Formation of Methyl Mercaptan froml-Methionine by Porphyromonas gingivalis

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Infection and Immunity

• Publication date

  2000-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.68.12.6912-6916.2000PMID 11083813PMCID PMC97798
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• The Primitive Protozoon Trichomonas vaginalisContains Two Methionine γ-Lyase Genes That Encode Members of the γ-Family of Pyridoxal 5′-Phosphate-dependent Enzymes*

  1998cited by this paper
• The primitive protozoon Trichomonas vaginalis contains two methionine gamma-lyase genes that encode members of the gamma-family of pyridoxal 5'-phosphate-dependent enzymes.

  1998cited by this paper
• Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy.

  1997cited by this paper
• Breath odor: etiopathogenesis, assessment and management.

  1997cited by this paper
• Exposure of Periodontal Ligament Cells to Methyl Mercaptan Reduces Intracellular pH and Inhibits Cell Migration

  1996cited by this paper
• Effect of methyl mercaptan on synthesis and degradation of collagen.

  1996cited by this paper
• Gene cloning and characterization of Pseudomonas putida L-methionine-alpha-deamino-gamma-mercaptomethane-lyase.

  1996cited by this paper
• Gene Cloning and Characterization of Pseudomonas putida l-Methionine-α-deamino-γ-mercaptomethane-lyase

  1996cited by this paper
• Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene

  1995cited by this paper
• Structural analysis of the L-methionine gamma-lyase gene from Pseudomonas putida.

  1995cited by this paper
• Stimulation of enzyme and cytokine production by methyl mercaptan in human gingival fibroblast and monocyte cell cultures.

  1995cited by this paper
• Construction and Characterization of Arginine-specific Cysteine Proteinase (Arg-gingipain)-deficient Mutants of Porphyromonas gingivalis

  1995cited by this paper
• Structural Analysis of the L-Methionine γ-Lyase Gene from Pseudomonas putida

  1995cited by this paper
• Biochemical and clinical factors influencing oral malodor in periodontal patients.

  1992cited by this paper
• Characterization of volatile sulphur compounds production at individual gingival crevicular sites in humans.

  1992cited by this paper
• Modulation of human gingival fibroblast cell metabolism by methyl mercaptan.

  1992cited by this paper
• Effect of volatile thiol compounds on protein metabolism by human gingival fibroblasts.

  1992cited by this paper
• The formation of hydrogen sulfide and methyl mercaptan by oral bacteria.

  1990cited by this paper
• Production of volatile sulfur compounds by various Fusobacterium species.

  1990cited by this paper
• Heterogeneity of virulence among strains of Bacteroides gingivalis.

  1989cited by this paper
• The capacity of subgingival microbiotas to produce volatile sulfur compounds in human serum.

  1989cited by this paper
• Isolation of intact high-molecular-weight DNA by using guanidine isothiocyanate

  1987cited by this paper
• Effect of Hydrogen Sulfide and Methyl Mercaptan on the Permeability of Oral Mucosa

  1984cited by this paper
• Isolation and Purification of l-Methionine-α-deamino-γ-mercaptomethane-Lyase (l-Methioninase) from Clostridium sporogenes

  1973cited by this paper
• Isolation and purification of L-methionine-alpha-deamino-gamma-mercaptomethane-lyase (L-methioninase) from Clostridium sporogenes.

  1973cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970influential reference

• Methionine challenge test: methyl mercaptan (CH₃SH) response in periodontitis

  2026cites this paper
• Porphyromonas gingivalis and Human Cytomegalovirus Co-Infection: A Potential Link Between Periodontal Disease and Oral Cancer Development

  2025cites this paper
• L-methioninase: a mini review

  2025cites this paper
• Suppressive Effects of Kouboku on Methyl Mercaptan Production and Biofilm Formation in Porphyromonas gingivalis

  2025influential citation
• The immediate effectiveness of a multi-channeled oral irrigator in reducing dental plaque and oral malodor: A preliminary single-blind clinical trial

  2025cites this paper
• A dynamic model for the prediction of malodorous compounds production from anaerobic methanogenic biofilm

  2025cites this paper
• Tongue coating metabolic profiles of intra-oral halitosis patients.

