Alterations of oxidative phosphorylation complexes in astrocytomas

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Glia

• Publication date

  2014-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/glia.22621PMID 24446254
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Citrate synthase.

  2020cited by this paper
• Tp53-induced Glycolysis and Apoptosis Regulator (TIGAR) Protects Glioma Cells from Starvation-induced Cell Death by Up-regulating Respiration and Improving Cellular Redox Homeostasis*

  2012cited by this paper
• Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death

  2012cited by this paper
• Heterogeneity of mitochondrial energy metabolism in classical triphasic Wilms' tumor.

  2011cited by this paper
• The ultrastructure of lamellar stack astrocytes

  2011cited by this paper
• Learning from oncocytic tumors: Why choose inefficient mitochondria?

  2011cited by this paper
• Respiratory chain complex I is a mitochondrial tumor suppressor of oncocytic tumors.

  2011cited by this paper
• Alterations of respiratory chain complexes in sporadic pheochromocytoma.

  2011cited by this paper
• Loss of mitochondria in ganglioneuromas.

  2011cited by this paper
• Metabolic management of brain cancer.

  2011cited by this paper
• Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

  2011cited by this paper
• Neural stem cells: historical perspective and future prospects.

  2011cited by this paper
• Molecular features of thyroid oncocytic tumors.

  2010cited by this paper
• Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma

  2010cited by this paper
• Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

  2010cited by this paper
• The Warburg Effect Is Genetically Determined in Inherited Pheochromocytomas

  2009cited by this paper
• Astrocytes: biology and pathology

  2009cited by this paper
• A novel mutation of the RRM2B gene in an infant with early fatal encephalomyopathy, central hypomyelination, and tubulopathy.

  2009cited by this paper
• Lack of complex I is associated with oncocytic thyroid tumours

  2009influential reference
• Glioma stem cells: a midterm exam.

  2008cited by this paper
• Loss of Complex I due to Mitochondrial DNA Mutations in Renal Oncocytoma

  2008cited by this paper
• Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets

  2008cited by this paper
• An Assembled Complex IV Maintains the Stability and Activity of Complex I in Mammalian Mitochondria*

  2007cited by this paper
• HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity.

  2007cited by this paper
• The Prostate 68 : 11 ^ 19 ( 2008 ) Carbohydrate Restriction , ProstateCancerGrowth , andthe Insulin-LikeGrowth FactorAxis

  2007cited by this paper
• The 2007 WHO Classification of Tumours of the Central Nervous System

  2007cited by this paper
• Synaptic Islands Defined by the Territory of a Single Astrocyte

  2007cited by this paper
• The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer

  2007cited by this paper
• Brain tumors

  2007cited by this paper
• A pivotal role for p53: balancing aerobic respiration and glycolysis

  2007cited by this paper
• p53 Regulates Mitochondrial Respiration

  2006cited by this paper
• Transcription Association of VHL and SDH Mutations Link Hypoxia and Oxidoreductase Signals in Pheochromocytomas

  2006cited by this paper
• Mitochondrial mutations in cancer

  2006cited by this paper
• Metabolic patterns in malignant gliomas

  2005influential reference
• Neural stem cells and the origin of gliomas.

  2005cited by this paper
• Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma.

  2004cited by this paper
• Severe depletion of mitochondrial DNA in spinal muscular atrophy

  2003cited by this paper
• Mitochondrial DNA mutations in human colonic crypt stem cells.

  2003cited by this paper
• Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains

  2002cited by this paper
• Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.

  2002cited by this paper
• Structural and quantitative analysis of astrocytes in the mouse hippocampus.

  2002cited by this paper
• Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma.

  2001cited by this paper
• Supercomplexes in the respiratory chains of yeast and mammalian mitochondria

  2000cited by this paper
• Sporadic pheochromocytomas are rarely associated with germline mutations in the vhl tumor suppressor gene or the ret protooncogene.

  1997cited by this paper
• The p53 gene and its role in human brain tumors

  1995cited by this paper
• Histopathology, classification, and grading of gliomas

  1995cited by this paper
• Neurofibromatosis type 2 and von Hippel‐Lindau disease: From gene cloning to function

  1995influential reference
• Biochemical and molecular investigations in respiratory chain deficiencies.

