Age‐related differences in brain network activation and co‐activation during multiple object tracking

Multiple object tracking (MOT) is a powerful paradigm for measuring sustained attention. Although previous fMRI studies have delineated the brain activation patterns associated with tracking and documented reduced tracking performance in aging, age‐related effects on brain activation during MOT have not been characterized. In particular, it is unclear if the task‐related activation of different brain networks is correlated, and also if this coordination between activations within brain networks shows differential effects of age.

• Publication year

  2016

• Venue

  Brain and Behavior

• Publication date

  2016-09-07

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1002/brb3.533PMID 27843692PMCID 5102637
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Aging Effects on Whole-Brain Functional Connectivity in Adults Free of Cognitive and Psychiatric Disorders.

  2016cited by this paper
• Age‐related differences in brain network activation and co‐activation during multiple object tracking

  2016cited by this paper
• On the existence of a generalized non-specific task-dependent network

  2015cited by this paper
• Attentional load modulates large-scale functional brain connectivity beyond the core attention networks

  2015cited by this paper
• Evaluation of ICA-AROMA and alternative strategies for motion artifact removal in resting state fMRI

  2015cited by this paper
• Automatic denoising of functional MRI data: Combining independent component analysis and hierarchical fusion of classifiers

  2014cited by this paper
• Wechsler Abbreviated Scale of Intelligence

  2014cited by this paper
• Functional connectivity and brain activation: a synergistic approach.

  2014cited by this paper
• Modulatory interactions between the default mode network and task positive networks in resting-state

  2014cited by this paper
• Decreased segregation of brain systems across the healthy adult lifespan

  2014cited by this paper
• Human cognitive aging: Corriger la fortune?

  2014cited by this paper
• Functional and structural architecture of the human dorsal frontoparietal attention network

  2013cited by this paper
• The Structure of Cognition: Attentional Episodes in Mind and Brain

  2013cited by this paper
• Normal Aging Delays and Compromises Early Multifocal Visual Attention during Object Tracking

  2013cited by this paper
• Functional brain connectivity and cognition: effects of adult age and task demands.

  2013cited by this paper
• Brain Connectivity and Visual Attention

  2013cited by this paper
• Default network modulation and large-scale network interactivity in healthy young and old adults.

  2012cited by this paper
• Imaging the default mode network in aging and dementia.

  2012cited by this paper
• Network-specific effects of age and in-scanner subject motion: A resting-state fMRI study of 238 healthy adults

  2012cited by this paper
• The Default Mode Network in Healthy Aging and Alzheimer's Disease

  2011cited by this paper
• Neuroimaging of Healthy Cognitive Aging

  2011cited by this paper
• Human neuroscience and the aging mind: a new look at old problems.

  2010cited by this paper
• The Factor Structure and Age-Related Factorial Invariance of the Delis-Kaplan Executive Function System (D-KEFS)

  2010cited by this paper
• Default network activity, coupled with the frontoparietal control network, supports goal-directed cognition

  2010cited by this paper
• Intellectual abilities in Alzheimer's disease patients: Contributions from the Wechsler Abbreviated Scale of Intelligence (WASI)

  2010cited by this paper
• Longitudinal evidence for diminished frontal cortex function in aging

  2010cited by this paper
• Functional Alterations in Memory Networks in Early Alzheimer’s Disease

  2010cited by this paper
• Using fMRI to distinguish components of the multiple object tracking task.

  2009cited by this paper
• Amyloid deposition is associated with impaired default network function in older persons without dementia.

  2009cited by this paper
• Distinct patterns of brain activity in young carriers of the APOE-ε4 allele

  2009cited by this paper
• Performance level modulates adult age differences in brain activation during spatial working memory

  2009cited by this paper
• Functional connectivity of default mode network components: Correlation, anticorrelation, and causality

  2009cited by this paper
• Accurate and robust brain image alignment using boundary-based registration

  2009cited by this paper
• The Common Neural Basis of Autobiographical Memory, Prospection, Navigation, Theory of Mind, and the Default Mode: A Quantitative Meta-analysis

  2009cited by this paper
• Reduced resting-state brain activity in the "default network" in normal aging.

  2008influential reference
• Distinct causal influences of parietal versus frontal areas on human visual cortex: evidence from concurrent TMS-fMRI.

  2008cited by this paper
• Independent component model of the default-mode brain function: combining individual-level and population-level analyses in resting-state fMRI.