  2024cites this paper
• Interspecies metabolite transfer fuels the methionine metabolism of Fusobacterium nucleatum to stimulate volatile methyl mercaptan production

  2024cites this paper
• A review on L-methioninase in cancer therapy: Precision targeting, advancements and diverse applications for a promising future.

  2024cites this paper
• Niche-Aware Metagenomic Screening for Enzyme Methioninase Illuminates Its Contribution to Metabolic Syntrophy

  2024cites this paper
• Citrobacter freundii Methionine γ-Lyase: The Role of Serine 339 in the Catalysis of γ- and β-Elimination Reactions

  2022cites this paper
• Role of Hydrogen Sulfide in Oral Disease

  2022cites this paper
• Methyl mercaptan gas: mechanisms of toxicity and demonstration of the effectiveness of cobinamide as an antidote in mice and rabbits

  2022cites this paper
• A critical review of prospects and operational challenges of microaeration and iron dosing for in-situ biogas desulfurization

  2022cites this paper
• Emission of volatile sulphur compounds during swine manure composting: Source identification, odour mitigation and assessment.

  2022cites this paper
• Inhibitory effect of black cumin (Nigella sativa) seed essential oil on Fusobacterium nucleatum L-methionine-γ-lyase (L-methioninase) activity.

  2021cites this paper
• Comprehensive Approach of 19F Nuclear Magnetic Resonance, Enzymatic, and In Silico Methods for Site-Specific Hit Selection and Validation of Fragment Molecules that Inhibit Methionine γ-Lyase Activity.

  2021cites this paper
• Characterization and application of l-methionine γ-lyase Q349S mutant enzyme with an enhanced activity toward l-homocysteine.

  2021cites this paper
• Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update

  2021cites this paper
• Effects of volatile sulfur compounds on growth and oxidative stress of Rhizobium leguminosarum E20-8 exposed to cadmium.

  2021cites this paper
• [Research progress on the regulation of phenolic compounds of traditional Chinese herbs on oral microbes].

  2020cites this paper
• Correlations between Hydrogen Sulfide and Methyl Mercaptan Levels and the Proportion of Porphyromonas Gingivalis in Patients with Periodontitis

  2020cites this paper
• Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine γ-lyase. Structural bases of the enzyme inactivation.

  2019cites this paper
• On-line profiling of volatile compounds produced in vitro by pathogenic oral bacteria

  2019cites this paper
• METase promotes cell autophagy via promoting SNHG5 and suppressing miR-20a in gastric cancer.

  2019cites this paper
• Relationship of tongue coating microbiome on volatile sulfur compounds in healthy and halitosis adults

  2019cites this paper
• Induction and inhibition of oral malodor.

  2019cites this paper
• Microbial sources and some therapeutic applications of L-methioninase

  2019cites this paper
• Porphyromonas gingivalis hydrogen sulfide enhances methyl mercaptan-induced pathogenicity in mouse abscess formation.

  2018cites this paper
• Involvement of PorK, a component of the type IX secretion system, in Prevotella melaninogenica pathogenicity

  2018cites this paper
• Antibacterial Activity of Partially Oxidized Ag/Au Nanoparticles against the Oral Pathogen Porphyromonas gingivalis W83

  2018cites this paper
• Emission characteristics of volatile sulfur compounds (VSCs) from a municipal sewage sludge aerobic composting plant.

  2018cites this paper
• Chemical composition of garlic wood (Gallesia integrifolia) (Phytolaccaceae) volatile compounds and their activity on cattle tick

  2017cites this paper
• Isolation and characterization of methanethiol-producing bacteria from agricultural soils

  2017cites this paper
• Recombinant Sox Enzymes from Paracoccus pantotrophus Degrade Hydrogen Sulfide, a Major Component of Oral Malodor

  2017cites this paper
• An extensive review on L-methioninase and its potential applications

  2017cites this paper
• Novel reuterin-related compounds suppress odour by periodontopathic bacteria.

