Cardiac mitochondrial bioenergetics, oxidative stress, and aging.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  2007-06-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/AJPCELL.00285.2006PMID 17344313
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of caloric restriction and exercise on age-related, chronic inflammation assessed by C-reactive protein and interleukin-6.

  2006cited by this paper
• Biology of Aging

  2006cited by this paper
• Hepatic Oxidative Stress During Aging: Effects of 8% Long-Term Calorie Restriction and Lifelong Exercise

  2006cited by this paper
• TGF β1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells

  2005cited by this paper
• Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart.

  2005cited by this paper
• Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

  2005cited by this paper
• Tissue-specific changes of mitochondrial functions in aged rats: effect of a long-term dietary treatment with N-acetylcysteine.

  2005cited by this paper
• Age‐associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging

  2005influential reference
• Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging.

  2005cited by this paper
• Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria

  2005cited by this paper
• Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria.

  2005cited by this paper
• Exogenous insulin can reverse the effects of caloric restriction on mitochondria.

  2004cited by this paper
• Effect of insulin and growth hormone on rat heart and liver oxidative stress in control and caloric restricted animals

  2004cited by this paper
• Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart.

  2004cited by this paper
• Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer.

  2004cited by this paper
• Is defective electron transport at the hub of aging?

  2004cited by this paper
• The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption.

  2004cited by this paper
• Short-term CR decreases cardiac mitochondrial oxidant production but increases carbonyl content.

  2004cited by this paper
• Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts.

  2004cited by this paper
• Premature ageing in mice expressing defective mitochondrial DNA polymerase

  2004cited by this paper
• Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart.

  2003cited by this paper
• Effects of age and caloric restriction on glutathione redox state in mice.

  2003cited by this paper
• Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart.

  2003cited by this paper
• Protein kinase D mediates a stress‐induced NF‐κB activation and survival pathway

  2003cited by this paper
• The influence of endogenously generated reactive oxygen species on the inotropic and chronotropic effects of adrenoceptor and ET-receptor stimulation

  2003cited by this paper
• The biology of aging.

  2003cited by this paper
• Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.

  2003influential reference
• Overexpressed nuclear factor‐κB can participate in endogenous C‐reactive protein induction, and enhances the effects of C/EBPβ and signal transducer and activator of transcription‐3

  2003cited by this paper
• Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.

  2002cited by this paper
• Mitochondrial Decay in the Aging Rat Heart

  2002cited by this paper
• DNA microarray analysis of the aging brain.

  2002cited by this paper
• Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle

  2002cited by this paper
• Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age.

  2002cited by this paper
• Minireview: The Quantitative Measurement of H2O2 Generation in Isolated Mitochondria

  2002cited by this paper
• Endogenous oxidative stress: relationship to aging, longevity and caloric restriction.

  2002cited by this paper
• Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.

  2002cited by this paper
• Preservation of cardiolipin content during aging in rat heart interfibrillar mitochondria.

  2002cited by this paper
• Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress

  2002cited by this paper
• Generation of reactive oxygen species by the mitochondrial electron transport chain

  2002cited by this paper
• Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls.

  2002cited by this paper
• Role of Mitochondria in Oxidative Stress and Aging

  2002cited by this paper
• Role of oxidative stress and protein oxidation in the aging process.

  2002cited by this paper
• Gene expression profiling of the aging mouse cardiac myocytes.

  2002cited by this paper
• Aging Increases N epsilon -(Carboxymethyl)lysine and Caloric Restriction Decreases N epsilon -(Carboxyethyl)lysine and N epsilon -(Malondialdehyde)lysine in Rat Heart Mitochondrial Proteins

  2002cited by this paper
• Modulation of redox-sensitive transcription factors by calorie restriction during aging.

  2002cited by this paper
• Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice.

  2001cited by this paper
• Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats.

  2001cited by this paper
• Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)‐α‐lipoic acid

  2001cited by this paper
• The inflammation hypothesis of aging: molecular modulation by calorie restriction.

