Effect of Biomechanical Conditioning on Cartilaginous Tissue Formation in Vitro

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Bone and Joint Surgery. American volume

• Publication date

  2003-04-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.2106/00004623-200300002-00013PMID 12721351
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Long-Term Intermittent Compressive Stimulation Improves the Composition and Mechanical Properties of Tissue-Engineered Cartilage

  2004cited by this paper
• The use of specific chondrocyte populations to modulate the properties of tissue‐engineered cartilage

  2003cited by this paper
• Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro.

  2002cited by this paper
• The effect of dynamic compression on the response of articular cartilage to insulin‐like growth factor‐I

  2001cited by this paper
• Porous calcium polyphosphate scaffolds for bone substitute applications -- in vitro characterization.

  2001cited by this paper
• Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants.

  2001cited by this paper
• The influence of mechanical loading on isolated chondrocytes seeded in agarose constructs

  2000cited by this paper
• Mechanical quality of tissue engineered cartilage: results after 6 and 12 weeks in vivo.

  2000cited by this paper
• Effects of shear stress on articular chondrocyte metabolism

  2000cited by this paper
• Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels.

  2000influential reference
• A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants.

  2000cited by this paper
• The effects of high magnitude cyclic tensile load on cartilage matrix metabolism in cultured chondrocytes.

  2000cited by this paper
• Cartilage tissue remodeling in response to mechanical forces.

  2000cited by this paper
• Modulation of the mechanical properties of tissue engineered cartilage

  2000cited by this paper
• Mechanotransduction via integrins and interleukin-4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes.

  2000cited by this paper
• Influence of intermittent pressure, fluid flow, and mixing on the regenerative properties of articular chondrocytes.

  1999cited by this paper
• New horizons in the treatment of osteoarthritis of the knee.

  1999cited by this paper
• Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue‐engineered cartilage

  1999cited by this paper
• Articular cartilage repair: are the intrinsic biological constraints undermining this process insuperable?

  1999cited by this paper
• Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow.

  1999cited by this paper
• Response of chondrocyte subpopulations cultured within unloaded and loaded agarose

  1998cited by this paper
• Articular Cartilage Repair

  1998cited by this paper
• Synthesis of collagen by bovine chondrocytes cultured in alginate; posttranslational modifications and cell-matrix interaction.

  1997cited by this paper
• Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose

  1997cited by this paper
• Characterization of proteoglycan accumulation during formation of cartilagenous tissue in vitro.

  1995cited by this paper
• Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture.

  1995cited by this paper
• Effects of fluid‐induced shear on articular chondrocyte morphology and metabolism in vitro

  1995cited by this paper
• Mechanical regulation of cartilage biosynthetic behavior: physical stimuli.

  1994cited by this paper
• Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix

  1992cited by this paper
• An improved method for determining proteoglycans synthesized by chondrocytes in culture.

  1990cited by this paper
• Biosynthetic response of cartilage explants to dynamic compression

  1989cited by this paper
• Fluorometric assay of DNA in cartilage explants using Hoechst 33258.

  1988cited by this paper
• Effects of static and cyclic compressive loading on articular cartilage plugs in vitro.

  1984cited by this paper
• The Methodology of Connective Tissue Research

  1976cited by this paper

• New Biomaterials and Technologies in Growth Plate Regeneration

  2025cites this paper
• Rehabilitation of the Knee After Autologous Matrix-Induced Chondrogenesis: A Systematic Review of Rehabilitation Protocols and Clinical and Radiological Outcomes

  2025cites this paper
• Predicting the heterogeneous chemo-mechano-biological degeneration of cartilage using 3-D biphasic finite elements

  2025cites this paper
• Design of cyclic tissue engineering bioreactor based on alginate hydrogel responses to the stress of compression surface morphologies and texture profile and its finite element analysis.

  2025cites this paper
• A chemo-mechano-biological modeling framework for cartilage evolving in health, disease, injury, and treatment

  2023cites this paper
• Post-operative rehabilitation and nutrition in osteoarthritis [version 2; peer review: 2 approved with reservations]

  2022cites this paper
• TRPV4 activation enhances compressive properties and glycosaminoglycan deposition of equine neocartilage sheets

  2022cites this paper
• Generation of double-layered equine mesenchymal stromal cell-derived osteochondral constructs

  2022cites this paper
• Post-operative rehabilitation and nutrition in osteoarthritis [ version 3 ; peer review : 2 approved , 1 approved with reservations ]

  2022cites this paper
• Low magnitude high frequency vibration promotes chondrogenic differentiation of bone marrow stem cells with involvement of β-catenin signaling pathway.

  2020cites this paper
• Engineering functional tissues: in vitro culture parameters

  2020cites this paper
• 3D models of chondrocytes within biomimetic scaffolds: Effects of cell deformation from loading regimens.

