Distinct Cellular Loci for the ABCA1-Dependent and ABCA1-Independent Lipid Efflux Mediated by Endogenous Apolipoprotein E Expression

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  2006-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.ATV.0000193627.12516.1dPMID 16254198
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pharmacological regulation of cholesterol efflux in human monocyte-derived macrophages in the absence of exogenous cholesterol acceptors.

  2005cited by this paper
• The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I.

  2005cited by this paper
• ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects.

  2005cited by this paper
• Abca7 Null Mice Retain Normal Macrophage Phosphatidylcholine and Cholesterol Efflux Activity despite Alterations in Adipose Mass and Serum Cholesterol Levels*

  2005cited by this paper
• Lipid efflux in human and mouse macrophagic cells: evidence for differential regulation of phospholipid and cholesterol efflux Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M400482-JLR200

  2005cited by this paper
• Molecular interactions between apoE and ABCA1: impact on apoE lipidation.

  2004cited by this paper
• Human ABCA7 Supports Apolipoprotein-mediated Release of Cellular Cholesterol and Phospholipid to Generate High Density Lipoprotein*

  2004cited by this paper
• The Establishment of Telomerase-immortalized Tangier Disease Cell Lines Indicates the Existence of an Apolipoprotein A-I-inducible but ABCA1-independent Cholesterol Efflux Pathway*

  2004cited by this paper
• ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

  2004cited by this paper
• ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux Published, JLR Papers in Press, November 16, 2003. DOI 10.1194/jlr.M300355-JLR200

  2004cited by this paper
• ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions Published, JLR Papers in Press, April 16, 2003. DOI 10.1194/jlr.M300078-JLR200

  2003cited by this paper
• ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux*

  2003cited by this paper
• Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.M200475-JLR200

  2003cited by this paper
• Expression of scavenger receptor BI facilitates sterol movement between the plasma membrane and the endoplasmic reticulum in macrophages.

  2003cited by this paper
• Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues

  2002cited by this paper
• Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages

  2002cited by this paper
• Regulation and mechanisms of macrophage cholesterol efflux.

  2002cited by this paper
• ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression.

  2002cited by this paper
• ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte‐derived macrophages

  2001cited by this paper
• ATP-binding Cassette Transporter A1 Contains an NH2-terminal Signal Anchor Sequence That Translocates the Protein's First Hydrophilic Domain to the Exoplasmic Space*

  2001cited by this paper
• The human ATP-binding cassette (ABC) transporter superfamily.

  2001cited by this paper
• Sterol Efflux Mediated by Endogenous Macrophage ApoE Expression Is Independent of ABCA1

  2001cited by this paper
• Mass spectrometric analysis reveals an increase in plasma membrane polyunsaturated phospholipid species upon cellular cholesterol loading.

  2001cited by this paper
• Role of ABCG1 and other ABCG family members in lipid metabolism.

  2001cited by this paper
• Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice

  2000cited by this paper
• Apolipoprotein E and atherosclerosis.

  2000cited by this paper
• Transport and Processing of Endogenously Synthesized ApoE on the Macrophage Cell Surface*

  2000cited by this paper
• Free Cholesterol Loading of Macrophages Induces Apoptosis Involving the Fas Pathway*

  2000cited by this paper
• Scavenger receptor BI and cholesterol trafficking.

  1999cited by this paper
• Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation.

  1999cited by this paper
• Apolipoprotein E-dependent cholesterol efflux from macrophages: kinetic study and divergent mechanisms for endogenous versus exogenous apolipoprotein E.

  1999cited by this paper
• Degradation of Macrophage ApoE in a Nonlysosomal Compartment

  1997cited by this paper
• Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages.

  1997cited by this paper
• Use of cyclodextrins for manipulating cellular cholesterol content.

  1997cited by this paper
• Apolipoprotein E secretion by macrophages: its potential physiological functions

  1996cited by this paper
• Serum albumin is a significant intermediate in cholesterol transfer between cells and lipoproteins.

  1996cited by this paper
• Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3.

  1994cited by this paper
• Apolipoprotein E localization in human coronary atherosclerotic plaques by in situ hybridization and immunohistochemistry and comparison with lipoprotein lipase.

  1994cited by this paper
• Post-translational regulation of macrophage apoprotein E production.

  1992cited by this paper

• APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease

  2020cites this paper
• Apoprotein E and Reverse Cholesterol Transport

  2018cites this paper
• LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo

  2018cites this paper
• Low lysosomal acid lipase activity in smooth muscle cells relative to macrophages provides new insights into foam cell formation in atherosclerosis

  2018cites this paper
• ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis

  2016cites this paper
• Astrocyte׳s endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA1.

