PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Nuclear Medicine and Biology

• Publication date

  1999-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0969-8051(99)00004-9PMID 10473187
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor

  2005cited by this paper
• SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain

  2005cited by this paper
• Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions.

  1999cited by this paper
• Synthesis and radiolabelling of 2β‐carbomethoxy‐3β‐(3′‐iodo‐4′‐isopropylphenyl) nortropane as a radioligand for the exploration of the serotonin transporter by SPET

  1999cited by this paper
• Iodine-123 labeled nor-β-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography

  1997cited by this paper
• Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective compounds for the dopamine transporter.

  1997cited by this paper
• In vitro and in vivo characterisation of nor-β-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain

  1997cited by this paper
• Improved synthesis of beta-CIT and [11C]beta-CIT labeled at nitrogen or oxygen positions.

  1996cited by this paper
• Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.

  1996cited by this paper
• Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.

  1996cited by this paper
• Synthesis of unlabelled, 3H‐ and 125I‐labelled β‐CIT and its ϖ‐fluoroalkyl analogues β‐CIT‐FE and β‐CIT‐FP, including synthesis of precursors

  1996cited by this paper
• Improved synthesis of β-CIT and [11C]β-CIT labeled at nitrogen or oxygen positions

  1996cited by this paper
• Altered serotonin transporter sites in Alzheimer's disease raphe and hippocampus.

  1995cited by this paper
• Positron Emission Tomography of 5-HT Transporter Sites in the Baboon Brain with [11C]McN5652

  1995cited by this paper
• Altered serotonin transporter sites in Alzheimer's disease raphe and hippocampus

  1995cited by this paper
• Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.

  1995cited by this paper
• Radioligands for PET studies of central 5-HT receptors and re-uptake sites--current status.

  1995cited by this paper
• Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652

  1995cited by this paper
• Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.

  1994cited by this paper
• The ECAT EXACT HR: Performance of a New High Resolution Positron Scanner

  1994cited by this paper
• Metabolism of the PET ligand [11C]SCH 23390. Identification of two radiolabelled metabolites with HPLC

  1994cited by this paper
• Pet study of [11C] β‐CIT binding to monoamine transporters in the monkey and human brain

  1994cited by this paper
• Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter.

  1994cited by this paper
• Novel 2-substituted cocaine analogs: binding properties at dopamine transport sites in rat striatum.

  1993cited by this paper
• Serotonin Uptake Sites and Serotonin Receptors Are Altered in the Limbic System of Schizophrenics

  1993cited by this paper
• Serotoninergic terminal transporters are differentially affected in Parkinson's disease and progressive supranuclear palsy: an autoradiographic study with [3H]citalopram.

  1993cited by this paper
• [125I]RTI-55: a potent ligand for dopamine transporters.

  1991cited by this paper
• Synthesis and receptor binding of N-substituted tropane derivatives. High-affinity ligands for the cocaine receptor.

  1991cited by this paper
• Citalopram: labelling with carbon-11 and evaluation in rat as a potential radioligand for in vivo PET studies of 5-HT re-uptake sites.

  1991cited by this paper
• Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study.

  1990cited by this paper
• Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET.

  1990cited by this paper
• Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen.

  1989cited by this paper
• Presynaptic Serotonergic Dysfunction in Patients with Alzheimer's Disease

  1987cited by this paper
• Compounds affecting the central nervous system. 4. 3 Beta-phenyltropane-2-carboxylic esters and analogs.

  1973cited by this paper

• (11) C and (18) F PET radioligands for the serotonin transporter (SERT).

  2013cites this paper
• Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination?

  2010cites this paper
• Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine.

  2009cites this paper
• Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.

  2008cites this paper
• Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters.

  2005cites this paper
• Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.

  2005cites this paper
• Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.

  2005cites this paper
• [11C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET

  2005cites this paper
• Positron Emission Tomography Agents for Central Nervous System Drug Development Applications

  2005cites this paper
• Imaging serotonin transporters with 123I-ADAM brain SPECT in healthy non-human primates

  2004cites this paper
• S‐[18F]fluoromethyl‐(+)‐McN5652, a PET tracer for the serotonin transporter: Evaluation in rats

  2003cites this paper
• Molecular targeting with radionuclides: state of the science.

  2003cites this paper
• Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter.

  2003cites this paper
• Imaging the Brain Dopamine Transporter Using PET and SPECT

  2002cites this paper
• PET en neurología y psiquiatría II

  2002cites this paper
• Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

  2002cites this paper
• Kinetic Compartment Modeling of [11C]-5-Hydroxy-L-Tryptophan for Positron Emission Tomography Assessment of Serotonin Synthesis in Human Brain

  2002cites this paper
• PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter.

  2002cites this paper
• [PET in neurology and psychiatry. II].

  2002cites this paper
• 123I-ADAM SPECT in healthy nonhuman primates: A preliminary report

  2002cites this paper
• Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter.

  2002cites this paper
• [PET radiopharmaceuticals].

  2001cites this paper
• Carbon-11 labelling of MADAM in two different positions: a highly selective PET radioligand for the serotonin transporter

  2001cites this paper
• Binding characteristics of selective serotonin reuptake inhibitors with relation to emission tomography studies

  2001cites this paper
• Synthesis of S-([18F]fluoromethyl)-(+)-McN5652 as a potential PET radioligand for the serotonin transporter.

  2001cites this paper
• Precursor synthesis and radiolabelling of [11C]ADAM: a potential radioligand for the serotonin transporter exploration by PET

  2001cites this paper
• Brain radioligands--state of the art and new trends.

  2001cites this paper
• Novel Radiotracers for Imaging the Serotonin Transporter by Positron Emission Tomography: Synthesis, Radiosynthesis, and in Vitro and ex Vivo Evaluation of (11)C-Labeled 2-(Phenylthio)araalkylamines.

  2000cites this paper
• Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations.

  2000cites this paper
• PET studies of brain monoamine transporters.

  2000cites this paper
• Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines.

  2000cites this paper