  1994cited by this paper
• The ultrastructural spectrum of astrocytic neoplasms.

  1987cited by this paper
• Warburg effect revisited: merger of biochemistry and molecular biology.

  1981cited by this paper
• Tumor mitochondria and the bioenergetics of cancer cells.

  1978cited by this paper
• [1] Citrate synthase. [EC 4.1.3.7. Citrate oxaloacetate-lyase (CoA-acetylating)]

  1969cited by this paper
• Human brain tumors: an electron-microscopic study.

  1962cited by this paper

• Targeting Metabolic Vulnerabilities in Glioblastoma: a Framework for Multi-node Combination Therapy

  2026cites this paper
• Quantitative proteomic analysis reveals different functional subtypes among IDH-wildtype glioblastoma

  2025cites this paper
• The interplay of mitochondrial dysfunction and altered metabolic pathways in glioblastoma

  2025cites this paper
• Quantitative Proteomic Analysis Reveals Different Functional Subtypes among IDH-Wildtype Glioblastoma

  2025cites this paper
• The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

  2025cites this paper
• Mitochondrial Oxidative Phosphorylation Alterations in Placental Tissues from Early- and Late-Onset Preeclampsia

  2025cites this paper
• Metabolic dysregulation of tricarboxylic acid cycle and oxidative phosphorylation in glioblastoma

  2024cites this paper
• Ketogenic metabolic therapy in conjunction with standard treatment for glioblastoma: A case report

  2024cites this paper
• Ketogenic Diet in the Management of Glioblastomas: A Bibliometric Analysis

  2024cites this paper
• Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

  2024cites this paper
• Expanding the phenotypic and biochemical spectrum of NDUFAF3-related mitochondrial disease.

  2023cites this paper
• Parkin exerts the tumor‐suppressive effect through targeting mitochondria

  2023cites this paper
• Ferroptosis determinants - potential therapeutic targets glioblastoma stem cells

  2022cites this paper
• Metabolic management of microenvironment acidity in glioblastoma

  2022cites this paper
• Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity

  2022cites this paper
• Possible new mitochondrial mechanism of vitamin C anticancer activity

  2022cites this paper
• Levels of Coenzyme Q10 and Several COQ Proteins in Human Astrocytoma Tissues Are Inversely Correlated with Malignancy

  2022cites this paper
• A Metabonomic View on Wilms Tumor by High-Resolution Magic-Angle Spinning Nuclear Magnetic Resonance Spectroscopy

  2022cites this paper
• The Big Picture of Glioblastoma Malignancy: A Meta-Analysis of Glioblastoma Proteomics to Identify Altered Biological Pathways

  2021cites this paper
• Revision of commonly accepted Warburg mechanism of cancer development. Redox-sensitive mitochondrial cytochromes in breast and brain cancers by Raman imaging

  2021cites this paper
• GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunction

  2021cites this paper
• Mitochondrial DNA Haplogroups J and T increase the risk of Glioma.

  2021cites this paper
• Mitochondrial Inhibition: a Treatment Strategy in Cancer?

  2021cites this paper
• Case Report and Review of the Literature: A New and a Recurrent Variant in the VARS2 Gene Are Associated With Isolated Lethal Hypertrophic Cardiomyopathy, Hyperlactatemia, and Pulmonary Hypertension in Early Infancy

  2021cites this paper
• Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report

  2021cites this paper
• Mitochondrial DNA Alterations in Glioblastoma (GBM)

  2021influential citation
• Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging

  2021influential citation
• On the Origin of ATP Synthesis in Cancer

  2020cites this paper
• Exploring the crosstalk of glycolysis and mitochondrial metabolism in psychiatric disorders and brain tumours

  2020cites this paper
• Identification of a Metabolism-Related Risk Signature Associated With Clinical Prognosis in Glioblastoma Using Integrated Bioinformatic Analysis

  2020cites this paper
• Redox Imbalance and Biochemical Changes in Cancer by Probing Redox-Sensitive Mitochondrial Cytochromes in Label-Free Visible Resonance Raman Imaging

  2020cites this paper
• Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?