  2020cites this paper
• Micromechanical Design Criteria for Tissue-Engineering Biomaterials

  2020cites this paper
• Are Weightbearing Restrictions Required After Microfracture for Isolated Chondral Lesions of the Knee? A Review of the Basic Science and Clinical Literature

  2020cites this paper
• A Novel Bioreactor System Capable of Simulating the In Vivo Conditions of Synovial Joints

  2020cites this paper
• The influence of hydrogel density and RGD in cartilage tissue engineering

  2019cites this paper
• Post-operative rehabilitation in osteoarthritis [version 1; peer review: awaiting peer review]

  2019cites this paper
• Cartilage Tissue Engineering

  2019cites this paper
• Influence of hydrodynamic pressure on chondrogenic differentiation of human bone marrow mesenchymal stem cells cultured in perfusion system.

  2018cites this paper
• Dynamic Mechanical Compression of Chondrocytes for Tissue Engineering: A Critical Review

  2017cites this paper
• 6.5 Biomaterials in Cartilage Tissue Engineering

  2017cites this paper
• Contact Forces Acting on Large Femoral Osteochondral Allografts During Forced Knee Extension

  2017cites this paper
• Impact of expansion and redifferentiation under hypothermia on chondrogenic capacity of cultured human septal chondrocytes

  2017cites this paper
• 33 – Rehabilitation After Articular Cartilage Procedures

  2017cites this paper
• Sol gel-derived hydroxyapatite films over porous calcium polyphosphate substrates for improved tissue engineering of osteochondral-like constructs.

  2017cites this paper
• Rehabilitation Principles of the Anterior Cruciate Ligament Reconstructed Knee: Twelve Steps for Successful Progression and Return to Play.

  2017cites this paper
• Finding the Links between Knee Injuries and Osteoarthritis

  2016cites this paper
• Post-operative rehabilitation and nutrition in osteoarthritis

  2016cites this paper
• Mechanical stimulation enhances integration in an in vitro model of cartilage repair

  2016cites this paper
• No difference in outcome between early versus delayed weight-bearing following microfracture surgery of the hip, knee or ankle: a systematic review of outcomes and complications

  2016cites this paper
• The sensitivity of articular chondrocytes to dynamic mechanical stimulation

  2016cites this paper
• The role of mechanical loading in chondrocyte signaling pathways

  2016cites this paper
• Post-operative rehabilitation in osteoarthritis [ version 1 ; referees : awaiting peer review ]

  2016cites this paper
• Post-operative rehabilitation and nutrition in osteoarthritis.

  2015cites this paper
• Mechanobioreactors for Cartilage Tissue Engineering.

  2015cites this paper
• Developing an In vitro Model of the OAF-CEP Interface: Towards Tissue Engineering the Intervertebral Disc

  2015cites this paper
• Current Concepts in Hip Preservation Surgery

  2015cites this paper
• Mechanotransduction: Relevance to Physical Therapist Practice—Understanding Our Ability to Affect Genetic Expression Through Mechanical Forces

  2015cites this paper
• Development and analysis of apatite-mullite glass-ceramic scaffolds : towards tissue engineering of the vertebral endplate

  2014cites this paper
• Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis. A narrative review.

  2014cites this paper
• Functional outcomes after surgical management of articular cartilage lesions in the knee: a systematic literature review to guide postoperative rehabilitation.

  2014cites this paper
• Design and validation of an in vitro loading system for the combined application of cyclic compression and shear to 3D chondrocytes-seeded agarose constructs.

  2014cites this paper
• Scaffold-based regeneration of skeletal tissues to meet clinical challenges.

  2014cites this paper
• Post-operative rehabilitation in osteoarthritis.

  2014cites this paper
• Techniques in Cartilage Repair Surgery

  2014cites this paper
• Mechanical and Hydromechanical Stimulation of Chondrocytes for Articular Cartilage Tissue Engineering

  2014cites this paper
• Recherche translationnelle appliquée au cartilage : approche multifactorielle combinant chondrocytes humains, facteurs de différenciation, biomatériaux et bioréacteurs pour la reconstruction du cartilage hyalin

  2014cites this paper
• Post-operative rehabilitation and nutrition in osteoarthritis.

  2014cites this paper
• Bioglass®/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering.

  2014cites this paper
• Rehabilitation After Cartilage Repair Surgery: Part II Practical Issues

  2014cites this paper
• Management strategies for osteochondritis dissecans of the knee in the skeletally immature athlete.

  2014cites this paper
• Development and validation of a microfluidic hydrogel platform for osteochondral tissue engineering

  2014cites this paper
• Micromechanical Design Criteria for Tissue Engineering Biomaterials

  2013cites this paper
• Poly(ε-caprolactone)-based copolymers bearing pendant cyclic ketals and reactive acrylates for the fabrication of photocrosslinked elastomers.

  2013cites this paper
• Synthesis of hyaluronan and superficial zone protein in synovial membrane cells modulated by fluid flow.

  2013cites this paper
• Biomechanical properties and mechanobiology of the articular chondrocyte.

