Peroxidation of linoleic, arachidonic and oleic acid in relation to the induction of oxidative DNA damage and cytogenetic effects.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Carcinogenesis

• Publication date

  1994-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1093/CARCIN/15.7.1399PMID 8033317
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response.

  1992cited by this paper
• Electron spin resonance spectroscopy of oxygen radicals generated by synthetic fecapentaene-12 and reduction of fecapentaene mutagenicity to Salmonella typhimurium by hydroxyl radical scavenging.

  1992cited by this paper
• Generation of hydroxyl radical from linoleic acid hydroperoxide in the presence of epinephrine and iron.

  1992cited by this paper
• Determination of malonaldehyde-modified 2'-deoxyguanosine-3'-monophosphate and DNA by 32P-postlabelling.

  1992cited by this paper
• Superoxide and peroxyl radical generation from the reduction of polyunsaturated fatty acid hydroperoxides by soybean lipoxygenase.

  1991cited by this paper
• Linoleic acid hydroperoxide concentration in relation to mutagenicity of repeatedly used deep-frying fats

  1989cited by this paper
• Hydroxy- and hydroperoxy-6,8,11,14-eicosatetraenoic acids induce DNA strand breaks in human lymphocytes.

  1989cited by this paper
• Singlet oxygen production by biological systems.

  1989cited by this paper
• The search for the causes of breast and colon cancer

  1989cited by this paper
• Assessment of mutagenic activity of repeatedly used deep-frying fats.

  1988cited by this paper
• Interaction of lipid peroxidation products with DNA. A review.

  1988cited by this paper
• Mutagenicity of 4-hydroxynonenal in V79 Chinese hamster cells.

  1987cited by this paper
• Fat and colon cancer: how firm is the epidemiologic evidence?

  1987cited by this paper
• Diet in the etiology of breast cancer.

  1987cited by this paper
• Carbon-centered free radical intermediates in the hematin- and ram seminal vesicle-catalyzed decomposition of fatty acid hydroperoxides.

  1986cited by this paper
• Radiation damage to phi X174 DNA and biological effects.

  1986cited by this paper
• Cytotoxicity, DNA fragmentation and sister-chromatid exchange in Chinese hamster ovary cells exposed to the lipid peroxidation product 4-hydroxynonenal and homologous aldehydes.

  1986cited by this paper
• Conversion of linoleic acid hydroperoxide to hydroxy, keto, epoxyhydroxy, and trihydroxy fatty acids by hematin.

  1985cited by this paper
• Requirement of essential fatty acid for mammary tumorigenesis in the rat.

  1985cited by this paper
• Effects of adduct formation on the biological activity of single- and double-stranded øX174 DNA, modified by N-acetoxy-N-acetyl-2-aminofluorene.

  1984cited by this paper
• Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo.

  1984cited by this paper
• Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases.

  1983cited by this paper
• Effect of the prostaglandin synthetase inhibitor indomethacin on 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats fed different levels of fat.

  1983cited by this paper
• Mechanisms by which dietary fat may stimulate mammary carcinogenesis in experimental animals.

  1981cited by this paper
• Spin trapping of superoxide and hydroxyl radical: practical aspects.

  1980cited by this paper
• Effect of malonaldehyde and acetaldehyde on cultured mammalian cells: Growth, morphology, and synthesis of macromolecules.

  1980cited by this paper
• Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices

  1975cited by this paper
• Effect of dietary beef fat on intestinal tumor formation by azoxymethane in rats.

  1975cited by this paper
• New Giemsa method for the differential staining of sister chromatids

  1974cited by this paper
• The radiosensitivity of bacteriophage DNA in aqueous solution.

  1967cited by this paper

• Optimizing the Comet Assay-Based In Vitro DNA Repair Assay for Placental Tissue: A Pilot Study with Pre-Eclamptic Patients

  2023cites this paper
• Antioxidant Activity of Hemp (Cannabis sativa L.) Seed Oil in Drosophila melanogaster Larvae under Non-Stress and H2O2-Induced Oxidative Stress Conditions

  2021cites this paper
• Antioxidant Activity of Hemp ( Cannabis sativa L.) Seed Oil in Drosophila melanogaster Larvae under Non-Stress and H 2 O 2 Induced Oxidative Stress Conditions potential including antioxidant, antitumor, anti-Citation:

  2021cites this paper
• Artificial Intelligence uncovers carcinogenic human metabolites

  2021cites this paper
• Photocatalytic and photoluminescent properties of a system based on SmPO4 nanostructure phase

  2020cites this paper
• Evaluation of cytotoxicity and genotoxicity induced by oleic acid‐coated iron oxide nanoparticles in human astrocytes

  2019cites this paper
• Betulinic acid induces DNA damage and apoptosis in SiHa cells.