  2019cites this paper
• The vicious circle between mitochondrial oxidative stress and dynamic abnormality mediates triethylene glycol dimethacrylate-induced preodontoblast apoptosis.

  2019cites this paper
• Identification of survival-associated key genes and long non-coding RNAs in glioblastoma multiforme by weighted gene co-expression network analysis

  2019cites this paper
• Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

  2019cites this paper
• From old to new — Repurposing drugs to target mitochondrial energy metabolism in cancer

  2019cites this paper
• The Effect of Mitochondrial DNA Mutations in Brain Tumors

  2019cites this paper
• Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma

  2019cites this paper
• Mutations in NDUFS1 Cause Metabolic Reprogramming and Disruption of the Electron Transfer

  2019cites this paper
• Cell death-based treatment of neuroblastoma

  2018cites this paper
• Reduced Levels of ATP Synthase Subunit ATP5F1A Correlate with Earlier-Onset Prostate Cancer

  2018cites this paper
• Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis

  2018cites this paper
• Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status

  2018cites this paper
• Alterations of the levels of primary antioxidant enzymes in different grades of human astrocytoma tissues

  2018cites this paper
• Mitochondria targeting and its consequences for cell death in neuroblastoma

  2018cites this paper
• Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up

  2018cites this paper
• A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients

  2018cites this paper
• Previously Unreported Biallelic Mutation in DNAJC19: Are Sensorineural Hearing Loss and Basal Ganglia Lesions Additional Features of Dilated Cardiomyopathy and Ataxia (DCMA) Syndrome?

  2017cites this paper
• In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma

  2017cites this paper
• The ketogenic diet is not feasible as a therapy in a CD-1 nu/nu mouse model of renal cell carcinoma with features of Stauffer's syndrome

  2017cites this paper
• VDAC1 is a molecular target in glioblastoma, with its depletion leading to reprogrammed metabolism and reversed oncogenic properties

  2017cites this paper
• Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis

  2017cites this paper
• Biallelic variants in WARS2 encoding mitochondrial tryptophanyl‐tRNA synthase in six individuals with mitochondrial encephalopathy

  2017cites this paper
• LYRM7 - associated complex III deficiency: A clinical, molecular genetic, MR tomographic, and biochemical study.

  2017cites this paper
• Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma

  2017cites this paper
• Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies

  2017cites this paper
• A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model

  2017cites this paper
• Metabolic Reprogramming in Glioma

  2017cites this paper
• Combined Respiratory Chain Deficiency and UQCC2 Mutations in Neonatal Encephalomyopathy: Defective Supercomplex Assembly in Complex III Deficiencies

  2017cites this paper
• 17β-Hydroxysteroid dehydrogenase type 10 predicts survival of patients with colorectal cancer and affects mitochondrial DNA content.

  2016cites this paper
• The diagnostic value and functional roles of phosphoglycerate mutase 1 in glioma.

  2016cites this paper
• Alterations of oxidative phosphorylation in meningiomas and peripheral nerve sheath tumors.

  2016cites this paper
• Atypical Clinical Presentations of TAZ Mutations: An Underdiagnosed Cause of Growth Retardation?

  2016cites this paper
• Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy

  2016cites this paper
• Reducing VDAC1 expression induces a non-apoptotic role for pro-apoptotic proteins in cancer cell differentiation.

  2016cites this paper
• Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model

  2016cites this paper
• A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma

  2016cites this paper
• A comprehensive characterization of mitochondrial DNA mutations in glioblastoma multiforme.

  2015cites this paper
• Metabolic therapy: a new paradigm for managing malignant brain cancer.

  2015cites this paper
• Role of mitochondrial DNA mutations in brain tumors: A mini-review.

  2015cites this paper
• Commentary on “Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme”

  2015cites this paper
• Mutations in TTC19: expanding the molecular, clinical and biochemical phenotype

  2015cites this paper
• Energy metabolism in neuroblastoma and Wilms tumor.

  2015cites this paper
• Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model

  2015cites this paper
• Clinical, morphological, biochemical, imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4 mutations

  2015cites this paper
• Mitochondrial dysfunction in cancer chemoresistance.

  2014cites this paper