PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Cancer Research

• Publication date

  2000-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10706094
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Prostate Expression Database

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Identification of the deoxyribonucleic acid-binding site of a regulatory protein involved in prostate-specific and androgen receptor-dependent gene expression.

  1999cited by this paper
• PEDB: the Prostate Expression Database

  1999cited by this paper
• Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

  1999cited by this paper
• New features of the Blocks Database servers

  1999cited by this paper
• Structural alterations of chromosome 5 in twelve human prostate cancer cell lines.

  1998cited by this paper
• An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones.

  1998cited by this paper
• Isolation and androgen regulation of the human homeobox cDNA, NKX3.1

  1998cited by this paper
• Human Kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate.

  1998cited by this paper
• A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer.

  1997cited by this paper
• Genes regulated by androgen in the rat ventral prostate.

  1997cited by this paper
• Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3.

  1997cited by this paper
• Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes

  1997cited by this paper
• Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.

  1997cited by this paper
• Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.

  1997cited by this paper
• Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: A stem cell model

  1996cited by this paper
• Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping.

  1996cited by this paper
• Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer

  1996influential reference
• Chromosome 5 suppresses tumorigenicity of PC3 prostate cancer cells: correlation with re-expression of alpha-catenin and restoration of E-cadherin function.

  1995cited by this paper
• Detection and characterization of the prostate‐specific membrane antigen (PSMA) in tissue extracts and body fluids

  1995cited by this paper
• Isolation of active recombinant XPG protein, a human DNA repair endonuclease.

  1994cited by this paper
• NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes.

  1994cited by this paper
• Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.

  1993influential reference
• Androgen induction of a human prostate-specific kallikrein, hKLK2: characterization of an androgen response element in the 5' promoter region of the gene.

  1993cited by this paper
• Differential 3' polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression.

  1993cited by this paper
• Fluorescence in situ hybridization.

  1993cited by this paper
• The promoter of the prostate-specific antigen gene contains a functional androgen responsive element.

  1991cited by this paper
• Molecular cloning : a laboratory manual. Cold Spring Harbor, NY

  1989cited by this paper
• Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal.

  1989influential reference
• Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids

  1988cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
• The endocrinology and treatment of prostate tumor progression.

  1987cited by this paper
• Genetic instability coupled to clonal selection as a mechanism for tumor progression in the Dunning R-3327 rat prostatic adenocarcinoma system.

  1982cited by this paper

• Mass spectrometry-based proteomics in glioblastoma - current understanding and future impact.

  2025cites this paper
• Origin of functional de novo genes in humans from “hopeful monsters”

  2024cites this paper
• LncRNA PART1 promotes malignant biological behaviours associated with head and neck cancer cells via synergistic action with FUT6

  2024cites this paper
• Long non-coding RNAs in cancer: multifaceted roles and potential targets for immunotherapy

  2024cites this paper
• Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network in ischemic stroke.

  2024cites this paper
• Identification of androgen response‐related lncRNAs in prostate cancer

  2023cites this paper
• A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders

  2023cites this paper
• Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region

  2023cites this paper
• Reduced PDE4D7 expression in prostate cancer correlates with down-regulation of genomic elements within the up-stream PDE4D coding region on chromosome 5

  2022cites this paper
• LncRNA PART1 inhibits glioma proliferation and migration via miR-374b/SALL1 axis.

  2022cites this paper
• Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer.

  2022cites this paper
• PART1 destabilized by NOVA2 regulates blood-brain barrier permeability in endothelial cells via STAU1-mediated mRNA degradation.

  2022cites this paper
• A Review of Special Considerations on Insulin Resistance Induced Hyperandrogenemia in Women with Polycystic Ovary Syndrome: A Prominent COVID-19 Risk Factor

  2022cites this paper
• In silico characterization of competing endogenous RNA network in castration-resistant prostate cancer cells in presence of the natural compound atraric acid using RNA-seq analysis.

  2022cites this paper
• Long non‑coding RNA PART1: dual role in cancer

  2022influential citation
• The Role of Tumor-related LncRNA PART1 in cancer.

  2021cites this paper
• LncRNA prostate androgen-regulated transcript 1 (PART 1) functions as an oncogene in osteosarcoma via sponging miR-20b-5p to upregulate BAMBI

  2021cites this paper
• lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR-18a-5p/SOX6 signaling axis

  2021cites this paper
• Феномен эволюционного “самозарождения” генов

  2021cites this paper
• Excavating novel diagnostic and prognostic long non-coding RNAs (lncRNAs) for head and neck squamous cell carcinoma: an integrated bioinformatics analysis of competing endogenous RNAs (ceRNAs) and gene co-expression networks

  2021cites this paper
• LncRNA PART1 promotes cell proliferation and inhibits apoptosis of oral squamous cell carcinoma by blocking EZH2 degradation.