  2008cited by this paper
• The reorienting system of the human brain: from environment to theory of mind.

  2008cited by this paper
• Functional coactivation map of the human brain.

  2008cited by this paper
• Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation

  2008cited by this paper
• Age-Related Changes in Attentional Tracking of Multiple Moving Objects

  2008cited by this paper
• Non-linear optimisation FMRIB Technial Report TR 07 JA 1

  2007cited by this paper
• Extrinsic and intrinsic systems in the posterior cortex of the human brain revealed during natural sensory stimulation.

  2007cited by this paper
• Disruption of large-scale brain systems in advanced aging.

  2007cited by this paper
• Non-linear registration aka Spatial normalisation

  2007cited by this paper
• Age Differences in Deactivation: A Link to Cognitive Control?

  2007cited by this paper
• Aging and Visual Attention

  2007cited by this paper
• TEST REVIEW: Dean C. Delis, Edith Kaplan & Joel H. Kramer, Delis Kaplan Executive Function System (D-KEFS), The Psychological Corporation, San Antonio, TX, 2001. $415.00 (complete kit)

  2006cited by this paper
• Age-related Changes in Brain Activity across the Adult Lifespan

  2006cited by this paper
• Age-related differences in multiple-object tracking.

  2005cited by this paper
• The human brain is intrinsically organized into dynamic, anticorrelated functional networks.

  2005influential reference
• Brain aging: reorganizing discoveries about the aging mind.

  2005cited by this paper
• Top-down suppression deficit underlies working memory impairment in normal aging

  2005cited by this paper
• Task-independent and task-specific age effects on brain activity during working memory, visual attention and episodic retrieval.

  2004cited by this paper
• Probabilistic independent component analysis for functional magnetic resonance imaging

  2004influential reference
• Episodic memory change in late adulthood: Generalizability across samples and performance indices

  2004cited by this paper
• Advances in functional and structural MR image analysis and implementation as FSL.

  2004cited by this paper
• A Parametric Manipulation of Factors Affecting Task-induced Deactivation in Functional Neuroimaging

  2003cited by this paper
• Neuroimaging Studies of Attention: From Modulation of Sensory Processing to Top-Down Control

  2003cited by this paper
• A Cortical Mechanism for Triggering Top-Down Facilitation in Visual Object Recognition

  2003cited by this paper
• Functional deactivations: Change with age and dementia of the Alzheimer type

  2003cited by this paper
• Aging Gracefully: Compensatory Brain Activity in High-Performing Older Adults

  2002cited by this paper
• Control of goal-directed and stimulus-driven attention in the brain

  2002cited by this paper
• Neurotechnique Whole Brain Segmentation: Automated Labeling of Neuroanatomical Structures in the Human Brain

  2002cited by this paper
• Under-recruitment and nonselective recruitment: dissociable neural mechanisms associated with aging.

  2002cited by this paper
• Inaugural Article: A default mode of brain function

  2001influential reference
• Attention response functions: characterizing brain areas using fMRI activation during parametric variations of attentional load.

  2001cited by this paper
• Brain Areas Specific for Attentional Load in a Motion-Tracking Task

  2001cited by this paper
• A global optimisation method for robust affine registration of brain images

  2001cited by this paper
• The handbook of aging and cognition

  2001cited by this paper
• Mechanisms of visual attention in the human cortex.

  2000cited by this paper
• Voluntary orienting is dissociated from target detection in human posterior parietal cortex

  2000cited by this paper
• Attention and Aging: A Functional Perspective

  2000cited by this paper
• The generality of parietal involvement in visual attention.

  1999cited by this paper
• Age-related changes in processing auditory stimuli during visual attention: evidence for deficits in inhibitory control and sensory memory.

  1999cited by this paper
• A large-scale distributed network for covert spatial attention: further anatomical delineation based on stringent behavioural and cognitive controls.

  1999cited by this paper
• Cortical fMRI activation produced by attentive tracking of moving targets.

  1998cited by this paper
• Common Blood Flow Changes across Visual Tasks: II. Decreases in Cerebral Cortex

  1997influential reference
• The Psychophysics Toolbox.

  1997cited by this paper
• Emergence of a powerful connection between sensory and cognitive functions across the adult life span: a new window to the study of cognitive aging?

  1997cited by this paper
• The VideoToolbox software for visual psychophysics: transforming numbers into movies.

  1997cited by this paper
• Aging, stimulus identification and the effect of probability: an event-related potential study.

