Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Trends in Genetics

• Publication date

  1998-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0168-9525(98)01473-5PMID 9635407
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2

  1998cited by this paper
• A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.

  1998cited by this paper
• Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of the p25rum1 CDK inhibitor

  1998cited by this paper
• Budding yeast RSI1/APC2, a novel gene necessary for initiation of anaphase, encodes an APC subunit

  1998cited by this paper
• Budding yeast Cdc20: a target of the spindle checkpoint.

  1998cited by this paper
• Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint.

  1998cited by this paper
• Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

  1998cited by this paper
• Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

  1998cited by this paper
• Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

  1998cited by this paper
• Association of human CUL‐1 and ubiquitin‐conjugating enzyme CDC34 with the F‐box protein p45SKP2: evidence for evolutionary conservation in the subunit composition of the CDC34–SCF pathway

  1998cited by this paper
• The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p.

  1998cited by this paper
• Proteolysis and the G1-S transition: the SCF connection.

  1998cited by this paper
• The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal.

  1998cited by this paper
• Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.

  1998cited by this paper
• Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

  1997cited by this paper
• Protein translocation channels in the proteasome and other proteases.

  1997cited by this paper
• Extinction is forever.

  1997cited by this paper
• Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22

  1997cited by this paper
• Roles of ubiquitin-mediated proteolysis in cell cycle control.

  1997cited by this paper
• Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.

  1997cited by this paper
• p25rum1 promotes proteolysis of the mitotic B‐cyclin p56cdc13 during G1 of the fission yeast cell cycle

  1997cited by this paper
• Yeast Hct1 is a regulator of Clb2 cyclin proteolysis.

  1997cited by this paper
• Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation.

  1997cited by this paper
• β‐catenin is a target for the ubiquitin–proteasome pathway

  1997cited by this paper
• A novel ubiquitin‐specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

  1997cited by this paper
• Eliminating all obstacles: regulated proteolysis in the eukaryotic cell cycle.

  1997cited by this paper
• Dynamics of proteasome distribution in living cells

  1997cited by this paper
• A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

  1997cited by this paper
• A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS.

  1997cited by this paper
• F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

  1997cited by this paper
• The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae.

  1997cited by this paper
• Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

  1997cited by this paper
• Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast.

  1997cited by this paper
• Dual role for fimbriata in regulating floral homeotic genes and cell division in Antirrhinum

  1997cited by this paper
• The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

  1997cited by this paper
• sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins.

  1997cited by this paper
• beta-catenin is a target for the ubiquitin-proteasome pathway.

  1997cited by this paper
• Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle

  1997cited by this paper
• Identification of a novel nuclear speckle‐type protein, SPOP

  1997cited by this paper
• CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

  1997cited by this paper
• Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase.

  1997cited by this paper
• Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle.

  1997cited by this paper
• Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation.

  1997cited by this paper
• The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.

  1997cited by this paper
• A novel ubiquitin‐specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

  1997cited by this paper
• SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

  1996cited by this paper
• The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.

  1996cited by this paper
• Linkage of Replication to Start by the Cdk Inhibitor Sic1

  1996cited by this paper
• cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.

  1996cited by this paper
• Budding Yeast SKP1 Encodes an Evolutionarily Conserved Kinetochore Protein Required for Cell Cycle Progression

  1996cited by this paper
• Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.

  1996cited by this paper
• Genetics of obesity: advances from rodent studies.

  1996cited by this paper
• Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

  1996cited by this paper
• Rapid Degradation of the G1 Cyclin Cln2 Induced by CDK-Dependent Phosphorylation

  1996cited by this paper
• Ubiquitin-dependent protein degradation.

  1996cited by this paper
• The Saccharomyces cerevisiae kinetochore contains a cyclin‐CDK complexing homologue, as identified by in vitro reconstitution.

  1996cited by this paper
• The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start.

  1996cited by this paper
• A heteromeric complex containing the centromere binding factor 1 and two basic leucine zipper factors, Met4 and Met28, mediates the transcription activation of yeast sulfur metabolism.

  1996cited by this paper
• Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme

  1995cited by this paper
• The sulfur controller-2 negative regulatory gene of Neurospora crassa encodes a protein with beta-transducin repeats.

  1995cited by this paper
• Tetratrico peptide repeat interactions: to TPR or not to TPR?