  2013cites this paper
• Resorbable polymers for medical applications

  2013cites this paper
• Bioreactors for evaluating cell infiltration and tissue formation in biomaterials

  2013cites this paper
• Supplementation with platelet-rich plasma improves the in vitro formation of tissue-engineered cartilage with enhanced mechanical properties.

  2013cites this paper
• The incorporation of a zone of calcified cartilage improves the interfacial shear strength between in vitro-formed cartilage and the underlying substrate.

  2012cites this paper
• Recent advances in the rehabilitation of anterior cruciate ligament injuries.

  2012cites this paper
• Effects of Perfusion and Dynamic Loading on Human Neocartilage Formation in Alginate Hydrogels

  2012cites this paper
• Inorganic Polyphosphate Stimulates Cartilage Tissue Formation

  2012cites this paper
• Toward Engineering a Biological Joint Replacement

  2012cites this paper
• Engineering Complex Tissues

  2012cites this paper
• A crimp-like microarchitecture improves tissue production in fibrous ligament scaffolds in response to mechanical stimuli.

  2012cites this paper
• Mechano-Active Scaffolds

  2012cites this paper
• Fabrication of composite scaffolds impregnated with an optimized fibrin-alginate hydrogel for cartilage tissue engineering

  2012cites this paper
• Integration of Tissue-engineered Cartilage – An In Vitro Model

  2012cites this paper
• Bioreactor cultivation and remodelling simulation for cartilage replacement material.

  2012cites this paper
• Creating a Living Hyaline Cartilage Graft Free from Non‐Cartilaginous Constituents: An Intermediate Role of a Biomaterial Scaffold

  2012cites this paper
• Solid Freeform Fabrication of Porous Calcium Polyphosphate Structures for Use in Orthopaedics

  2011cites this paper
• Hydrodynamics in Porous Media with Applications to Tissue Engineering

  2011cites this paper
• Effect of freezing on rabbit cultured chondrocytes

  2011cites this paper
• Phase transfer cell culture system for self-forming cartilage tissue regeneration

  2011cites this paper
• Physiological cartilage tissue engineering effect of oxygen and biomechanics.

  2011cites this paper
• Design and validation of a bi-axial loading bioreactor for mechanical stimulation of engineered cartilage.

  2011cites this paper
• Arthroplasty of the lunate using bone marrow mesenchymal stromal cells

  2011cites this paper
• Effect of freezing on rabbit cultured chondrocytes

  2011cites this paper
• 5.516 – Biomaterials in Cartilage Tissue Engineering

  2011cites this paper
• Cartilage tissue engineering.

  2011cites this paper
• Poroelastic Finite Element Analysis of a Heterogeneous Articular Cartilage Explant Under Dynamic Compression in ABAQUS

  2011cites this paper
• Chapter 53 – Cartilage Tissue Engineering

  2011cites this paper
• USING ADENOSINE TRIPHOSPHATE (ATP) AS A SUBSTITUTE FOR MECHANICAL STIMULATION FOR TISSUE ENGINEERING APPLICATIONS

  2011cites this paper
• Mechanical Properties of Natural Cartilage and Tissue-Engineered Constructs

  2011cites this paper
• Matrix accumulation by articular chondrocytes during mechanical stimulation is influenced by integrin-mediated cell spreading.

  2010cites this paper
• The Effect of Intermittent Static Biaxial Tensile Strains on Tissue Engineered Cartilage

  2010cites this paper
• Advances in Tissue Engineering Techniques for Articular Cartilage Repair.

  2010cites this paper
• Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1‐MMP

  2010cites this paper
• Rehabilitation following Microfracture of the Knee

  2010cites this paper
• Magnetic Resonance Studies of Macromolecular Content in Engineered Cartilage Treated with Pulsed Low-Intensity Ultrasound

  2010cites this paper
• 2010 Nicolas Andry Award: Multipotent Adult Stem Cells from Adipose Tissue for Musculoskeletal Tissue Engineering

  2010cites this paper
• Effects Of Physical Stimuli On Extracellular Matrix Assembly By Chondrocytes And Mesenchymal Stem Cells: Experimental And Finite Element Analyses

  2010cites this paper
• Measuring the biomechanical properties of cartilage cells

  2010cites this paper
• Modulation of connective tissue stromal cell plasticity to generate cartilaginous phenotypes

  2010cites this paper
• Development of a Novel Porogen Insertion System Used in Solid Freeform Fabrication of Porous Biodegradable Scaffolds with Heterogeneous Internal Architectures

  2010cites this paper
• Dynamic cell culture methods for functionalized biomaterials

  2010cites this paper
• Nanocomposites for Regenerative Medicine

  2010cites this paper
• A Therapeutic Dose of Adenosine Triphosphate (ATP) for Cartilage Tissue Engineering

  2010influential citation
• A novel biomimetic polymer scaffold design enhances bone ingrowth.

  2009cites this paper