A Molecular Basis for Natural Selection at the timeless Locus in Drosophila melanogaster

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Science

• Publication date

  2007-06-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/science.1138426PMID 17600216
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Natural Selection Favors a Newly Derived timeless Allele in Drosophila melanogaster

  2007cited by this paper
• Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila's circadian clock

  2006cited by this paper
• Roles of the Two Drosophila CRYPTOCHROME Structural Domains in Circadian Photoreception

  2004cited by this paper
• A constitutively active cryptochrome in Drosophila melanogaster

  2004cited by this paper
• A Fly's Eye View of Circadian Entrainment

  2003cited by this paper
• A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock.

  2001cited by this paper
• The circadian clock of fruit flies is blind after elimination of all known photoreceptors.

  2001cited by this paper
• Photic Signaling by Cryptochrome in the DrosophilaCircadian System

  2001cited by this paper
• Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY.

  2001cited by this paper
• A unique circadian-rhythm photoreceptor.

  2000cited by this paper
• Drosophila cryptochromes: A unique circadian-rhythm photoreceptor

  2000cited by this paper
• Light-dependent sequestration of TIMELESS by CRYPTOCHROME.

  1999cited by this paper
• The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila.

  1998cited by this paper
• Conceptual translation of timeless reveals alternative initiating methionines in Drosophila.

  1997cited by this paper
• Molecular anatomy of a light-sensitive circadian pacemaker in Drosophila.

  1996cited by this paper
• A light-entrainment mechanism for the Drosophila circadian clock

  1996cited by this paper
• Temporal phosphorylation of the Drosophila period protein.

  1994cited by this paper
• The Amplitude of Circadian Oscillations: Temperature Dependence, Latitudinal Clines, and the Photoperiodic Time Measurement

  1991cited by this paper
• Latitudinal Clines in the Properties of a Circadian Pacemaker

  1989cited by this paper

• Geographic Divergence and the Genomic Basis of Reproductive Diapause in Drosophila triauraria

  2026cites this paper
• Splicing of a core clock gene regulates seasonal adaptations by a winter gating mechanism

  2025cites this paper
• Cold-Sensing TRP Channels and Temperature Preference Modulate Ovarian Development in the Model Organism Drosophila melanogaster

  2025cites this paper
• Insect circadian plasticity as a proposed target for the expression of parasite extended phenotypes

  2025cites this paper
• Functional polymorphism of CYCLE underlies the diapause variation in moths.

  2025cites this paper
• Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster

  2025cites this paper
• Coevolution of Drosophila-type timeless with partner clock proteins

  2025cites this paper
• Revealing the profound influence of diapause on gene expression: Insights from the annual transcriptome of the copepod Calanus finmarchicus

  2024cites this paper
• Evaluating the Adaptive Fitness of Circadian Clocks and their Evolution

  2024cites this paper
• The period gene alters daily and seasonal timing in Ostrinia nubilalis

  2024cites this paper
• Neuropeptide dynamics coordinate layered plasticity mechanisms adapting Drosophila circadian behavior to changing environment

  2024cites this paper
• Dissecting the Interaction between Cryptochrome and Timeless Reveals Underpinnings of Light-Dependent Recognition.

  2024cites this paper
• Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes.

  2023cites this paper
• Drosophila ezoana uses morning and evening oscillators to adjust its rhythmic activity to different daylengths but only the morning oscillator to measure night length for photoperiodic responses

  2023cites this paper
• Unveiling Subtle Geographical Clines: Phenotypic Effects and Dynamics of Circadian Clock Gene Polymorphisms

  2023cites this paper
• Mutation of the clock gene timeless disturbs diapause induction and adult emergence rhythm in Helicoverpa armigera.

  2023cites this paper
• Integration of photoperiodic and temperature cues by the circadian clock to regulate insect seasonal adaptations

  2023cites this paper
• Neanderthal Introgression Shaped Human Circadian Traits

  2023cites this paper
• Natural alleles of the clock gene timeless differentially affect life-history traits in Drosophila

  2023influential citation
• Editorial: Biological rhythms: Evolution, population biology, and adaptation

  2023cites this paper
• Archaic Introgression Shaped Human Circadian Traits

  2023cites this paper
• Cryptochrome–Timeless structure reveals circadian clock timing mechanisms

  2023cites this paper
• Clock-talk: have we forgotten about geographic variation?

