Clinical Phenotype of Families with Longevity

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of The American Geriatrics Society

• Publication date

  2004-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1532-5415.2004.52068.xPMID 14728640
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Submitting articles to the BMJ

  2002cited by this paper
• Life-long sustained mortality advantage of siblings of centenarians

  2002cited by this paper
• Offspring of Centenarians Have a Favorable Lipid Profile

  2001cited by this paper
• A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4

  2001cited by this paper
• Searching for human longevity genes: the future history of gerontology in the post-genomic era.

  2001cited by this paper
• Inheritance of human longevity in Iceland

  2000cited by this paper
• Body-mass index and mortality in a prospective cohort of U.S. adults.

  1999cited by this paper
• Siblings of centenarians live longer.

  1998cited by this paper

• Transcriptional Control of Hepatocellular Carcinoma Cells Aggressiveness by AAV2/8-Mediated Delivery of Human Centenarian-Associated SIRT6 N308K/A313S

  2026cites this paper
• Factors involved in human healthy aging: insights from longevity individuals

  2025cites this paper
• Increased Genetic Protection Against Alzheimer’s Disease in Centenarians

  2025cites this paper
• Gray Matter Covariance Networks Associated with Parental Longevity - Results from the LonGenity Study.

  2025cites this paper
• Increased genetic protection against Alzheimer's disease in centenarians.

  2025cites this paper
• Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity

  2025cites this paper
• Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

  2024cites this paper
• Phenotypic upregulation of hexocylceramides and ether‐linked phosphocholines as markers of human extreme longevity

  2024cites this paper
• Genome integrity as a potential index of longevity in Ashkenazi Centenarian’s families

  2024cites this paper
• Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4‐induced brain pathology

  2024cites this paper
• Linking Aging to Cancer: The Role of Chromatin Biology.

  2024cites this paper
• Effect of Familial Longevity on Frailty and Sarcopenia: A Case–Control Study

  2023cites this paper
• Biomarkers of aging

  2023cites this paper
• The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity

  2023cites this paper
• Discovering Biological Mechanisms of Exceptional Human Health Span and Life Span.

  2023cites this paper
• Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop

  2022cites this paper
• Aging, Equality and the Human Healthspan

  2022cites this paper
• Single‐Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring

  2022cites this paper
• Metabolic reprogramming: a bridge between aging and tumorigenesis

  2022cites this paper
• Integrity of hypothalamic–pituitary‐testicular axis in exceptional longevity

  2022cites this paper
• Human centenarian–associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids

  2022cites this paper
• Low Risk for Developing Diabetes Among the Offspring of Individuals With Exceptional Longevity and Their Spouses

  2022cites this paper
• The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging

  2022cites this paper
• Centenarians

  2022cites this paper
• High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity

  2022cites this paper
• Combatting chronic metabolic disorders and delaying aging by improving glucose-insulin metabolism and fat accumulation in nondiabetics

  2022cites this paper
• BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring

  2022cites this paper
• Omics in a Digital World: The Role of Bioinformatics in Providing New Insights Into Human Aging

  2021cites this paper
• Interconnections between Inflammageing and Immunosenescence during Ageing

  2021cites this paper
• New Directions in Research on Aging

  2021cites this paper
• Cancer and Alzheimer’s disease inverse relationship: an age-associated diverging derailment of shared pathways

  2020cites this paper
• The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan

  2020cites this paper
• The impact of ageing on lipid-mediated regulation of adult stem cell behavior and tissue homeostasis.

  2020cites this paper
• Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes or CIAO)

  2020cites this paper
• Exome-wide association studies in general and long-lived populations identify genetic variants related to human age

  2020cites this paper
• Genetics of frailty: a longevity perspective.

  2020cites this paper
• A bibliometric study of research pertaining to the oldest-old (age eighty-five and older)

  2020cites this paper
• Investigating the Vulnerability of Motorcyclists to Crashes and Injury

  2020cites this paper
• PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects

  2019cites this paper
• Intergenerational transmission of longevity is not affected by other familial factors: Evidence from 16,905 Dutch families from Zeeland, 1812-1962

  2019cites this paper
• Circulating miRNAs in Successful and Unsuccessful Aging. A mini-review.

  2019cites this paper
• Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities.

