Binding of the human E2F transcription factor to the retinoblastoma protein but not to cyclin A is abolished in HPV-16-immortalized cells.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Oncogene

• Publication date

  1992-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 1323816
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner.

  1992cited by this paper
• Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F

  1992cited by this paper
• A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

  1992cited by this paper
• Association of cdk2 kinase with the transcription factor E2F during S phase.

  1992cited by this paper
• Cyclin A is required at two points in the human cell cycle.

  1992cited by this paper
• The retinoblastoma protein physically associates with the human cdc2 kinase

  1992cited by this paper
• Cellular localization and T antigen binding of the retinoblastoma protein.

  1992cited by this paper
• The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein.

  1991cited by this paper
• Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells

  1991cited by this paper
• Viral transcription in human keratinocyte cell lines immortalized by human papillomavirus type-16.

  1991cited by this paper
• Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

  1991cited by this paper
• The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F.

  1991cited by this paper
• The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle.

  1991cited by this paper
• The E2F transcription factor is a cellular target for the RB protein.

  1991cited by this paper
• Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.

  1991cited by this paper
• Cyclin A and the retinoblastoma gene product complex with a common transcription factor

  1991cited by this paper
• Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

  1991cited by this paper
• Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

  1990cited by this paper
• Differential activation of the E2F transcription factor by the adenovirus EIa and EIV products in F9 cells.

  1990cited by this paper
• Two distinct cellular proteins interact with the EIa-responsive element of an adenovirus early promoter

  1990cited by this paper
• A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.

  1990cited by this paper
• Cooperative binding of two E2F molecules to an Ela‐responsive promoter is triggered by the adenovirus Ela, but not by a cellular Ela‐like activity.

  1989cited by this paper
• The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.

  1989cited by this paper
• Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo

  1989cited by this paper
• The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding

  1989cited by this paper
• The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.

  1989cited by this paper
• A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells.

  1989cited by this paper
• HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.

  1989cited by this paper
• SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.

  1988cited by this paper
• A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins.

  1988cited by this paper
• The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.

  1988cited by this paper
• Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

  1988cited by this paper
• Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

  1988cited by this paper
• Multiple functional domains in the adenovirus E1A gene.

  1987cited by this paper
• Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells.

  1987cited by this paper
• Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA.

  1987cited by this paper
• p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.

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  2009cites this paper
• The high risk human papillomaviruses and oral cancer: evidence for and against a causal relationship.

  2008cites this paper
• The multiple roles of cyclin E1 in controlling cell cycle progression and cellular morphology of Trypanosoma brucei.

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• Rb Inactivation Leads to E2F1-mediated DNA Double Strand Break Accumulation: A Dissertation

  2006cites this paper
• Roots and perspectives of contemporary papillomavirus research

  2005cites this paper
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• ImpactofTransforming Viruses onCellular Mutagenesis,GenomeStability,andCellular Transformation

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  1995cites this paper
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