  2018cites this paper
• L-carnitine mitigates UVA-induced skin tissue injury in rats through downregulation of oxidative stress, p38/c-Fos signaling, and the proinflammatory cytokines.

  2018cites this paper
• Actividad citotóxica y genotóxica de ácidos grasos omega en células de cáncer de próstata PC-3

  2018cites this paper
• Lipid Peroxidation, Diet, and the Genotoxicology of Aging

  2016cites this paper
• Phytochemical profiles, antioxidant activities of functional herb Abrus cantoniensis and Abrus mollis.

  2015cites this paper
• Antigenotoxic and antioxidant effects of the Mongolian medicinal plant Leptopyrum fumarioides (L): an in vitro study.

  2014cites this paper
• Lethal and sub-lethal effects of UV-B radiation exposure on the collembolan Folsomia candida (Willem) in the laboratory

  2013cites this paper
• ethal and sublethal effects of UV-B radiation exposure on the collembolan olsomia candida ( Willem ) in the laboratory uy

  2013cites this paper
• Induction of Apoptosis in Human Breast Cancer Cells via Caspase Pathway by Vernodalin Isolated from Centratherum anthelminticum (L.) Seeds

  2013cites this paper
• Genotoxic effects of neutrophils and hypochlorous acid.

  2010cites this paper
• n-3 LC-PUFA-enriched dairy products are able to reduce cardiovascular risk factors: a double-blind, cross-over study.

  2010cites this paper
• Flavouring Group Evaluation 62 Rev1 (FGE.62 Rev1): Consideration of of linear and branched-chain aliphatic unsaturated, unconjugated alcohols, aldehydes, acids, and related esters evaluated by JECFA (61st and 68th meeting) structurally related to branched: Flavouring Group Evaluation 62, Revision 1

  2010cites this paper
• Adult-onset, short-term dietary restriction reduces cell senescence in mice

  2010cites this paper
• Polyunsaturated Fatty Acids, DNA Repair Single Nucleotide Polymorphisms and Colorectal Cancer in the Singapore Chinese Health Study

  2010cites this paper
• Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation.

  2010cites this paper
• The effect of oxidative stress on nucleotide-excision repair in colon tissue of newborn piglets.

  2010cites this paper
• How DNA lesions are turned into powerful killing structures: insights from UV-induced apoptosis.

  2009cites this paper
• Die TRAIL-Suszeptibilität humaner Melanomzellen : Bedeutung des Tumorprogressionsstadiums und Modulation durch Immunsuppressiva

  2009cites this paper
• Proton pump inhibitor therapy in gastro‐oesophageal reflux disease decreases the oesophageal immune response but does not reduce the formation of DNA adducts

  2008cites this paper
• Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission

  2008cites this paper
• Witch hazel (Hamamelis virginiana) fractions and the importance of gallate moieties--electron transfer capacities in their antitumoral properties.

  2008cites this paper
• Positive Association Between DNA Strand Breaks in Peripheral Blood Mononuclear Cells and Polyunsaturated Fatty Acids in Red Blood Cells From Women

  2007cites this paper
• Hydrogen peroxide is a mediator of indole‐3‐acetic acid/horseradish peroxidase‐induced apoptosis

  2006cites this paper
• Light-activated indole-3-acetic acid induces apoptosis in g361 human melanoma cells.

  2006cites this paper
• Antioxidant enzymes and lipid peroxidation in sturgeon Acipenser naccarii and trout Oncorhynchus mykiss. A comparative study

  2006cites this paper
• XRCC1 and XRCC3 Polymorphisms and Their Role as Effect Modifiers of Unsaturated Fatty Acids and Antioxidant Intake on Colorectal Adenomas Risk

  2005cites this paper
• The effect of free fatty acids on endothelial cells

  2005cites this paper
• Apoptosis in Human Skin: Role in Pathogenesis of Various Diseases and Relevance for Therapy

  2005cites this paper
• Genotoxicity and physicochemical characteristics of traffic‐related ambient particulate matter

  2005cites this paper
• Proton-Induced X-ray Emission (PIXE) Analysis and DNA-chain Break study in rat hepatocarcinogenesis: A possible chemopreventive role by combined supplementation of vanadium and beta-carotene

  2005cites this paper
• Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain.

  2004cites this paper
• In Vitro and In Vivo Studies on Oxygen Free Radical and DNA Adduct Formation in Rat Lung and Liver during Benzo[a]pyrene Metabolism

  2004cites this paper
• Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells.

