Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  International Journal of Radiation Applications and Instrumentation. Part A: Applied Radiation and Isotopes

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0883-2889(90)90082-RPMID 2170298
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Stereoselective binding of 11C-raclopride in living human brain — a search for extrastriatal central D2-dopamine receptors by PET

  2004cited by this paper
• PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

  2004cited by this paper
• Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.

  1989cited by this paper
• Kinetic Analysis of Central [11C]Raclopride Binding to D2-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

  1989cited by this paper
• 11C-labelling of Ro 15-1788 in two different positions, and also 11C-labelling of its main metabolite Ro 15-3890, for PET studies of benzodiazepine receptors.

  1988cited by this paper
• Raclopride, a new selective ligand for the dopamine-D2 receptors.

  1988cited by this paper
• N 3 fluorine 18 fluoropropylspiperone the preferred fluorine 18 labeled spiperone analog for positron emission tomographic studies of the dopamine receptor

  1988cited by this paper
• N-(3-[18F]fluoropropyl)-spiperone: the preferred 18F labeled spiperone analog for positron emission tomographic studies of the dopamine receptor.

  1988cited by this paper
• Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs.

  1988cited by this paper
• 3-N-(2-[18F]-fluoroethyl)-spiperone: a novel ligand for cerebral dopamine receptor studies with pet.

  1987cited by this paper
• New selective dopamine D-2 antagonists as antipsychotic agents. Pharmacological, chemical, structural and theoretical considerations.

  1987cited by this paper
• The synthesis of 1-11C-labelled ethyl, propyl, butyl and isobutyl iodides and examples of alkylation reactions

  1986cited by this paper
• Syntheses and D2 receptor affinities of derivatives of spiperone containing aliphatic halogens.

  1986cited by this paper
• Improved delineation of human dopamine receptors using [18F]-N-methylspiroperidol and PET.

  1986cited by this paper
• Quantitative analysis of D2 dopamine receptor binding in the living human brain by PET.

  1986cited by this paper
• Potential neuroleptic agents. 4. Chemistry, behavioral pharmacology, and inhibition of [3H]spiperone binding of 3,5-disubstituted N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxysalicylamides.

  1986cited by this paper
• Imaging of neurotransmitter receptors in the living human brain.

  1986cited by this paper
• Potential Neuroleptic Agents. Part 4. Chemistry, Behavioral Pharmacology and Inhibition of [3H]Spiperone Binding of 3,5‐Disubstituted N‐[(1‐Ethyl‐2‐pyrrolidinyl)methyl]‐6‐methoxysalicylamides.

  1986cited by this paper
• Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography.

  1985cited by this paper
• Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain.

  1985cited by this paper
• SYNTHESIS, CRYSTAL STRUCTURE AND ANTIDOPAMINERGIC PROPERTIES OF ETICLOPRIDE (FLB 131)

  1985cited by this paper
• Performance Study of the PC‐384 Positron Camera System for Emission Tomography of the Brain

  1984cited by this paper
• Imaging dopamine receptors in the human brain by positron tomography.

  1984cited by this paper
• Imaging dopamine receptors in the human brain by positron tomography

  1983cited by this paper
• Multiple receptors for dopamine

  1979cited by this paper

• Reaction rate constant: a theoretical description from local temperature.

  2024cites this paper
• Allosteric Interactions between Adenosine A2A and Dopamine D2 Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging

  2021cites this paper
• Imaging in drug development.

  2015cites this paper
• Radioligands for the dopamine receptor subtypes.

  2013cites this paper
• Potential Effects of Vinpocetine on Psychomotor Performances and Cognitive Function Capability in Normal Healthy Volunteers: Randomized Clinical Trail

  2012cites this paper
• A Review of the Discovery, Pharmacological Characterization, and Behavioral Effects of the Dopamine D2‐Like Receptor Antagonist Eticlopride

  2008cites this paper
• [11C]Carbon monoxide, a versatile and useful precursor in labelling chemistry for PET‐ligand development

  2007cites this paper
• Selective synthesis of [2-(11)C]2-iodopropane and [1-(11)C]iodoethane using the loop method by reacting methylmagnesium bromide with [11C]carbon dioxide.

  2006cites this paper
• Synthesis of [1‐11C]propyl and [1‐11C]butyl iodide from [11C]carbon monoxide and their use in alkylation reactions

  2006cites this paper
• Eburnamine derivatives and the brain

  2005cites this paper
• NCQ 298, a new selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors

  2005cites this paper
• Positron Emission Tomography and Single Photon Emission Tomography Imaging of Cerebral D, Dopamine Receptors

  2004cites this paper
• Safety-catch linker strategies for the production of radiopharmaceuticals labeled with positron-emitting isotopes.