  2023cites this paper
• Morning and evening oscillators cooperate to reset circadian Morning and evening oscillators cooperate to reset circadian behavior in response to light input behavior in response to light input us know how access to this document benefits you.

  2022cites this paper
• Plate Section (PDF Only)

  2022cites this paper
• Enhanced germline stem cell longevity in Drosophila diapause

  2022cites this paper
• Pool-GWAS on reproductive dormancy in Drosophila simulans suggests a polygenic architecture

  2022cites this paper
• Light triggers a network switch between circadian morning and evening oscillators controlling behaviour during daily temperature cycles

  2022cites this paper
• The circadian clock conveys thermal and photoperiodic cues to modulate EYES ABSENT via the neuropeptide PDF to regulate seasonal physiology

  2022cites this paper
• Nucleotide Variation in Drosophila cryptochrome Is Linked to Circadian Clock Function: An Association Analysis

  2022cites this paper
• Partial reuse of circadian clock genes along parallel clines of diapause in two moth species

  2022influential citation
• Adaptation of Drosophila melanogaster to Long Photoperiods of High-Latitude Summers Is Facilitated by the ls-Timeless Allele

  2022cites this paper
• Photoperiodic time measurement, photoreception, and circadian clocks in insect photoperiodism

  2022cites this paper
• Mechanistic insight into light-dependent recognition of Timeless by Drosophila cryptochrome

  2021cites this paper
• Roles of peripheral clocks: lessons from the fly

  2021cites this paper
• Timeless in animal circadian clocks and beyond

  2021cites this paper
• Neuroendocrine Regulation of Reproductive Dormancy in the Fruit Fly Drosophila melanogaster: A Review of Juvenile Hormone-Dependent Regulation

  2021cites this paper
• The opposing Chloride Cotransporters KCC and NKCC control locomotor activity in constant light and during long days

  2021cites this paper
• Local adaptation of life cycles in a butterfly is associated with variation in several circadian clock genes

  2021cites this paper
• A latitudinal cline in a courtship song character of Drosophila melanogaster

  2021cites this paper
• Induction of diapause by clock proteins period and timeless via changes in PTTH and ecdysteroid titer in the sugar beet moth, Scrobipalpa ocellatella (Lepidoptera: Gelechiidae).

  2021cites this paper
• Disrupted Glutamate Signaling in Drosophila Generates Locomotor Rhythms in Constant Light

  2020cites this paper
• Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS.

  2020cites this paper
• Unique genetic signatures of local adaptation over space and time for diapause, an ecologically relevant complex trait, in Drosophila melanogaster

  2020cites this paper
• A temperature-dependent molecular switch to adjust behavior to changing environmental conditions

  2020cites this paper
• One Actor, Multiple Roles: The Performances of Cryptochrome in Drosophila

  2020cites this paper
• EYES ABSENT and TIMELESS integrate photoperiodic and temperature cues to regulate seasonal physiology in Drosophila

  2020cites this paper
• Model and Non-model Insects in Chronobiology

  2020cites this paper
• A natural timeless polymorphism allowing circadian clock synchronization in “white nights”

  2020cites this paper
• The genetic architecture underlying diapause termination in a planktonic crustacean

  2019influential citation
• Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster

  2019cites this paper
• Evolutionary and functional genetics of insect diapause: a call for greater integration.

  2019cites this paper
• Temperature synchronization of the Drosophila circadian clock protein PERIOD is controlled by the TRPA channel PYREXIA

  2019cites this paper
• Peptidergic signaling from clock neurons regulates reproductive dormancy in Drosophila melanogaster

  2019cites this paper
• Adaptive Differences in Circadian Clock Gene Expression Patterns and Photoperiodic Diapause Induction in Nasonia vitripennis

  2019cites this paper
• A Distinct Visual Pathway Mediates High-Intensity Light Adaptation of the Circadian Clock in Drosophila

  2019cites this paper
• Involvement of clock genes in seasonal, circadian and ultradian rhythms of Nasonia vitripennis

  2018cites this paper
• A Semi-natural Approach for Studying Seasonal Diapause in Drosophila melanogaster Reveals Robust Photoperiodicity

  2018cites this paper
• Diapause in Drosophila melanogaster - Photoperiodicity, cold tolerance and metabolites.