  1995cited by this paper
• Ubiquitination of the G1 cyclin Cln2p by a Cdc34p‐dependent pathway.

  1995cited by this paper
• p34Cdc28-mediated control of Cln3 cyclin degradation

  1995cited by this paper
• Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats

  1995cited by this paper
• G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast.

  1995cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• The leucine-rich repeat: a versatile binding motif.

  1994cited by this paper
• The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae.

  1994cited by this paper
• The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.

  1994cited by this paper
• The ancient regulatory-protein family of WD-repeat proteins

  1994cited by this paper
• Drosophila kelch motif is derived from a common enzyme fold.

  1994cited by this paper
• Regulated degradation of the transcription factor Gcn4.

  1994cited by this paper
• At least four regulatory genes control sulphur metabolite repression in Aspergillus nidulans

  1993cited by this paper
• Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

  1983cited by this paper

• Persicaria minor F-box protein, PmFBK2 targeted by miR156a in response to MeJA treatment, potentially affects stress-related proteins.

  2025cites this paper
• LATS2 condensates organize signalosomes for Hippo pathway signal transduction

  2024cites this paper
• Genome-wide association analysis reveals genetic architecture of growth and inner shell color traits in freshwater pearl mussel Hyriopsis cumingii (Lea 1852)

  2024cites this paper
• Characterization of the F-Box Gene Family and Its Expression under Osmotic Stress in Birch

  2023cites this paper
• Cowpox Viruses: A Zoo Full of Viral Diversity and Lurking Threats

  2023cites this paper
• Systematic characterization of Ustilago maydis sirtuins shows Sir2 as a modulator of pathogenic gene expression

  2023cites this paper
• F-box receptor mediated control of substrate stability and subcellular location organizes cellular development of Aspergillus nidulans

  2022cites this paper
• Genome-wide association mapping reveals genes underlying population-level metabolome diversity in a fungal crop pathogen

  2022cites this paper
• HOS15 is a transcriptional corepressor of NPR1-mediated gene activation of plant immunity

  2020cites this paper
• Validation of a QTL for Grain Size and Weight Using an Introgression Line from a Cross between Oryza sativa and Oryza minuta

  2020cites this paper
• TaAPO-A1, an ortholog of rice ABERRANT PANICLE ORGANIZATION 1, is associated with total spikelet number per spike in elite European hexaploid winter wheat (Triticum aestivum L.) varieties

  2019cites this paper
• Decrypting tubby-like protein gene family of multiple functions in starch root crop cassava

  2019cites this paper
• Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron

  2018cites this paper
• The tubby-like proteins kingdom in animals and plants.

  2018cites this paper
• OsRALyasel , a Putative F-Box Protein with Enzyme Activity Identical to That JSem Identified in Rice , Oi : yza sativa , of Wheat RALyase

  2018cites this paper
• LMO7 exerts an effect on mitosis progression and the spindle assembly checkpoint.

  2018cites this paper
• Survival Motor Neuron protein interaction partners in Drosophila melanogster

  2018cites this paper
• Functional and Structural Characterization Reveals Novel FBXW7 Biology

  2018cites this paper
• Evolutionary conservation and functional divergence of the LFK gene family play important roles in the photoperiodic flowering pathway of land plants

  2017cites this paper
• The role of atypical ubiquitination in cell regulation

  2017cites this paper
• Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase Machinery*

  2017cites this paper
• Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCFSlmb degron

  2017cites this paper
• Analysis of CFB, a cytokinin-responsive gene of Arabidopsis thaliana encoding a novel F-box protein regulating sterol biosynthesis

  2017cites this paper
• Plant Efficacy and Alkaloids Production in Sadabahar (Catharanthus roseus L.): Role of Potent PGRs and Mineral Nutrients

  2017cites this paper
• The vascular plants: open system of growth

  2017cites this paper
• CKS1 expression in melanocytic nevi and melanoma

  2017cites this paper
• Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma

  2017cites this paper
• University of Dundee Self-oligomerization regulates stability of Survival Motor Neuron ( SMN ) protein isoforms by sequestering an SCFSlmb

  2017cites this paper
• SCFSlmb recognizes a conserved degron within the survival motor neuron (SMN) self-interaction domain to mediate ubiquitylation of SMN and SMNΔ7 isoforms

  2016cites this paper
• Molecular retention mechanisms of the G1 cyclin/Cdk complex in budding yeast

  2016cites this paper
• [Atypical ubiquitination of proteins].

