Regular articles: conditional disruption of hedgehog signaling pathway defines its critical role in hair development and regeneration.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Investigative Dermatology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10771469
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1998cited by this paper
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  1998cited by this paper
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• Characterization of two patched receptors for the vertebrate hedgehog protein family.

  1998cited by this paper
• Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

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  1997cited by this paper
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  1997cited by this paper
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• The world according to hedgehog.

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• Transient absence of CD44 expression and delay in development by anti-CD44 treatment during ontogeny: a surrogate of an inducible knockout?

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• Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation

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• The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

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• smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

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• Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity.

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• The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal.

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• Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

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• Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth.

  1996cited by this paper
• Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate.

  1995cited by this paper
• Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing.

  1995cited by this paper
• Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development.

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• Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs

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• Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

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• Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

  1994cited by this paper
• Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.

  1993cited by this paper
• Hair follicles, stem cells, and skin cancer.

  1993cited by this paper
• Segregation of keratinocyte colony-forming cells in the bulge of the rat vibrissa.

  1993cited by this paper
• Interaction of trichohyalin with intermediate filaments: three immunologically defined stages of trichohyalin maturation.

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• Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis.

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• How to make a hybridoma.

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• A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila

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• Glandular metaplasia of hair follicles and other responses to vitamin A excess in cultures of rodent skin.

  1968cited by this paper

• Down-regulation of Shh in the hair follicles of mice during chemotherapy-induced hair loss is mediated by the JAK/STAT1 signaling pathway.

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• FGF22 Secreted by Hair Papilla Cells Regulates Hair Follicle Stem Cell Proliferation and Differentiation

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• Screening of hair follicle telogen-associated circRNAs in sheep and construction of their ceRNA network.

  2024cites this paper
• Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells

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• Small molecule agents against alopecia: Potential targets and related pathways.

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• A pig model exploring the postnatal hair follicle cycle

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• Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats

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• Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays.

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• Materials-based hair follicle engineering: Basic components and recent advances

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• Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche

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• Telogen effluvium: a 360 degree review.

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• The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles

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• A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits

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• Effect of Sonic Hedgehog on the Regeneration of Epidermal Texture Patterns

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• Effect of Sox18 on the Induction Ability of Dermal Papilla Cells in Hu Sheep

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• The Effects of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Smoking Behavior: An Ecological Momentary Assessment Study

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• Modeling of ionizing radiation induced hair follicle regenerative dynamics.

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• The Roles of Non-coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives

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• Zebrafish twist2/dermo1 regulates scale shape and scale organization during skin development and regeneration.

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• Progress on the Function and Application of Thymosin β4

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• Ginseng in Hair Growth and Viability

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• The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages

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• Azelaic acid stimulates catalase activation and promotes hair growth through upregulation of Gli1 and Gli2 mRNA and Shh protein

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• Inhibition of sonic hedgehog signaling via MAPK activation controls chemotherapy-induced alopecia.

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• Transcriptional Profiling of the Adult Hair Follicle Mesenchyme Reveals R-spondin as a Novel Regulator of Dermal Progenitor Function

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• Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species

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• Fibroblast Growth Factors Stimulate Hair Growth through β-Catenin and Shh Expression in C57BL/6 Mice

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• Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.

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• The disruption of a novel limb cis-regulatory element of SHH is associated with autosomal dominant preaxial polydactyly-hypertrichosis

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• Hair loss and Hedgehog inhibitors: a class effect?

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• Sonic hedgehog signaling in the lung. From development to disease.

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• Mapping the Shh regulatory landscape

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• Hedgehog Pathway Agonism: Therapeutic Potential and Small‐Molecule Development

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• Transit-amplifying cells orchestrate stem cell activity and tissue regeneration.

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• Roles for Hedgehog signaling in adult organ homeostasis and repair

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• Basal cell carcinoma, Hedgehog signaling, and targeted therapeutics: the long and winding road.

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• The Role of Hedgehog-Gli Pathway Regulators in Skin Development and Tumorigenesis

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• Role of aPKCl in epidermal morphogenesis and homeostasis

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• Epidermal Stem Cells in Orthopaedic Regenerative Medicine

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• Tumor–stroma interaction in orthotopic primary pancreatic cancer xenografts during hedgehog pathway inhibition

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• Ihh and Runx2/Runx3 Signaling Interact to Coordinate Early Chondrogenesis: A Mouse Model

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• Indian hedgehog controls proliferation and differentiation in skin tumorigenesis and protects against malignant progression.

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• Biochemistry of epidermal stem cells.

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• EGFR-Ras-Raf Signaling in Epidermal Stem Cells: Roles in Hair Follicle Development, Regeneration, Tissue Remodeling and Epidermal Cancers

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• Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration

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• Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity

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• Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair.

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• Hairy tale of signaling in hair follicle development and cycling.

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• Trps1 and Its Target Gene Sox9 Regulate Epithelial Proliferation in the Developing Hair Follicle and Are Associated with Hypertrichosis

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• Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling.

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• Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration

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• Shh signaling is essential for rugae morphogenesis in mice

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• Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth

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• Nevoid basal carcinoma syndrome (Gorlin syndrome) and pronounced androgenic alopecia in a woman with a novel mutation p.Leu1159fsx32 in the PTCH gene

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