  2017cites this paper
• X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyase

  2017cites this paper
• Mechanistic insights into the γ-elimination reaction of l-methionine catalyzed by methionine γ-lyase (MGL)

  2017cites this paper
• Structural and mechanistic insights into homocysteine degradation by a mutant of methionine γ‐lyase based on substrate‐assisted catalysis

  2017cites this paper
• Assessing iron and aluminum-based coagulants for odour and pathogen reductions in sludge digesters and enhanced digestate dewaterability.

  2017cites this paper
• Chronic Inflammation and Carcinogenesis - Emerging Role of Chronic Inflammatory Periodontal Disease

  2016cites this paper
• In Vitro Effect of Porphyromonas gingivalis Methionine Gamma Lyase on Biofilm Composition and Oral Inflammatory Response

  2016cites this paper
• A continuous spectrophotometric assay and nonlinear kinetic analysis of methionine γ-lyase catalysis.

  2016cites this paper
• Halitosis: Its Intraoral Factors and Mechanism Relating to Formation

  2016influential citation
• Therapeutic oral rinsing Dental clients' perceptions of dental hygienists with visible tattoos Efficacy of sodium chlorite plus zinc gluconate on volatile sulfur compound halitosis Current status of the classification of periodontal diseases

  2016cites this paper
• Engineered Citrobacter freundii methionine γ-lyase effectively produces antimicrobial thiosulfinates.

  2016cites this paper
• Structure of methionine γ-lyase from Clostridium sporogenes.

  2016cites this paper
• Identification and Characterization of a Methionine γ‐Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora

  2015cites this paper
• Sulfoxides, Analogues of L-Methionine and L-Cysteine As Pro-Drugs against Gram-Positive and Gram-Negative Bacteria

  2015cites this paper
• The differential expression of mgl mRNA by Porphyromonas gingivalis affects the production of methyl mercaptan.

  2015influential citation
• Dental Infection of Porphyromonas gingivalis Induces Preterm Birth in Mice

  2015cites this paper
• Effects of metal salt addition on odor and process stability during the anaerobic digestion of municipal waste sludge.

  2015cites this paper
• Antimicrobial effectiveness of cetylpyridinium chloride and zinc chloride-containing mouthrinses on bacteria of halitosis and peri-implant disease.

  2015cites this paper
• Les polyphénols du thé vert : des molécules à double action contre la maladie parodontale

  2015cites this paper
• Oral malodorous gases and oral microbiota: From halitosis to carcinogenesis

  2015cites this paper
• l-Methioninase from some Streptomyces isolates I: Isolation, identification of best producers and some properties of the crude enzyme produced

  2015cites this paper
• Oral Microbiome Metabolism

  2015cites this paper
• Inactivating effects of the lactoperoxidase system on bacterial lyases involved in oral malodour production.

  2015cites this paper
• Purification and Characterization of Methionine Gamma Lyase-Deaminase(Mgld) from the Oral Pathogenic Organism Porphyromonas gingivalis

  2015cites this paper
• Molecular cloning and characterization of l-methionine γ-lyase from Streptomyces avermitilis.

  2015cites this paper
• L-Methionase: A Therapeutic Enzyme to Treat Malignancies

  2014cites this paper
• Crystal structure of the external aldimine of Citrobacter freundii methionine γ-lyase with glycine provides insight in mechanisms of two stages of physiological reaction and isotope exchange of α- and β-protons of competitive inhibitors.

  2014cites this paper
• Volatile metabolites of pathogens – a Systematic review Plos Pathogens 2013

  2014cites this paper
• Effects of metal salts on odour, pathogens, dewaterability and orthophosphate during the anaerobic digestion of municipal waste sludge

  2014cites this paper
• The bacterial metabolic processes that produce volatile sulfur compounds in the oral cavity

  2014cites this paper
• Supervised machine learning-based classification of oral malodor based on the microbiota in saliva samples

  2014cites this paper
• Metabolic fingerprint of dimethyl sulfone (DMSO2) in microbial-mammalian co-metabolism.