  1996cited by this paper
• Using Fmri to Distinguish Components of the Multiple Object Tracking Task

  1994cited by this paper
• How to Detect and Handle Outliers

  1993influential reference
• Tracking multiple independent targets: evidence for a parallel tracking mechanism.

  1988cited by this paper
• Philosophical Transactions of the Royal Society, Special Issue on ’Multimodal neuroimaging of brain connectivity’)

  year unknowncited by this paper

• A common signal-strength factor limits awareness and precise knowledge of multiple moving objects across the adult lifespan.

  2026cites this paper
• The default mode network throughout the lifespan: A state-of-the-art scoping review on its development and association to individual cognitive functioning

  2026cites this paper
• Translation of task-evoked negative BOLD response into aging and Alzheimer's disease: a systematic review of the current literature

  2025cites this paper
• Predicting Mental and Neurological Illnesses Based on Cerebellar Normative Features

  2025cites this paper
• Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence

  2024cites this paper
• Broadscale dampening of uncertainty adjustment in the aging brain

  2024cites this paper
• RKHS-based Latent Position Random Graph Correlation

  2023cites this paper
• Effects of acute exercise fatigue on the spatiotemporal dynamics of resting-state large-scale brain networks

  2023cites this paper
• Relationship between dynamic visual acuity and multiple object tracking performance

  2022cites this paper
• Inhibition of emotions in healthy aging: age‐related differences in brain network connectivity

  2021cites this paper
• Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adults

  2021cites this paper
• Neuroimaging Functional Magnetic Resonance Imaging Task‐Based Dorsolateral Prefrontal Cortex Activation Following 12 Weeks of Cosmos caudatus Supplementation Among Older Adults With Mild Cognitive Impairment

  2021cites this paper
• NeuroTracker Three-Dimensional Multiple Object Tracking (3D-MOT): A Tool to Improve Concentration and Game Performance among Basketball Athletes

  2021cites this paper
• Reliability, sensitivity, and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors

  2020cites this paper
• The Aging Brain and Executive Functions Revisited: Implications from Meta-Analytic and Functional-Connectivity Evidence

  2020cites this paper
• Functional brain network modeling in sub-acute stroke patients and healthy controls during rest and continuous attentive tracking

  2019cites this paper
• Title : A randomized , double blind study of computerized cognitive training in combination with transcranial direct current stimulation ( tDCS ) in stroke patients – utility of fMRI as marker for training outcome

  2019cites this paper
• The genetic architecture of human brainstem structures and their involvement in common brain disorders

  2019cites this paper
• Pupillometry as an Objective Measure of Sustained Attention in Young and Older Listeners

  2019cites this paper
• Reliability, sensitivity and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors

  2019cites this paper
• Neural efficiency in basketball players is associated with bidirectional reductions in cortical activation and deactivation during multiple-object tracking task performance.

  2019cites this paper
• The role of norepinephrine in the pathophysiology of schizophrenia.

  2019cites this paper
• The application of multiple object tracking in the evaluation and training of different populations

  2019influential citation
• Making Balance Automatic Again: Using Dual Tasking as an Intervention in Balance Rehabilitation for Older Adults

  2018cites this paper
• Default‐mode network dynamics are restricted during high speed discrimination in healthy aging: Associations with neurocognitive status and simulated driving behavior

  2018influential citation
• Can Blood Oxygenation Level Dependent Functional Magnetic Resonance Imaging Be Used Accurately to Compare Older and Younger Populations? A Mini Literature Review

  2018cites this paper
• Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry

  2018cites this paper
• Dual-Task Rehabilitation: The Science of Prioritization, Compensation, and Rehabilitating Dual-Task Tolerance in Geriatrics

  2018cites this paper
• Genetics of brain age suggest an overlap with common brain disorders

  2018cites this paper
• Mindful breath awareness meditation facilitates efficiency gains in brain networks: A steady-state visually evoked potentials study

  2018cites this paper
• Different effects of aging and gender on the temporal resolution in attentional tracking.

  2017cites this paper
• Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples

  2017cites this paper
• Increased sensitivity to age‐related differences in brain functional connectivity during continuous multiple object tracking compared to resting‐state

  2017cites this paper
• Increased default-mode variability is related to reduced task-performance and is evident in adults with ADHD

  2017cites this paper
• Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders

  2016cites this paper
• Age‐related differences in brain network activation and co‐activation during multiple object tracking

  2016cites this paper