  2014cites this paper
• Effect of repeated apoA-IMilano/POPC infusion on lipids, (apo)lipoproteins, and serum cholesterol efflux capacity in cynomolgus monkeys[S]

  2013cites this paper
• APOE genotype modifies the association between plasma omega-3 fatty acids and plasma lipids in the Multi-Ethnic Study of Atherosclerosis (MESA).

  2013cites this paper
• APOE genotype modifies the association between plasma measured omega-3 fatty acids and plasma lipids in the Multi-Ethnic Study of Atherosclerosis (MESA)

  2013cites this paper
• Apolipoprotein E gene polymorphism influences aggressive behavior in prostate cancer cells by deregulating cholesterol homeostasis

  2013cites this paper
• ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice

  2013cites this paper
• General discussion and considerations

  2012cites this paper
• Apolipoprotein E4 Domain Interaction Accelerates Diet-Induced Atherosclerosis in Hypomorphic Arg-61 Apoe Mice

  2012cites this paper
• Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt.

  2012cites this paper
• Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies

  2012cites this paper
• Role of Apolipoprotein E, Scavenger Receptor class B type I and ATP-Binding Cassette Transporter G1 in Reverse Cholesterol Transport and atherosclerosis

  2012cites this paper
• Apolipoprotein E4 Is Deficient in Inducing Macrophage ABCA1 Expression and Stimulating the Sp1 Signaling Pathway

  2012cites this paper
• Apolipoprotein A-I stimulates cholesteryl ester transfer protein and apolipoprotein E secretion from lipid-loaded macrophages; the role of NF-κB and PKA signaling pathways.

  2011cites this paper
• The ABC transporters in lipid flux and atherosclerosis.

  2011cites this paper
• Apolipoprotein E inhibits toll-like receptor (TLR)-3- and TLR-4-mediated macrophage activation through distinct mechanisms.

  2010cites this paper
• Anti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH(2).

  2010cites this paper
• High density lipoprotein structure-function and role in reverse cholesterol transport.

  2010cites this paper
• ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance[S]

  2010cites this paper
• Recent advances on the antiatherogenic effects of HDL-derived proteins and mimetic peptides.

  2009cites this paper
• Adhesion without Engaging CXCL16-Dependent Cell Transmembrane Chemokine CXCL16 Human Macrophages by Up-Regulating in Lipoprotein Uptake and Cholesterol Efflux Atherogenic Lipids Induce High-Density

  2009cites this paper
• Absence of ApoE Upregulates Murine Brain ApoD and ABCA1 Levels, But Does Not Affect Brain Sterol Levels, While Human ApoE3 and Human ApoE4 Upregulate Brain Cholesterol Precursor Levels

  2009cites this paper
• Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland.

  2009cites this paper
• Inhibition of ERK1/2 and Activation of Liver X Receptor Synergistically Induce Macrophage ABCA1 Expression and Cholesterol Efflux*

  2009cites this paper
• Atherogenic Lipids Induce High-Density Lipoprotein Uptake and Cholesterol Efflux in Human Macrophages by Up-Regulating Transmembrane Chemokine CXCL16 without Engaging CXCL16-Dependent Cell Adhesion1

  2009cites this paper
• Regulation of endogenous apolipoprotein E secretion by macrophages.

  2008cites this paper
• Lysophosphatidylcholine promotes cholesterol efflux from mouse macrophage foam cells via PPARgamma-LXRalpha-ABCA1-dependent pathway associated with apoE.

  2007cites this paper
• Diet effects on atherosclerosis in mice.

  2007cites this paper
• Cellular sphingolipids regulate macrophage apolipoprotein E secretion.

  2007cites this paper
• Lysophosphatidylcholine promotes cholesterol efflux from mouse macrophage foam cells via PPARγ‐LXRα‐ABCA1‐dependent pathway associated with apoE

  2007cites this paper
• Nutritional regulation of adipose tissue apolipoprotein E expression.

  2007cites this paper
• El monocito/macrófago como diana terapéutica en la aterosclerosis

  2007cites this paper
• Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor Published, JLR Papers in Press, November 1, 2006.

  2007cites this paper
• A Pathway-Dependent on ApoE, ApoAI, and ABCA1 Determines Formation of Buoyant High-Density Lipoprotein by Macrophage Foam Cells

  2007cites this paper
• Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

  2007cites this paper
• Simultaneous isolation of total cellular lipids and RNA from cultured cells.

  2006cites this paper
• Decreased Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice Transplanted With Abcg1−/− Bone Marrow

  2006cites this paper