  2021cites this paper
• Long non-coding RNA PART1 predicts a poor prognosis and promotes the malignant progression of pancreatic cancer by sponging miR-122

  2021cites this paper
• The Phenomenon of Evolutionary “De Novo Generation” of Genes

  2021cites this paper
• LncRNA PART1 Promotes Proliferation and Migration, Is Associated with Cancer Stem Cells, and Alters the miRNA Landscape in Triple-Negative Breast Cancer

  2021cites this paper
• LncRNA PART1 Exerts Tumor-Suppressive Functions in Tongue Squamous Cell Carcinoma via miR-503-5p

  2020cites this paper
• Long noncoding RNA PART1 restrains aggressive gastric cancer through the epigenetic silencing of PDGFB via the PLZF-mediated recruitment of EZH2

  2020cites this paper
• Inhibition of lncRNA PART1 Chemosensitizes Wild Type but Not KRAS Mutant NSCLC Cells

  2020cites this paper
• LncRNA PART1 Exerts Tumor-Suppressive Functions in Tongue Squamous Cell Carcinoma via miR-503-5p

  2020cites this paper
• LncRNA PART1 facilitates the malignant progression of colorectal cancer via miR‐150‐5p/LRG1 axis

  2020cites this paper
• CMAR_A_245257 4453..4460

  2020cites this paper
• LncRNA PART1 Exerts Tumor-Suppressive Functions in Tongue Squamous Cell Carcinoma via miR-503-5p

  2020cites this paper
• OTT_A_259962 9203..9211

  2020cites this paper
• Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway

  2020cites this paper
• Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway

  2020cites this paper
• CMAR_A_246311 3771..3782

  2020cites this paper
• Long Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis

  2020cites this paper
• Exosomal prostate-specific G-protein-coupled receptor induces osteoblast activity to promote the osteoblastic metastasis of prostate cancer

  2020cites this paper
• Exosome carrying PSGR promotes stemness and epithelial-mesenchymal transition of low aggressive prostate cancer cells.

  2020cites this paper
• Long Noncoding RNA PART1 Promotes Hepatocellular Carcinoma Progression via Targeting miR-590-3p/HMGB2 Axis

  2020cites this paper
• LncRNA PART‐1 targets TGFBR2/Smad3 to regulate cell viability and apoptosis of chondrocytes via acting as miR‐590‐3p sponge in osteoarthritis

  2019cites this paper
• Long noncoding RNA PART1 promotes progression of non‐small cell lung cancer cells via JAK‐STAT signaling pathway

  2019cites this paper
• LncRNA and mRNA integration network reconstruction reveals novel key regulators in esophageal squamous-cell carcinoma.

  2019cites this paper
• De novo gene birth

  2019cites this paper
• Downregulated Long Noncoding RNA PART1 Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer

  2019cites this paper
• Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA

  2018cites this paper
• Complex integrated analysis of lncRNAs-miRNAs-mRNAs in oral squamous cell carcinoma.

  2017cites this paper
• LncRNA PART1 modulates toll-like receptor pathways to influence cell proliferation and apoptosis in prostate cancer cells

  2017cites this paper
• PART1 expression is associated with poor prognosis and tumor recurrence in stage I-III non-small cell lung cancer

  2017cites this paper
• PART-1 functions as a competitive endogenous RNA for promoting tumor progression by sponging miR-143 in colorectal cancer.

  2017cites this paper
• Open questions in the study of de novo genes: what, how and why

  2016cites this paper
• Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases

  2016influential citation
• Conservation and Losses of Non-Coding RNAs in Avian Genomes

  2015cites this paper
• Identification and Validation of Long Noncoding RNA Biomarkers in Human Non–Small-Cell Lung Carcinomas

  2015cites this paper
• The cAMP phosphodiesterase-4 D 7 ( PDE 4 D 7 ) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells

  2014influential citation
• Conservation and losses of avian non-coding RNA loci

  2014cites this paper
• Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer

  2014cites this paper
• The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells

  2014influential citation
• Functional characterisation of phosphodiesterase 4D7 in prostate cancer

  2014cites this paper
• Fine-Mapping of 5q12.1–13.3 Unveils New Genetic Contributors to Caries

  2013cites this paper
• A long non-coding RNA signature in glioblastoma multiforme predicts survival.

  2013cites this paper
• Transcriptome-Wide Detection of Differentially Expressed Coding and Non-Coding Transcripts and Their Clinical Significance in Prostate Cancer

  2012cites this paper
• Novel biomarkers and therapeutic targets for prostate cancer.