  2001cited by this paper
• Voluntary physical activity prevents stress-induced behavioral depression and anti-KLH antibody suppression.

  2001cited by this paper
• Reactive carbonyl formation by oxidative and non-oxidative pathways.

  2001influential reference
• Mitochondrial respiration at low levels of oxygen and cytochrome c.

  2001cited by this paper
• Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

  2001influential reference
• Aging decreases electron transport complex III activity in heart interfibrillar mitochondria by alteration of the cytochrome c binding site.

  2001influential reference
• Protein Oxidation in Aging and Age‐Related Diseases

  2001influential reference
• Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failure.

  2001cited by this paper
• Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

  2001cited by this paper
• Does oxidative damage to DNA increase with age?

  2001cited by this paper
• Voluntary and forced exercise influence the survival and body composition of ageing male rats differently.

  2001cited by this paper
• The Inflammation Hypothesis of Aging

  2001cited by this paper
• Treadmill running produces both positive and negative physiological adaptations in Sprague-Dawley rats.

  2000cited by this paper
• Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse.

  2000cited by this paper
• Free radical generation and oxidative stress with ageing and exercise: differential effects in the myocardium and liver.

  2000cited by this paper
• Aging is associated with increased lipid peroxidation in human hearts, but not with mitochondrial respiratory chain enzyme defects.

  2000cited by this paper
• Exercise preconditioning against hydrogen peroxide-induced oxidative damage in proteins of rat myocardium.

  2000cited by this paper
• Localization of dichlorofluorescin in cardiac myocytes: implications for assessment of oxidative stress.

  2000cited by this paper
• Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals

  2000influential reference
• 4-Hydroxy-2-nonenal-mediated Impairment of Intracellular Proteolysis during Oxidative Stress

  1999cited by this paper
• Aging and acute exercise enhance free radical generation in rat skeletal muscle.

  1999cited by this paper
• Effect of training on H(2)O(2) release by mitochondria from rat skeletal muscle.

  1999cited by this paper
• Aging selectively decreases oxidative capacity in rat heart interfibrillar mitochondria.

  1999influential reference
• Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria.

  1999cited by this paper
• Age-related increases of 8-hydroxy-2'-deoxyguanosine and DNA-protein crosslinks in mouse organs.

  1999cited by this paper
• Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine.

  1999cited by this paper
• The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes.

  1999cited by this paper
• Oxidized amino acids in the urine of aging rats: potential markers for assessing oxidative stress in vivo.

  1999cited by this paper
• Effect of Training on H2O2 Release by Mitochondria from Rat Skeletal Muscle

  1999cited by this paper
• Reduced mitochondrial DNA transcription in senescent rat heart.

  1998cited by this paper
• The free radical theory of aging matures.

  1998cited by this paper
• Mitochondrial respiration in the low oxygen environment of the cell. Effect of ADP on oxygen kinetics.

  1998cited by this paper
• Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations

  1998cited by this paper
• Longevity of exercising male rats: effect of an antioxidant supplemented diet.

  1998cited by this paper
• Effects of endurance physical training on hydroxyl radical generation in rat tissues.

  1998cited by this paper
• Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA.

  1998cited by this paper
• Mortality rate and longevity of food-restricted exercising male rats: a reevaluation.

  1997cited by this paper
• Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon.

  1997cited by this paper
• Mitochondrial Complex I defects in aging

  1997cited by this paper
• Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice.

  1997cited by this paper
• Physical activity, physical fitness and longevity

  1997cited by this paper
• Adaptations of glutathione antioxidant system to endurance training are tissue and muscle fiber specific.

  1997cited by this paper
• Inhibition of the multicatalytic proteinase (proteasome) by 4‐hydroxy‐2‐nonenal cross‐linked protein

  1997cited by this paper
• Age‐dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin

  1997cited by this paper
• Dependence of H2O2 Formation by Rat Heart Mitochondria on Substrate Availability and Donor Age

  1997cited by this paper
• ADP-Regulation of Mitochondrial Free Radical Production Is Different with Complex I- or Complex II-Linked Substrates: Implications for the Exercise Paradox and Brain Hypermetabolism

  1997cited by this paper
• Genetic and functional changes in mitochondria associated with aging.