  2003cites this paper
• PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects

  2002cites this paper
• Autoradiographic Evaluation of [^11 C] Vinpocetine Binding in the Human Postmortem Brain

  2002cites this paper
• Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine

  2002cites this paper
• Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors.

  1999cites this paper
• Brain Uptake and Plasma Metabolism of [11C]Vinpocetine: A Preliminary PET Study in a Cynomolgus Monkey

  1999cites this paper
• Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions.

  1999cites this paper
• PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter.

  1999cites this paper
• Improved syntheses of the PET radioligands, [11C]FLB 457, [11C]MDL 100907 and [11C]β‐CIT‐FE, by the use of [11C]methyl triflate

  1998cites this paper
• Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors.

  1998cites this paper
• [11C]NNC 22-0215, a metabolically stable dopamine D1 radioligand for PET.

  1998cites this paper
• A PET Study of 5-HT2 and D2 Dopamine Receptor Occupancy Induced by Olanzapine in Healthy Subjects

  1997cites this paper
• Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635.

  1997cites this paper
• Bromine-76 and carbon-11 labelled NNC 13-8199, metabolically stable benzodiazepine receptor agonists as radioligands for positron emission tomography (PET)

  1997cites this paper
• 11C- and 76Br-labelled NNC 22-0010, selective dopamine D1 receptor radioligands for PET.

  1996cites this paper
• [11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography.

  1996cites this paper
• [11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey.

  1996cites this paper
• [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations.

  1995cites this paper
• No-carrier-added (NCA) synthesis of 6-[18F]fluoro-L-DOPA using 3,5,6,7,8,8a-hexahydro-7,7,8a-trimethyl-[6S-(6α, 8α, 8αβ)]-6,8-methano-2H-1,4-benzoxazin-2-one

  1995cites this paper
• Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate.

  1995cites this paper
• Preparation of a potential positron emission tomographic radioligand for the dopamine transporter

  1994cites this paper
• Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane.

  1994cites this paper
• PET analysis of [11C]flumazenil binding to benzodiazepine receptors in chronic alcohol-dependent men and healthy controls.

  1993cites this paper
• [11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey.

  1993cites this paper
• [11C] beta-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations.

  1993cites this paper
• Correlation of Reaction Rates with a Substituent Constant Scale Derived from Calculated Electron Densities for a Computer Control Algorithm

  1993cites this paper
• (S)- and (R)-[11C]nicotine and the metabolite (R/S)-[11C]cotinine. Preparation, metabolite studies and in vivo distribution in the human brain using PET.

  1992cites this paper
• PET radioligands for dopamine receptors and re-uptake sites: chemistry and biochemistry.

  1992cites this paper
• Imaging of dopamine receptors using PET and SPECT.

  1992cites this paper
• [11C]Ro 15-4513, a ligand for visualization of benzodiazepine receptor binding

  1992cites this paper
• In vivo studies of [125I]iodobenzamide and [11C]iodobenzamide: A ligand suitable for positron emission tomography and single photon emission tomography imaging of cerebral D2 dopamine receptors

  1992cites this paper
• Carbon-11 Radiopharmaceuticals - Radiopharmacy Aspects

  1992cites this paper
• Synthesis of racemic [α-11C]amphetamine and [α-11C]phenethylamine from [11C]nitroalkanes

  1992cites this paper
• Tracers for metabolic imaging of brain and heart

  1992cites this paper
• Synthesis of N‐[11C]‐methyl‐L‐DOPA

  1992cites this paper
• Synthesis of carbon-11 labelled SCH 39166, a new selective dopamine D-1 receptor ligand, and preliminary PET investigations.

  1991cites this paper
• Positron emission tomography studies of brain receptors

  1991cites this paper
• A comparative PET-study of five carbon-11 or fluorine-18 labelled salicylamides. Preparation and in vitro dopamine D-2 receptor binding.

  1991cites this paper
• Synthesis of [1-11C]D-glucose and [1-11C]D-mannose from on-line produced [11C]nitromethane.

  1991cites this paper
• Structural and functional brain imaging in schizophrenia.

  1991cites this paper
• Fluorinated benzamide neuroleptics--2. Synthesis and radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-3- substituted-2-methoxybenzamides.

  1991cites this paper
• Radioligands for Dopamine Receptor PET Studies: Benzamides and Ligands for Dopamine D-1 Receptors

  1991cites this paper