  2014cites this paper
• The role of Porphyromonas gingivalis in the regulation of epithelial-mesenchymal transition markers in migration.

  2014cites this paper
• METHIONINE- γ-LYASE (MGL) - ROLE IN COMBATING CANCER KOLASANI PAVANI 1 * AND S. VIJAYA SARADHI 2

  2014cites this paper
• Interleukin-6 production and epithelial cell signaling by telomerase immortalized gingival keratinocytes in Porphyromonas gingivalis infection.

  2014cites this paper
• Statistical Approach of Functional Profiling for a Microbial Community

  2014cites this paper
• Enhancement of Odor Removal and Dewaterability of Anaerobically Digested Sludge by Protease Addition

  2014cites this paper
• Detection of volatile malodorous compounds in breath: current analytical techniques and implications in human disease.

  2014cites this paper
• Pre-steady-state Kinetic and Structural Analysis of Interaction of Methionine γ-Lyase from Citrobacter freundii with Inhibitors*

  2014cites this paper
• Alliin is a suicide substrate of Citrobacter freundii methionine γ-lyase: structural bases of inactivation of the enzyme.

  2014cites this paper
• Infection with Porphyromonas gingivalis Exacerbates Endothelial Injury in Obese Mice

  2014cites this paper
• Methionine Metabolism: Major Pathways and Enzymes Involved and Strategies for Control and Diversification of Volatile Sulfur Compounds in Cheese

  2013cites this paper
• Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

  2013cites this paper
• Effect of Citrus aurantifolia swingle essential oils on methyl mercaptan production of Porphyromonas gingivalis triggering halitosis

  2013cites this paper
• Statistical methods for functional metagenomic analysis based on next-generation sequencing data

  2013cites this paper
• Volatile Metabolites of Pathogens: A Systematic Review

  2013cites this paper
• Kinetic Parameters and Cytotoxic Activity of Recombinant Methionine γ-Lyase from Clostridium tetani, Clostridium sporogenes, Porphyromonas gingivalis and Citrobacter freundii

  2013cites this paper
• Identification of methionine γ-lyase in genomes of some pathogenic bacteria

  2012cites this paper
• Assays for methionine γ-lyase and S-adenosyl-L-homocysteine hydrolase based on enzymatic formation of CdS quantum dots in situ.

  2012cites this paper
• The Role of Amino Acid Residues in the Active Site of L-Methionine γ-lyase from Pseudomonas putida

  2012cites this paper
• Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine γ-lyase with substrates

  2011cites this paper
• Exploring methionine γ-lyase structure-function relationship via microspectrophotometry and X-ray crystallography.

  2011cites this paper
• Effects of a composition containing lactoferrin and lactoperoxidase on oral malodor and salivary bacteria: a randomized, double-blind, crossover, placebo-controlled clinical trial

  2011cites this paper
• Characterization and immobilization of purified Aspergillus flavipesl‐methioninase: continuous production of methanethiol

  2011cites this paper
• Virulence Factors of the Oral Spirochete Treponema denticola

  2011influential citation
• Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586.

  2010cites this paper
• Porphyromonas gingivalis Virulence in a Drosophila melanogaster Model

  2010cites this paper
• Comparison of the Use of the Halimeter and the Oral Chroma™ in the Assessment of the Ability of Common Cultivable Oral Anaerobic Bacteria to Produce Malodorous Volatile Sulfur Compounds from Cysteine and Methionine

  2010cites this paper
• Modelling the effects of pH on tongue biofilm using a sorbarod biofilm perfusion system

  2010cites this paper
• Engineering input/output nodes in prokaryotic regulatory circuits.

  2010cites this paper
• Porphyromonas gingivalis-Host Interactions in a Drosophila melanogaster Model

  2010cites this paper
• Bacteroides, Prevotella, and Porphyromonas

  2010cites this paper
• Vaccination targeting surface FomA of Fusobacterium nucleatum against bacterial co-aggregation: Implication for treatment of periodontal infection and halitosis.

  2010cites this paper
• Modeling Volatile Organic Sulfur Compounds In Anaerobic Digestion

  2010cites this paper