  1997cited by this paper
• Oxidative Stress, Caloric Restriction, and Aging

  1996cited by this paper
• Mitochondrial glutathione oxidation correlates with age‐associated oxidative damage to mitochondrial DNA

  1996cited by this paper
• Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B.

  1996cited by this paper
• Exercise and diet modulate cardiac lipid peroxidation and antioxidant defenses.

  1996cited by this paper
• Influence of age, exercise, and dietary restriction on oxidative stress in rats

  1996cited by this paper

• Mitochondrial complex-1 as a therapeutic target for cardiac diseases

  2024cites this paper
• The role of CYP-sEH derived lipid mediators in regulating mitochondrial biology and cellular senescence: implications for the aging heart

  2024cites this paper
• Membrane Lipid Replacement and Its Role in Restoring Mitochondrial Membrane Function and Reducing Symptoms in Aging and Age-related Clinical Conditions

  2024cites this paper
• Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in Old Isolated Cardiac Mitochondria

  2024cites this paper
• SIRT6: A potential therapeutic target for diabetic cardiomyopathy

  2023cites this paper
• SGLT2 Inhibitors in Aging-Related Cardiovascular Disease: A Review of Potential Mechanisms

  2023cites this paper
• The effect of Centella asiatica ethanolic extract on liver superoxide dismutase and glutathione levels of aged Sprague-Dawley rats

  2022cites this paper
• Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study

  2022cites this paper
• Circulating Mitochondrial DNA and Inter-Organelle Contact Sites in Aging and Associated Conditions

  2022cites this paper
• PRUNETIN ATTENUATES D-GALACTOSE-INDUCED BRAIN AGING VIA INHIBITING AMYLOID-Β AND TAU PROTEIN AGGREGATION

  2022cites this paper
• Long-Term Aerobic Training Improves Mitochondrial and Antioxidant Function in the Liver of Wistar Rats Preventing Hepatic Age-Related Function Decline

  2022cites this paper
• Inorganic Polyphosphate, Mitochondria, and Neurodegeneration.

  2022cites this paper
• Physical exercise prevents age-related heart dysfunction induced by high-salt intake and heart salt-specific overexpression in Drosophila

  2021cites this paper
• Adipose tissue senescence is mediated by increased ATP content after a short‐term high‐fat diet exposure

  2021cites this paper
• Mitophagy: At the heart of mitochondrial quality control in cardiac aging and frailty.

  2021cites this paper
• Cardiomyocyte Senescence

  2021cites this paper
• Horse mushroom (Agaricus arvensis Schaeff.) prevents oxidative stress in carbon tetrachloride toxicity

  2021cites this paper
• mTOR inhibition improves mitochondria function/biogenesis and delays cardiovascular aging in kidney transplant recipients with chronic graft dysfunction

  2021cites this paper
• Developmental and lifelong dioxin exposure induces measurable changes in cardiac structure and function in adulthood

  2021cites this paper
• Mitochondria as a therapeutic target for cardiac ischemia-reperfusion injury (Review)

  2020cites this paper
• Cardiolipin, Perhydroxyl Radicals, and Lipid Peroxidation in Mitochondrial Dysfunctions and Aging

  2020cites this paper
• Mitochondrial Genetic Effect on Atrial Fibrillation: A Case-Control Study.

  2020cites this paper
• Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon?

  2019cites this paper
• Myocardial Oxidative Stress and Metabolic Diseases

  2019cites this paper
• Key Cellular Effectors in ROS-Mediated Cardiac Diseases

  2019cites this paper
• mTOR and Aging: An Old Fashioned Dress

  2019cites this paper
• Short-term rapamycin persistently improves cardiac function after cessation of treatment in aged male and female mice.

  2018influential citation
• A brain‐specific isoform of apoptosis‐inducing factor 2 attenuates ischemia‐induced oxidative stress in HT22 cells

  2018cites this paper
• Mitochondrial oxidative stress and cardiac ageing

  2018cites this paper
• Mitochondrial oxidative stress and cardiac ageing.

