The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Cell Science

• Publication date

  2000-12-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11082043
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
• A rapid and sensitive quantitative kinase activity assay using a convenient 96-well format.

  1999influential reference
• Cell regulation: Intracellular networking

  1999cited by this paper
• Reduced expression of (alpha)5(beta)1 integrin prevents spreading-dependent cell proliferation.

  1999influential reference
• Activation of Integrin Signaling Pathways by Cell Interactions with Extracellular Matrix

  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998influential reference
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Anchorage-dependent Cell Cycle Progression

  1997influential reference
• Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events

  1996cited by this paper
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  1996influential reference
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  1996influential reference
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  1995influential reference
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994influential reference
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• Cyclin A is required for the onset of DNA replication in mammalian fibroblasts.

  1991influential reference
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  1981cited by this paper
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  1978cited by this paper

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  2011cites this paper
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  2010cites this paper
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