  2019cites this paper
• Genetic Markers of Extreme Human Longevity

  2019cites this paper
• Centenarian Offspring as a Model of Successful Ageing

  2019cites this paper
• Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians

  2018cites this paper
• The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description

  2018cites this paper
• The Super-Seniors Study: Phenotypic characterization of a healthy 85+ population

  2018cites this paper
• A heterogeneity based case-control analysis of motorcyclist's injury crashes: Evidence from motorcycle crash causation study.

  2018influential citation
• Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring

  2018cites this paper
• Vascular dysfunction and insulin resistance in aging.

  2018cites this paper
• Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies

  2018influential citation
• Healthy at 100: Genetic factors and phenotypes associated with healthy aging and longevity

  2018cites this paper
• GH/IGF-I/insulin system in centenarians.

  2017cites this paper
• Four Genome-Wide Association Studies Identify New Extreme Longevity Variants

  2017influential citation
• Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients

  2017cites this paper
• Association of Family History of Exceptional Longevity With Decline in Physical Function in Aging

  2017cites this paper
• Gut microbiota changes in the extreme decades of human life: a focus on centenarians

  2017cites this paper
• The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature

  2017cites this paper
• Association between Sleep Patterns and Health in Families with Exceptional Longevity

  2017cites this paper
• Effect of Exceptional Parental Longevity and Lifestyle Factors on Prevalence of Cardiovascular Disease in Offspring.

  2017cites this paper
• BOLOGICAL MARKERS FOR LONGEVITY AND DISEASES AND USES THEREOF

  2017cites this paper
• Gut microbiota changes in the extreme decades of human life : a

  2017cites this paper
• FOXO Transcriptional Factors and Long-Term Living

  2017cites this paper
• IMPACT OF EARLY PERSONAL HISTORY CHARACTERISTICS ON THE PACE OF AGING

  2017cites this paper
• Impact of early personal‐history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan

  2017cites this paper
• The role of dietary patterns and exceptional parental longevity in healthy aging

  2017cites this paper
• Life at Age 100: An International Research Agenda for Centenarian Studies

  2016influential citation
• Centenarians’ offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview

  2016cites this paper
• Contributions of Telomere Biology to Human Age-Related Disease

  2016cites this paper
• Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional Longevity without compromise to muscle mass and function

  2016cites this paper
• Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for PAPSS2 as a Longevity Gene.

  2016cites this paper
• TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study

  2016cites this paper
• Cholesteryl ester transfer protein (CETP) I405V polymorphism and cardiovascular disease in eastern European Caucasians – a cross-sectional study

  2016cites this paper
• Microbial translocation and skeletal muscle in young and old vervet monkeys

  2016cites this paper
• Deciphering hallmark processes of aging from interaction networks.

  2016cites this paper
• Effects of heated hydrotherapy on muscle HSP70 and glucose metabolism in old and young vervet monkeys

  2016cites this paper
• Reduced intestinal motility, mucosal barrier function, and inflammation in aged monkeys

  2016cites this paper
• Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

  2015cites this paper
• Muscle heat shock protein 70 predicts insulin resistance with aging.

  2015cites this paper
• Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

  2015cites this paper
• The influence of gender on inheritance of exceptional longevity

  2015cites this paper
• Burden of Common Complex Disease Variants in the Exomes of Two Healthy Centenarian Brothers

  2015cites this paper
• Germ line and Somatic Characteristics of the Long-Lived Genome

  2015cites this paper
• A novel life span regulating locus at chr13q34 influencing serum triiodothyronine level

  2015cites this paper
• Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span.

  2015cites this paper
• Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged Mice.

  2015cites this paper
• Evolutionary genetic bases of longevity and senescence.

  2015cites this paper
• Parkinson's disease as a result of aging

  2015cites this paper
• Management of Dyslipidemia in the Elderly

  2014cites this paper
• Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

  2014cites this paper
• Renal function in familial longevity: the Leiden Longevity Study.

  2014cites this paper
• Sex Differential Effect of Parental Longevity on the Risk of Dementia

  2014cites this paper
• Association of exceptional parental longevity and physical function in aging

  2014cites this paper
• Individuals with Exceptional Longevity Manifest a Delayed Association Between Vitamin D Insufficiency and Cognitive Impairment

  2014cites this paper
• Episodic memory and executive function in familial longevity

  2014influential citation
• Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.

  2014cites this paper
• Innovating Aging: Promises and Pitfalls on the Road to Life Extension

  2014cites this paper
• Genes for Exceptional Longevity

  2014cites this paper
• Genetic and biomarker studies of human longevity

  2014influential citation
• Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population.

  2014cites this paper