  2018cites this paper
• Anti‑aging effects of melatonin on the myocardial mitochondria of rats and associated mechanisms.

  2017cites this paper
• Antioxidant and Anti-aging Activities of Silybum Marianum Protein Hydrolysate in Mice Treated with D-galactose.

  2017cites this paper
• Mitochondrial function in hypoxic ischemic injury and influence of aging

  2017cites this paper
• Effects of Sedentary Aging and Lifelong Exercise on Left Ventricular Systolic Function

  2017cites this paper
• The role of mitochondria in the myocardium of senescent Meriones unguiculates

  2017cites this paper
• Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin

  2017cites this paper
• Mitochondria and oxidative stress in heart aging

  2016cites this paper
• Effects of exercise on markers of oxidative stress: an Ancillary analysis of the Alberta Physical Activity and Breast Cancer Prevention Trial

  2016cites this paper
• Reviews of Physiology, Biochemistry and Pharmacology, Vol. 172

  2016cites this paper
• The evaluate and compare the effects of the Tacrolimus and Sirolimus on the intestinal system using an intestinal cell culture model

  2016cites this paper
• The Stress-Response MAP Kinase Signaling in Cardiac Arrhythmias.

  2016cites this paper
• Generation of reactive oxygen species and their impact on the health related parameters: A critical review

  2016cites this paper
• Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivo.

  2015cites this paper
• MnSOD overexpression reduces fibrosis and pro-apoptotic signaling in the aging mouse heart.

  2015cites this paper
• The role of sirtuins in cardiac disease.

  2015cites this paper
• Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies

  2015cites this paper
• Mitochondrial dysfunction in cardiac aging.

  2015cites this paper
• Protective role of melatonin in mitochondrial dysfunction and related disorders

  2015influential citation
• Cardiac Mitochondrial Adaptations Induced by Elevated Lipid Exposure

  2015cites this paper
• Metabolic syndrome, aging and involvement of oxidative stress.

  2015cites this paper
• Manganese superoxide dismutase and oxidative stress modulation.

  2015cites this paper
• Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review.

  2015cites this paper
• Age-Dependent Changes of Redox Ratio in Rat Brain Parts, Internal Organs and Blood Plasma

  2015cites this paper
• SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillation

  2015cites this paper
• A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.

  2014cites this paper
• Cardiac High-Energy Phosphate Metabolism Alters with Age as Studied in 196 Healthy Males with the Help of 31-Phosphorus 2-Dimensional Chemical Shift Imaging

  2014cites this paper
• Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats.

  2014cites this paper
• Aging and injury: alterations in cellular energetics and organ function.

  2014cites this paper
• Bioenergetics and mitochondrial dysfunction in aging: recent insights for a therapeutical approach.

  2014cites this paper
• New Insights into the Chemical and Biochemical Basis of the “Yang-Invigorating” Action of Chinese Yang-Tonic Herbs

  2014cites this paper
• Cardiomyocyte maturation: It takes a village to raise a kid.

  2014cites this paper
• Silybum marianum oil attenuates oxidative stress and ameliorates mitochondrial dysfunction in mice treated with D-galactose

  2014cites this paper
• Molecular identification for epigallocatechin-3-gallate-mediated antioxidant intervention on the H2O2-induced oxidative stress in H9c2 rat cardiomyoblasts

  2014cites this paper
• First‐in‐class cardiolipin‐protective compound as a therapeutic agent to restore mitochondrial bioenergetics

  2014influential citation
• Molecular identification for epigallocatechin-3- gallate-mediated antioxidant intervention on the H 2 O 2 -induced oxidative stress in H9c2 rat

  2014cites this paper
• The Influence of Erythropoietin (EPO T→G) and α-Actinin-3 (ACTN3 R577X) Polymorphisms on Runners' Responses to the Dietary Ingestion of Antioxidant Supplementation Based on Pequi Oil (Caryocar brasiliense Camb.): A Before-After Study

  2014cites this paper
• Role of Impaired Mitochondrial Autophagy in Cardiac Aging: Mechanisms and Therapeutic Implications

  2014cites this paper
• The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.

