper
• Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase*

  1998cited by this paper
• Identification of Nck Family Genes, Chromosomal Localization, Expression, and Signaling Specificity*

  1998cited by this paper
• Integrin signaling and cell growth control.

  1998cited by this paper
• ILK (β1-integrin-linked protein kinase): a novel immunohistochemical marker for Ewing’s sarcoma and primitive neuroectodermal tumour

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• Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology.

  1998cited by this paper
• Integrin-mediated signal transduction

  1998cited by this paper
• Phosphorylation and activation of p70s6k by PDK1.

  1998cited by this paper
• Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.

  1998cited by this paper
• Integrin-linked Protein Kinase Regulates Fibronectin Matrix Assembly, E-cadherin Expression, and Tumorigenicity*

  1998cited by this paper
• The Wiskott-Aldrich Syndrome Protein-interacting Protein (WIP) Binds to the Adaptor Protein Nck*

  1998cited by this paper
• Domain requirements for the Dock adapter protein in growth- cone signaling.

  1998cited by this paper
• TOR signalling and control of cell growth.

  1997cited by this paper
• PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond.

  1997cited by this paper
• Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

  1997cited by this paper
• Roles of integrins in fibronectin matrix assembly.

  1997cited by this paper
• NIK is a new Ste20‐related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

  1997cited by this paper
• Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

  1997cited by this paper
• Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor

  1997cited by this paper
• Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

  1997cited by this paper
• 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

  1997cited by this paper
• Overexpression of the Integrin-linked Kinase Promotes Anchorage-independent Cell Cycle Progression*

  1997cited by this paper
• Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

  1997cited by this paper
• Stabilization of beta-catenin by genetic defects in melanoma cell lines.

  1997cited by this paper
• Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

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• Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.

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• Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

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• Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

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• A Casein Kinase I Activity Is Constitutively Associated with Nck*

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• ICAP-1, a Novel β1 Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β1 Integrin

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• Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4.

  1997cited by this paper
• Signaling by Phosphoinositide-3,4,5-Trisphosphate Through Proteins Containing Pleckstrin and Sec7 Homology Domains

  1997cited by this paper
• Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase.

  1997cited by this paper
• Signalling through the lipid products of phosphoinositide-3-OH kinase

  1997cited by this paper
• A Comparative Analysis of the Phosphoinositide Binding Specificity of Pleckstrin Homology Domains*

  1997cited by this paper
• Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma

  1997cited by this paper
• Phosphoinositide 3-kinases: a conserved family of signal transducers.

  1997cited by this paper
• Cell adhesion: the molecular basis of tissue architecture and morphogenesis.

  1996cited by this paper
• Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

  1996cited by this paper
• The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration

  1996cited by this paper
• Integrin cytoplasmic interactions and bidirectional transmembrane signalling.

  1996cited by this paper
• Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein

  1996cited by this paper
• Anchorage-dependent transcription of the cyclin A gene

  1996cited by this paper
• The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

  1996cited by this paper
• Beta 1 integrin-dependent and -independent polymerization of fibronectin

  1996cited by this paper
• Structure and function of Cas-L, a 105-kD Crk-associated substrate- related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

  1996cited by this paper
• Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

  1996cited by this paper
• PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface.

  1996cited by this paper
• Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)*

  1996cited by this paper
• Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events

  1996cited by this paper
• Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

  1996cited by this paper
• GSK3: a SHAGGY frog story.

  1996cited by this paper
• The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

  1996cited by this paper
• Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly.

  1996cited by this paper
• Dependence of Cyclin E-CDK2 Kinase Activity on Cell Anchorage

  1996cited by this paper
• Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

  1996cited by this paper
• Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling*

  1996cited by this paper
• Thrombin stimulates association of src homology domain containing adaptor protein Nck with pp125FAK.

  1996cited by this paper
• Fibronectin fibrils and growth factors stimulate anchorage-independent growth of a murine mammary carcinoma.

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• Genomic imprinting in tumours.

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• Signal transduction through beta-catenin and specification of cell fate during embryogenesis.

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• Cadherins and catenins in development.

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• The E-cadherin/catenin complex in invasion and metastasis.

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• Identification of a new biological function for the integrin alpha v beta 3: initiation of fibronectin matrix assembly.

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• Interaction Between Wingless and Notch Signaling Pathways Mediated by Dishevelled

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• Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix

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• Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

  1995cited by this paper
• Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

  1995cited by this paper
• Integrins: emerging paradigms of signal transduction.

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• Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

  1995cited by this paper
• Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

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• Identification of a Mouse p21Cdc42/Rac Activated Kinase (*)

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• A Novel Ligand for SH3 Domains

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• Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit

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• Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.

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• Characterization of beta pat-3 heterodimers, a family of essential integrin receptors in C. elegans

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• Integrin transmembrane signaling and cytoskeletal control.

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• Binding of NCK to SOS and activation of ras-dependent gene expression

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• E-cadherin as an invasion suppressor.

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• Cadherin transfection of Xenopus XTC cells downregulates expression of substrate adhesion molecules

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• LIM domain proteins.

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• Integrins and signal transduction pathways: the road taken.

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• Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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• The enigma of LIM domains.

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• The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression.

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• Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C.

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• The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.

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• Dicing with death: dissecting the components of the apoptosis machinery.

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• Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.

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