  2016cites this paper
• 12 Regulation of Sulfur Metabolism in Filamentous Fungi

  2016cites this paper
• Wheat MATH-BTB proteins and their role in early embryogenesis

  2016cites this paper
• Interactions between wheat Tubby-like and SKP1-like proteins.

  2015cites this paper
• Cdk1-Dependent Phosphorylation of the APC-Cdc20 Regulates its Activation at Anaphase Onset in S. cerevisiae

  2015cites this paper
• CHARACTERIZATION OF MITOTIC REGULATORS ACM1 AND CDC14

  2015cites this paper
• The F-box family genes as key elements in response to salt, heavy mental, and drought stresses in Medicago truncatula

  2015cites this paper
• Exploring the role of genomic instability in cancer and neurodegenerative disease through mouse models

  2015cites this paper
• Assaying proteasomal degradation in a cell-free system in plants.

  2014cites this paper
• Mining real-world networks in systems biology and economics

  2014cites this paper
• Cáncer del epitelio folicular tiroideo: identificación de procesos biológicos, marcadores moleculares y nuevas dianas terapéuticas

  2014cites this paper
• Protein degradation machinery is present broadly during early development in the sea urchin.

  2014cites this paper
• Sex differences in body composition, fat storage, and gene expression profile in Caenorhabditis elegans in response to dietary restriction.

  2013cites this paper
• HORMONE EPIMERS REGULATE ER STRESS AND CORE REGULATORY GENES: NETWORK ANALYSIS WITH APPLICATIONS TO GLIOMA AND CHRONIC PRESSURE ULCERS

  2013cites this paper
• Identification Of Candidate Genes For Self-Compatibility In A Diploid Population Of Potato Derived From Parents Used In Genome Sequencing

  2013influential citation
• The role of genes co-amplified with nicastrin in breast invasive carcinoma

  2013cites this paper
• PP2ACdc55 regulates G1 cyclin stability

  2013cites this paper
• Identification of differentially expressed genes in 72 h styles from self-incompatible Citrus reticulata

  2013cites this paper
• A Novel Wheat Related-to-Ubiquitin Gene TaRUB1 is Responsive to Pathogen Attack as Well as to Both Osmotic and Salt Stress

  2013cites this paper
• The eta7/csn3-3 Auxin Response Mutant of Arabidopsis Defines a Novel Function for the CSN3 Subunit of the COP9 Signalosome

  2013cites this paper
• El sistEma ubicuitina/protEasoma En la intEracción planta-patógEno

  2013cites this paper
• Genome-wide identification and characterisation of F-box family in maize

  2013cites this paper
• Insulin Resistance and Muscle Metabolism in Chronic Kidney Disease

  2013cites this paper
• Hormonal interactions and gene regulation can link monoecy and environmental plasticity to the evolution of dioecy in plants.

  2013cites this paper
• A global requirement for the HIR complex in the assembly of chromatin.

  2012cites this paper
• Molecular characterization of the Aspergillus nidulans fbxA encoding an F-box protein involved in xylanase induction.

  2012cites this paper
• Investigation of the mitochondrial functions of proteins genetically associated with Parkinson's Disease

  2012cites this paper
• Neurogenetics: A Guide for Clinicians

  2012cites this paper
• Morphogenesis in Paracoccidioides brasiliensis

  2012cites this paper
• APC/β-Catenin Deregulation in Desmoid Tumors: Important Implications for Diagnosis, Prognosis, and Therapy

  2012cites this paper
• Interaction analyses of Arabidopsis tubby-like proteins with ASK proteins

  2012cites this paper
• The mitotic Clb cyclins are required to alleviate HIR-mediated repression of the yeast histone genes at the G1/S transition.

  2012cites this paper
• Disassembly of synthetic Agrobacterium T-DNA–protein complexes via the host SCFVBF ubiquitin–ligase complex pathway

  2012cites this paper
• A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila.

  2012cites this paper
• Identification of a ubiquitin-binding structure in the S-locus F-box protein controlling S-RNase-based self-incompatibility.