  2014cites this paper
• SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3–FOXO1 signaling pathway

  2013cites this paper
• Mitochondria in Cardiovascular Physiology and Disease Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease : from mechanisms to therapeutics

  2013cites this paper
• Ursolic-Acid-Enriched Herba Cynomorii Extract Protects against Oxidant Injury in H9c2 Cells and Rat Myocardium by Increasing Mitochondrial ATP Generation Capacity and Enhancing Cellular Glutathione Redox Cycling, Possibly through Mitochondrial Uncoupling

  2013cites this paper
• Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

  2013cites this paper
• Impact of Aging on Steroid Hormone Biosynthesis and Secretion

  2013cites this paper
• Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins

  2013cites this paper
• Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target?

  2013cites this paper
• Acute effect of brisk walking with graduated compression stockings on vascular endothelial function and oxidative stress

  2013cites this paper
• AGE FEATURES OF MORFOFUNCTIONAL CHANGES IN NORMAL CARDIAC MUSCLE AND UNDER THE INFLUENCE OF DAMAGING FACTORS (LITERATURE REVIEW)

  2013cites this paper
• Effects of Voluntary Physical Activity and Endurance Training on Cardiac Mitochondrial Function of Rats Sub-Chronically Treated with Doxorubicin

  2013cites this paper
• Aging, Nutrition and Lifestyle

  2013cites this paper
• From Oocytes and Pluripotent Stem Cells to Fully Differentiated Fates: (Also) a Mitochondrial Odyssey

  2013cites this paper
• Effects of Voluntary Physical Activity and Endurance Training on Cardiac Mitochondrial Function of Rats Sub-Chronically Treated with Doxorubicin

  2013cites this paper
• UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FISIOLÓGICAS

  2013cites this paper
• Mitochondrial plasticity in pathophysiological conditions

  2013cites this paper
• SÍNDROME METABÓLICO, DIABETES Y ESTRÉS OXIDATIVO EN LA ENFERMEDAD DE ALZHEIMER Y PARKINSON. PAPEL POTENCIAL DEL PIROFOSFATO DE TIAMINA

  2013cites this paper
• Aging biology: a new frontier for drug discovery

  2012cites this paper
• How cardiomyocytes make the heart old.

  2012cites this paper
• Cardiac Ageing and Systemic Disorders

  2012cites this paper
• Oxidative Damage to Proteins and Lipids During Ageing

  2012cites this paper
• Autophagy and cardiovascular aging

  2012cites this paper
• Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.

  2012cites this paper
• Lead-induced cardiac and hematological alterations in aging Wistar male rats: alleviating effects of nutrient metal mixture

  2012influential citation
• Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging: Mechanisms and Therapeutic Opportunities

  2012cites this paper
• Cardiac Subsarcolemmal and Interfibrillar Mitochondria Display Distinct Responsiveness to Protection by Diazoxide

  2012cites this paper
• Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels

  2012cites this paper
• Rat Cardiac Mitochondrial Sub-populations Show Distinct Features of Oxidative Phosphorylation during Ischemia, Reperfusion and Ischemic Preconditioning

  2012cites this paper
• Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?

  2012cites this paper
• , Roberto Bernabei , Christiaan Leeuwenburgh and Emanuele Therapeutic Opportunities Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging : Mechanisms and

  2012cites this paper
• subepicardium mitochondrial dysfunction begins in the streptozotocin-induced diabetes mellitus: evidence that the rat left ventricle in health, aging, and Transmural differences in respiratory capacity across

  2011cites this paper
• Metabolismo mitocondrial, radicais livres e envelhecimento

  2011cites this paper
• Physical Exercise Regulates p53 Activity Targeting SCO2 and Increases Mitochondrial COX Biogenesis in Cardiac Muscle with Age

  2011cites this paper