  2018cites this paper
• Photosensitive Alternative Splicing of the Circadian Clock Gene timeless Is Population Specific in a Cold-Adapted Fly, Drosophila montana

  2018cites this paper
• Molecular analysis of circadian photosensitivity and diapause in the jewel wasp Nasonia vitripennis

  2018cites this paper
• Flies as models for circadian clock adaptation to environmental challenges

  2018cites this paper
• The molecular basis of diel and seasonal rhythmicity in the copepod Calanus finmarchicus

  2018cites this paper
• Calanus finmarchicus seasonal cycle and diapause in relation to gene expression, physiology, and endogenous clocks

  2018cites this paper
• Calanus finmarchicus diel and seasonal rhythmicity in relation to endogenous timing under extreme polar photoperiods

  2018cites this paper
• Inverse European Latitudinal Cline at the timeless Locus of Drosophila melanogaster Reveals Selection on a Clock Gene: Population Genetics of ls-tim

  2018cites this paper
• Characterisation, analysis of expression and localisation of circadian clock genes from the perspective of photoperiodism in the aphid Acyrthosiphon pisum.

  2017cites this paper
• Mapping Quantitative Trait Loci Underlying Circadian Light Sensitivity in Drosophila

  2017influential citation
• RETRACTED: Calcium and SOL Protease Mediate Temperature Resetting of Circadian Clocks

  2017cites this paper
• Geographical analysis of diapause inducibility in European Drosophila melanogaster populations.

  2017influential citation
• Evolution: Fruit Fly Clocks on the Edge

  2017cites this paper
• Insects at Not So Low Temperature : Climate Change in the Temperate Zone and Its Biotic Consequences

  2017influential citation
• Is diapause an ancient adaptation in Drosophila?

  2017cites this paper
• The Drosophila Clock System

  2017cites this paper
• Watching the clock for 25 years in FlyClockbase: Variability in circadian clocks of Drosophila melanogaster as uncovered by biological model curation

  2017cites this paper
• Comparative transcriptomics support evolutionary convergence of diapause responses across Insecta

  2017cites this paper
• Adaptation of Circadian Neuronal Network to Photoperiod in High-Latitude European Drosophilids.

  2017cites this paper
• Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster

  2016cites this paper
• Advancing molecular crustacean chronobiology through the characterisation of the circadian clock in two malacostracan species, Euphausia superba and Parhyale hawaiensis

  2016cites this paper
• An Intronic Polymorphism in couch potato Is Not Distributed Clinally in European Drosophila melanogaster Populations nor Does It Affect Diapause Inducibility

  2016cites this paper
• GSK-3 Beta Does Not Stabilize Cryptochrome in the Circadian Clock of Drosophila

  2016cites this paper
• K-F. (2016). Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability. Proceedings of the National Academy of Sciences of the United States of America, 113(47), 13486-13491. DOI: 10.1073/pnas.1606547113

  2016cites this paper
• Reciprocal regulation of carbon monoxide metabolism and the circadian clock

  2016cites this paper
• The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

  2016cites this paper
• “The Environment is Everything That Isn't Me”: Molecular Mechanisms and Evolutionary Dynamics of Insect Clocks in Variable Surroundings

  2016cites this paper
• Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability

  2016cites this paper
• The genomic basis of circadian and circalunar timing adaptations in a midge

  2016cites this paper
• Explaining the sawtooth: latitudinal periodicity in a circadian gene correlates with shifts in generation number

  2015cites this paper
• Twilight Dominates Over Moonlight in Adjusting Drosophila’s Activity Pattern

  2015cites this paper
• Opsin clines in butterflies suggest novel roles for insect photopigments.

  2015cites this paper
• Evidence that natural selection maintains genetic variation for sleep in Drosophila melanogaster

  2015cites this paper
• Fast–slow continuum and reproductive strategies structure plant life-history variation worldwide

  2015cites this paper
• Control of Rest–Activity Behavior by the Central Clock in Drosophila

  2015cites this paper
• Genomic, Evolutionary and Functional Analyses of Diapause in Drosophila Melanogaster

  2015cites this paper
• period and timeless mRNA Splicing Profiles under Natural Conditions in Drosophila melanogaster

  2015cites this paper
• Drosophila americana Diapausing Females Show Features Typical of Young Flies

  2015cites this paper
• Loss of Drosophila melanogaster TRPA1 Function Affects “Siesta” Behavior but Not Synchronization to Temperature Cycles

  2015cites this paper
• Common features in diverse insect clocks

  2015cites this paper
• Calcium and SOL Protease Mediate Temperature Resetting of Circadian Clocks

  2015cites this paper
• Opsin Clines in Butterflies Suggest Novel Roles for Insect Photopigments

  2015cites this paper