  2012influential citation
• Sex differences in Caenorhabditis elegans in body composition, lipid storage and gene expression under ad libitum and dietary restriction conditions

  2012cites this paper
• Theoretical and Experimental Investigation of Switch-Like Responses Arising from Multisite Protein Phosphorylation.

  2011cites this paper
• Integrative Identification of Arabidopsis Mitochondrial Proteome and Its Function Exploitation through Protein Interaction Network

  2011cites this paper
• Caractérisation biochimique et moléculaire du complexe SCF (SKP1-CULLIN-FBOX) chez le blé tendre

  2011cites this paper
• The F-box Protein FSN-1 Governs Presynaptic Development in Caenorhabditis elegans

  2011cites this paper
• The Anaphase-Promoting Complex Interacts with Histone Modification Proteins and Chromatin Assembly Factors

  2011cites this paper
• Effects of Dietary Leucine Supplementation on Muscle Mass and Markers of Protein Degradation in Overloaded Skeletal Muscles of Young Adult and Aged Rats

  2011cites this paper
• Cell Cycle Regulatory Roles of Estrogen Receptor alpha (ERα) in Breast Cancer Cells

  2011cites this paper
• Molecular analysis and expression of a floral organ-relative F-box gene isolated from ‘Zigui shatian’ pummelo (Citrus grandis Osbeck)

  2011cites this paper
• Nucleolar Targeting of the Fbw7 Ubiquitin Ligase by a Pseudosubstrate and Glycogen Synthase Kinase 3

  2011cites this paper
• Analysis of differentially expressed genes in leaf rust infected bread wheat involving seedling resistance gene Lr28.

  2011cites this paper
• The Ubiquitin-Proteasome System and F-box Proteins in Pathogenic Fungi

  2011cites this paper
• The auxin receptor homologue in Solanum lycopersicum stimulates tomato fruit set and leaf morphogenesis.

  2011cites this paper
• Neddylation and CAND1 Independently Stimulate SCF Ubiquitin Ligase Activity in Candida albicans

  2011cites this paper
• Remodelling the Oocyte into a Totipotent Zygote: Degradation of Maternal Products

  2010cites this paper
• Multisite Phosphorylation Provides an Effective and Flexible Mechanism for Switch-Like Protein Degradation

  2010cites this paper
• Regulation of Pcl6 and Pcl7 in a Glc7 pathway in Saccharomyces cerevisiae

  2010cites this paper
• Recent Developments in the Molecular Biology of Pituitary Tumors

  2010cites this paper
• Corepressors in Mediating Repression by Nuclear Receptors

  2010cites this paper
• Phototropism: Mechanism and Outcomes

  2010cites this paper
• Recognition of Phospho-Serine/Threonine Phosphorylated Proteins by Phospho-Serine/Threonine-Binding Domains

  2010cites this paper
• FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest

  2010cites this paper
• ARABIDILLO proteins have a novel and conserved domain structure important for the regulation of their stability

  2010cites this paper
• The Molecular Biology of Flowering

  2010cites this paper
• Role of CenH3/CENP-A in the regulation of centromere function and chromosome segregation

  2010cites this paper
• Role of CenH3/CENP-A in the regulation of centromere function and chromosome segregation

  2010cites this paper
• Comparative analysis of the discordance between the global transcriptional and proteomic response of the yeast Saccharomyces cerevisiae to deletion of the F-box protein, Grr1

  2010cites this paper
• Coupling histone homeostasis to centromere integrity via the ubiquitin-proteasome system

  2010cites this paper
• Isolation, Characterization, and Expression Analysis of an SKP1-like Gene from ‘Shatian’ Pummelo (Citrus grandis Osbeck)

  2010cites this paper
• Hsk1- and SCFPof3-Dependent Proteolysis of S. pombe Ams2 Ensures Histone Homeostasis and Centromere Function

  2010cites this paper
• Chapter 255 – Ubiquitination/Proteasome

  2010cites this paper
• Proteasomal degradation in plant-pathogen interactions.

  2009cites this paper
• PROTEINS THAT INTERACT WITH UBIQUITrN-CONJUGATING E N Z Y M E 2, UBC-2, IN THE N E M A T O D E CAENORHABDITIS ELEGANS

  2009cites this paper
• Genomic and functional characterization of StCDPK1

  2009cites this paper
• The role of the F-Box protein Frp1 in pathogenicity of fusarium oxysporum

  2009cites this paper