  2004cites this paper
• Effect of dietary n-3 and n-6 fatty acids on tobramycin induced nephrotoxicity.

  2004cites this paper
• In vitro investigations into the interaction of beta-carotene with DNA: evidence for the role of carbon-centered free radicals.

  2004cites this paper
• Protective effect of supplementation of fish oil with high n-3 polyunsaturated fatty acids against oxidative stress-induced DNA damage of rat liver in vivo.

  2003cites this paper
• Effect of supplementation of n-3 polyunsaturated fatty acids on oxidative stress-induced DNA damage of rat hepatocytes.

  2003cites this paper
• Suppression of free radical-induced DNA strand breaks by linoleic acid and low density lipoprotein in vitro.

  2003cites this paper
• Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid.

  2003cites this paper
• Effect of corn oil and vitamin E on the oxidative status of adipose tissues and liver in rat

  2003cites this paper
• Independent contribution of three different pathways to ultraviolet-B-induced apoptosis.

  2002cites this paper
• DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way

  2002cites this paper
• Biologic damage resulting from exposure to tobacco smoke and from radon: implication for preventive interventions

  2002cites this paper
• Oleic acid

  2002cites this paper
• Mechanisms of UV‐Induced Signal Transduction

  2002cites this paper
• Effect of Supplementation of a Reductone in Coffee, Hydroxyhydroquinone, on Lipid Peroxidation and DNA Damage of Rat Organs

  2002cites this paper
• Aqueous infusions of mediterranean herbs exhibit antioxidant activity towards iron promoted oxidation of phospholipids, linoleic acid, and deoxyribose

  2001cites this paper
• Cooking oil fume-induced cytokine expression and oxidative stress in human lung epithelial cells.

  2001cites this paper
• Biomonitoring on carcinogenic metals and oxidative DNA damage in a cross-sectional study.

  2001cites this paper
• 8‐HYDROXY‐2′DEOXYGUANOSINE LEVELS AND ANTIOXIDANT STATUS IN RAT LIVER FED WITH OLIVE AND CORN OIL DIETS: EFFECT OF ASCORBIC ACID SUPPLEMENATION

  2001cites this paper
• Therapeutic potential of dietary phase 2 enzyme inducers in ameliorating diseases that have an underlying inflammatory component.

  2001cites this paper
• Plasma xanthophyll carotenoids correlate inversely with indices of oxidative DNA damage and lipid peroxidation.

  2000cites this paper
• Effects of dietary fats (fish, olive and high-oleic-acid sunflower oils) on lipid composition and antioxidant enzymes in rat liver

  1999cites this paper
• Increased fruit and vegetable consumption reduces indices of oxidative DNA damage in lymphocytes and urine.

  1999cites this paper
• Dietary fat and prostate cancer: current status.

  1999cites this paper
• Mutations at G:C base pairs predominate after replication of peroxyl radical-damaged pSP189 plasmids in human cells.

  1999cites this paper
• Effects of oleic acid, docosahexaenoic acid and eicosapentaenoic acid on background and genotoxin-induced frequencies of SCEs in Indian muntjac fibroblasts.

  1999cites this paper
• REVIEW Dietary Fat and Prostate Cancer: Current Status

  1999cites this paper
• Serum concentrations of carotenoids, alpha-tocopherol, fatty acids, and lipid peroxides among Japanese in Japan, and Japanese and Caucasians in the US.

  1999cites this paper
• High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2-deoxyguanosine excretion in rats.

  1998cites this paper
• Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts.

  1998cites this paper
• The influence of DNA glycosylases on spontaneous mutation.

  1998cites this paper
• Elevated reversible and irreversible lipid peroxidation in human oesophageal cancer.

  1998cites this paper
• Normoxic ventilation after cardiac arrest reduces oxidation of brain lipids and improves neurological outcome.

  1998cites this paper
• Experimental study of oxidative DNA damage.

  1998cites this paper
• Reducing effects of garlic constituents on DNA adduct formation in human lymphocytes in vitro.

  1997cites this paper
• Extracellular factor(s) following exposure to alpha particles can cause sister chromatid exchanges in normal human cells.

  1997cites this paper
• Oxidative damage to DNA: do we have a reliable biomarker?

  1996cites this paper
• Iron intake and the risk of colorectal cancer.

  1996cites this paper
• Iron Intake and the Risk of Colorectal

  1996cites this paper
• Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase.

  1995cites this paper
• Lack of Promoting Effects of α‐Linolenic, Linoleic or Palmitic Acid on Urinary Bladder Carcinogenesis in Rats

  1995cites this paper