  2010influential citation
• Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation

  2010cites this paper
• A personal journey of discovery: developing technology and changing biology.

  2008cites this paper
• Origin of primate orphan genes: a comparative genomics approach.

  2008cites this paper
• TITLE: Superoxide dismutase and transcription factor sox9 as mediators of tumor suppression by mac25 (IGFBP-rp1) in prostate cancer cells

  2006cites this paper
• Application of Genomic Technologies to Human Prostate Cancer

  2006cites this paper
• Long-range multilocus haplotype phasing of the MHC.

  2006cites this paper
• PSGR2, a novel G‐protein coupled receptor, is overexpressed in human prostate cancer

  2006cites this paper
• Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization.

  2005cites this paper
• Gene therapy and immunotherapy of prostate cancer: Adenoviral-based strategies

  2005cites this paper
• Prostate cancer and the genomic revolution: Advances using microarray analyses.

  2005influential citation
• FSH and testosterone signaling in Sertoli cells.

  2005cites this paper
• Increased expression of prostate‐specific G‐protein‐coupled receptor in human prostate intraepithelial neoplasia and prostate cancers

  2005cites this paper
• Molecular Profiling in Prostate Cancer

  2004cites this paper
• PROSTATIC GENE EXPRESSION: PROBASIN, HUMAN PROSTATIC ACID PHOSPHATASE AND MACROPHAGE INHIBITORY CYTOKINE-1 AS MODEL GENES

  2004cites this paper
• Identification of an HLA-A*0201-restricted T-cell epitope derived from the prostate cancer-associated protein prostein

  2004cites this paper
• Future Perspectives: Immunotherapy and Vaccines in Prostate Cancer

  2004cites this paper
• Androgen receptor (AR) expression in AR‐negative prostate cancer cells results in differential effects of DHT and IGF‐I on proliferation and AR activity between localized and metastatic tumors

  2004cites this paper
• PrLZ, a Novel Prostate-Specific and Androgen-Responsive Gene of the TPD52 Family, Amplified in Chromosome 8q21.1 and Overexpressed in Human Prostate Cancer

  2004cites this paper
• Prostatic gene expression: probasin, human prostatic acid phosphatase and macrophage inhibitory cytokine-1 as model genes

  2004cites this paper
• The T Cell Receptor γ Chain Alternate Reading Frame Protein (TARP), a Prostate-specific Protein Localized in Mitochondria*

  2004cites this paper
• D‐PCa‐2: A novel transcript highly overexpressed in human prostate and prostate cancer

  2004cites this paper
• A novel human prostate-specific gene-1 (HPG-1): molecular cloning, sequencing, and its potential involvement in prostate carcinogenesis.

  2003cites this paper
• Baculoviruses as Vectors for Gene Therapy against Human Prostate Cancer

  2003cites this paper
• Genistein and daidzein downregulate prostate androgen-regulated transcript-1 (PART-1) gene expression induced by dihydrotestosterone in human prostate LNCaP cancer cells.

  2003influential citation
• Detection, Isolation and Study of Disseminated Prostate Cancer Cells in the Peripheral Blood and Bone Marrow

  2003cites this paper
• Identification of an HLA‐A*0201‐restricted T‐cell epitope derived from the prostate cancer‐associated protein trp‐p8

  2003cites this paper
• Identifying Immunotherapeutic Targets for Prostate Carcinoma through the Analysis of Gene Expression Profiles

  2002cites this paper
• Models Systems for the Study of Androgen-Regulated Gene Expression in the Central Nervous System

  2002cites this paper
• Prostate Cancer: New Horizons in Research and Treatment

  2002cites this paper
• Gene expression profiling of the human prostate androgen response program.

  2002cites this paper
• Identification of Human Male Germ Cell-associated Kinase, a Kinase Transcriptionally Activated by Androgen in Prostate Cancer Cells*

  2002cites this paper
• Comprehensive genotypic analysis of human prostate cancer cell lines and sublines derived from metastases after orthotopic implantation in nude mice.

  2002cites this paper
• University of Groningen Identification from public data of molecular markers of adenocarcinoma characteristic of the site of origin

  2002cites this paper
• Expression and regulation of prostate androgen regulated transcript-1 (PART-1) and identification of differential expression in prostatic cancer

  2001cites this paper
• Molecular cloning of a novel human gene on chromosome 4p11 by immunoscreening of an ovarian carcinoma cDNA library.

  2001cites this paper
• Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.

  2001cites this paper
• Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.

  2001cites this paper
• A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity.

  2001cites this paper